25
Views
50
CrossRef citations to date
0
Altmetric
Transcriptional Regulation

New Model for the Yeast RNA Polymerase I Transcription Cycle

, &
Pages 4847-4855 | Received 03 Apr 2001, Accepted 07 May 2001, Published online: 28 Mar 2023

REFERENCES

  • Albert, A. C., M. Denton, M. Kermekchiev, and C. S. Pikaard. 1999. Histone acetyltransferase and protein kinase activities copurify with a putative Xenopus RNA polymerase I holoenzyme self-sufficient for promoter-dependent transcription. Mol. Cell. Biol. 19:796–806.
  • Aprikian, P., B. Moorefield, C.-W. Lin, and R. H. Reeder. 2000. TATA binding protein can stimulate core-directed transcription by yeast RNA polymerase I. Mol. Cell. Biol. 20:5269–5275.
  • Bodem, J., G. Dobreva, U. Hoffmann-Rohrer, S. Iben, H. Zentgraf, H. Delius, M. Vingron, and I. Grummt. 2000. TIF-IA, the factor mediating growth-dependent control of ribosomal RNA synthesis, is the mammalian homolog of yeast Rrn3p. EMBO Rep. 1:171–175.
  • Bordi, L., F. Cioci, and G. Camilloni. 2001. In vivo binding and hierarchy of assembly of the yeast RNA polymerase I transcription factors. Mol. Biol. Cell 12:753–760.
  • Carles, C., and M. Riva. 1998. Yeast RNA polymerase I subunits and genes. Transcription of ribosomal RNA genes by eukaryotic RNA polymerase.. I. Paule Springer Verlag, Berlin, Germany
  • Cormack, B. P., and K. Struhl. 1992. The TATA-binding protein is required for transcription by all three nuclear RNA polymerases in yeast cells. Cell 69:685–696.
  • Dammann, R., R. Lucchini, T. Koller, and J. M. Sogo. 1993. Chromatin structures and transcription of rDNA in yeast Saccharomyces cerevisiae. Nucleic Acids Res. 21:2331–2338.
  • Elion, E., and J. R. Warner. 1986. An RNA polymerase I enhancer in Saccharomyces cerevisiae. Mol. Cell. Biol. 6:2089–2097.
  • Goldmark, J. P., T. G. Fazzio, P. W. Estep, G. M. Church, and T. Tsukiyama. 2000. The Isw2 chromatin remodeling complex represses early meiotic genes upon recruitment by Ume6p. Cell 103:423–433.
  • Hannan, R. D., A. Cavanaugh, W. M. Hempel, T. Moss, and L. Rothblum. 1999. Identification of a mammalian RNA polymerase I holoenzyme containing components of the DNA repair/replication system. Nucleic Acids Res. 27:3720–3727.
  • Ishihama, A., M. Kimura, and H. Mitsuzawa. 1998. Subunits of yeast RNA polymerases: structure and function. Curr. Opin. Microbiol. 1:190–196.
  • Kassavetis, G. A., A. Kumar, G. A. Letts, and E. P. Geiduschek. 1998. A post-recruitment function for the RNA polymerase III transcription-initiation factor IIIB. Proc. Natl. Acad. Sci. USA 95:9196–9201.
  • Keener, J., J. A. Dodd, D. Lalo, and M. Nomura. 1997. Histones H3 and H4 are components of upstream activation factor required for the high-level transcription of yeast rDNA by RNA polymerase I. Proc. Natl. Acad. Sci. USA 94:13458–13462.
  • Keener, J., C. A. Josaitis, J. A. Dodd, and M. Nomura. 1998. Reconstitution of yeast RNA polymerase I transcription in vitro from purified components. J. Biol. Chem. 173:33795–33802.
  • Keys, D. A., B.-S. Lee, J. A. Dodd, T. T. Nguyen, L. Vu, E. Fantino, L. M. Burson, Y. Nogi, and M. Nomura. 1996. Multiprotein transcription factor UAF interacts with the upstream element of the yeast RNA polymerase I promoter and forms a stable preinitiation complex. Genes Dev. 10:887–903.
  • Keys, D. A., J. S. Steffan, J. A. Dodd, R. T. Yamamoto, Y. Nogi, and M. Nomura. 1994. RRN6 and RRN7 encode subunits of a multiprotein complex essential for the initiation of rDNA transcription by RNA polymerase I in Saccharomyces cerevisiae. Genes Dev. 8:2349–2362.
  • Lalo, D., J. S. Steffan, J. A. Dodd, and M. Nomura. 1996. RRN11 encodes the third subunit of the complex containing Rrn6p and Rrn7p that is essential for the initiation of rDNA transcription by yeast RNA polymerase I. J. Biol. Chem. 271:21062–21067.
  • Lin, C.-W., B. Moorefield, J. Payne, P. Aprikian, K. Mitomo, and R. H. Reeder. 1996. A novel 66-kilodalton protein complexes with Rrn6, Rrn7, and TATA-binding protein to promote polymerase I transcription initiation in Saccharomyces cerevisiae. Mol. Cell. Biol. 16:6436–6443.
  • Milkereit, P., and H. Tschochner. 1998. A specialized form of RNA polymerase I, essential for initiation and growth-dependent regulation of rRNA synthesis, is disrupted during transcription. EMBO J. 17:3692–3703.
  • Miller, G., K. I. Panov, J. K. Friedrich, L. Trinkle-Mulcahy, and J. C. B. M. Zomerdijk. 2001. hRRN3 is essential in the SL1-mediated recruitment of RNA polymerase I to rRNA gene promoters. EMBO J. 20:1373–1382.
  • Moorefield, B., E. A. Greene, and R. H. Reeder. 2000. RNA polymerase I transcription factor Rrn3 is functionally conserved between yeast and human. Proc. Natl. Acad. Sci. USA 97:4724–4729.
  • Myer, V. E., and R. A. Young. 1998. RNA polymerase II holoenzymes and subcomplexes. J. Biol. Chem. 273:27757–27760.
  • Nogi, Y., R. Yano, and M. Nomura. 1991. Synthesis of large rRNAs by RNA polymerase II in mutants of Saccharomyces cerevisiae defective in RNA polymerase I. Proc. Natl. Acad. Sci. USA 88:3962–3966.
  • Orphanides, G., T. Lagrange, and D. Reinberg. 1996. General initiation factors of RNA polymerase II. Genes Dev. 10:2657–2683.
  • Peyroche, G., P. Milkereit, N. Bischler, H. Tschochner, P. Schultz, A. Sentenac, C. Carles, and M. Riva. 2000. The recruitment of RNA polymerase I on rDNA is mediated by the interaction of the A43 subunit with Rrn3. EMBO J. 19:5473–5482.
  • Ranish, J. A., N. Yudkovsky, and S. Hahn. 1999. Intermediates in formation and activity of the RNA polymerase II preinitiation complex: holoenzyme recruitment and a postrecruitment role for the TATA box and TFIIB. Genes Dev. 13:49–63.
  • Reeder, R. H.. 1989. Regulatory elements of the generic ribosomal gene. Curr. Opin. Cell Biol. 1:466–474.
  • Reeder, R. H.. 1992. The regulation of transcription by RNA polymerase I. Transcriptional regulation.. K. Yamamoto, and S. McKnight Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y
  • SaezVasquez, J., and C. S. Pikaard. 1997. Extensive purification of a putative RNA polymerase I holoenzyme from plants that accurately initiates rRNA gene transcription in vitro. Proc. Natl. Acad. Sci. USA 94:11869–11874.
  • Schnapp, A., and I. Grummt. 1991. Transcription complex formation at the mouse rDNA promoter involves the stepwise association of four transcription factors and RNA polymerase I. J. Biol. Chem. 266:24588–24595.
  • Schnapp, A., G. Schnapp, B. Erny, and I. Grummt. 1993. Function of the growth-regulated transcription initiation factor TIF-IA in initiation complex formation at the murine ribosomal gene promoter. Mol. Cell. Biol. 13:6723–6732.
  • Schultz, M. C., R. H. Reeder, and S. Hahn. 1992. Variants of the TATA binding protein can distinguish subsets of RNA polymerase I, II, and III promoters. Cell 69:697–702.
  • Seither, P., S. Iben, and I. Grummt. 1998. Mammalian RNA polymerase I exists as a holoenzyme with associated basal transcription factors. J. Mol. Biol. 275:43–53.
  • Steffan, J. S., D. A. Keys, J. A. Dodd, and M. Nomura. 1996. The role of TBP in rDNA transcription by RNA polymerase I in Saccharomyces cerevisiae: TBP is required for upstream activation factor-dependent recruitment of core factor. Genes Dev. 10:2551–2563.
  • Steffan, J. S., D. A. Keys, L. Vu, and M. Nomura. 1998. Interaction of TATA-binding protein with upstream activation factor is required for activated transcription of ribosomal DNA by RNA polymerase I in Saccharomyces cerevisiae in vivo. Mol. Cell. Biol. 18:3752–3761.
  • Vogelauer, M., F. Cioci, and G. Camilloni. 1998. DNA protein-interactions at the Saccharomyces cerevisiae 35S rRNA promoter and in its surrounding region. J. Mol. Biol. 275:197–209.
  • Yamamoto, R. T., Y. Nogi, J. A. Dodd, and M. Nomura. 1996. RRN3 gene of Saccharomyces cerevisiae encodes an essential RNA polymerase I transcription factor which interacts with the polymerase independently of DNA template. EMBO J. 15:3964–3973.
  • Yudkovsky, N., C. Logie, S. Hahn, and C. L. Peterson. 1999. Recruitment of the SWI/SNF chromatin remodeling complex by transcriptional activators. Genes Dev. 13:2369–2374.
  • Yudkovsky, N., J. A. Ranish, and S. Hahn. 2000. A transcription reinitiation intermediate that is stabilized by activator. Nature 408:225–229.
  • Zhao, X., E. G. Muller, and R. Rothstein. 1998. A suppressor of two essential checkpoint genes identified a novel protein that negatively affects dNTP pools. Mol. Cell 2:329–340.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.