Engineering Mouse Chromosomes with Cre-loxP: Range, Efficiency, and Somatic Applications

REFERENCES

• Agah, R., Frenkel, P. A., French, B. A., Michael, L. H., Overbeek, P. A., and Schneider, M. D.. 1997. Gene recombination in postmitotic cells. Targeted expression of Cre recombinase provokes cardiac-restricted, site-specific rearrangement in adult ventricular muscle in vivo. J. Clin. Investig. 100:169–179
   PubMed Web of Science ®Google Scholar
• Ashburner, M.. Drosophila: a laboratory handbook 1: Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y
   Google Scholar
• Baldini, A., and Lindsay, E. A.. 1989. Mapping human YAC clones by fluorescence in situ hybridization using Alu-PCR from single yeast colonies In situ hybridization protocols Choo, K. H. A. 33:75–84 Humana Press, Totowa, N.J
   Google Scholar
• Beumer, K. J., Pimpinelli, S., and Golic, K. G.. 1998. 1994. Induced chromosomal exchange directs the segregation of recombinant chromatids in mitosis of Drosophila. Genetics 150:173–188
   PubMedGoogle Scholar
• Chen, K. S., Manian, P., Koeuth, T., Potocki, L., Zhao, Q., Chinault, A. C., Lee, C. C., and Lupski, J. R.. 1997. Homologous recombination of a flanking repeat gene cluster is a mechanism for a common contiguous gene deletion syndrome. Nat. Genet. 17:154–163
   PubMed Web of Science ®Google Scholar
• Croce, C. M.. 1991. Genetic approaches to the study of the molecular basis of human cancer. Cancer Res. 51:5015s–5018s
   PubMedGoogle Scholar
• Korenberg, J. R., Chen, X. N., Schipper, R., Sun, Z., Gonsky, R., Gerwehr, S., Carpenter, N., Daumer, C., Dignan, P., Disteche, C. et al. 1994. Down syndrome phenotypes: the consequences of chromosomal imbalance. Proc. Natl. Acad. Sci. USA 91:4997–5001
   PubMed Web of Science ®Google Scholar
• Liu, P., Zhang, H., McLellan, A., Vogel, H., and Bradley, A.. 1998. Embryonic lethality and tumorigenesis caused by segmental aneuploidy on mouse Chromosome 11. Genetics 150:1155–1168
   PubMedGoogle Scholar
• Liu, X., Wu, H., Loring, J., Hormuzdi, S., Disteche, C. M., Bornstein, P., and Jaenisch, R.. 1997. Trisomy eight in ES cells is a common potential problem in gene targeting and interferes with germ line transmission. Dev. Dyn. 209:85–91
   PubMed Web of Science ®Google Scholar
• Lupski, J. R.. 1998. Genomic disorders: structural features of the genome can lead to DNA rearrangements and human disease traits. Trends Genet. 14:417–422
   PubMed Web of Science ®Google Scholar
• O'Gorman, S., Dagenais, N. A., Qian, M., and Marchuk, Y.. 1997. Protamine-Cre recombinase transgenes efficiently recombine target sequences in the male germ line of mice, but not in embryonic stem cells. Proc. Natl. Acad. Sci. USA 94:14602–14607
   PubMedGoogle Scholar
• Ramirez-Solis, R., Davis, A. C., and Bradley, A.. 1993. Gene targeting in embryonic stem cells. Methods Enzymol. 225:855–878
   PubMedGoogle Scholar
• Ramirez-Solis, R., Liu, P., and Bradley, A.. 1995. Chromosome engineering in mice. Nature 378:720–724
   PubMed Web of Science ®Google Scholar
• Rinchik, E. M., and Russell, L. B.. Germ-line deletion mutations in the mouse: tools for intensive functional and physical mapping of regions of the mammalian genome p. 121–158. In Davies, K. E., and Tilghman, S. M. Genome analysis, vol. 1. Genetic and physical mapping. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y
   Google Scholar
• Robertson, E. J.. 1990. Embryo-derived stem cell lines Teratocarcinomas and embryonic stem cells: a practical approach. Robertson, E. J. 1987. 71–112 IRL, Oxford, England
   Google Scholar
• Sauer, B.. 1998. Inducible gene targeting in mice using the Cre/lox system. Methods 14:381–392
   PubMed Web of Science ®Google Scholar
• Smith, A. J., De Sousa, M. A., Kwabi-Addo, B., Heppell-Parton, A., Impey, H., and Rabbitts, P.. 1995. A site-directed chromosomal translocation induced in embryonic stem cells by Cre-loxP recombination. Nat. Genet. 9:376–385
   PubMed Web of Science ®Google Scholar
• Sternberg, N. L.. 1992. Cloning high molecular weight DNA fragments by the bacteriophage P1 system. Trends Genet. 8:11–16
   PubMedGoogle Scholar
• Thomas, J. W., LaMantia, C., and Magnuson, T.. 1998. X-ray-induced mutations in mouse embryonic stem cells. Proc. Natl. Acad. Sci. USA 95:1114–1119
   PubMedGoogle Scholar
• Valancius, V., and Smithies, O.. 1991. Double-strand gap repair in a mammalian gene targeting reaction. Mol. Cell. Biol. 11:4389–4397
   PubMedGoogle Scholar
• Voziyanov, Y., Pathania, S., and Jayaram, M.. 1999. A general model for site-specific recombination by the integrase family recombinases. Nucleic Acids Res. 27:930–941
   PubMed Web of Science ®Google Scholar
• Yokoyama, T., Silversides, D. W., Waymire, K. G., Kwon, B. S., Takeuchi, T., and Overbeek, P. A.. 1990. Conserved cysteine to serine mutation in tyrosinase is responsible for the classical albino mutation in laboratory mice. Nucleic Acids Res. 18:7293–7298
   PubMedGoogle Scholar
• Zheng, B., Mills, A. A., and Bradley, A.. 1999. A system for rapid generation of coat color-tagged knockouts and defined chromosomal rearrangements in mice. Nucleic Acids Res. 27:2354–60
   PubMedGoogle Scholar
• Zheng, B., Sage, M., Cai, W. W., Thompson, D. M., Tavsanli, B. C., Cheah, Y. C., and Bradley, A.. 1999. Engineering a mouse balancer chromosome. Nat. Genet. 22:375–378
   PubMedGoogle Scholar