Cdk7 Is Required for Full Activation of Drosophila Heat Shock Genes and RNA Polymerase II Phosphorylation In Vivo

REFERENCES

• Akoulitchev, S., T. P. Makela, R. A. Weinberg, and D. Reinberg. 1995. Requirement for TFIIH kinase activity in transcription by RNA polymerase II. Nature 377: 557–560.
   PubMedGoogle Scholar
• Albert, T., J. Mautner, J. O. Funk, K. Hoertnagel, A. Pullner, and D. Eick. 1997. Nucleosomal structures of c-myc promoters with transcriptionally engaged RNA polymerase II. Mol. Cell. Biol. 17: 4363–4371.
   PubMedGoogle Scholar
• Andrulis, E. D., E. Guzman, P. Doring, J. Werner, and J. T. Lis. 2000. High-resolution localization of Drosophila Spt5 and Spt6 at heat shock genes in vivo: roles in promoter proximal pausing and transcription elongation. Genes Dev. 14: 2635–2649.
   PubMed Web of Science ®Google Scholar
• Ausubel, F. M., R. Brent, R. E. Kingston, D. D. Moore, J. G. Seidman, J. A. Smith, and K. Struhl (ed.). 1997. Current protocols in molecular biology. John Wiley & Sons, New York, N.Y.
   Google Scholar
• Boehm, A. K., A. Saunders, J. Werner, and J. T. Lis. Transcription factor and polymerase recruitment, modification, and movement on dhsp70 in vivo in the minutes following heat shock. Mol. Cell Biol. in press.
   Google Scholar
• Brown, S. A., and R. E. Kingston. 1997. Disruption of downstream chromatin directed by a transcriptional activator. Genes Dev. 11: 3116–3121.
   PubMed Web of Science ®Google Scholar
• Chao, S. H., and D. H. Price. 2001. Flavopiridol inactivates P-TEFb and blocks most RNA polymerase II transcription in vivo. J. Biol. Chem. 276: 31793–31799.
   PubMed Web of Science ®Google Scholar
• Chen, D., and Q. Zhou. 1999. Tat activates human immunodeficiency virus type 1 transcriptional elongation independent of TFIIH kinase. Mol. Cell. Biol. 19: 2863–2871.
   PubMed Web of Science ®Google Scholar
• Cheng, C., and P. A. Sharp. 2003. RNA polymerase II accumulation in the promoter-proximal region of the dihyhydrofolate reductase and γ-actin genes. Mol. Cell. Biol. 23: 1961–1967.
   PubMedGoogle Scholar
• Cismowski, M. J., G. M. Laff, M. J. Solomon, and S. I. Reed. 1995. KIN28 encodes a C-terminal domain kinase that controls mRNA transcription in Saccharomyces cerevisiae but lacks cyclin-dependent kinase-activating kinase (CAK) activity. Mol. Cell. Biol. 15: 2983–2992.
   PubMedGoogle Scholar
• Crowley, T. E., and E. M. Meyerowitz. 1984. Steroid regulation of RNAs transcribed from the Drosophila 68C polytene chromosome puff. Dev. Biol. 102: 110–121.
   PubMedGoogle Scholar
• Dvir, A., R. C. Conaway, and J. W. Conaway. 1997. A role for TFIIH in controlling the activity of early RNA polymerase II elongation complexes. Proc. Natl. Acad. Sci. USA 94: 9006–9010.
   PubMedGoogle Scholar
• Gilmour, D. S., and J. T. Lis. 1985. In vivo interactions of RNA polymerase II with genes of Drosophila melanogaster. Mol. Cell. Biol. 5: 2009–2018.
   PubMed Web of Science ®Google Scholar
• Gilmour, D. S., and J. T. Lis. 1986. RNA polymerase II interacts with the promoter region of the noninduced hsp70 gene in Drosophila melanogaster cells. Mol. Cell. Biol. 6: 3984–3989.
   PubMed Web of Science ®Google Scholar
• Guzman, E., and J. T. Lis. 1999. Transcription factor TFIIH is required for promoter melting in vivo. Mol. Cell. Biol. 8: 5652–5658.
   Google Scholar
• Iben, S., H. Tschochner, M. Bier, D. Hoogstraten, P. Hozak, J. M. Egly, and I. Grummt. 2002. TFIIH plays an essential role in RNA polymerase I transcription. Cell 109: 297–306.
   PubMedGoogle Scholar
• Krumm, A., T. Meulia, M. Brunvand, and M. Groudine. 1992. The block to transcriptional elongation within the human c-myc gene is determined in the promoter-proximal region. Genes Dev. 6: 2201–2213.
   PubMed Web of Science ®Google Scholar
• Krumm, A., L. B. Hickey, and M. Groudine. 1995. Promoter-proximal pausing of RNA polymerase II defines a general rate-limiting step after transcription initiation. Genes Dev. 9: 559–572.
   PubMed Web of Science ®Google Scholar
• Larochelle, S., J. Chen, R. Knights, J. Pandur, P. Morcillo, H. Erdjument-Bromage, P. Tempst, B. Suter, and R. P. Fisher. 2001. T-loop phosphorylation stabilizes the CDK7-cyclin H-MAT1 complex in vivo and regulates its CTD kinase activity. EMBO J. 20: 3749–3759.
   PubMed Web of Science ®Google Scholar
• Larochelle, S., J. Pandur, R. Fisher, H. Salz, and B. Suter. 1998. Cdk7 is essential for mitosis and for in vivo Cdk-activating kinase activity. Genes Dev. 12: 370–381.
   PubMed Web of Science ®Google Scholar
• Larochelle, S., and R. P. Fisher. 2002. Drosophila CDK7: a paradigm for CAK in metazoans, p. 39–53. In P. Kaldis (ed.), The CDK-activating kinase (CAK). Landes Bioscience Publishers, Georgetown, Tex.
   Google Scholar
• Laybourn, P. J., and M. E. Dahmus. 1990. Phosphorylation of RNA polymerase IIA occurs subsequent to interaction with the promoter and before the initiation of transcription. J. Biol. Chem. 265: 13165–13173.
   PubMedGoogle Scholar
• Leclerc, V., S. Raisin, and P. Leopold. 2000. Dominant-negative mutants reveal a role for the Cdk7 kinase at the mid-blastula transition in Drosophila embryos. EMBO J. 19: 1567–1575.
   PubMedGoogle Scholar
• Lee, D., and J. T. Lis. 1998. Transcriptional activation independent of TFIIH kinase and the RNA polymerase II mediator in vivo. Nature 393: 389–392.
   PubMedGoogle Scholar
• Lee, H., K. W. Kraus, M. F. Wolfner, and J. T. Lis. 1992. DNA sequence requirements for generating paused polymerase at the start of hsp70. Genes Dev. 6: 284–295.
   PubMedGoogle Scholar
• Lis, J. T., P. Mason, J. Peng, D. H. Price, and J. Werner. 2000. P-TEFb kinase recruitment and function at heat shock loci. Genes Dev. 14: 792–803.
   PubMed Web of Science ®Google Scholar
• Lis, J. T., D. Ish-Horowicz, and S. M. Pinchin. 1981. Genomic organization and transcription of the alpha beta heat shock DNA in Drosophila melanogaster. Nucleic Acids Res. 9: 5297–5310.
   PubMedGoogle Scholar
• Lis, J. T., L. Prestidge, and D. S. Hogness. 1978. A novel arrangement of tandemly repeated genes at a major heat shock site in D. melanogaster. Cell 14: 901–919.
   PubMed Web of Science ®Google Scholar
• Lis, J. T., W. Neckameyer, R. Dubensky, and N. Costlow. 1981. Cloning and characterization of nine heat-shock-induced mRNAs of Drosophila melanogaster. Gene 15: 67–80.
   PubMedGoogle Scholar
• Lis, J. T., J. A. Simon, and C. A. Sutton. 1983. New heat shock puffs and beta-galactosidase activity resulting from transformation of Drosophila with an hsp70-lacZ hybrid gene. Cell 35: 403–410.
   PubMed Web of Science ®Google Scholar
• Lu, H., O. Flores, R. Weinmann, and D. Reinberg. 1991. The nonphosphorylated form of RNA polymerase II preferentially associates with the preinitiation complex. Proc. Natl. Acad. Sci. USA 88: 10004–10008.
   PubMed Web of Science ®Google Scholar
• Makela, T. P., J. D. Parvin, J. Kim, L. J. Huber, P. A. Sharp, and R. A. Weinberg. 1995. A kinase-deficient transcription factor TFIIH is functional in basal and activated transcription. Proc. Natl. Acad. Sci. USA 92: 5174–5178.
   PubMed Web of Science ®Google Scholar
• Marshall, N. F., J. Peng, Z. Xie, and D. H. Price. 1996. Control of RNA polymerase II elongation potential by a novel carboxyl-terminal domain kinase. J. Biol. Chem. 271: 27176–27183.
   PubMed Web of Science ®Google Scholar
• McNeil, J. B., H. Agah, and D. Bentley. 1998. Activated transcription independent of the RNA polymerase II holoenzyme in budding yeast. Genes Dev. 12: 2510–2521.
   PubMedGoogle Scholar
• Merino, C., E. Reynaud, M. Vazquez, and M. Zurita. 2002. DNA repair and transcriptional effects of mutations in TFIIH in Drosophila development. Mol. Biol. Cell. 13: 3246–3256.
   PubMedGoogle Scholar
• O'Brien, T., S. Hardin, A. Greenleaf, and J. T. Lis. 1994. Phosphorylation of RNA polymerase II C-terminal domain and transcriptional elongation. Nature 370: 75–77.
   PubMed Web of Science ®Google Scholar
• O'Brien, T., and J. T. Lis. 1993. Rapid changes in Drosophila transcription after an instantaneous heat shock. Mol. Cell. Biol. 13: 3456–3463.
   PubMedGoogle Scholar
• Plet, A., D. Eick, and J. M. Blanchard. 1995. Elongation and premature termination of transcripts initiated from c-fos and c-myc promoters show dissimilar patterns. Oncogene 10: 319–328.
   PubMed Web of Science ®Google Scholar
• Rasmussen, E., and J. T. Lis. 1993. In vivo transcriptional pausing and cap formation on three Drosophila heat shock genes. Proc. Natl. Acad. Sci. USA 90: 7923–7927.
   PubMed Web of Science ®Google Scholar
• Rossi, D. J., A. Londesborough, N. Korsisaari, A. Pihlak, E. Lehtonen, M. Henkemeyer, and T. P. Makela. 2001. Inability to enter S phase and defective RNA polymerase II CTD phosphorylation in mice lacking Mat1. EMBO J. 20: 2844–2856.
   PubMedGoogle Scholar
• Rougvie, A., and J. T. Lis. 1990. Postinitiation transcription control in Drosophila melonagaster. Mol. Cell. Biol. 10: 6041–6045.
   PubMedGoogle Scholar
• Simon, J. A., C. A. Sutton, R. B. Lobell, R. L. Glaser, and J. T. Lis. 1985. Determinants of heat shock-induced chromosome puffing. Cell 40: 805–817.
   PubMedGoogle Scholar
• Tirode, F., D. Busso, F. Coin, and J. M. Egly. 1999. Reconstitution of the transcription factor TFIIH: assignment of functions for the three enzymatic subunits, XPB, XPD, and Cdk7. Mol. Cell 3: 87–95.
   PubMed Web of Science ®Google Scholar
• Valay, J. G., M. Simon, M. F. Dubois, O. Bensaude, C. Facca, and G. Faye. 1995. The KIN28 gene is required both for RNA polymerase II mediated transcription and phosphorylation of the Rpb1p CTD. J. Mol. Biol. 249: 535–544.
   PubMedGoogle Scholar
• Wallenfang, M., and G. Seydoux. 2002. cdk-7 is required for mRNA transcription and cell cycle progression in Caenorhabditis elegans embryos. Proc. Natl. Acad. Sci. USA 99: 5527–5532.
   PubMedGoogle Scholar
• Wen, Y., and A. J. Shatkin. 1999. Transcription elongation factor hSPT5 stimulates mRNA capping. Genes Dev. 13: 1774–1779.
   PubMed Web of Science ®Google Scholar
• Winegarden, N. A., K. S. Wong, M. Sopta, and J. T. Westwood. 1996. Sodium salicyclate decreases intracellular ATP, induces both heat shock factor binding and chromosomal puffing, but does not induce hsp70 gene transcription in Drosophila. J. Biol. Chem. 271: 26971–26980.
   PubMedGoogle Scholar
• Zawel, L., K. P. Kumar, and D. Reinberg. 1995. Recycling of the general transcription factors during RNA polymerase II transcription. Genes Dev. 9: 1479–1490.
   PubMedGoogle Scholar
• Zhou, M., M. A. Halanski, M. F. Radonovich, F. Kashanchi, J. Peng, D. H. Price, and J. N. Brady. 2000. Tat modifies the activity of CDK9 to phosphorylate serine 5 of the RNA polymerase II carboxyl-terminal domain during human immunodeficiency virus type 1 transcription. Mol. Cell. Biol. 20: 5077–5086.
   PubMed Web of Science ®Google Scholar