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Cell Growth and Development

Regulation of Notch1 and Dll4 by Vascular Endothelial Growth Factor in Arterial Endothelial Cells: Implications for Modulating Arteriogenesis and Angiogenesis

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Pages 14-25 | Received 19 Jun 2002, Accepted 04 Oct 2002, Published online: 27 Mar 2023

REFERENCES

  • Artavanis-Tsakonas, S., K. Matsuno, and M. E. Fortini. 1995. Notch signaling. Science 268: 225–232.
  • Bellavia, D., A. F. Campese, E. Alesse, A. Vacca, M. P. Felli, A. Balestri, A. Stoppacciaro, C. Tiveron, L. Tatangelo, M. Giovarelli, C. Gaetano, L. Ruco, E. S. Hoffman, A. C. Hayday, U. Lendahl, L. Frati, A. Gulino, and I. Screpanti. 2000. Constitutive activation of NF-kappaB and T-cell leukemia/lymphoma in Notch3 transgenic mice. EMBO J. 19: 3337–3348.
  • Byzova, T. V., C. K. Goldman, N. Pampori, K. A. Thomas, A. Bett, S. J. Shattil, and E. F. Plow. 2000. A mechanism for modulation of cellular responses to VEGF: activation of the integrins. Mol. Cell 6: 851–860.
  • Carmeliet, P. 2000. Mechanisms of angiogenesis and arteriogenesis. Nat. Med. 6: 389–395.
  • Chung, C. N., Y. Hamaguchi, T. Honjo, and M. Kawaichi. 1994. Site-directed mutagenesis study on DNA binding regions of the mouse homologue of Suppressor of Hairless, RBP-Jκ. Nucleic Acids Res. 22: 2938–2944.
  • Cooper, M. T., and S. J. Bray. 1999. Frizzled regulation of Notch signaling polarizes cell fate in the Drosophila eye. Nature 397: 526–530.
  • Dayanir, V., R. D. Meyer, K. Lashkari, and N. Rahimi. 2001. Identification of tyrosine residues in vascular endothelial growth factor receptor-2/FLK-1 involved in activation of phosphatidylinositol 3-kinase and cell proliferation. J. Biol. Chem. 276: 17686–17692.
  • Fanto, M., and M. Mlodzik. 1999. Asymmetric Notch activation specifies photoreceptors R3 and R4 and planar polarity in the Drosophila eye. Nature 397: 523–526.
  • Fong, G. H., J. Rossant, M. Gertsenstein, and M. L. Breitman. 1995. Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium. Nature 376: 66–70.
  • Hanahan, D. 1997. Signaling vascular morphogenesis and maintenance. Science 277: 48–50.
  • He, T. C., S. Zhou, L. T. da Costa, J. Yu, K. W. Kinzler, and B. Vogelstein. 1998. A simplified system for generating recombinant adenoviruses. Proc. Natl. Acad. Sci. USA 95: 2509–2514.
  • Henderson, A. M., S. J. Wang, A. C. Taylor, M. Aitkenhead, and C. C. Hughes. 2001. The basic helix-loop-helix transcription factor HESR1 regulates endothelial cell tube formation. J. Biol. Chem. 276: 6169–6176.
  • Hrabe de Angelis, M., J. McIntyre second, and A. Gossler. 1997. Maintenance of somite borders in mice requires the Delta homologue Dll1. Nature 386: 717–721.
  • Huang, K., C. Andersson, G. M. Roomans, N. Ito, and L. Claesson-Welsh. 2001. Signaling properties of VEGF receptor-1 and -2 homo- and heterodimers. Int. J. Biochem. Cell Biol. 33: 315–324.
  • Huppert, S. S., A. Le, E. H. Schroeter, J. S. Mumm, M. T. Saxena, L. A. Milner, and R. Kopan. 2000. Embryonic lethality in mice homozygous for a processing-deficient allele of Notch1. Nature 405: 966–970.
  • Joutel, A., C. Corpechot, A. Ducros, K. Vahedi, H. Chabriat, P. Mouton, S. Alamowitch, V. Domenga, M. Cecillion, E. Marechal, J. Maciazek, C. Vayssiere, C. Cruaud, E. A. Cabanis, M. M. Ruchoux, J. Weissenbach, J. F. Bach, M. G. Bousser, and E. Tournier-Lasserve. 1996. Notch3 mutations in CADASIL, a hereditary adult-onset condition causing stroke and dementia. Nature 383: 707–710.
  • Kaipainen, A., J. Korhonen, T. Mustonen, V. W. van Hinsbergh, G. H. Fang, D. Dumont, M. Breitman, and K. Alitalo. 1995. Expression of the fms-like tyrosine kinase 4 gene becomes restricted to lymphatic endothelium during development. Proc. Natl. Acad. Sci. USA 92: 3566–3570.
  • Kitamura, T., Y. Kitamura, S. Kuroda, Y. Hino, M. Ando, K. Kotani, H. Konishi, H. Matsuzaki, U. Kikkawa, W. Ogawa, and M. Kasuga. 1999. Insulin-induced phosphorylation and activation of cyclic nucleotide phosphodiesterase 3B by the serine-threonine kinase Akt. Mol. Cell. Biol. 19: 6286–6296.
  • Kotani, K., W. Ogawa, Y. Hino, T. Kitamura, H. Ueno, W. Sano, C. Sutherland, D. K. Granner, and M. Kasuga. 1999. Dominant negative forms of Akt (protein kinase B) and atypical protein kinase Cλ do not prevent insulin inhibition of phosphoenolpyruvate carboxykinase gene transcription. J. Biol. Chem. 274: 21305–21312.
  • Krebs, L. T., Y. Xue, C. R. Norton, J. R. Shutter, M. Maguire, J. P. Sundberg, D. Gallahan, V. Closson, J. Kitajewski, R. Callahan, G. H. Smith, K. L. Stark, and T. Gridley. 2000. Notch signaling is essential for vascular morphogenesis in mice. Genes Dev. 14: 1343–1352.
  • Kurooka, H., K. Kuroda, and T. Honjo. 1998. Roles of the ankyrin repeats and C-terminal region of the mouse notch1 intracellular region. Nucleic Acids Res. 26: 5448–5455.
  • Leimeister, C., N. Schumacher, C. Steidl, and M. Gessler. 2000. Analysis of HeyL expression in wild-type and Notch pathway mutant mouse embryos. Mech. Dev. 98: 175–178.
  • Liu, Z.-J., T. Ueda, T. Miyazaki, N. Tanaka, S. Mine, Y. Tanaka, T. Taniguchi, H. Yamamura, and Y. Minami. 1998. A critical role for cyclin C in promotion of the hematopoietic cell cycle by cooperation with c-Myc. Mol. Cell. Biol. 18: 3445–3454.
  • Liu, Z.-J., H. Haleem-Smith, H. Chen, and H. Metzger. 2001. Unexpected signals in a system subject to kinetic proofreading. Proc. Natl. Acad. Sci. USA 98: 7289–7294.
  • Luo, B., J. C. Aster, R. P. Hasserjian, F. Kuo, and J. Sklar. 1997. Isolation and functional analysis of a cDNA for human Jagged2, a gene encoding a ligand for the Notch1 receptor. Mol. Cell. Biol. 17: 6057–6067.
  • Mignatti, P., T. Morimoto, and D. B. Rifkin. 1992. Basic fibroblast growth factor, a protein devoid of secretory signal sequence, is released by cells via a pathway independent of the endoplasmic reticulum-Golgi complex. J. Cell Physiol. 151: 81–93.
  • Missero, C. E., Calautti, R. Eckner, J. Chin, L. H. Tsai, D. M. Livingston, and G. P. Dotto. 1995. Involvement of the cell-cycle inhibitor Cip1/WAF1 and the E1A-associated p300 protein in terminal differentiation. Proc. Natl. Acad. Sci. USA 92: 5451–5455.
  • Mumm, J. S., and R. Kopan. 2000. Notch signaling: from the outside in. Dev. Biol. 228: 151–165.
  • Nesbit, M., H. K. Nesbit, J. Bennett, T. Andl, M. Y. Hsu, E. Dejesus, M. McBrian, A. R. Gupta, S. L. Eck, and M. Herlyn. 1999. Basic fibroblast growth factor induces a transformed phenotype in normal human melanocytes. Oncogene 18: 6469–6476.
  • Ohtsuka, T., M. Ishibashi, G. Gradwohl, S. Nakanishi, F. Guillemot, and R. Kageyama. 1999. Hes1 and Hes5 as Notch effectors in mammalian neuronal differentiation. EMBO J. 18: 2196–2207.
  • Petrova, T. V., T. Makinen, and K. Alitalo. 1999. Signaling via vascular Endothelial growth factor receptors. Exp. Cell Res. 253: 117–130.
  • Rangarajan, A., C. Talora, R. Okuyama, M. Nicolas, C. Mammucari, H. Oh, J. C. Aster, S. Krishna, D. Metzger, P. Chambon, L. Miele, M. Aguet, F. Radtke, and G. P. Dotto. 2001. Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation. EMBO J. 20: 3427–3436.
  • Sakaue, H., W. Ogawa, M. Takata, S. Kuroda, K. Kotani, M. Matsumoto, M. Sakaue, S. Nishio, H. Ueno, and M. Kasuga. 1997. Phosphoinositide 3-kinase is required for insulin-induced but not for growth hormone- or hyperosmolarity-induced glucose uptake in 3T3-L1 adipocytes. Mol. Endocrinol. 11: 1552–1562.
  • Shalaby, F., J. Rossant, T. P. Yamaguchi, M. Gertsenstein, X. F. Wu, M. L. Breitman, and A. C. Schuh. 1995. Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice. Nature 376: 62–66.
  • Shutter, J. R., S. Scully, W. Fan, W. G. Richards, J. Kitajewski, G. A. Deblandre, C. R. Kintner, and K. L. Stark. 2000. Dll4, a novel Notch ligand expressed in arterial endothelium. Genes Dev. 14: 1313–1318.
  • Smithers, L., C. Haddon, Y. Jiang, and J. Lewis. 2000. Sequence and embryonic expression of deltaC in the zebrafish. Mech. Dev. 90: 119–123.
  • Soker, S., S. Takashima, H. Q. Miao, G. Neufeld, and M. Klagsbrun. 1998. Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor. Cell 92: 735–745.
  • Sriuranpong, V., M. W. Borges, R. K. Ravi, D. R. Arnold, B. D. Nelkin, S. B. Baylin, and D. W. Ball. 2001. Notch signaling induces cell cycle arrest in small cell lung cancer cells. Cancer Res. 61: 3200–3205.
  • Stokoe, D., L. R. Stephens, T. Copeland, P. R. Gaffney, C. B. Reese, G. F. Painter, A. B. Holmes, F. McCormick, and P. T. Hawkins. 1997. Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B. Science 277: 567–570.
  • Thakker, G. D., D. P. Hajjar, W. A. Muller, and T. K. Rosengart. 1999. The role of phosphatidylinositol 3-kinase in vascular endothelial growth factor signaling. J. Biol. Chem. 274: 10002-10007
  • Tsai, S., J. Fero, and S. Bartelmez. 2000. Mouse Jagged2 is differentially expressed in hematopoietic progenitors and endothelial cells and promotes the survival and proliferation of hematopoietic progenitors by direct cell-to-cell contact. Blood 96: 950–957.
  • Uyttendaele, H., G. Marazzi, G. Wu, Q. Yan, D. Sassoon, and J. Kitajewski. 1996. Notch4/int-3, a mammary proto-oncogene, is an endothelial cell-specific mammalian Notch gene. Development 122: 2251–2259.
  • Uyttendaele, H., J. Ho, J. Rossant, and J. Kitajewski. 2001. Vascular patterning defects associated with expression of activated Notch4 in embryonic endothelium. Proc. Natl. Acad. Sci. USA 98: 5643–5648.
  • Veikkola, T., and K. Alitalo. 1999. VEGFs, receptors and angiogenesis. Semin. Cancer Biol. 9: 211–220.
  • Velazquez, O. C., R. Snyder, Z.-J. Liu, R. M. Fairman, and M. Herlyn. 2002. Fibroblast-dependent differentiation of human microvascular endothelial cells into capillary-like, three-dimensional networks. FASEB J. 16: 1316–1318.
  • Villa, N., L. Walker, C. E. Lindsell, J. Gasson, M. L. Iruela-Arispe, and G. Weinmaster. 2001. Vascular expression of Notch pathway receptors and ligands is restricted to arterial vessels. Mech. Dev. 108: 161–164.
  • Wang, H. U., Z. F. Chen, and D. J. Anderson. 1998. Molecular distinction and angiogenic interaction between embryonic arteries and veins revealed by ephrin-B2 and its receptor Eph-B4. Cell 93: 741–753.
  • Weinmaster, G. 2000. Notch signal transduction: a real rip and more. Curr. Opin. Genet. Dev. 10: 363–369.
  • Xue, Y., X. Gao, C. E. Lindsell, C. R. Norton, B. Chang, C. Hicks, M. Gendron-Maguire, E. B. Rand, G. Weinmaster, and T. Gridley. 1999. Embryonic lethality and vascular defects in mice lacking the Notch ligand Jagged1. Hum. Mol. Genet. 8: 723–730.
  • Yancopoulos, G. D., S. Davis, N. W. Gale, J. S. Rudge, S. J. Wiegand, and J. Holash. 2000. Vascular-specific growth factors and blood vessel formation. Nature 407: 242–248.
  • Zhong, T. P., M. Rosenberg, M. A., Mohideen, B. Weinstein, and M. C. Fishman. 2000. gridlock, an HLH gene required for assembly of the aorta in zebrafish. Science 287: 1820–1824.
  • Zhong, T. P., S. Childs, J. P. Leu, and M. C. Fishman. 2001. Gridlock signalling pathway fashions the first embryonic artery. Nature 414: 216–220.
  • Zimrin, A. B., M. S. Pepper, G. A. McMahon, F. Nguyen, R. Montesano, and T. Maciag. 1996. An antisense oligonucleotide to the notch ligand jagged enhances fibroblast growth factor-induced angiogenesis in vitro. J. Biol. Chem. 271: 32499–32502.

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