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Cell Growth and Development

Control of Cyclin-Dependent Kinase Inhibitor p27 Expression by Cap-Independent Translation

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Pages 4960-4967 | Received 14 Aug 2000, Accepted 03 May 2001, Published online: 28 Mar 2023

REFERENCES

  • Agrawal, D., P. Hauser, F. McPherson, F. Dong, A. Garcia, and W. J. Pledger. 1996. Repression of p27kip1 synthesis by platelet-derived growth factor in BALB/c 3T3 cells. Mol. Cell. Biol. 16:4327–4336.
  • Beretta, L., A. C. Gingras, Y. V. Svitkin, M. N. Hall, and N. Sonenberg. 1996. Rapamycin blocks the phosphorylation of 4E-BP1 and inhibits cap-dependent initiation of translation. EMBO J. 15:658–664.
  • Clurman, B. E., and P. Porter. 1998. New insights into the tumor suppression function of P27(kip1). Proc. Natl. Acad. Sci. USA 95:15158–15160.
  • Dahia, P. L., R. C. Aguiar, J. Honegger, R. Fahlbush, S. Jordan, D. G. Lowe, X. Lu, R. N. Clayton, G. M. Besser, and A. B. Grossman. 1998. Mutation and expression analysis of the p27/kip1 gene in corticotrophin-secreting tumours. Oncogene 16:69–76.
  • De Benedetti, A., and A. L. Harris. 1999. eIF4E expression in tumors: its possible role in progression of malignancies. Int. J. Biochem. Cell Biol. 31:59–72.
  • Duncan, R., S. C. Milburn, and J. W. Hershey. 1987. Regulated phosphorylation and low abundance of HeLa cell initiation factor eIF-4F suggest a role in translational control. Heat shock effects on eIF-4F. J. Biol. Chem. 262:380–388.
  • Ferrando, A. A., M. Balbin, A. M. Pendas, F. Vizoso, G. Velasco, and C. Lopez-Otin. 1996. Mutational analysis of the human cyclin-dependent kinase inhibitor p27kip1 in primary breast carcinomas. Hum. Genet. 97:91–94.
  • Gan, W., M. L. Celle, and R. E. Rhoads. 1998. Functional characterization of the internal ribosome entry site of eIF4G mRNA. J. Biol. Chem. 276:5006–5012.
  • Haghighat, A., S. Mader, A. Pause, and N. Sonenberg. 1995. Repression of cap-dependent translation by 4E-binding protein 1: competition with p220 for binding to eukaryotic initiation factor-4E. EMBO J. 14:5701–5709.
  • Hengst, L., and S. I. Reed. 1996. Translational control of p27Kip1 accumulation during the cell cycle. Science 271:1861–1864.
  • Houdebine, L. M., and J. Attal. 1999. Internal ribosome entry sites (IRESs): reality and use. Transgenic Res. 8:157–177.
  • Hunt, S. L., J. J. Hsuan, N. Totty, and R. J. Jackson. 1999. unr, a cellular cytoplasmic RNA-binding protein with five cold-shock domains, is required for internal initiation of translation of human rhinovirus RNA. Genes Dev. 13:437–448.
  • Jones, R. M., J. Branda, K. A. Johnston, M. Polymenis, M. Gadd, A. Rustgi, L. Callanan, and E. V. Schmidt. 1996. An essential E box in the promoter of the gene encoding the mRNA cap-binding protein (eukaryotic initiation factor 4E) is a target for activation by c-myc. Mol. Cell. Biol. 16:4754–4764.
  • Kawamata, N., R. Morosetti, C. W. Miller, D. Park, K. S. Spirin, T. Nakamaki, S. Takeuchi, Y. Hatta, J. Simpson, and S. Wilcyznski. 1995. Molecular analysis of the cyclin-dependent kinase inhibitor gene p27/Kip1 in human malignancies. Cancer Res. 55:2266–2269.
  • Kerekatte, V., K. Smiley, B. Hu, A. Smith, F. Gelder, and A. De Benedetti. 1995. The proto-oncogene/translation factor eIF4E: a survey of its expression in breast carcinomas. Int. J. Cancer 64:27–31.
  • Kozak, M.. 1989. Circumstances and mechanisms of inhibition of translation by secondary structure in eucaryotic mRNAs. Mol. Cell. Biol. 9:5134–5142.
  • Kwon, T. K., J. E. Nagel, M. A. Buchholz, and A. A. Nordin. 1996. Characterization of the murine cyclin-dependent kinase inhibitor gene p27Kip1. Gene 180:113–120.
  • Lazaris-Karatzas, A., and N. Sonenberg. 1992. The mRNA 5′ cap-binding protein, eIF-4E, cooperates with v-Myc or E1A in the transformation of primary rodent fibroblasts. Mol. Cell. Biol. 12:1234–1238.
  • Li, B. D., L. Liu, M. Dawson, and A. De Benedetti. 1997. Overexpression of eukaryotic initiation factor 4E (eIF4E) in breast carcinoma. Cancer 79:2385–2390.
  • Lloyd, R. V., L. A. Erickson, L. Jin, E. Kulig, X. Qian, J. C. Cheville, and B. W. Scheithauer. 1999. p27kip1: a multifunctional cyclin-dependent kinase inhibitor with prognostic significance in human cancers. Am. J. Pathol. 154:313–323.
  • Macejak, D. G., and P. Sarnow. 1991. Internal initiation of translation mediated by the 5′ leader of a cellular mRNA. Nature 353:90–94.
  • Mader, S., H. Lee, A. Pause, and N. Sonenberg. 1995. The translation initiation factor eIF-4E binds to a common motif shared by the translation factor eIF-4 gamma and the translational repressors 4E-binding proteins. Mol. Cell. Biol. 15:4990–4997.
  • McKendrick, L., V. M. Pain, and S. J. Morley. 1999. Translation initiation factor 4E. Int. J. Biochem. Cell Biol. 31:31–35.
  • Millard, S. S., A. Vidal, M. Markus, and A. Koff. 2000. A U-rich element in the 5′ untranslated region is necessary for the translation of p27 mRNA. Mol. Cell. Biol. 20:5947–5959.
  • Millard, S. S., J. S. Yan, H. Nguyen, M. Pagano, H. Kiyokawa, and A. Koff. 1997. Enhanced ribosomal association of p27(Kip1) mRNA is a mechanism contributing to accumulation during growth arrest. J. Biol. Chem. 272:7093–7098.
  • Miyagi, Y., A. Sugiyama, A. Asai, T. Okazaki, Y. Kuchino, and S. J. Kerr. 1995. Elevated levels of eukaryotic translation initiation factor eIF-4E, mRNA in a broad spectrum of transformed cell lines. Cancer Lett. 91:247–252.
  • Mothe-Satney, I., D. Yang, P. Fadden, T. A. Haystead, and J. C. Lawrence Jr.. 2000. Multiple mechanisms control phosphorylation of PHAS-I in five (S/T)P sites that govern translational repression. Mol. Cell. Biol. 20:3558–3567.
  • Nathan, C. A., S. Franklin, F. W. Abreo, R. Nassar, A. De Benedetti, J. Williams, and F. J. Stucker. 1999. Expression of eIF4E during head and neck tumorigenesis: possible role in angiogenesis. Laryngoscope 109:1253–1258.
  • Ouyang, Q., M. Bommakanti, and W. K. Miskimins. 1993. A mitogen-responsive promoter region that is synergistically activated through multiple signalling pathways. Mol. Cell. Biol. 13:1796–1804.
  • Pagano, M., S. W. Tam, A. M. Theodoras, P. Beer-Romero, G. Del Sal, V. Chau, P. R. Yew, G. F. Draetta, and M. Rolfe. 1995. Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27. Science 269:682–685.
  • Pelletier, J., and N. Sonenberg. 1988. Internal initiation of translation of eukaryotic mRNA directed by a sequence derived from poliovirus RNA. Nature 334:320–325.
  • Ponce-Castaneda, M. V., M. H. Lee, E. Latres, K. Polyak, L. Lacombe, K. Montgomery, S. Mathew, K. Krauter, J. Sheinfeld, and J. Massague. 1995. p27Kip1: chromosomal mapping to 12p12–12p13.1 and absence of mutations in human tumors. Cancer Res. 55:1211–1214.
  • Pyronnet, S., L. Pradayrol, and N. Sonenberg. 2000. A cell cycle-dependent internal ribosome entry site. Mol. Cell 5:607–616.
  • Rhoads, R. E.. 1999. Signal transduction pathways that regulate eukaryotic protein synthesis. J. Biol. Chem. 274:30337–30340.
  • Sachs, A. B., P. Sarnow, and M. W. Hentze. 1997. Starting at the beginning, middle, and end: translation initiation in eukaryotes. Cell 89:831–838.
  • Sella, O., G. Gerlitz, S. Y. Le, and O. Elroy-Stein. 1999. Differentiation-induced internal translation of c-sis mRNA: analysis of the cis elements and their differentiation-linked binding to the hnRNP C protein. Mol. Cell. Biol. 19:5429–5240.
  • Sizova, D. V., V. G. Kolupaeva, T. V. Pestova, I. N. Shatsky, and C. U. Hellen. 1998. Specific interaction of eukaryotic translation initiation factor 3 with the 5′ nontranslated regions of hepatitis C virus and classical swine fever virus RNAs. J. Virol. 72:4775–4782.
  • Smith, M. R., M. Jaramillo, Y. L. Liu, T. E. Dever, W. C. Merrick, H. F. Kung, and N. Sonenberg. 1990. Translation initiation factors induce DNA synthesis and transform NIH 3T3 cells. New Biol. 2:648–654.
  • Toyoshima, H., and T. Hunter. 1994. p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21. Cell 78:67–74.
  • Waskiewicz, A. J., J. C. Johnson, B. Penn, M. Mahalingam, S. R. Kimball, and J. A. Cooper. 1999. Phosphorylation of the cap-binding protein eukaryotic translation initiation factor 4E by protein kinase Mnk1 in vivo. Mol. Cell. Biol. 19:1871–1880.
  • Zhang, Y., and S. C. Lin. 1997. Molecular characterization of the cyclin-dependent kinase inhibitor p27 promoter. Biochim. Biophys. Acta 1353:307–317.
  • Zhao, Z., F. C. Chang, and H. M. Furneaux. 2000. The identification of an endonuclease that cleaves within an HuR binding site in mRNA. Nucleic Acids Res. 28:2695–2701.

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