A Novel Human Ada2 Homologue Functions with Gcn5 or Brg1 To Coactivate Transcription

REFERENCES

• Aasland, R., A. F. Stewart, and T. Gibson. 1996. The SANT domain: a putative DNA-binding domain in the SWI-SNF and ADA complexes, the transcriptional co-repressor N-CoR and TFIIIB. Trends Biochem. Sci. 21: 87–88.
   PubMed Web of Science ®Google Scholar
• Barlev, N. A., R. Candau, L. Wang, P. Darpino, N. Silverman, and S. L. Berger. 1995. Characterization of physical interactions of the putative transcriptional adaptor, ADA2, with acidic activation domains and TATA-binding protein. J. Biol. Chem. 270: 19337–19344.
   PubMedGoogle Scholar
• Barlev, N. A., L. Liu, N. H. Chehab, K. Mansfield, K. G. Harris, T. D. Halazonetis, and S. L. Berger. 2001. Acetylation of p53 activates transcription through recruitment of coactivators/histone acetyltransferases. Mol. Cell 8: 1243–1254.
   PubMed Web of Science ®Google Scholar
• Bell, B., E. Scheer, and L. Tora. 2001. Identification of hTAF(II)80 delta links apoptotic signaling pathways to transcription factor TFIID function. Mol. Cell 8: 591–600.
   PubMedGoogle Scholar
• Bell, B., and L. Tora. 1999. Regulation of gene expression by multiple forms of TFIID and other novel TAFII-containing complexes. Exp. Cell Res. 246: 11–19.
   PubMedGoogle Scholar
• Belotserkovskaya, R., and S. L. Berger. 2003. Interplay between chromatin modifying and remodeling complexes in transcriptional regulation. Crit. Rev. Eukaryot. Gene Expr. 9: 221–230.
   Google Scholar
• Berger, S. L., B. Piña, N. Silverman, G. A. Marcus, J. Agapite, J. L. Regier, S. J. Triezenberg, and L. Guarente. 1992. Genetic isolation of ADA2: a potential transcriptional adaptor required for function of certain acidic activation domains. Cell 70: 251–265.
   PubMedGoogle Scholar
• Boyer, L. A., M. R. Langer, K. A. Crowley, S. Tan, J. M. Denu, and C. L. Peterson. 2002. Essential role for the SANT domain in the functioning of multiple chromatin remodeling enzymes. Mol. Cell 10: 935–942.
   PubMed Web of Science ®Google Scholar
• Brand, M., J. G. Moggs, M. Oulad-Abdelghani, F. Lejeune, F. J. Dilworth, J. Stevenin, G. Almouzni, and L. Tora. 2001. UV-damaged DNA-binding protein in the TFTC complex links DNA damage recognition to nucleosome acetylation. EMBO J. 20: 3187–3196.
   PubMed Web of Science ®Google Scholar
• Brand, M., K. Yamamoto, A. Staub, and L. Tora. 1999. Identification of TATA-binding protein-free TAFII-containing complex subunits suggests a role in nucleosome acetylation and signal transduction. J. Biol. Chem. 274: 18285–18289.
   PubMedGoogle Scholar
• Brownell, J. E., J. Zhou, T. Ranalli, R. Kobayashi, D. G. Edmondson, S. Y. Roth, and C. D. Allis. 1996. Tetrahymena histone acetyltransferase A: a transcriptional co-activator linking gene expression to histone acetylation. Cell 84: 843–851.
   PubMed Web of Science ®Google Scholar
• Burns, L. G., and C. L. Peterson. 1997. The yeast SWI-SNF complex facilitates binding of a transcriptional activator to nucleosomal sites in vivo. Mol. Cell. Biol. 17: 4811–4819.
   PubMedGoogle Scholar
• Candau, R., and S. L. Berger. 1996. Structural and functional analysis of yeast putative adaptors: evidence for an adaptor complex in vivo. J. Biol. Chem. 271: 5237–5345.
   PubMedGoogle Scholar
• Candau, R., P. A. Moore, L. Wang, N. Barlev, C. Y. Ying, C. A. Rosen, and S. L. Berger. 1996. Identification of human proteins functionally conserved with the yeast putative adaptors ADA2 and GCN5. Mol. Cell. Biol. 16: 593–602.
   PubMedGoogle Scholar
• Chi, T. H., M. Wan, K. Zhao, I. Taniuchi, L. Chen, D. R. Littman, and G. R. Crabtree. 2002. Reciprocal regulation of CD4/CD8 expression by SWI/SNF-like BAF complexes. Nature 418: 195–199.
   PubMed Web of Science ®Google Scholar
• Chiba, H., M. Muramatsu, A. Nomoto, and H. Kato. 1994. Two human homologues of Saccharomyces cerevisiae SWI2/SNF2 and Drosophila brahma are transcriptional coactivators cooperating with the estrogen receptor and the retinoic acid receptor. Nucleic Acids Res. 22: 1815–1820.
   PubMed Web of Science ®Google Scholar
• Eberhard, D., and M. Busslinger. 1999. The partial homeodomain of the transcription factor Pax-5 (BSAP) is an interaction motif for the retinoblastoma and TATA-binding proteins. Cancer Res. 59: 1716s–1725s.
   PubMedGoogle Scholar
• Eberhard, D., G. Jimenez, B. Heavey, and M. Busslinger. 2000. Transcriptional repression by Pax5 (BSAP) through interaction with corepressors of the Groucho family. EMBO J. 19: 2292–2303.
   PubMed Web of Science ®Google Scholar
• Emelyanov, A. V., C. R. Kovac, M. A. Sepulveda, and B. K. Birshtein. 2002. The interaction of Pax5 (BSAP) with Daxx can result in transcriptional activation in B cells. J. Biol. Chem. 277: 11156–11164.
   PubMedGoogle Scholar
• Forsberg, E. C., L. T. Lam, X. J. Yang, Y. Nakatani, and E. H. Bresnick. 1997. Human histone acetyltransferase GCN5 exists in a stable macromolecular complex lacking the adapter ADA2. Biochemistry 36: 15918–15924.
   PubMedGoogle Scholar
• Grant, P. A., L. Duggan, J. Côté, S. M. Roberts, J. E. Brownell, R. Candau, R. Ohba, T. Owen-Hughes, C. D. Allis, F. Winston, S. L. Berger, and J. L. Workman. 1997. Yeast Gcn5 functions in two multisubunit complexes to acetylate nucleosomal histones: characterization of an Ada complex and the SAGA (Spt/Ada) complex. Genes Dev. 11: 1640–1650.
   PubMed Web of Science ®Google Scholar
• Grant, P. A., D. Schieltz, M. G. Pray-Grant, D. J. Steger, J. C. Reese, J. R. Yates III, and J. L. Workman. 1998. A subset of TAFIIs are integral components of the SAGA complex required for nucleosome acetylation and transcription stimulation. Cell 94: 45–53.
   PubMedGoogle Scholar
• Grant, P. A., D. Schieltz, M. G. Pray-Grant, J. R. Yates, and J. L. Workman. 1998. The ATM-related cofactor Tra1 is a component of the purified SAGA complex. Mol. Cell 2: 863–867.
   PubMed Web of Science ®Google Scholar
• Grant, P. A., D. E. Sterner, L. J. Duggan, J. L. Workman, and S. L. Berger. 1998. The SAGA unfolds: convergence of transcription regulators in chromatin-modifying complexes. Trends Cell Biol. 8: 193–197.
   PubMed Web of Science ®Google Scholar
• Gregory, P. D., K. Wagner, and W. Horz. 2001. Histone acetylation and chromatin remodeling. Exp. Cell Res. 265: 195–202.
   PubMed Web of Science ®Google Scholar
• Horiuchi, J., N. Silverman, G. A. Marcus, and L. Guarente. 1995. ADA3, a putative transcriptional adaptor, consists of two separable domains and interacts with ADA2 and GCN5 in a trimeric complex. Mol. Cell. Biol. 15: 1203–1209.
   PubMed Web of Science ®Google Scholar
• Jiang, H., H. Lu, R. L. Schiltz, C. A. Pise-Masison, V. V. Ogryzko, Y. Nakatani, and J. N. Brady. 1999. PCAF interacts with tax and stimulates tax transactivation in a histone acetyltransferase-independent manner. Mol. Cell. Biol. 19: 8136–8145.
   PubMed Web of Science ®Google Scholar
• Martinez, E., T. K. Kundu, J. Fu, and R. G. Roeder. 1998. A human SPT3-TAFII31-GCN5-L acetylase complex distinct from transcription factor IID. J. Biol. Chem. 273: 23781–23785.
   PubMed Web of Science ®Google Scholar
• Martinez, E., V. B. Palhan, A. Tjernberg, E. S. Lymar, A. M. Gamper, T. K. Kundu, B. T. Chait, and R. G. Roeder. 2001. Human STAGA complex is a chromatin-acetylating transcription coactivator that interacts with pre-mRNA splicing and DNA damage-binding factors in vivo. Mol. Cell. Biol. 21: 6782–6795.
   PubMed Web of Science ®Google Scholar
• Massari, M. E., P. A. Grant, M. G. Pray-Grant, S. L. Berger, J. L. Workman, and C. Murre. 1999. A conserved motif present in a class of helix-loop-helix proteins activates transcription by direct recruitment of the SAGA complex. Mol. Cell 4: 63–73.
   PubMed Web of Science ®Google Scholar
• McMahon, S. B., H. A. Van Buskirk, K. A. Dugan, T. D. Copeland, and M. D. Cole. 1998. The novel ATM-related protein TRRAP is an essential cofactor for the c-Myc and E2F oncoproteins. Cell 94: 363–374.
   PubMed Web of Science ®Google Scholar
• Muchardt, C., and M. Yaniv. 1993. A human homologue of Saccharomyces cerevisiae SNF2/SWI2 and Drosophila brm genes potentiates transcriptional activation by the glucocorticoid receptor. EMBO J. 12: 4279–4290.
   PubMed Web of Science ®Google Scholar
• Muchardt, C., and M. Yaniv. 2001. When the SWI/SNF complex remodels. the cell cycle. Oncogene 20: 3067–3075.
   PubMedGoogle Scholar
• Neely, K. E., A. H. Hassan, C. E. Brown, L. Howe, and J. L. Workman. 2002. Transcription activator interactions with multiple SWI/SNF subunits. Mol. Cell. Biol. 22: 1615–1625.
   PubMed Web of Science ®Google Scholar
• Nutt, S. L., A. M. Morrison, P. Dorfler, A. Rolink, and M. Busslinger. 1998. Identification of BSAP (Pax-5) target genes in early B-cell development by loss- and gain-of-function experiments. EMBO J. 17: 2319–2333.
   PubMed Web of Science ®Google Scholar
• Nutt, S. L., C. Thevenin, and M. Busslinger. 1997. Essential functions of Pax-5 (BSAP) in pro-B cell development. Immunobiology 198: 227–235.
   PubMedGoogle Scholar
• Ogryzko, V. V., T. Kotani, X. Zhang, R. L. Schiltz, T. Howard, X.-J. Yang, B. H. Howard, J. Qin, and Y. Nakatani. 1998. Histone-like TAFs within the PCAF histone acetylase complex. Cell 94: 35–44.
   PubMedGoogle Scholar
• Pollard, K. J., and C. L. Peterson. 1998. Chromatin remodeling: a marriage between two families? Bioessays 20: 771–780.
   PubMedGoogle Scholar
• Puri, P. L., V. Sartorelli, X. J. Yang, Y. Hamamori, V. V. Ogryzko, B. H. Howard, L. Kedes, J. Y. Wang, A. Graessmann, Y. Nakatani, and M. Levrero. 1997. Differential roles of p300 and PCAF acetyltransferases in muscle differentiation. Mol. Cell 1: 35–45.
   PubMed Web of Science ®Google Scholar
• Roberts, S. M., and F. Winston. 1997. Essential functional interactions of SAGA, a Saccharomyces cerevisiae complex of Spt, Ada, and Gcn5 proteins, with the Snf/Swi and Srb/mediator complexes. Genetics 147: 451–465.
   PubMedGoogle Scholar
• Saleh, A., V. Lang, R. Cook, and C. J. Brandl. 1997. Identification of native complexes containing the yeast coactivator/repressor proteins NGG1/ADA3 and ADA2. J. Biol. Chem. 272: 5571–5578.
   PubMed Web of Science ®Google Scholar
• Saleh, A., D. Schieltz, N. Ting, S. B. McMahon, D. W. Litchfield, J. R. Yates III, S. P. Lees-Miller, M. D. Cole, and C. J. Brandl. 1998. Tra1p is a component of the yeast Ada-Spt transcriptional regulatory complexes. J. Biol. Chem. 273: 26559–26565.
   PubMedGoogle Scholar
• Schnitzler, G., S. Sif, and R. E. Kingston. 1998. Human SWI/SNF interconverts a nucleosome between its base state and a stable remodeled state. Cell 94: 17–27.
   PubMed Web of Science ®Google Scholar
• Silverman, N., J. Agapite, and L. Guarente. 1994. Yeast ADA2 protein binds to the VP16 protein activation domain and activates transcription. Proc. Natl. Acad. Sci. USA 91: 11665–11668.
   PubMedGoogle Scholar
• Singh, M., and B. K. Birshtein. 1996. Concerted repression of an immunoglobulin heavy-chain enhancer, 3′ alpha E(hs1,2). Proc. Natl. Acad. Sci. USA 93: 4392–4397.
   PubMedGoogle Scholar
• Singh, M., and B. K. Birshtein. 1993. NF-HB (BSAP) is a repressor of the murine immunoglobulin heavy-chain 3′ alpha enhancer at early stages of B-cell differentiation. Mol. Cell. Biol. 13: 3611–3622.
   PubMed Web of Science ®Google Scholar
• Smith, E. R., J. M. Belote, R. L. Schiltz, X. J. Yang, P. A. Moore, S. L. Berger, Y. Nakatani, and C. D. Allis. 1998. Cloning of Drosophila GCN5: conserved features among metazoan GCN5 family members. Nucleic Acids Res. 26: 2948–2954.
   PubMedGoogle Scholar
• Sterner, D. E., X. Wang, M. H. Bloom, G. M. Simon, and S. L. Berger. 2002. The SANT domain of Ada2 is required for normal acetylation of histones by the yeast SAGA complex. J. Biol. Chem. 277: 8178–8186.
   PubMedGoogle Scholar
• Stockinger, E. J., Y. Mao, M. K. Regier, S. J. Triezenberg, and M. F. Thomashow. 2001. Transcriptional adaptor and histone acetyltransferase proteins in Arabidopsis and their interactions with CBF1, a transcriptional activator involved in cold-regulated gene expression. Nucleic Acids Res. 29: 1524–1533.
   PubMed Web of Science ®Google Scholar
• Tanaka, Y., I. Naruse, T. Maekawa, H. Masuya, T. Shiroishi, and S. Ishii. 1997. Abnormal skeletal patterning in embryos lacking a single Cbp allele: a partial similarity with Rubinstein-Taybi syndrome. Proc. Natl. Acad. Sci. USA 94: 10215–10220.
   PubMed Web of Science ®Google Scholar
• Thomas, J. O., and A. A. Travers. 2001. HMG1 and -2, and related “architectural” DNA-binding proteins. Trends Biochem. Sci. 26: 167–174.
   PubMed Web of Science ®Google Scholar
• Trouche, D., C. Le Chalony, C. Muchardt, M. Yaniv, and T. Kouzarides. 1997. RB and hbrm cooperate to repress the activation functions of E2F1. Proc. Natl. Acad. Sci. USA 94: 11268–11273.
   PubMed Web of Science ®Google Scholar
• Vassilev, A., J. Yamauchi, T. Kotani, C. Prives, M. L. Avantaggiati, J. Qin, and Y. Nakatani. 1998. The 400-kDa subunit of the PCAF histone acetylase complex belongs to the ATM superfamily. Mol. Cell 2: 869–875.
   PubMedGoogle Scholar
• Vojtek, A., S. Hollenberg, and J. Cooper. 1993. Mammalian Ras interacts directly with the serine/threonine kinase Raf. Cell 74: 205–214.
   PubMed Web of Science ®Google Scholar
• Wang, L., C. Mizzen, C. Ying, R. Candau, N. Barlev, J. Brownell, C. D. Allis, and S. Berger. 1997. Histone acetyltransferase activity is conserved between yeast and human GCN5 and required for complementation of growth and transcriptional activation. Mol. Cell. Biol. 17: 519–527.
   PubMedGoogle Scholar
• Wang, W., T. Chi, Y. Xue, S. Zhou, A. Kuo, and G. R. Crabtree. 1998. Architectural DNA binding by a high-mobility-group/kinesin-like subunit in mammalian SWI/SNF-related complexes. Proc. Natl. Acad. Sci. USA 95: 492–498.
   PubMedGoogle Scholar
• Wang, W., J. Cote, Y. Xue, S. Zhou, P. A. Khavari, S. R. Biggar, C. Muchardt, G. V. Kaplana, S. P. Goff, M. Yaniv, J. L. Workman, and G. R. Crabtree. 1996. Purification and biochemical heterogeneity of the mammalian SWI/SNF complex. EMBO J. 15: 5370–5382.
   PubMed Web of Science ®Google Scholar
• Wieczorek, E., M. Brand, X. Jacq, and L. Tora. 1998. Function of TAF(II)-containing complex without TBP in transcription by RNA polymerase II. Nature 393: 187–191.
   PubMedGoogle Scholar
• Winston, F., and M. Carlson. 1992. Yeast SNF/SWI transcriptional activators and the SPT/SIN chromatin connection. Trends Genet. 8: 387–391.
   PubMed Web of Science ®Google Scholar
• Xu, W., D. G. Edmondson, Y. A. Evrard, M. Wakamiya, R. R. Behringer, and S. Y. Roth. 2000. Loss of Gcn5l2 leads to increased apoptosis and mesodermal defects during mouse development. Nat. Genet. 26: 229–232.
   PubMedGoogle Scholar
• Xu, W., D. G. Edmondson, and S. Y. Roth. 1998. Mammalian GCN5 and P/CAF acetyltransferases have homologous amino-terminal domains important for recognition of nucleosomal substrates. Mol. Cell. Biol. 18: 5659–5669.
   PubMedGoogle Scholar
• Yamauchi, T., J. Yamauchi, T. Kuwata, T. Tamura, T. Yamashita, N. Bae, H. Westphal, K. Ozato, and Y. Nakatani. 2000. Distinct but overlapping roles of histone acetylase PCAF and of the closely related PCAF-B/GCN5 in mouse embryogenesis. Proc. Natl. Acad. Sci. USA 97: 11303–11306.
   PubMedGoogle Scholar
• Yanagisawa, J., H. Kitagawa, M. Yanagida, O. Wada, S. Ogawa, M. Nakagomi, H. Oishi, Y. Yamamoto, H. Nagasawa, S. B. McMahon, M. D. Cole, L. Tora, N. Takahashi, and S. Kato. 2002. Nuclear receptor function requires a TFTC-type histone acetyl transferase complex. Mol. Cell 9: 553–562.
   PubMed Web of Science ®Google Scholar
• Yang, X.-J., V. V. Ogryzko, J. Nishikawa, B. H. Howard, and Y. Nakatani. 1996. A p300/CBP-associated factor that competes with the adenoviral E1A oncoprotein. Nature 382: 319–324.
   PubMed Web of Science ®Google Scholar
• Yao, T. P., S. P. Oh, M. Fuchs, N. D. Zhou, L. E. Ch'ng, D. Newsome, R. T. Bronson, E. Li, D. M. Livingston, and R. Eckner. 1998. Gene dosage-dependent embryonic development and proliferation defects in mice lacking the transcriptional integrator p300. Cell 93: 361–372.
   PubMed Web of Science ®Google Scholar