Stimulation of DNA Replication from the Polyomavirus Origin by PCAF and GCN5 Acetyltransferases: Acetylation of Large T Antigen

REFERENCES

• Alexiadis, V., L. Halmer, and C. Gruss. 1997. Influence of core histone acetylation on SV40 minichromosome replication in vitro. Chromosoma 105: 324–331.
   PubMedGoogle Scholar
• Arany, Z., W. R. Sellers, D. M. Livingston, and R. Eckner. 1994. E1A-associated p300 and CREB-associated CBP belong to a conserved family of coactivators. Cell 77: 799–800.
   PubMed Web of Science ®Google Scholar
• Archer, T. K., P. Lefebvre, R. G. Wolford, and G. L. Hager. 1992. Transcription factor loading on the MMTV promoter: a bimodal mechanism for promoter activation. Science 255: 1573–1576.
   PubMed Web of Science ®Google Scholar
• Arias, J., A. S. Alberts, P. Brindle, F. X. Claret, T. Smeal, M. Karin, J. Feramisco, and M. Montminy. 1994. Activation of cAMP and mitogen responsive genes relies on a common nuclear factor. Nature 370: 226–229.
   PubMed Web of Science ®Google Scholar
• Avantaggiati, M. L., V. Ogryzko, K. Gardner, A. Giordano, A. S. Levine, and K. Kelly. 1997. Recruitment of p300/CBP in p53-dependent signal pathways. Cell 89: 1175–1184.
   PubMed Web of Science ®Google Scholar
• Bannister, A. J., T. Oehler, D. Wilhelm, P. Angel, and T. Kouzarides. 1995. Stimulation of c-Jun activity by CBP: c-Jun residues Ser63/73 are required for CBP induced stimulation in vivo and CBP binding in vitro. Oncogene 11: 2509–2514.
   PubMed Web of Science ®Google Scholar
• Bannister, A. J., and T. Kouzarides. 1995. CBP-induced stimulation of c-Fos activity is abrogated by E1A. EMBO J. 14: 4758–4762.
   PubMed Web of Science ®Google Scholar
• Baru, M., M. Shlissel, and H. Manor. 1991. The yeast GAL4 protein transactivates the polyomavirus origin of DNA replication in mouse cells. J. Virol. 65: 3496–3503.
   PubMedGoogle Scholar
• Baumann, M., R. Feederle, E. Kremmer, and W. Hammerschmidt. 1999. Cellular transcription factors recruit viral replication proteins to activate the Epstein-Barr virus origin of lytic DNA replication, oriLyt. EMBO J. 18: 6095–6105.
   PubMedGoogle Scholar
• Bennett, E. R., M. Naujokas, and J. A. Hassell. 1989. Requirements for species-specific papovavirus DNA replication. J. Virol. 63: 5371–5385.
   PubMedGoogle Scholar
• Bennett-Cook, E. R., and J. A. Hassell. 1991. Activation of polyomavirus DNA replication by yeast GAL4 is dependent on its transcriptional activation domains. EMBO J. 10: 959–969.
   PubMedGoogle Scholar
• Boyd, K. E., J. Wells, J. Gutman, S. M. Bartley, and P. J. Farnham. 1998. c-Myc target gene specificity is determined by a post-DNA binding mechanism. Proc. Natl. Acad. Sci. USA 95: 13887–13892.
   PubMed Web of Science ®Google Scholar
• Brand, M., J. G. Moggs, M. Oulad-Abdelghani, F. Lejeune, F. J. Dilworth, J. Stevenin, G. Almouzni, and L. Tora. 2001. UV-damaged DNA-binding protein in the TFTC complex links DNA damage recognition to nucleosome acetylation. EMBO J. 20: 3187–3196.
   PubMed Web of Science ®Google Scholar
• Burke, T. W., J. G. Cook, M. Asano, and J. R. Nevins. 2001. Replication factors MCM2 and ORC1 interact with the histone acetyltransferase HBO1. J. Biol. Chem. 276: 15397–15408.
   PubMed Web of Science ®Google Scholar
• Candau, R., P. A. Moore, L. Wang, N. Barlev, C. Y. Ying, C. A. Rosen, and S. L. Berger. 1996. Identification of human proteins functionally conserved with the yeast putative adaptors ADA2 and GCN5. Mol. Cell. Biol. 16: 593–602.
   PubMedGoogle Scholar
• Carey, M. Y., Y. S. Lin, M. R. Green, and M. Ptashne. 1990. A mechanism for synergistic activation of a mammalian gene by GAL4 derivatives. Nature 345: 361–363.
   PubMedGoogle Scholar
• Chen, H., M. Tini, and R. M. Evans. 2001. HATs on and beyond chromatin. Curr. Opin. Cell Biol. 13: 218–224.
   PubMed Web of Science ®Google Scholar
• Chen, L., and M. Fluck. 2001. Kinetic analysis of the steps of the polyomavirus lytic cycle. J. Virol. 75: 8368–8379.
   PubMed Web of Science ®Google Scholar
• Chen, L. F., K. Ito, Y. Murakami, and Y. Ito. 1998. The capacity of polyomavirus enhancer binding protein 2αB (AML1/Cbfa2) to stimulate polyomavirus DNA replication is related to its affinity for the nuclear matrix. Mol. Cell. Biol. 18: 4165–4176.
   PubMedGoogle Scholar
• Chen, M. C., D. Redenius, F. Osati-Ashtiani, and M. M. Fluck. 1995. Enhancer-mediated role for polyomavirus middle T/small T in DNA replication. J. Virol. 69: 326–333.
   PubMedGoogle Scholar
• Cheng, L., and T. J. Kelly. 1989. Transcriptional activator nuclear factor I stimulates the replication of SV40 minichromosomes in vivo and in vitro. Cell 59: 541–551.
   PubMedGoogle Scholar
• Cheng, L., J. L. Workman, R. Kinston, and T. J. Kelly. 1992. Regulation of DNA replication in vitro by the transcriptional activation domain of GAL4-VP16. Proc. Natl. Acad. Sci. USA 89: 589–593.
   PubMedGoogle Scholar
• Cho, S. Y., Y. Tian, and T. L. Benjamin. 2001. Binding of p300/CBP co-activators by polyoma large T antigen. J. Biol. Chem. 276: 33533–33539.
   PubMedGoogle Scholar
• Chou, J. Y., and R. G. Martin. 1974. Complementation analysis of simian virus 40 mutants. J. Virol. 13: 1101–1109.
   PubMed Web of Science ®Google Scholar
• Contreras, R., C. Cole, P. Berg, and W. Fiers. 1979. Nucleotide sequence analysis of two simian virus 40 mutants with deletions in the late region of the genome. J. Virol. 29: 789–793.
   PubMedGoogle Scholar
• DePamphilis, M. L. 1993. How transcription factors regulate origins of DNA replication in eukaryotic cells. Trends Cell Biol. 3: 161–167.
   PubMedGoogle Scholar
• DePamphilis, M. L., S. Anderson, R. Bar-Shavit, E. Collins, H. Edenberg, T. Herman, B. Karas, G. Kaufmann, H. Krokan, E. Shelton, R. Su, D. Tapper, and P. M. Wassarman. 1979. Replication and structure of simian virus 40 chromosomes. Cold Spring Harb. Symp. Quant. Biol. 43(Pt 2): 679–692.
   PubMedGoogle Scholar
• de Villiers, J., W. Schaffner, C. Tyndall, S. Lupton, and R. Kamen. 1984. Polyoma virus DNA replication requires an enhancer. Nature 312: 242–246.
   PubMed Web of Science ®Google Scholar
• Freund, R., P. H. Bauer, H. A. Crissman, E. M. Bradbury, and T. L. Benjamin. 1994. Host range and cell cycle activation properties of polyomavirus large T-antigen mutants defective in pRB binding. J. Virol. 68: 7227–7234.
   PubMedGoogle Scholar
• Freund, R., R. T. Bronson, and T. L. Benjamin. 1992. Separation of immortalization from tumor induction with polyoma large T mutants that fail to bind the retinoblastoma gene product. Oncogene 7: 1979–1987.
   PubMedGoogle Scholar
• Gerritsen, M. E., A. J. Williams, A. S. Neish, S. Moore, Y. Shi, and T. Collins. 1997. CREB-binding protein/p300 are transcriptional coactivators of p65. Proc. Natl. Acad. Sci. USA 94: 2927–2932.
   PubMed Web of Science ®Google Scholar
• Gilbert, D. M., A. Neilson, H. Miyazawa, M. L. DePamphilis, and W. C. Burhans. 1995. Mimosine arrests DNA synthesis at replication forks by inhibiting deoxyribonucleotide metabolism. J. Biol. Chem. 270: 9597–9606.
   PubMed Web of Science ®Google Scholar
• Giordano, A., and M. L. Avantaggiati. 1999. P300 and CBP: partners for life and death. J. Cell. Physiol. 181: 218–230.
   PubMed Web of Science ®Google Scholar
• Gruss, C., and R. Knippers. 1995. The SV40 minichromosome, p. 101–113. In K. W. Adolph (ed.), Viral gene techniques. Methods in molecular genetics, vol. 7. Academic Press, San Diego, Calif.
   Google Scholar
• Gruss, C., J. Wu, T. Koller, and J. M. Sogo. 1993. Disruption of the nucleosomes at the replication fork. EMBO J. 12: 4533–4545.
   PubMedGoogle Scholar
• Gu, W., X. L. Shi, and R. G. Roeder. 1997. Synergistic activation of transcription by CBP and p53. Nature 387: 819–823.
   PubMed Web of Science ®Google Scholar
• Guo, Z. S., and M. L. DePamphilis. 1992. Specific transcription factors stimulate simian virus 40 and polyomavirus origins of DNA replication. Mol. Cell. Biol. 12: 2514–2524.
   PubMedGoogle Scholar
• Guo, Z. S., C. Gutierrez, U. Heine, J. M. Sogo, and M. L. DePamphilis. 1989. Origin auxiliary sequences can facilitate initiation of simian virus 40 DNA replication in vitro as they do in vivo. Mol. Cell. Biol. 9: 3593–3602.
   PubMedGoogle Scholar
• Guo, W., W. J. Tang, X. Bu, V. Bermudez, M. Martin, and W. R. Folk. 1996. AP1 enhances polyomavirus DNA replication by promoting T-antigen-mediated unwinding of DNA. J. Virol. 70: 4914–4918.
   PubMedGoogle Scholar
• Gutierrez, C., Z. S. Guo, J. Roberts, and M. L. DePamphilis. 1990. Simian virus 40 origin auxiliary sequences weakly facilitate T-antigen binding but strongly facilitate DNA unwinding. Mol. Cell. Biol. 10: 1719–1728.
   PubMedGoogle Scholar
• He, Z., B. T. Brinton, J. Greenblatt, J. A. Hassell, and C. J. Ingles. 1993. The transactivator proteins VP16 and GAL4 bind replication factor A. Cell 73: 1223–1232.
   PubMedGoogle Scholar
• Hermansen, R., M. A. Sierra, J. Johnson, M. Friez, and B. Milavetz. 1996. Identification of simian virus 40 promoter DNA sequences capable of conferring restriction endonuclease hypersensitivity. J. Virol. 70: 3416–3422.
   PubMedGoogle Scholar
• Hirt, B. 1967. Selective extraction of polyoma DNA from infected mouse cell cultures. J. Mol. Biol. 26: 365–369.
   PubMed Web of Science ®Google Scholar
• Iizuka, M., and B. Stillman. 1999. Histone acetyltransferase HBO1 interacts with the ORC1 subunit of the human initiator protein. J. Biol. Chem. 274: 23027–23034.
   PubMed Web of Science ®Google Scholar
• Ikura, T., V. V. Ogryzko, M. Grigoriev, R. Groisman, J. Wang, M. Horikoshi, R. Scully, J. Qin, and Y. Nakatani. 2000. Involvement of the TIP60 histone acetylase complex in DNA repair and apoptosis. Cell 102: 463–473.
   PubMed Web of Science ®Google Scholar
• Ishikawa, H., M. Asano, T. Kanda, S. Kumar, C. Gelinas, and Y. Ito. 1993. Two novel functions associated with the Rel oncoproteins: DNA replication and cell-specific transcriptional activation. Oncogene 8: 2889–2896.
   PubMedGoogle Scholar
• Ishimi, Y. 1992. Preincubation of T antigen with DNA overcomes repression of SV40 DNA replication by nucleosome assembly. J. Biol. Chem. 267: 10910–10913.
   PubMedGoogle Scholar
• Ito, K., M. Asano, P. Hughes, H. Kohzaki, C. Masutani, F. Hanaoka, T. Kerppola, T. Curran, Y. Murakami, and Y. Ito. 1996. C-Jun stimulates origin-dependent DNA unwinding by polyomavirus large T antigen. EMBO J. 15: 5636–5646.
   PubMedGoogle Scholar
• Jackson, V., D. Granner, and R. Chalkley. 1976. Deposition of histone onto the replicating chromosome: newly synthesized histone is not found near the replication fork. Proc. Natl. Acad. Sci. USA 73: 2266–2269.
   PubMedGoogle Scholar
• Jayaraman, G., R. Srinivas, C. Duggan, E. Ferreira, S. Swaminathan, K. Somasundaram, J. Williams, C. Hauser, M. Kurkinen, R. Dhar, S. Weitzman, G. Buttice, and B. Thimmapaya. 1999. p300/cAMP-responsive element-binding protein interactions with ets-1 and ets-2 in the transcriptional activation of the human stromelysin promoter. J. Biol. Chem. 274: 17342–17352.
   PubMed Web of Science ®Google Scholar
• Jeong, S., and A. Stein. 1994. Micrococcal nuclease digestion of nuclei reveals extended nucleosome ladders having anomalous DNA lengths for chromatin assembled on non-replicating plasmids in transfected cells. Nucleic Acids Res. 22: 370–375.
   PubMed Web of Science ®Google Scholar
• Jeong, S. W., and A. Stein. 1994. DNA sequence affects nucleosome ordering on replicating plasmids in transfected COS-1 cells and in vitro. J. Biol. Chem. 269: 2197–2205.
   PubMedGoogle Scholar
• Kanda, T., K. Segawa, N. Ohuchi, S. Mori, and Y. Ito. 1994. Stimulation of polyomavirus DNA replication by wild-type p53 through the DNA-binding site. Mol. Cell. Biol. 14: 2651–2663.
   PubMedGoogle Scholar
• Kingston, R. E. 1999. Chromatin assembly and analysis, p. 21.0.1–21.1.15. In F. M. Ausubel, R. Brent, R. E. Kingston, D. D. Moore, J. G. Seidman, J. A. Smith, and K. Struhl (ed.), Current protocols in molecular biology. John Wiley & Sons, Inc. New York, N.Y.
   Google Scholar
• Kouzarides, T. 2000. Acetylation: a regulatory modification to rival phosphorylation? EMBO J. 19: 1176–1179.
   PubMed Web of Science ®Google Scholar
• Krumm, A., L. Madisen, X. J. Yang, R. Goodman, Y. Nakatani, and M. Groudine. 1998. Long-distance transcriptional enhancement by the histone acetyltransferase PCAF. Proc. Natl. Acad. Sci. USA 95: 13501–13506.
   PubMedGoogle Scholar
• Kundu, T. K., V. B. Palhan, Z. Wang, W. An, P. A. Cole, and R. G. Roeder. 2000. Activator-dependent transcription from chromatin in vitro involving targeted histone acetylation by p300. Mol. Cell 6: 551–561.
   PubMedGoogle Scholar
• Kurooka, H., and T. Honjo. 2000. Functional interaction between the mouse Notch1 intracellular region and histone acetyltransferases PCAF and GCN5. J. Biol. Chem. 275: 17211–17220.
   PubMed Web of Science ®Google Scholar
• Larose, A., N. Dyson, M. Sullivan, E. Harlow, and M. Bastin. 1991. Polyomavirus large T mutants affected in retinoblastoma protein binding are defective in immortalization. J. Virol. 65: 2308–2313.
   PubMed Web of Science ®Google Scholar
• Lednicky, J., and W. R. Folk. 1992. Two synthetic Sp1-binding sites functionally substitute for the 21-base-pair repeat region to activate simian virus 40 growth in CV-1 cells. J. Virol. 66: 6379–6390.
   PubMedGoogle Scholar
• Lee, J. S., R. H. See, T. Deng, and Y. Shi. 1996. Adenovirus E1A downregulates cJun- and JunB-mediated transcription by targeting their coactivator p300. Mol. Cell. Biol. 16: 4312–4326.
   PubMedGoogle Scholar
• Li, L., B. L. Li, M. Hock, E. Wang, and W. R. Folk. 1995. Sequences flanking the pentanucleotide T-antigen binding sites in the polyomavirus core origin help determine selectivity of DNA replication. J. Virol. 69: 7570–7578.
   PubMedGoogle Scholar
• Li, R. L., and M. R. Botchan. 1993. The acidic transcriptional activation domains of VP16 and p53 bind the cellular replication protein A and stimulate in vitro BPV-1 DNA replication. Cell 73: 1207–1221.
   PubMed Web of Science ®Google Scholar
• Li, R., and M. R. Botchan. 1994. Acidic transcription factors alleviate nucleosome-mediated repression of DNA replication of bovine papillomavirus type 1. Proc. Natl. Acad. Sci. USA 91: 7051–7055.
   PubMedGoogle Scholar
• Lill, N. L., S. R. Grossman, D. Ginsberg, J. DeCaprio, and D. M. Livingston. 1997. Binding and modulation of p53 by p300/CBP coactivators. Nature 387: 823–827.
   PubMed Web of Science ®Google Scholar
• Lipford, J. R., and S. P. Bell. 2001. Nucleosomes positioned by ORC facilitate the initiation of DNA replication. Mol. Cell 7: 21–30.
   PubMed Web of Science ®Google Scholar
• Liu, L., D. M. Scolnick, R. C. Trievel, H. B. Zhang, R. Marmorstein, T. D. Halazonetis, and S. L. Berger. 1999. p53 sites acetylated in vitro by PCAF and p300 are acetylated in vivo in response to DNA damage. Mol. Cell. Biol. 19: 1202–1209.
   PubMed Web of Science ®Google Scholar
• Lundblad, J. R., R. P. Kwok, M. E. Laurance, M. L. Harter, and R. H. Goodman. 1995. Adenoviral E1A-associated protein p300 as a functional homologue of the transcriptional co-activator CBP. Nature 374: 85–88.
   PubMed Web of Science ®Google Scholar
• Martin, M. E., J. Piette, M. Yaniv, W. J. Tang, and W. R. Folk. 1988. Activation of the polyomavirus enhancer by a murine activator protein 1 (AP1) homolog and two contiguous proteins. Proc. Natl. Acad. Sci. USA 85: 5839–5843.
   PubMedGoogle Scholar
• Martinez, E., V. B. Palhan, A. Tjernberg, E. S. Lymar, A. M. Gamper, T. K. Kundu, B. T. Chait, and R. G. Roeder. 2001. Human STAGA complex is a chromatin-acetylating transcription coactivator that interacts with pre-mRNA splicing and DNA damage-binding factors in vivo. Mol. Cell. Biol. 21: 6782–6795.
   PubMed Web of Science ®Google Scholar
• Müeller, C. R., W. J. Muller, and J. A. Hassell. 1988. The polyomavirus enhancer comprises multiple functional elements. J. Virol. 62: 1667–1678.
   PubMedGoogle Scholar
• Müller, K., and N. Mermod. 2000. The histone-interacting domain of nuclear factor I activates simian virus 40 DNA replication in vivo. J. Biol. Chem. 275: 1645–1650.
   PubMedGoogle Scholar
• Müller, U., H. Zentgraf, I. Eicken, and W. Keller. 1978. Higher order structure of simian virus 40 chromatin. Science 201: 406–415.
   PubMedGoogle Scholar
• Murakami, Y., and Y. Ito. 1999. Transcription factors in DNA replication. Front. Biosci. 4: D824–D833.
   PubMedGoogle Scholar
• Murakami, Y., M. Satake, Y. Yamaguchi-Iwai, M. Sakai, M. Muramatsu, and Y. Ito. 1991. The nuclear protooncogenes c-jun and c-fos as regulators of DNA replication. Proc. Natl. Acad. Sci. USA 88: 3947–3951.
   PubMedGoogle Scholar
• Nemethova, M., and E. Wintersberger. 1999. Polyomavirus large T antigen binds the transcriptional coactivator protein p300. J. Virol. 73: 1734–1739.
   PubMedGoogle Scholar
• Nilsson, M., M. Osterlund, and G. Magnusson. 1991. Analysis of polyomavirus enhancer-effect on DNA replication and early gene expression. J. Mol. Biol. 218: 479–483.
   PubMedGoogle Scholar
• Pallas, D. C., C. Schley, M. Mahoney, E. Harlow, B. S. Schaffhausen, and T. M. Roberts. 1986. Polyomavirus small T antigen: overproduction in bacteria, purification, and utilization for monoclonal and polyclonal antibody production. J. Virol. 60: 1075–1084.
   PubMedGoogle Scholar
• Parker, D., K. Ferreri, T. Nakajima, V. J. Lamorte, R. Evans, S. C. Koerber, C. Hoeger, and M. R. Montminy. 1996. Phosphorylation of CREB at Ser-133 induces complex formation with CREB-binding protein via a direct mechanism. Mol. Cell. Biol. 16: 694–703.
   PubMed Web of Science ®Google Scholar
• Peden, K. W., J. M. Pipas, S. Pearson-White, and D. Nathans. 1980. Isolation of mutants of an animal virus in bacteria. Science 209: 1392–1396.
   PubMed Web of Science ®Google Scholar
• Peng, Y. C., and N. H. Acheson. 1998. Polyomavirus large T antigen binds cooperatively to its multiple binding sites in the viral origin of DNA replication. J. Virol. 72: 7330–7340.
   PubMedGoogle Scholar
• Perkins, N. D., L. K. Felzien, J. C. Betts, K. Leung, D. H. Beach, and G. J. Nabel. 1997. Regulation of NF-κB by cyclin-dependent kinases associated with the p300 coactivator. Science 275: 523–527.
   PubMed Web of Science ®Google Scholar
• Piette, J., and M. Yaniv. 1987. Two different factors bind to the alpha-domain of the polyoma virus enhancer, one of which also interacts with the SV40 and c-fos enhancers. EMBO J. 6: 1331–1337.
   PubMedGoogle Scholar
• Pilon, A. A., P. Desjardins, J. A. Hassell, and A. M. Mes-Masson. 1996. Functional implications of mutations within polyomavirus large T antigen Rb-binding domain: effects on pRb and p107 binding in vitro and immortalization activity in vivo. J. Virol. 70: 4457–4465.
   PubMedGoogle Scholar
• Prives, C. 1990. The replication functions of SV40 T antigen are regulated by phosphorylation. Cell 61: 735–738.
   PubMed Web of Science ®Google Scholar
• Puigserver, P., G. Adelmant, Z. Wu, M. Fan, J. Xu, B. O'Malley, and B. M. Spiegelman. 1999. Activation of PPARγ coactivator-1 through transcription factor docking. Science 286: 1368–1371.
   PubMed Web of Science ®Google Scholar
• Quintini, G., K. Treuner, C. Gruss, R. Knippers. 1996. Role of amino-terminal histone domains in chromatin replication. Mol. Cell. Biol. 16: 2888–2897.
   PubMedGoogle Scholar
• Reeves, R., C. M. Gorman, and B. Howard. 1985. Minichromosome assembly of non-integrated plasmid DNA transfected into mammalian cells. Nucleic Acids Res. 13: 3599–3615.
   PubMed Web of Science ®Google Scholar
• Richards, J. P., H. P. Bächinger, R. H. Goodman, and R. G. Brennan. 1996. Analysis of the structural properties of cAMP-responsive element-binding protein (CREB) and phosphorylated CREB. J. Biol. Chem. 271: 13716–13723.
   PubMed Web of Science ®Google Scholar
• Rochford, R., C. T. Davis, K. K. Yoshimoto, and L. P. Villarreal. 1990. Minimal subenhancer requirements for high-level polyomavirus DNA replication: a cell-specific synergy of PEA3 and PEA1 sites. Mol. Cell. Biol. 10: 4996–5001.
   PubMedGoogle Scholar
• Rochford, R., J. P. Moreno, M. L. Peake, and L. P. Villarreal. 1992. Enhancer dependence of polyomavirus persistence in mouse kidneys. J. Virol. 66: 3287–3297.
   PubMedGoogle Scholar
• Roth, S. Y., J. M. Denu, and C. D. Allis. 2001. Histone acetyltransferases. Annu. Rev. Biochem. 70: 81–120.
   PubMed Web of Science ®Google Scholar
• Sanchez, J. A., D. Marek, and L. J. Wangh. 1992. The efficiency and timing of plasmid DNA replication in Xenopus eggs: correlations to the extent of prior chromatin assembly. J. Cell Sci. 103: 907–918.
   PubMedGoogle Scholar
• Shaywitz, A. J., S. L. Dove, J. M. Kornhauser, A. Hochschild, and M. E. Greenberg. 2000. Magnitude of the CREB-dependent transcriptional response is determined by the strength of the interaction between the kinase-inducible domain of CREB and the KIX domain of CREB-binding protein. Mol. Cell. Biol. 20: 9409–9422.
   PubMed Web of Science ®Google Scholar
• Spencer, T. E., G. Jenster, M. M. Burcin, C. D. Allis, J. Zhou, C. A. Mizzen, N. J. McKenna, S. A. Onate, S. Y. Tsai, M. J. Tsai, and B. W. O'Malley. 1997. Steroid receptor coactivator-1 is a histone acetyltransferase. Nature 389: 194–198.
   PubMed Web of Science ®Google Scholar
• Sterner, D. E., and S. L. Berger. 2000. Acetylation of histones and transcription-related factors. Microbiol. Mol. Biol. Rev. 64: 435–459.
   PubMed Web of Science ®Google Scholar
• Strahl, B. D., and C. D. Allis. 2000. The language of covalent histone modification. Nature 403: 41–45.
   PubMed Web of Science ®Google Scholar
• Struhl, K. 1998. Histone acetylation and transcriptional regulatory mechanisms. Genes Dev. 12: 599–606.
   PubMed Web of Science ®Google Scholar
• Stuiver, M. H., W. G. Bergsma, A. C. Arnberg, H. van Amerongen, R. van Grondelle, and P. C. van der Vliet. 1992. Structural alterations of double-stranded DNA in complex with the adenovirus DNA-binding protein. Implications for its function in DNA replication. J. Mol. Biol. 225: 999–1011.
   PubMedGoogle Scholar
• Sun, D., and L. H. Hurley. 1994. Cooperative bending of the 21-base-pair repeats of the SV40 viral early promoter by human Sp1. Biochemistry 33: 9578–9587.
   PubMed Web of Science ®Google Scholar
• Suzuki, T., A. Kimura, R. Nagai, and M. Horikoshi. 2000. Regulation of interaction of the acetyltransferase region of p300 and the DNA-binding domain of Sp1 on and through DNA binding. Genes Cells 5: 29–41.
   PubMedGoogle Scholar
• Swope, D. L., C. L. Mueller, and J. C. Chrivia. 1996. CREB-binding protein activates transcription through multiple domains. J. Biol. Chem. 271: 28138–28145.
   PubMedGoogle Scholar
• Takei, Y., M. Swietlik, A. Tanoue, G. Tsujimoto, T. Kouzarides, and R. Laskey. 2001. MCM3AP, a novel acetyltransferase that acetylates replication protein MCM3. EMBO Rep. 2: 119–123.
   PubMed Web of Science ®Google Scholar
• Tang, W. J., and W. R. Folk. 1989. Asp-286 224 Asn-286 in polyomavirus large T antigen relaxes the specificity of binding to the polyomavirus origin. J. Virol. 63: 242–249.
   PubMedGoogle Scholar
• Tang, W. J., S. L. Berger, S. J. Triezenberg, and W. R. Folk. 1987. Nucleotides in the polyomavirus enhancer that control viral transcription and DNA replication. Mol. Cell. Biol. 7: 1681–1690.
   PubMedGoogle Scholar
• Turner, W. J., and M. E. Woodworth. 2001. DNA replication efficiency depends on transcription factor-binding sites. J. Virol. 75: 5638–5645.
   PubMedGoogle Scholar
• Utley, R. T., K. Ikeda, P. A. Grant, J. Cote, D. J. Steger, A. Eberharter, S. John, and J. L. Workman. 1998. Transcriptional activators direct histone acetyltransferase complexes to nucleosomes. Nature 394: 498–502.
   PubMed Web of Science ®Google Scholar
• Verrijzer, C. P., J. A. van Oosterhout, W. W. van Weperen, and P. C. van der Vliet. 1991. POU proteins bend DNA via the POU-specific domain. EMBO J. 10: 3007–3014.
   PubMedGoogle Scholar
• Vries, R. G., M. Prudenziati, C. Zwartjes, M. Verlaan, E. Kalkhoven, and A. Zantema. 2001. A specific lysine in c-Jun is required for transcriptional repression by E1A and is acetylated by p300. EMBO J. 20: 6095–6103.
   PubMed Web of Science ®Google Scholar
• Wang, L., S. R. Grossman, and E. Kieff. 2000. Epstein-Barr virus nuclear protein 2 interacts with p300, CBP, and PCAF histone acetyltransferases in activation of the LMP1 promoter. Proc. Natl. Acad. Sci. USA 97: 430–435.
   PubMed Web of Science ®Google Scholar
• Wasylyk, C., J. Schneikert, and B. Wasylyk. 1990. Oncogene v-jun modulates DNA replication. Oncogene 5: 1055–1058.
   PubMedGoogle Scholar
• Weisshart, K., and E. Fanning. 1996. Roles of phosphorylation in DNA replication, p. 295–330. In M. L. Depamphilis (ed.), DNA replication in eukaryotic cells. Cold Spring Harbor Laboratory Press, New York, N.Y.
   Google Scholar
• Wilderman, P. J., B. Hu, and M. E. Woodworth. 1999. Conformational changes in simian virus 40 rearranged regulatory regions: effects of the 21-base-pair promoters and their location. J. Virol. 73: 10254–10263.
   PubMedGoogle Scholar
• Xu, W., D. G. Edmondson, and S. Y. Roth. 1998. Mammalian GCN5 and P/CAF acetyltransferases have homologous amino-terminal domains important for recognition of nucleosomal substrates. Mol. Cell. Biol. 18: 5659–5669.
   PubMedGoogle Scholar
• Yang, X. J., V. V. Ogryzko, J. Nishikawa, B. H. Howard, and Y. Nakatani. 1996. A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A. Nature 382: 319–324.
   PubMed Web of Science ®Google Scholar
• Yang, C., L. H. Shapiro, M. Rivera, A. Kumar, and P. K. Brindle. 1998. A role for CREB binding protein and p300 transcriptional coactivators in Ets-1 transactivation functions. Mol. Cell. Biol. 18: 2218–2229.
   PubMed Web of Science ®Google Scholar
• Yoshida, M., M. Kijima, M. Akita, and T. Beppu. 1990. Potent and specific inhibition of mammalian histone deacetylase both in vivo and in vitro by trichostatin A. J. Biol. Chem. 265: 17174–17179.
   PubMed Web of Science ®Google Scholar
• Yoshida, M., S. Horinouchi, and T. Beppu. 1995. Trichostatin A and trapoxin-novel chemical probes for the role of histone acetylation in chromatin structure and function. BioEssays 17: 423–430.
   PubMed Web of Science ®Google Scholar
• Yuan, W., G. Condorelli, M. Caruso, A. Felsani, and A. J. Giordano. 1996. Human p300 protein is a coactivator for the transcription factor MyoD. J. Biol. Chem. 271: 9009–9013.
   PubMed Web of Science ®Google Scholar