Molecular and Cellular Biology, Volume 23, Issue 20 (2003)

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Molecular and Cellular Biology, Volume 23, Issue 20 (2003)

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Gene Expression

Article
Influence of the RNA-Binding Protein HuR in pVHL-Regulated p53 Expression in Renal Carcinoma Cells
Stefanie Galbán, Jennifer L. Martindale, Krystyna Mazan-Mamczarz, Isabel López de Silanes, Jinshui Fan, Wengong Wang, Jochen Decker & Myriam Gorospe
Pages: 7083-7095
Published online: 27 Mar 2023
AbstractforInfluence of the RNA-Binding Protein HuR in pVHL-Regulated p53 Expression in Renal Carcinoma Cells | Full Text | References | PDF (744.3 KB)
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Article
Steroid Receptor RNA Activator Stimulates Proliferation as Well as Apoptosis In Vivo
Rainer B. Lanz, Steven S. Chua, Niall Barron, Bettina M. Süder, Francesco DeMayo & Bert W. O'Malley
Pages: 7163-7176
Published online: 27 Mar 2023
AbstractforSteroid Receptor RNA Activator Stimulates Proliferation as Well as Apoptosis In Vivo | Full Text | References | PDF (1.5 MB)
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Article
Stabilization of Urokinase and Urokinase Receptor mRNAs by HuR Is Linked to Its Cytoplasmic Accumulation Induced by Activated Mitogen-Activated Protein Kinase-Activated Protein Kinase 2
Hoanh Tran, Fabienne Maurer & Yoshikuni Nagamine
Pages: 7177-7188
Published online: 27 Mar 2023
AbstractforStabilization of Urokinase and Urokinase Receptor mRNAs by HuR Is Linked to Its Cytoplasmic Accumulation Induced by Activated Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 | Full Text | References | PDF (824.2 KB)
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Article
Rds3p Is Required for Stable U2 snRNP Recruitment to the Splicing Apparatus
Qiang Wang & Brian C. Rymond
Pages: 7339-7349
Published online: 27 Mar 2023
AbstractforRds3p Is Required for Stable U2 snRNP Recruitment to the Splicing Apparatus | Full Text | References | PDF (393.6 KB)
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Article
Nuclear Pnn/DRS Protein Binds to Spliced mRNPs and Participates in mRNA Processing and Export via Interaction with RNPS1
Chin Li, Ru-Inn Lin, Ming-Chih Lai, Pin Ouyang & Woan-Yuh Tarn
Pages: 7363-7376
Published online: 27 Mar 2023
AbstractforNuclear Pnn/DRS Protein Binds to Spliced mRNPs and Participates in mRNA Processing and Export via Interaction with RNPS1 | Full Text | References | PDF (698.2 KB)
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Article
c-Fos Proto-Oncoprotein Is Degraded by the Proteasome Independently of Its Own Ubiquitinylation In Vivo
Guillaume Bossis, Patrizia Ferrara, Claire Acquaviva, Isabelle Jariel-Encontre & Marc Piechaczyk
Pages: 7425-7436
Published online: 27 Mar 2023
Abstractforc-Fos Proto-Oncoprotein Is Degraded by the Proteasome Independently of Its Own Ubiquitinylation In Vivo | Full Text | References | PDF (556.9 KB)
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Transcriptional Regulation

Article
14-3-3σ Positively Regulates p53 and Suppresses Tumor Growth
Heng-Yin Yang, Yu-Ye Wen, Chih-Hsin Chen, Guillermina Lozano & Mong-Hong Lee
Pages: 7096-7107
Published online: 27 Mar 2023
Abstractfor14-3-3σ Positively Regulates p53 and Suppresses Tumor Growth | Full Text | References | PDF (556.5 KB)
  • 147 Views
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Article
The Cochaperone Bag-1L Enhances Androgen Receptor Action via Interaction with the NH2-Terminal Region of the Receptor
Liubov Shatkina, Sigrun Mink, Hermann Rogatsch, Helmut Klocker, Gernot Langer, Andrea Nestl & Andrew C. B. Cato
Pages: 7189-7197
Published online: 27 Mar 2023
AbstractforThe Cochaperone Bag-1L Enhances Androgen Receptor Action via Interaction with the NH2-Terminal Region of the Receptor | Full Text | References | PDF (455.3 KB)
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Article
Core Promoter Elements and TAFs Contribute to the Diversity of Transcriptional Activation in Vertebrates
Zheng Chen & James L. Manley
Pages: 7350-7362
Published online: 27 Mar 2023
AbstractforCore Promoter Elements and TAFs Contribute to the Diversity of Transcriptional Activation in Vertebrates | Full Text | References | PDF (363.8 KB)
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Cell Growth and Development

Article
Daxx Silencing Sensitizes Cells to Multiple Apoptotic Pathways
Liuh-Yow Chen & J. Don Chen
Pages: 7108-7121
Published online: 27 Mar 2023
AbstractforDaxx Silencing Sensitizes Cells to Multiple Apoptotic Pathways | Full Text | References | PDF (860.5 KB)
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Article
Nrf2 Is a Direct PERK Substrate and Effector of PERK-Dependent Cell Survival
Sara B. Cullinan, Donna Zhang, Mark Hannink, Edward Arvisais, Randal J. Kaufman & J. Alan Diehl
Pages: 7198-7209
Published online: 27 Mar 2023
AbstractforNrf2 Is a Direct PERK Substrate and Effector of PERK-Dependent Cell Survival | Full Text | References | PDF (693.4 KB)
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Article
Nckβ Interacts with Tyrosine-Phosphorylated Disabled 1 and Redistributes in Reelin-Stimulated Neurons
Albéna Pramatarova, Pawel G. Ochalski, Kelian Chen, Andrea Gropman, Sage Myers, Kyung-Tai Min & Brian W. Howell
Pages: 7210-7221
Published online: 27 Mar 2023
AbstractforNckβ Interacts with Tyrosine-Phosphorylated Disabled 1 and Redistributes in Reelin-Stimulated Neurons | Full Text | References | PDF (1,010.2 KB)
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Article
Targeted Elimination of Peroxisome Proliferator-Activated Receptor γ in β Cells Leads to Abnormalities in Islet Mass without Compromising Glucose Homeostasis
Evan D. Rosen, Rohit N. Kulkarni, Pasha Sarraf, Umut Ozcan, Terumasa Okada, Chung-Hsin Hsu, Daniel Eisenman, Mark A. Magnuson, Frank J. Gonzalez, C. Ronald Kahn & Bruce M. Spiegelman
Pages: 7222-7229
Published online: 27 Mar 2023
AbstractforTargeted Elimination of Peroxisome Proliferator-Activated Receptor γ in β Cells Leads to Abnormalities in Islet Mass without Compromising Glucose Homeostasis | Full Text | References | PDF (299 KB)
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Article
Myostatin Signals through a Transforming Growth Factor β-Like Signaling Pathway To Block Adipogenesis
A. Rebbapragada, H. Benchabane, J. L. Wrana, A. J. Celeste & L. Attisano
Pages: 7230-7242
Published online: 27 Mar 2023
AbstractforMyostatin Signals through a Transforming Growth Factor β-Like Signaling Pathway To Block Adipogenesis | Full Text | References | PDF (981.8 KB)
  • 105 Views
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Article
Prox1 Is a Novel Coregulator of Ff1b and Is Involved in the Embryonic Development of the Zebra Fish Interrenal Primordium
Yi-Wen Liu, Wei Gao, Hui-Ling Teh, Jee-Hian Tan & Woon-Khiong Chan
Pages: 7243-7255
Published online: 27 Mar 2023
AbstractforProx1 Is a Novel Coregulator of Ff1b and Is Involved in the Embryonic Development of the Zebra Fish Interrenal Primordium | Full Text | References | PDF (1.6 MB)
  • 19 Views
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Article
c-Myc Augments Gamma Irradiation-Induced Apoptosis by Suppressing Bcl-XL
Kirsteen H. Maclean, Ulrich B. Keller, Carlos Rodriguez-Galindo, Jonas A. Nilsson & John L. Cleveland
Pages: 7256-7270
Published online: 27 Mar 2023
Abstractforc-Myc Augments Gamma Irradiation-Induced Apoptosis by Suppressing Bcl-XL | Full Text | References | PDF (996.5 KB)
  • 11 Views
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Article
p27Kip1 and p21Cip1 Are Not Required for the Formation of Active D Cyclin-cdk4 Complexes
Tapan K. Bagui, Subhra Mohapatra, Eric Haura & W. J. Pledger
Pages: 7285-7290
Published online: 27 Mar 2023
Abstractforp27Kip1 and p21Cip1 Are Not Required for the Formation of Active D Cyclin-cdk4 Complexes | Full Text | References | PDF (229 KB)
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Article
Distinct Rho GTPase Activities Regulate Epithelial Cell Localization of the Adhesion Molecule CEACAM1: Involvement of the CEACAM1 Transmembrane Domain
Bénédicte Fournès, Jennifer Farrah, Melanie Olson, Nathalie Lamarche-Vane & Nicole Beauchemin
Pages: 7291-7304
Published online: 27 Mar 2023
AbstractforDistinct Rho GTPase Activities Regulate Epithelial Cell Localization of the Adhesion Molecule CEACAM1: Involvement of the CEACAM1 Transmembrane Domain | Full Text | References | PDF (600.7 KB)
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Article
Degradation of Transcription Repressor ZBRK1 through the Ubiquitin-Proteasome Pathway Relieves Repression of Gadd45a upon DNA Damage
Jeanho Yun & Wen-Hwa Lee
Pages: 7305-7314
Published online: 27 Mar 2023
AbstractforDegradation of Transcription Repressor ZBRK1 through the Ubiquitin-Proteasome Pathway Relieves Repression of Gadd45a upon DNA Damage | Full Text | References | PDF (467.2 KB)
  • 12 Views
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Article
Akt-Directed Glucose Metabolism Can Prevent Bax Conformation Change and Promote Growth Factor-Independent Survival
Jeffrey C. Rathmell, Casey J. Fox, David R. Plas, Peter S. Hammerman, Ryan M. Cinalli & Craig B. Thompson
Pages: 7315-7328
Published online: 27 Mar 2023
AbstractforAkt-Directed Glucose Metabolism Can Prevent Bax Conformation Change and Promote Growth Factor-Independent Survival | Full Text | References | PDF (552.5 KB)
  • 178 Views
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Article
The COOH-Terminal Domain of Wild-Type Cot Regulates Its Stability and Kinase Specific Activity
Maria Luisa Gándara, Pilar López, Raquel Hernando, José G. Castaño & Susana Alemany
Pages: 7377-7390
Published online: 27 Mar 2023
AbstractforThe COOH-Terminal Domain of Wild-Type Cot Regulates Its Stability and Kinase Specific Activity | Full Text | References | PDF (639.5 KB)
  • 24 Views
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Article
Tyrosine Phosphorylation of Plakoglobin Causes Contrary Effects on Its Association with Desmosomes and Adherens Junction Components and Modulates β-Catenin-Mediated Transcription
Susana Miravet, José Piedra, Julio Castaño, Imma Raurell, Clara Francí, Mireia Duñach & Antonio García de Herreros
Pages: 7391-7402
Published online: 27 Mar 2023
AbstractforTyrosine Phosphorylation of Plakoglobin Causes Contrary Effects on Its Association with Desmosomes and Adherens Junction Components and Modulates β-Catenin-Mediated Transcription | Full Text | References | PDF (632.2 KB)
  • 24 Views
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Article
TOR Regulates the Subcellular Localization of Ime1, a Transcriptional Activator of Meiotic Development in Budding Yeast
Neus Colomina, Yuhui Liu, Martí Aldea & Eloi Garí
Pages: 7415-7424
Published online: 27 Mar 2023
AbstractforTOR Regulates the Subcellular Localization of Ime1, a Transcriptional Activator of Meiotic Development in Budding Yeast | Full Text | References | PDF (582.3 KB)
  • 13 Views
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Mammalian Genetic Models With Minimal Or Complex Phenotypes

Article
PAK4 Kinase Is Essential for Embryonic Viability and for Proper Neuronal Development
Jian Qu, Xiaofan Li, Bennet G. Novitch, Ye Zheng, Matthew Kohn, Jian-Ming Xie, Spencer Kozinn, Roderick Bronson, Amer A. Beg & Audrey Minden
Pages: 7122-7133
Published online: 27 Mar 2023
AbstractforPAK4 Kinase Is Essential for Embryonic Viability and for Proper Neuronal Development | Full Text | References | PDF (812.8 KB)
  • 69 Views
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Article
Targeted Disruption of the Gene for the PAK5 Kinase in Mice
Xiaofan Li & Audrey Minden
Pages: 7134-7142
Published online: 27 Mar 2023
AbstractforTargeted Disruption of the Gene for the PAK5 Kinase in Mice | Full Text | References | PDF (939.5 KB)
  • 9 Views
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Article
Role of Phospholipase C-L2, a Novel Phospholipase C-Like Protein That Lacks Lipase Activity, in B-Cell Receptor Signaling
Kei Takenaka, Kiyoko Fukami, Makiko Otsuki, Yoshikazu Nakamura, Yuki Kataoka, Mika Wada, Kohichiro Tsuji, Shin-Ichi Nishikawa, Nobuaki Yoshida & Tadaomi Takenawa
Pages: 7329-7338
Published online: 27 Mar 2023
AbstractforRole of Phospholipase C-L2, a Novel Phospholipase C-Like Protein That Lacks Lipase Activity, in B-Cell Receptor Signaling | Full Text | References | PDF (610.5 KB)
  • 28 Views
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Dna Dynamics and Chromosome Structure

Article
Molecular Basis for Expression of Common and Rare Fragile Sites
Eitan Zlotorynski, Ayelet Rahat, Jennifer Skaug, Neta Ben-Porat, Efrat Ozeri, Ruth Hershberg, Ayala Levi, Stephen W. Scherer, Hanah Margalit & Batsheva Kerem
Pages: 7143-7151
Published online: 27 Mar 2023
AbstractforMolecular Basis for Expression of Common and Rare Fragile Sites | Full Text | References | PDF (281.4 KB)
  • 70 Views
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Article
Processing of Double-Strand Breaks Is Involved in the Precise Excision of Paramecium Internal Eliminated Sequences
Ariane Gratias & Mireille Bétermier
Pages: 7152-7162
Published online: 27 Mar 2023
AbstractforProcessing of Double-Strand Breaks Is Involved in the Precise Excision of Paramecium Internal Eliminated Sequences | Full Text | References | PDF (568.5 KB)
  • 16 Views
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Nucleocytoplasmic Communication

Article
Sec13 Shuttles between the Nucleus and the Cytoplasm and Stably Interacts with Nup96 at the Nuclear Pore Complex
Jost Enninga, Agata Levay & Beatriz M. A. Fontoura
Pages: 7271-7284
Published online: 27 Mar 2023
AbstractforSec13 Shuttles between the Nucleus and the Cytoplasm and Stably Interacts with Nup96 at the Nuclear Pore Complex | Full Text | References | PDF (1.1 MB)
  • 150 Views
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Cell and Organelle Structure and Assembly

Article
The Yeast Nα-Acetyltransferase NatA Is Quantitatively Anchored to the Ribosome and Interacts with Nascent Polypeptides
Matthias Gautschi, Süren Just, Andrej Mun, Suzanne Ross, Peter Rücknagel, Yves Dubaquié, Ann Ehrenhofer-Murray & Sabine Rospert
Pages: 7403-7414
Published online: 27 Mar 2023
AbstractforThe Yeast Nα-Acetyltransferase NatA Is Quantitatively Anchored to the Ribosome and Interacts with Nascent Polypeptides | Full Text | References | PDF (591.6 KB)
  • 88 Views
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