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Cell Growth and Development

Nckβ Interacts with Tyrosine-Phosphorylated Disabled 1 and Redistributes in Reelin-Stimulated Neurons

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Pages 7210-7221 | Received 23 Jan 2003, Accepted 10 Jul 2003, Published online: 27 Mar 2023

REFERENCES

  • Arnaud, L., B. A. Ballif, E. Fürster, and J. A. Cooper. 2003. Fyn tyrosine kinase is a critical regulator of Disabled-1 during brain development. Curr. Biol. 13: 9–17.
  • Beffert, U., G. Morfini, H. H. Bock, H. Reyna, S. T. Brady, and J. Herz. 2002. Reelin-mediated signaling locally regulates protein kinase B/Akt and glycogen synthase kinase 3beta. J. Biol. Chem. 277: 49958–49964.
  • Bock, H. H., and J. Herz. 2003. Reelin activates Src family tyrosine kinases in neurons. Curr. Biol. 13: 18–26.
  • Brand, A. H., and N. Perrimon. 1993. Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118: 401–415.
  • Buday, L., L. Wunderlich, and P. Tamas. 2002. The Nck family of adapter proteins: regulators of actin cytoskeleton. Cell Signal. 14: 723–731.
  • Carlberg, K., and L. R. Rohrschneider. 1997. Characterization of a novel tyrosine-phosphorylated 100-kDa protein that binds to SHP-2 and phosphatidylinositol 3′-kinase in myeloid cells. J. Biol. Chem. 272: 15943–15950.
  • Chen, M., H. She, A. Kim, D. T. Woodley, and W. Li. 2000. Nckbeta adapter regulates actin polymerization in NIH 3T3 fibroblasts in response to platelet-derived growth factor bb. Mol. Cell. Biol. 20: 7867–7880.
  • Cowan, C. A., and M. Henkemeyer. 2001. The SH2/SH3 adaptor Grb4 transduces B-ephrin reverse signals. Nature 413: 174–179.
  • D'Arcangelo, G., R. Homayouni, L. Keshvara, D. S. Rice, M. Sheldon, and T. Curran. 1999. Reelin is a ligand for lipoprotein receptors. Neuron 24: 471–479.
  • D'Arcangelo, G., G. G. Miao, S. C. Chen, H. D. Soares, J. I. Morgan, and T. Curran. 1995. A protein related to extracellular matrix proteins deleted in the mouse mutant reeler. Nature 374: 719–723.
  • D'Arcangelo, G., G. G. Miao, and T. Curran. 1996. Detection of the reelin breakpoint in reeler mice. Brain Res. Mol. Brain Res. 39: 234–236.
  • D'Arcangelo, G., K. Nakajima, T. Miyata, M. Ogawa, K. Mikoshiba, and T. Curran. 1997. Reelin is a secreted glycoprotein recognized by the CR-50 monoclonal antibody. J. Neurosci. 17: 23–31.
  • Desai, C. J., P. A. Garrity, H. Keshishian, S. L. Zipursky, and K. Zinn. 1999. The Drosophila SH2-SH3 adapter protein Dock is expressed in embryonic axons and facilitates synapse formation by the RP3 motoneuron. Development 126: 1527–1535.
  • Garrity, P. A., Y. Rao, I. Salecker, J. McGlade, T. Pawson, and S. L. Zipursky. 1996. Drosophila photoreceptor axon guidance and targeting requires the dreadlocks SH2/SH3 adapter protein. Cell 85: 639–650.
  • Goldowitz, D., R. C. Cushing, E. Laywell, G. D'Arcangelo, M. Sheldon, H. O. Sweet, M. Davisson, D. Steindler, and T. Curran. 1997. Cerebellar disorganization characteristic of reeler in scrambler mutant mice despite presence of reelin. J. Neurosci. 17: 8767–8777.
  • Gupta, A., L. H. Tsai, and A. Wynshaw-Boris. 2002. Life is a journey: a genetic look at neocortical development. Nat. Rev. Genet. 3: 342–355.
  • Hammond, V., B. Howell, L. Godinho, and S.-S. Tan. 2001. Disabled-1 functions cell autonomously during radial migration and cortical layering of pyramidal neurons. J. Neurosci. 21: 8798–8808.
  • Hay, B. A., T. Wolff, and G. M. Rubin. 1994. Expression of baculovirus P35 prevents cell death in Drosophila. Development 120: 2121–2129.
  • Herz, J. 2001. The LDL receptor gene family: (un)expected signal transducers in the brain. Neuron 29: 571–581.
  • Hiesberger, T., M. Trommsdorff, B. W. Howell, A. Goffinet, M. C. Mumby, J. A. Cooper, and J. Herz. 1999. Direct binding of Reelin to VLDL receptor and ApoE receptor 2 induces tyrosine phosphorylation of disabled-1 and modulates tau phosphorylation. Neuron 24: 481–489.
  • Hing, H., J. Xiao, N. Harden, L. Lim, and S. L. Zipursky. 1999. Pak functions downstream of Dock to regulate photoreceptor axon guidance in Drosophila. Cell 97: 853–863.
  • Homayouni, R., and T. Curran. 2000. Cdk5 gets into sticky situations. Curr. Biol. 10: R331–R334.
  • Homayouni, R., D. S. Rice, and T. Curran. 2001. Disabled-1 interacts with a novel developmentally regulated protocadherin. Biochem. Biophys. Res. Commun. 289: 539–547.
  • Homayouni, R., D. S. Rice, M. Sheldon, and T. Curran. 1999. Disabled-1 binds to the cytoplasmic domain of amyloid precursor-like protein 1. J. Neurosci. 19: 7507–7515.
  • Howell, B. W., F. B. Gertler, and J. A. Cooper. 1997. Mouse disabled (mDab1): a Src binding protein implicated in neuronal development. EMBO J. 16: 1165–1175.
  • Howell, B. W., R. Hawkes, P. Soriano, and J. A. Cooper. 1997. Neuronal position in the developing brain is regulated by mouse disabled-1. Nature 389: 733–737.
  • Howell, B. W., T. M. Herrick, and J. A. Cooper. 1999. Reelin-induced tyrosine phosphorylation of disabled 1 during neuronal positioning. Genes Dev. 13: 643–648.
  • Howell, B. W., T. M. Herrick, J. D. Hildebrand, Y. Zhang, and J. A. Cooper. 2000. Dab1 tyrosine phosphorylation sites relay positional signals during mouse brain development. Curr. Biol. 10: 877–885.
  • Howell, B. W., L. M. Lanier, R. Frank, F. B. Gertler, and J. A. Cooper. 1999. The disabled 1 phosphotyrosine-binding domain binds to the internalization signals of transmembrane glycoproteins and to phospholipids. Mol. Cell. Biol. 19: 5179–5188.
  • Kamal, A., G. B. Stokin, Z. Yang, C. H. Xia, and L. S. Goldstein. 2000. Axonal transport of amyloid precursor protein is mediated by direct binding to the kinesin light chain subunit of kinesin-I. Neuron 28: 449–459.
  • Keegan, K., and J. A. Cooper. 1996. Use of the two hybrid system to detect the association of the protein-tyrosine-phosphatase, SHPTP2, with another SH2-containing protein, Grb7. Oncogene 12: 1537–1544.
  • Keshvara, L., D. Benhayon, S. Magdaleno, and T. Curran. 2001. Identification of reelin-induced sites of tyrosyl phosphorylation on disabled 1. J. Biol. Chem. 276: 16008–16014.
  • Li, W., J. Fan, and D. T. Woodley. 2001. Nck/Dock: an adapter between cell surface receptors and the actin cytoskeleton. Oncogene 20: 6403–6417.
  • Li, W., and H. She. 2000. The SH2 and SH3 adapter Nck: a two-gene family and a linker between tyrosine kinases and multiple signaling networks. Histol. Histopathol. 15: 947–955.
  • Lioubin, M. N., P. A. Algate, S. Tsai, K. Carlberg, R. Aebersold, and L. R. Rohrschneider. 1996. p150Ship, A signal transduction molecule with inositol polyphosphate-5-phosphatase activity. Genes Dev. 10: 1084–1095.
  • Maricich, S. M., E. C. Gilmore, and K. Herrup. 2001. The role of tangential migration in the establishment of mammalian cortex. Neuron 31: 175–178.
  • Nikolic, M., M. M. Chou, W. Lu, B. J. Mayer, and L. H. Tsai. 1998. The p35/Cdk5 kinase is a neuron-specific Rac effector that inhibits Pak1 activity. Nature 395: 194–198.
  • Ogawa, M., T. Miyata, K. Nakajima, K. Yagyu, M. Seike, K. Ikenaka, H. Yamamoto, and K. Mikoshiba. 1995. The reeler gene-associated antigen on Cajal-Retzius neurons is a crucial molecule for laminar organization of cortical neurons. Neuron 14: 899–912.
  • Ohshima, T., M. Ogawa, Veeranna, M. Hirasawa, G. Longenecker, K. Ishiguro, H. C. Pant, R. O. Brady, A. B. Kulkarni, and K. Mikoshiba. 2001. Synergistic contributions of cyclin-dependant kinase 5/p35 and Reelin/Dab1 to the positioning of cortical neurons in the developing mouse brain. Proc. Natl. Acad. Sci. USA 98: 2764–2769.
  • Rice, D. S., and T. Curran. 2001. Role of the reelin signaling pathway in central nervous system development. Annu. Rev. Neurosci. 24: 1005–1039.
  • Rice, D. S., M. Sheldon, G. D'Arcangelo, K. Nakajima, D. Goldowitz, and T. Curran. 1998. Disabled-1 acts downstream of Reelin in a signaling pathway that controls laminar organization in the mammalian brain. Development 125: 3719–3729.
  • Ross, M. E., and C. A. Walsh. 2001. Human brain malformations and their lessons for neuronal migration. Annu. Rev. Neurosci. 24: 1041–1070.
  • Schneider, C., R. A. Newman, D. R. Sutherland, U. Asser, and M. F. Greaves. 1982. A one-step purification of membrane proteins with a high efficiency immunomatrix. J. Biol. Chem. 257: 10766–10769.
  • Sheldon, M., D. S. Rice, G. D'Arcangelo, H. Yoneshima, K. Nakajima, K. Mikoshiba, B. W. Howell, J. A. Cooper, D. Goldowitz, and T. Curran. 1997. Scrambler and yotari disrupt the disabled gene and produce a reeler-like phenotype in mice. Nature 389: 730–733.
  • Sweet, H. O., R. T. Bronson, K. R. Johnson, S. A. Cook, and M. T. Davisson. 1996. Scrambler, a new neurological mutation of the mouse with abnormalities of neuronal migration. Mamm. Genome. 7: 798–802.
  • Trommsdorff, M., J. P. Borg, B. Margolis, and J. Herz. 1998. Interaction of cytosolic adaptor proteins with neuronal apolipoprotein E receptors and the amyloid precursor protein. J. Biol. Chem. 273: 33556–33560.
  • Trommsdorff, M., M. Gotthardt, T. Hiesberger, J. Shelton, W. Stockinger, J. Nimpf, R. E. Hammer, J. A. Richardson, and J. Herz. 1999. Reeler/Disabled-like disruption of neuronal migraton in knockout mice lacking the VLDL receptor and ApoE receptor-2. Cell 689–701.
  • Tu, Y., D. F. Kucik, and C. Wu. 2001. Identification and kinetic analysis of the interaction between Nck-2 and DOCK180. FEBS Lett. 491: 193–199.
  • Verhey, K. J., D. Meyer, R. Deehan, J. Blenis, B. J. Schnapp, T. A. Rapoport, and B. Margolis. 2001. Cargo of kinesin identified as Jun-interacting protein scaffolding proteins and associated signaling molecules. J. Cell Biol. 152: 959–970.
  • Vojtek, A. B., and S. M. Hollenberg. 1995. Ras-Raf interaction: two-hybrid analysis. Methods Enzymol. 255: 331–342.
  • Ware, M. L., J. W. Fox, J. L. Gonzalez, N. M. Davis, C. Lambert, C. J. Russo, S. C. Chua Jr., A. M. Goffinet, and C. A. Walsh. 1997. Aberrant splicing of a mouse disabled homolog, mdab1, in the scrambler mouse. Neuron 19: 239–249.
  • Yip, J. W., Y. P. Yip, K. Nakajima, and C. Capriotti. 2000. Reelin controls position of autonomic neurons in the spinal cord. Proc. Natl. Acad. Sci. USA 97: 8612–8616.

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