The Papillomavirus E8^∧E2C Protein Represses DNA Replication from Extrachromosomal Origins

REFERENCES

• Adams, A. 1987. Replication of latent Epstein-Barr virus genomes in Raji cells. J. Virol. 61: 1743–1746.
   PubMed Web of Science ®Google Scholar
• Barsoum, J., S. S. Prakash, P. Han, and E. J. Androphy. 1992. Mechanism of action of the papillomavirus E2 repressor: repression in the absence of DNA binding. J. Virol. 66: 3941–3945.
   PubMedGoogle Scholar
• Bedell, M. A., J. B. Hudson, T. R. Golub, M. E. Turyk, M. Hosken, G. D. Wilbanks, and L. A. Laimins. 1991. Amplification of human papillomavirus genomes in vitro is dependent on epithelial differentiation. J. Virol. 65: 2254–2260.
   PubMed Web of Science ®Google Scholar
• Bouvard, V., A. Storey, D. Pim, and L. Banks. 1994. Characterization of the human papillomavirus E2 protein: evidence of trans-activation and trans-repression in cervical keratinocytes. EMBO J. 13: 5451–5459.
   PubMedGoogle Scholar
• Chaudhuri, B., H. Xu, I. Todorov, A. Dutta, and J. L. Yates. 2001. Human DNA replication initiation factors, ORC and MCM, associate with oriP of Epstein-Barr virus. Proc. Natl. Acad. Sci. USA 98: 10085–10089.
   PubMedGoogle Scholar
• Choe, J., P. Vaillancourt, A. Stenlund, and M. Botchan. 1989. Bovine papillomavirus type 1 encodes two forms of a transcriptional repressor: structural and functional analysis of new viral cDNAs. J. Virol. 63: 1743–1755.
   PubMed Web of Science ®Google Scholar
• Demeret, C., M. Le Moal, M. Yaniv, and F. Thierry. 1995. Control of HPV 18 DNA replication by cellular and viral transcription factors. Nucleic Acids Res. 23: 4777–4784.
   PubMedGoogle Scholar
• Dhar, S. K., K. Yoshida, Y. Machida, P. Khaira, B. Chaudhuri, J. A. Wohlschlegel, M. Leffak, J. Yates, and A. Dutta. 2001. Replication from oriP of Epstein-Barr virus requires human ORC and is inhibited by geminin. Cell 106: 287–296.
   PubMed Web of Science ®Google Scholar
• Frattini, M. G., and L. A. Laimins. 1994. The role of the E1 and E2 proteins in the replication of human papillomavirus type 31b. Virology 204: 799–804.
   PubMedGoogle Scholar
• Gilbert, D. M., and S. N. Cohen. 1987. Bovine papilloma virus plasmids replicate randomly in mouse fibroblasts throughout S phase of the cell cycle. Cell 50: 59–68.
   PubMedGoogle Scholar
• Grasser, F. A., P. G. Murray, E. Kremmer, K. Klein, K. Remberger, W. Feiden, G. Reynolds, G. Niedobitek, L. S. Young, and N. Mueller-Lantzsch. 1994. Monoclonal antibodies directed against the Epstein-Barr virus-encoded nuclear antigen 1 (EBNA1): immunohistologic detection of EBNA1 in the malignant cells of Hodgkin's disease. Blood 84: 3792–3798.
   PubMed Web of Science ®Google Scholar
• Hammerschmidt, W., and B. Sugden. 1988. Identification and characterization of oriLyt, a lytic origin of DNA replication of Epstein-Barr virus. Cell 55: 427–433.
   PubMed Web of Science ®Google Scholar
• Herbig, U., K. Weisshart, P. Taneja, and E. Fanning. 1999. Interaction of the transcription factor TFIID with simian virus 40 (SV40) large T antigen interferes with replication of SV40 DNA in vitro. J. Virol. 73: 1099–1107.
   PubMedGoogle Scholar
• Lambert, P. F., B. C. Monk, and P. M. Howley. 1990. Phenotypic analysis of bovine papillomavirus type 1 E2 repressor mutants. J. Virol. 64: 950–956.
   PubMedGoogle Scholar
• Lambert, P. F., B. A. Spalholz, and P. M. Howley. 1987. A transcriptional repressor encoded by BPV-1 shares a common carboxy-terminal domain with the E2 transactivator. Cell 50: 69–78.
   PubMedGoogle Scholar
• Law, M. F., D. R. Lowy, I. Dvoretzky, and P. M. Howley. 1981. Mouse cells transformed by bovine papillomavirus contain only extrachromosomal viral DNA sequences. Proc. Natl. Acad. Sci. USA 78: 2727–2731.
   PubMed Web of Science ®Google Scholar
• Lee, K.-Y., T. R. Broker, and L. T. Chow. 1998. Transcription factor YY1 represses cell-free replication from human papillomavirus origins. J. Virol. 72: 4911–4917.
   PubMed Web of Science ®Google Scholar
• Leight, E. R., and B. Sugden. 2000. EBNA-1: a protein pivotal to latent infection by Epstein-Barr virus. Rev. Med. Virol. 10: 83–100.
   PubMed Web of Science ®Google Scholar
• Lepik, D., and M. Ustav. 2000. Cell-specific modulation of papovavirus replication by tumor suppressor protein p53. J. Virol. 74: 4688–4697.
   PubMedGoogle Scholar
• Li, R., and M. R. Botchan. 1994. Acidic transcription factors alleviate nucleosome-mediated repression of DNA replication of bovine papillomavirus type 1. Proc. Natl. Acad. Sci. USA 91: 7051–7055.
   PubMedGoogle Scholar
• Lim, D. A., M. Gossen, C. W. Lehman, and M. R. Botchan. 1998. Competition for DNA binding sites between the short and long forms of E2 dimers underlies repression in bovine papillomavirus type 1 DNA replication control. J. Virol. 72: 1931–1940.
   PubMedGoogle Scholar
• McBride, A. A., J. C. Byrne, and P. M. Howley. 1989. E2 polypeptides encoded by bovine papillomavirus type 1 form dimers through the common carboxyl-terminal domain: transactivation is mediated by the conserved amino-terminal domain. Proc. Natl. Acad. Sci. USA 86: 510–514.
   PubMed Web of Science ®Google Scholar
• McBride, A. A., H. Romanczuk, and P. M. Howley. 1991. The papillomavirus E2 regulatory proteins. J. Biol. Chem. 266: 18411–18414.
   PubMed Web of Science ®Google Scholar
• Melendy, T., and R. Li. 2001. Chromatin remodeling and initiation of DNA replication. Front. Biosci. 6: D1048–D1053.
   PubMedGoogle Scholar
• Miller, S. D., G. Farmer, and C. Prives. 1995. p53 inhibits DNA replication in vitro in a DNA-binding-dependent manner. Mol. Cell. Biol. 15: 6554–6560.
   PubMedGoogle Scholar
• Murakami, Y., and Y. Ito. 1999. Transcription factors in DNA replication. Front. Biosci. 4: D824–D833.
   PubMedGoogle Scholar
• Remm, M., R. Brain, and J. R. Jenkins. 1992. The E2 binding sites determine the efficiency of replication for the origin of human papillomavirus type 18. Nucleic Acids Res. 20: 6015–6021.
   PubMedGoogle Scholar
• Rickinson, A. B., and E. Kieff. 2001. Epstein-Barr virus, p. 2575–2627. In D. M. Knipe and P. M. Howley (ed.), Virology, 4th ed., vol. 2. Lippincott Williams & Wilkins, Philadelphia, Pa.
   Google Scholar
• Riese, D. J., II, J. Settleman, K. Neary, and D. DiMaio. 1990. Bovine papillomavirus E2 repressor mutant displays a high-copy-number phenotype and enhanced transforming activity. J. Virol. 64: 944–949.
   PubMedGoogle Scholar
• Russell, J., and M. R. Botchan. 1995. cis-Acting components of human papillomavirus (HPV) DNA replication: linker substitution analysis of the HPV type 11 origin. J. Virol. 69: 651–660.
   PubMedGoogle Scholar
• Schepers, A., M. Ritzi, K. Bousset, E. Kremmer, J. L. Yates, J. Harwood, J. F. Diffley, and W. Hammerschmidt. 2001. Human origin recognition complex binds to the region of the latent origin of DNA replication of Epstein-Barr virus. EMBO J. 20: 4588–4602.
   PubMedGoogle Scholar
• Stenlund, A. 1996. Papillomavirus DNA replication, p. 679–698. In M. DePamphilis (ed.), DNA replication in eukaryotic cells. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
   Google Scholar
• Stubenrauch, F., A. M. E. Colbert, and L. A. Laimins. 1998. Transactivation by the E2 protein of oncogenic human papillomavirus type 31 is not essential for early and late viral functions. J. Virol. 72: 8115–8123.
   PubMedGoogle Scholar
• Stubenrauch, F., M. Hummel, T. Iftner, and L. A. Laimins. 2000. The E8∧E2C protein, a negative regulator of viral transcription and replication, is required for extrachromosomal maintenance of human papillomavirus type 31 in keratinocytes. J. Virol. 74: 1178–1186.
   PubMedGoogle Scholar
• Stubenrauch, F., H. B. Lim, and L. A. Laimins. 1998. Differential requirements for conserved E2 binding sites in the life cycle of oncogenic human papillomavirus type 31. J. Virol. 72: 1071–1077.
   PubMedGoogle Scholar
• Stubenrauch, F., T. Zobel, and T. Iftner. 2001. The E8 domain confers a novel long-distance transcriptional repression activity on the E8∧E2C protein of high-risk human papillomavirus type 31. J. Virol. 75: 4139–4149.
   PubMedGoogle Scholar
• Ustav, M., E. Ustav, P. Szymanski, and A. Stenlund. 1991. Identification of the origin of replication of bovine papillomavirus and characterization of the viral origin recognition factor E1. EMBO J. 10: 4321–4329.
   PubMedGoogle Scholar
• Yang, L., R. Li, I. J. Mohr, R. Clark, and M. R. Botchan. 1991. Activation of BPV-1 replication in vitro by the transcription factor E2. Nature 353: 628–632.
   PubMedGoogle Scholar
• Yates, J., N. Warren, D. Reisman, and B. Sugden. 1984. A cis-acting element from the Epstein-Barr viral genome that permits stable replication of recombinant plasmids in latently infected cells. Proc. Natl. Acad. Sci. USA 81: 3806–3810.
   PubMed Web of Science ®Google Scholar
• Yates, J. L., and N. Guan. 1991. Epstein-Barr virus-derived plasmids replicate only once per cell cycle and are not amplified after entry into cells. J. Virol. 65: 483–488.
   PubMed Web of Science ®Google Scholar
• Yates, J. L., N. Warren, and B. Sugden. 1985. Stable replication of plasmids derived from Epstein-Barr virus in various mammalian cells. Nature 313: 812–815.
   PubMed Web of Science ®Google Scholar
• zur Hausen, H. 1994. Human pathogenic papillomaviruses, p. 131–156. Springer-Verlag KG, Berlin, Germany.
   Google Scholar
• zur Hausen, H. 1996. Papillomavirus infections—a major cause of human cancers. Biochim. Biophys. Acta 1288: F55–F78.
   PubMed Web of Science ®Google Scholar