Molecular and Cellular Biology, Volume 21, Issue 13 (2001)

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Molecular and Cellular Biology, Volume 21, Issue 13 (2001)

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Gene Expression

Article
Phosphorylation of the RNA Polymerase II Carboxy-Terminal Domain by the Bur1 Cyclin-Dependent Kinase
Stuart Murray, Rajesh Udupa, Sheng Yao, Grant Hartzog & Gregory Prelich
Pages: 4089-4096
Published online: 28 Mar 2023
AbstractforPhosphorylation of the RNA Polymerase II Carboxy-Terminal Domain by the Bur1 Cyclin-Dependent Kinase | Full Text | References | PDF (212.5 KB)
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Article
Eukaryotic Initiation Factor 4G-Poly(A) Binding Protein Interaction Is Required for Poly(A) Tail-Mediated Stimulation of Picornavirus Internal Ribosome Entry Segment-Driven Translation but Not for X-Mediated Stimulation of Hepatitis C Virus Translation
Yanne M. Michel, Andrew M. Borman, Sylvie Paulous & Katherine M. Kean
Pages: 4097-4109
Published online: 28 Mar 2023
AbstractforEukaryotic Initiation Factor 4G-Poly(A) Binding Protein Interaction Is Required for Poly(A) Tail-Mediated Stimulation of Picornavirus Internal Ribosome Entry Segment-Driven Translation but Not for X-Mediated Stimulation of Hepatitis C Virus Translation | Full Text | References | PDF (693.4 KB)
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Article
Transcriptional Profiling Shows that Gcn4p Is a Master Regulator of Gene Expression during Amino Acid Starvation in Yeast
Krishnamurthy Natarajan, Michael R. Meyer, Belinda M. Jackson, David Slade, Christopher Roberts, Alan G. Hinnebusch & Matthew J. Marton
Pages: 4347-4368
Published online: 28 Mar 2023
AbstractforTranscriptional Profiling Shows that Gcn4p Is a Master Regulator of Gene Expression during Amino Acid Starvation in Yeast | Full Text | References | PDF (2.8 MB)
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Transcriptional Regulation

Article
Pf1, a Novel PHD Zinc Finger Protein That Links the TLE Corepressor to the mSin3A-Histone Deacetylase Complex
Gregory S. Yochum & Donald E. Ayer
Pages: 4110-4118
Published online: 28 Mar 2023
AbstractforPf1, a Novel PHD Zinc Finger Protein That Links the TLE Corepressor to the mSin3A-Histone Deacetylase Complex | Full Text | References | PDF (358.7 KB)
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Article
TFIIS Enhances Transcriptional Elongation through an Artificial Arrest Site In Vivo
Dmitry Kulish & Kevin Struhl
Pages: 4162-4168
Published online: 28 Mar 2023
AbstractforTFIIS Enhances Transcriptional Elongation through an Artificial Arrest Site In Vivo | Full Text | References | PDF (191.1 KB)
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Article
Functional Characterization of Interferon Regulatory Factor 3a (IRF-3a), an Alternative Splice Isoform of IRF-3
Alla Y. Karpova, Lucienne V. Ronco & Peter M. Howley
Pages: 4169-4176
Published online: 28 Mar 2023
AbstractforFunctional Characterization of Interferon Regulatory Factor 3a (IRF-3a), an Alternative Splice Isoform of IRF-3 | Full Text | References | PDF (260.7 KB)
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Article
Essential Roles of Snf5p in Snf-Swi Chromatin Remodeling In Vivo
Fuqiang Geng, Yixue Cao & Brehon C. Laurent
Pages: 4311-4320
Published online: 28 Mar 2023
AbstractforEssential Roles of Snf5p in Snf-Swi Chromatin Remodeling In Vivo | Full Text | References | PDF (370.6 KB)
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Article
Use of Suppressor Mutants To Probe the Function of Estrogen Receptor-p160 Coactivator Interactions
Ho Yi Mak & Malcolm G. Parker
Pages: 4379-4390
Published online: 28 Mar 2023
AbstractforUse of Suppressor Mutants To Probe the Function of Estrogen Receptor-p160 Coactivator Interactions | Full Text | References | PDF (616.5 KB)
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Article
Ligand-Mediated Assembly and Real-Time Cellular Dynamics of Estrogen Receptor α-Coactivator Complexes in Living Cells
David L. Stenoien, Anne C. Nye, Maureen G. Mancini, Kavita Patel, Martin Dutertre, Bert W. O'Malley, Carolyn L. Smith, Andrew S. Belmont & Michael A. Mancini
Pages: 4404-4412
Published online: 28 Mar 2023
AbstractforLigand-Mediated Assembly and Real-Time Cellular Dynamics of Estrogen Receptor α-Coactivator Complexes in Living Cells | Full Text | References | PDF (507.9 KB)
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Mammalian Genetic Models With Minimal Or Complex Phenotypes

Article
Loss of Annexin A7 Leads to Alterations in Frequency-Induced Shortening of Isolated Murine Cardiomyocytes
Claudia Herr, Neil Smyth, Susanne Ullrich, Fan Yun, Phillip Sasse, Jürgen Hescheler, Bernd Fleischmann, Katrin Lasek, Klara Brixius, Robert H. G. Schwinger, Reinhard Fässler, Rolf Schröder & Angelika A. Noegel
Pages: 4119-4128
Published online: 28 Mar 2023
AbstractforLoss of Annexin A7 Leads to Alterations in Frequency-Induced Shortening of Isolated Murine Cardiomyocytes | Full Text | References | PDF (313.3 KB)
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Article
Impaired Activity of the Extraneuronal Monoamine Transporter System Known as Uptake-2 in Orct3/Slc22a3-Deficient Mice
Ronald Zwart, Sandra Verhaagh, Marije Buitelaar, Corrie Popp-Snijders & Denise P. Barlow
Pages: 4188-4196
Published online: 28 Mar 2023
AbstractforImpaired Activity of the Extraneuronal Monoamine Transporter System Known as Uptake-2 in Orct3/Slc22a3-Deficient Mice | Full Text | References | PDF (309.5 KB)
  • 63 Views
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Article
The Polycomb-Group GeneEzh2 Is Required for Early Mouse Development
Dónal O'Carroll, Sylvia Erhardt, Michaela Pagani, Sheila C. Barton, M. Azim Surani & Thomas Jenuwein
Pages: 4330-4336
Published online: 28 Mar 2023
AbstractforThe Polycomb-Group GeneEzh2 Is Required for Early Mouse Development | Full Text | References | PDF (927.7 KB)
  • 233 Views
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Article
Nkx2.5 and Nkx2.6, Homologs of Drosophila tinman, Are Required for Development of the Pharynx
Makoto Tanaka, Martina Schinke, Hai-Sun Liao, Naohito Yamasaki & Seigo Izumo
Pages: 4391-4398
Published online: 28 Mar 2023
AbstractforNkx2.5 and Nkx2.6, Homologs of Drosophila tinman, Are Required for Development of the Pharynx | Full Text | References | PDF (3.6 MB)
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Article
Mice Lacking the Nkx6.2 (Gtx) Homeodomain Transcription Factor Develop and Reproduce Normally
Jun Cai, Yingchuan Qi, Rui Wu, Geoffrey Modderman, Hui Fu, Rugao Liu & Mengsheng Qiu
Pages: 4399-4403
Published online: 28 Mar 2023
AbstractforMice Lacking the Nkx6.2 (Gtx) Homeodomain Transcription Factor Develop and Reproduce Normally | Full Text | References | PDF (631.6 KB)
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Cell Growth and Development

Article
ATR-Mediated Checkpoint Pathways Regulate Phosphorylation and Activation of Human Chk1
Hui Zhao & Helen Piwnica-Worms
Pages: 4129-4139
Published online: 28 Mar 2023
AbstractforATR-Mediated Checkpoint Pathways Regulate Phosphorylation and Activation of Human Chk1 | Full Text | References | PDF (317.4 KB)
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Article
Early Cell Cycle Box-Mediated Transcription ofCLN3 and SWI4 Contributes to the Proper Timing of the G1-to-S Transition in Budding Yeast
Vivian L. MacKay, Bernard Mai, Laurie Waters & Linda L. Breeden
Pages: 4140-4148
Published online: 28 Mar 2023
AbstractforEarly Cell Cycle Box-Mediated Transcription ofCLN3 and SWI4 Contributes to the Proper Timing of the G1-to-S Transition in Budding Yeast | Full Text | References | PDF (351 KB)
  • 5 Views
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Article
Docking Protein FRS2 Links the Protein Tyrosine Kinase RET and Its Oncogenic Forms with the Mitogen-Activated Protein Kinase Signaling Cascade
R. M. Melillo, M. Santoro, S.-H. Ong, M. Billaud, A. Fusco, Y. R. Hadari, J. Schlessinger & I. Lax
Pages: 4177-4187
Published online: 28 Mar 2023
AbstractforDocking Protein FRS2 Links the Protein Tyrosine Kinase RET and Its Oncogenic Forms with the Mitogen-Activated Protein Kinase Signaling Cascade | Full Text | References | PDF (328.3 KB)
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Article
Intrasteric Inhibition of ATP Binding Is Not Required To Prevent Unregulated Autophosphorylation or Signaling by the Insulin Receptor
Mark Frankel, Ararat J. Ablooglu, Joseph W. Leone, Elena Rusinova, J. B. Alexander Ross, Robert L. Heinrikson & Ronald A. Kohanski
Pages: 4197-4207
Published online: 28 Mar 2023
AbstractforIntrasteric Inhibition of ATP Binding Is Not Required To Prevent Unregulated Autophosphorylation or Signaling by the Insulin Receptor | Full Text | References | PDF (234 KB)
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Article
Identification of a Phospholipase C-γ1 (PLC-γ1) SH3 Domain-Binding Site in SLP-76 Required for T-Cell Receptor-Mediated Activation of PLC-γ1 and NFAT
Deborah Yablonski, Theresa Kadlecek & Arthur Weiss
Pages: 4208-4218
Published online: 28 Mar 2023
AbstractforIdentification of a Phospholipase C-γ1 (PLC-γ1) SH3 Domain-Binding Site in SLP-76 Required for T-Cell Receptor-Mediated Activation of PLC-γ1 and NFAT | Full Text | References | PDF (335.3 KB)
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Article
Evidence of p53-Dependent Cross-Talk between Ribosome Biogenesis and the Cell Cycle: Effects of Nucleolar Protein Bop1 on G1/S Transition
Dimitri G. Pestov, Žaklina Strezoska & Lester F. Lau
Pages: 4246-4255
Published online: 28 Mar 2023
AbstractforEvidence of p53-Dependent Cross-Talk between Ribosome Biogenesis and the Cell Cycle: Effects of Nucleolar Protein Bop1 on G1/S Transition | Full Text | References | PDF (394 KB)
  • 83 Views
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Article
HER4 Mediates Ligand-Dependent Antiproliferative and Differentiation Responses in Human Breast Cancer Cells
Carolyn I. Sartor, Hong Zhou, Ewa Kozlowska, Katherine Guttridge, Evelyn Kawata, Laura Caskey, Jennifer Harrelson, Nancy Hynes, Stephen Ethier, Benjamin Calvo & H. Shelton Earp III
Pages: 4265-4275
Published online: 28 Mar 2023
AbstractforHER4 Mediates Ligand-Dependent Antiproliferative and Differentiation Responses in Human Breast Cancer Cells | Full Text | References | PDF (490.7 KB)
  • 20 Views
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Article
Molecular Cloning of ILP-2, a Novel Member of the Inhibitor of Apoptosis Protein Family
Bettina W. M. Richter, Samy S. Mir, Lisa J. Eiben, Jennifer Lewis, Stephanie Birkey Reffey, Annalisa Frattini, Lan Tian, Stephan Frank, Richard J. Youle, David L. Nelson, Luigi D. Notarangelo, Paolo Vezzoni, Howard O. Fearnhead & Colin S. Duckett
Pages: 4292-4301
Published online: 28 Mar 2023
AbstractforMolecular Cloning of ILP-2, a Novel Member of the Inhibitor of Apoptosis Protein Family | Full Text | References | PDF (399.7 KB)
  • 19 Views
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Article
A Human Protein with Sequence Similarity to Drosophila Mastermind Coordinates the Nuclear Form of Notch and a CSL Protein To Build a Transcriptional Activator Complex on Target Promoters
Motoo Kitagawa, Toshinao Oyama, Taichi Kawashima, Barry Yedvobnick, Anumeha Kumar, Kenji Matsuno & Kenichi Harigaya
Pages: 4337-4346
Published online: 28 Mar 2023
AbstractforA Human Protein with Sequence Similarity to Drosophila Mastermind Coordinates the Nuclear Form of Notch and a CSL Protein To Build a Transcriptional Activator Complex on Target Promoters | Full Text | References | PDF (1.2 MB)
  • 36 Views
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Article
Complex Functions of AP-1 Transcription Factors in Differentiation and Survival of PC12 Cells
Sirpa Leppä, Minna Eriksson, Rainer Saffrich, Wilhelm Ansorge & Dirk Bohmann
Pages: 4369-4378
Published online: 28 Mar 2023
AbstractforComplex Functions of AP-1 Transcription Factors in Differentiation and Survival of PC12 Cells | Full Text | References | PDF (6.6 MB)
  • 35 Views
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Dna Dynamics and Chromosome Structure

Article
Establishment of an oriP Replicon Is Dependent upon an Infrequent, Epigenetic Event
Elizabeth R. Leight & Bill Sugden
Pages: 4149-4161
Published online: 28 Mar 2023
AbstractforEstablishment of an oriP Replicon Is Dependent upon an Infrequent, Epigenetic Event | Full Text | References | PDF (508.4 KB)
  • 12 Views
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Article
New Function of CDC13 in Positive Telomere Length Regulation
Bettina Meier, Lucia Driller, Sigrun Jaklin & Heidi M. Feldmann
Pages: 4233-4245
Published online: 28 Mar 2023
AbstractforNew Function of CDC13 in Positive Telomere Length Regulation | Full Text | References | PDF (594.6 KB)
  • 9 Views
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Article
Functional Organization of Single and Paired V(D)J Cleavage Complexes
Mark A. Landree, Sam B. Kale & David B. Roth
Pages: 4256-4264
Published online: 28 Mar 2023
AbstractforFunctional Organization of Single and Paired V(D)J Cleavage Complexes | Full Text | References | PDF (417.6 KB)
  • 4 Views
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Article
RAG Transposase Can Capture and Commit to Target DNA before or after Donor Cleavage
Matthew B. Neiditch, Gregory S. Lee, Mark A. Landree & David B. Roth
Pages: 4302-4310
Published online: 28 Mar 2023
AbstractforRAG Transposase Can Capture and Commit to Target DNA before or after Donor Cleavage | Full Text | References | PDF (383.4 KB)
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Nucleocytoplasmic Communication

Article
The Yeast hnRNP-Like Proteins Yra1p and Yra2p Participate in mRNA Export through Interaction with Mex67p
Daniel Zenklusen, Patrizia Vinciguerra, Yvan Strahm & Françoise Stutz
Pages: 4219-4232
Published online: 28 Mar 2023
AbstractforThe Yeast hnRNP-Like Proteins Yra1p and Yra2p Participate in mRNA Export through Interaction with Mex67p | Full Text | References | PDF (552.2 KB)
  • 49 Views
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Cell and Organelle Structure and Assembly

Article
In Vivo Action of the HRD Ubiquitin Ligase Complex: Mechanisms of Endoplasmic Reticulum Quality Control and Sterol Regulation
Richard G. Gardner, Alexander G. Shearer & Randolph Y. Hampton
Pages: 4276-4291
Published online: 28 Mar 2023
AbstractforIn Vivo Action of the HRD Ubiquitin Ligase Complex: Mechanisms of Endoplasmic Reticulum Quality Control and Sterol Regulation | Full Text | References | PDF (838.1 KB)
  • 28 Views
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Article
Identification of a Peroxisomal ATP Carrier Required for Medium-Chain Fatty Acid β-Oxidation and Normal Peroxisome Proliferation in Saccharomyces cerevisiae
Carlo W. T. van Roermund, Roy Drissen, Marlene van den Berg, Lodewijk Ijlst, Ewald H. Hettema, Henk F. Tabak, Hans R. Waterham & Ronald J. A. Wanders
Pages: 4321-4329
Published online: 28 Mar 2023
AbstractforIdentification of a Peroxisomal ATP Carrier Required for Medium-Chain Fatty Acid β-Oxidation and Normal Peroxisome Proliferation in Saccharomyces cerevisiae | Full Text | References | PDF (207.8 KB)
  • 33 Views
  • 78 CrossRef citations
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Article
Human Pex19p Binds Peroxisomal Integral Membrane Proteins at Regions Distinct from Their Sorting Sequences
Marc Fransen, Tine Wylin, Chantal Brees, Guy P. Mannaerts & Paul P. Van Veldhoven
Pages: 4413-4424
Published online: 28 Mar 2023
AbstractforHuman Pex19p Binds Peroxisomal Integral Membrane Proteins at Regions Distinct from Their Sorting Sequences | Full Text | References | PDF (2.7 MB)
  • 44 Views
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Author's Correction

Correction
Threonine-11, Phosphorylated by Rad3 and ATM In Vitro, Is Required for Activation of Fission Yeast Checkpoint Kinase Cds1
Page: 4425
Published online: 28 Mar 2023
CitationforThreonine-11, Phosphorylated by Rad3 and ATM In Vitro, Is Required for Activation of Fission Yeast Checkpoint Kinase Cds1 | Full Text | PDF (15.1 KB)
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