Ligand-Mediated Assembly and Real-Time Cellular Dynamics of Estrogen Receptor α-Coactivator Complexes in Living Cells

REFERENCES

• Barrack, E. R.. 1987. Steroid hormone receptor localization in the nuclear matrix: interaction with acceptor sites. J. Steroid Biochem. 27:115–121.
   PubMedGoogle Scholar
• Beato, M., S. Chavez, and M. Truss. 1996. Transcriptional regulation by steroid hormones. Steroids 61:240–251.
   PubMedGoogle Scholar
• Belmont, A. S., G. Li, G. Sudlow, and C. Robinett. 1999. Visualization of large-scale chromatin structure and dynamics using the lac operator/lac repressor reporter. Methods Cell Biol. 58:203–222.
   PubMed Web of Science ®Google Scholar
• Brzozowski, A. M., A. C. Pike, Z. Dauter, R. E. Hubbard, T. Bon, O. Engstrom, L. Ohman, G. L. Greene, J. A. Gustafsson, and M. Carlquist. 1997. Molecular basis of agonism and antagonism in the oestrogen receptor. Nature 389:753–758.
   PubMed Web of Science ®Google Scholar
• Chakravarti, D., V. J. LaMorte, M. C. Nelson, T. Nakajima, I. G. Schulman, H. Juguilon, M. Montminy, and R.M. Evans. 1996. Role of CBP/P300 in nuclear receptor signaling. Nature 383:99–103.
   PubMed Web of Science ®Google Scholar
• Cook, P. R.. 1999. The organization of replication and transcription. Science 284:1790–1795.
   PubMed Web of Science ®Google Scholar
• Danielian, P. S., R. White, J. A. Lees, and M. G. Parker. 1992. Identification of a conserved region required for hormone dependent transcriptional activation by steroid hormone receptors. EMBO J. 11:1025–1033.
   PubMed Web of Science ®Google Scholar
• Heery, D. M., E. Kalkhoven, S. Hoare, and M. G. Parker. 1997. A signature motif in transcriptional co-activators mediates binding to nuclear receptors. Nature 387:733–736.
   PubMed Web of Science ®Google Scholar
• Heim, R., and R. Y. Tsien. 1996. Engineering green fluorescent protein for improved brightness, longer wavelengths and fluorescence resonance energy transfer. Curr. Biol. 6:178–182.
   PubMed Web of Science ®Google Scholar
• Henttu, P. M. A., E. Kalkhoven, and M. G. Parker. 1997. AF-2 activity and recruitment of steroid receptor coactivator 1 to the estrogen receptor depend on a lysine residue conserved in nuclear receptors. Mol. Cell. Biol. 17:1832–1839.
   PubMedGoogle Scholar
• Htun, H., L. T. Holth, D. Walker, J. R. Davie, and G. L. Hager. 1999. Direct visualization of the human estrogen receptor alpha reveals a role for ligand in the nuclear distribution of the receptor. Mol. Biol. Cell 10:471–486.
   PubMedGoogle Scholar
• Jenster, G., T. E. Spencer, M. M. Burcin, S. Y. Tsai, M. J. Tsai, and B. W. O'Malley. 1997. Steroid receptor induction of gene transcription: a two-step model. Proc. Natl. Acad. Sci. USA 94:7879–7884.
   PubMedGoogle Scholar
• Kamei, Y., L. Xu, T. Heinzel, J. Torchia, R. Kurokawa, B. Gloss, S. C. Lin, R. A. Heyman, D. W. Rose, C. K. Glass, and M. G. Rosenfeld. 1996. A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors. Cell 85:403–414.
   PubMed Web of Science ®Google Scholar
• Kumar, V., S. Green, G. Stack, M. Berry, J. R. Jin, and P. Chambon. 1987. Functional domains of the human estrogen receptor. Cell 51:941–951.
   PubMed Web of Science ®Google Scholar
• Lees, J. A., S. E. Fawell, and M. G. Parker. 1989. Identification of two transactivation domains in the mouse oestrogen receptor. Nucleic Acids Res. 17:5477–5488.
   PubMed Web of Science ®Google Scholar
• Li, G., G. Sudlow, and A. S. Belmont. 1998. Interphase cell cycle dynamics of a late-replicating, heterochromatic homogeneously staining region: precise choreography of condensation/decondensation and nuclear positioning. J. Cell Biol. 140:975–989.
   PubMed Web of Science ®Google Scholar
• Llopis, J., S. Westin, M. Ricote, J. Wang, C. Y. Cho, R. Kurokawa, T. M. Mullen, D. W. Rose, M. G. Rosenfeld, R. Y. Tsien, and C. K. Glass. 2000. Ligand-dependent interactions of coactivators steroid receptor coactivator-1 and peroxisome proliferator-activated receptor binding protein with nuclear hormone receptors can be imaged in live cells and are required for transcription. Proc. Natl. Acad. Sci. USA 97:4363–4368.
   PubMed Web of Science ®Google Scholar
• Mak, H. Y., S. Hoare, P. M. Henttu, and M. G. Parker. 1999. Molecular determinants of the estrogen receptor-coactivator interface. Mol. Cell. Biol. 19:3895–3903.
   PubMedGoogle Scholar
• Mangelsdorf, D. J., C. Thummel, M. Beato, P. Herrlich, G. Schutz, K. Umesono, B. Blumberg, P. Kastner, M. Mark, and P. Chambon. 1995. The nuclear receptor superfamily: the second decade. Cell 83:835–839.
   PubMed Web of Science ®Google Scholar
• McKenna, N. J., R. B. Lanz, and B. W. O'Malley. 1999. Nuclear receptor coregulators: cellular and molecular biology. Endocr. Rev. 20:321–344.
   PubMed Web of Science ®Google Scholar
• McNally, J. G., W. G. Muller, D. Walker, R. Wolford, and G. L. Hager. 2000. The glucocorticoid receptor: rapid exchange with regulatory sites in living cells. Science 287:1262–1265.
   PubMed Web of Science ®Google Scholar
• Nickerson, J. A., B. J. Blencowe, and S. Penman. 1995. The architectural organization of nuclear metabolism. Int. Rev. Cytol. 162A:67–123.
   PubMedGoogle Scholar
• Ogryzko, V. V., R. L. Schiltz, V. Russanova, B. H. Howard, and Y. Nakatani. 1996. The transcriptional coactivators p300 and CBP are histone acetyltransferases. Cell 87:953–959.
   PubMed Web of Science ®Google Scholar
• Onate, S. A., S. Y. Tsai, M. J. Tsai, and B. W. O'Malley. 1995. Sequence and characterization of a coactivator for the steroid hormone receptor superfamily. Science 270:1354–1357.
   PubMed Web of Science ®Google Scholar
• Phair, R. D., and T. Mistelli. 2000. High mobility of proteins in the mammalian cell nucleus. Nature 404:604–609.
   PubMed Web of Science ®Google Scholar
• Robinett, C. C., A. Straight, G. Li, C. Willhelm, G. Sudlow, A. Murray, and A. S. Belmont. 1996. In vivo localization of DNA sequences and visualization of large-scale chromatin organization using lac operator/repressor recognition. J. Cell Biol. 135:1685–1700.
   PubMed Web of Science ®Google Scholar
• Shiau, A. K., D. Barstad, P. M. Loria, L. Cheng, P. J. Kushner, D. A. Agard, and G. L. Greene. 1998. The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen. Cell 95:927–937.
   PubMed Web of Science ®Google Scholar
• Smith, C. L., S. A. Onate, M. J. Tsai, and B. W. O'Malley. 1996. CREB binding protein acts synergistically with steroid receptor coactivator-1 to enhance steroid receptor-dependent transcription. Proc. Natl. Acad. Sci. USA 93:8884–8888.
   PubMed Web of Science ®Google Scholar
• Smith, C. L., and G. L. Hager. 1997. Transcriptional regulation of mammalian genes in vivo. A tale of two templates. J. Biol. Chem. 272:27493–27496.
   PubMed Web of Science ®Google Scholar
• Spencer, T. E., G. Jenster, M. M. Burcin, C. D. Allis, J. Zhou, C. A. Mizzen, N. J. McKenna, S. A. Onate, S. Y. Tsai, M. J. Tsai, and B. W. O'Malley. 1997. Steroid receptor coactivator-1 is a histone acetyltransferase. Nature 389:194–198.
   PubMed Web of Science ®Google Scholar
• Stein, G. S., A. J. van Wijnen, J. L. Stein, J. B. Lian, S. Pockwinse, and S. McNeil. 1998. Interrelationships of nuclear structure and transcriptional control: functional consequences of being in the right place at the right time. J. Cell. Biochem. 70:200–212.
   PubMedGoogle Scholar
• Stenoien, D., Z. D. Sharp, C. L. Smith, and M. A. Mancini. 1998. Functional subnuclear partitioning of transcription factors. J. Cell. Biochem. 70:213–221.
   PubMedGoogle Scholar
• Stenoien, D. L., M. G. Mancini, K. Patel, E. Allegretto, C. L. Smith, and M. A. Mancini. 2000. Subnuclear trafficking of estrogen receptor-α and steroid receptor coactivator-1. Mol. Endocrinol. 14:518–534.
   PubMedGoogle Scholar
• Stenoien, D. L., K. Patel, M. G. Mancini, M. Dutertre, C. L. Smith, B. W. O'Malley, and M. A. Mancini. 2001. FRAP reveals estrogen receptor-α mobility is ligand- and proteasome-dependent. Nat. Cell Biol. 3:15–23.
   PubMed Web of Science ®Google Scholar
• Tora, L., J. White, C. Brou, D. Tasset, N. Webster, E. Scheer, and P. Chambon. 1989. The human estrogen receptor has two independent nonacidic transcriptional activation functions. Cell 59:477–487.
   PubMed Web of Science ®Google Scholar
• Tsai, M. J., and B. W. O'Malley. 1994. Molecular mechanisms of action of steroid/thyroid receptor superfamily members. Annu. Rev. Biochem. 63:451–486.
   PubMed Web of Science ®Google Scholar
• Tumbar, T., G. Sudlow, and A. S. Belmont. 1999. Large-scale chromatin unfolding and remodeling induced by VP16 acidic activation domain. J. Cell Biol. 145:1341–1354.
   PubMed Web of Science ®Google Scholar
• Zhou, G., R. Cummings, Y. Li, S. Mitra, H. A. Wilkinson, A. Elbrecht, J. D. Hermes, J. M. Schaeffer, R. G. Smith, and D. E. Moller. 1998. Nuclear receptors have distinct affinities for coactivators: characterization by fluorescence resonance energy transfer. Mol. Endocrinol. 12:1594–1604.
   PubMedGoogle Scholar