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DNA Dynamics and Chromosome Structure

Rapid, Stabilizing Palindrome Rearrangements in Somatic Cells by the Center-Break Mechanism

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Pages 8740-8750 | Received 01 Jul 2003, Accepted 28 Aug 2003, Published online: 27 Mar 2023

REFERENCES

  • Akgün, E., J. Zahn, S. Baumes, G. Brown, F. Liang, T. J. Romanienko, S. Lewis, and M. Jasin. 1997. Palindrome resolution and recombination in the mammalian germline. Mol. Cell. Biol. 17: 5559–5570.
  • Benham, C. J., A. G. Savitt, and W. R. Bauer. 2002. Extrusion of an imperfect palindrome to a cruciform in superhelical DNA: complete determination of energetics using a statistical mechanical model. J. Mol. Biol. 316: 563–581.
  • Cho, S. K., T. D. Webber, J. R. Carlyle, T. Nakano, S. M. Lewis, and J. C. Zúñiga-Pflücker. 1999. Functional characterization of B lymphocytes generated in vitro from embryonic stem cells. Proc. Natl. Acad. Sci. USA 96: 9797–9802.
  • Collick, A., J. Drew, J. Penberth, P. Bois, J. Luckett, F. Scaerou, A. Jeffreys, and W. Reik. 1996. Instability of long inverted repeats within mouse transgenes. EMBO J. 15: 1163–1171.
  • Cunningham, L. A. 2002. Characterization of palindrome instability in mammalian cell lines. Masters thesis. University of Toronto, Toronto, Canada.
  • Drost, J. B., and W. R. Lee. 1998. The developmental basis for germline mosaicism in mouse and Drosophila melanogaster. Genetica 103: 421–443.
  • Edelmann, L., E. Spiteri, K. Koren, V. Pulijaal, M. G. Bialer, A. Shanske, R. Goldberg, and B. E. Morrow. 2001. AT-Rich palindromes mediate the constitutional t(11;22) translocation. Am. J. Hum. Genet. 68: 1–13.
  • Gorbunova, V., and A. A. Levy. 1997. Non-homologous DNA end joining in plant cells is associated with deletions and filler DNA insertions. Nucleic Acids Res. 25: 4650–4657.
  • Henthorn, P. A., D. L. Mager, T. H. J. Huisman, and O. Smithies. 1986. A gene deletion ending within a complex array of repeated sequences 3′ to the human b-globin gene cluster. Proc. Natl. Acad. Sci. USA 83: 5194–5198.
  • Honchel, R., B. A. Rosenzweig, K. L. Thompson, K. T. Blanchard, S. M. Furst, R. E. Stoll, and F. D. Sistare. 2001. Loss of palindromic symmetry in Tg. AC mice with a nonresponder phenotype. Mol Carcinog. 30: 99–110.
  • Hudson, C. R., J. G. Frye, F. D. Quinn, and F. C. Gherardini. 2001. Increased expression of Borrelia burgdorferi vlsE in response to human endothelial cell membranes. Mol. Microbiol. 41: 229–239.
  • Hyrien, O., M. Debatisse, G. Buttin, and B. R. de Saint Vincent. 1987. A hotspot for novel amplification joints in a mosaic of Alu-like repeats and palindromic A+T-rich DNA. EMBO J. 6: 2401–2408.
  • Jacks, T., L. Remington, B. O. Williams, E. M. Schmitt, S. Halachmi, R. T. Bronson, and R. A. Weinberg. 1994. Tumor spectrum analysis in p53-mutant mice. Curr. Biol. 4: 1–7.
  • Jin, R., and R. P. Novick. 2001. Role of the double-strand origin cruciform in pT181 replication. Plasmid 46: 95–105.
  • Johnson, R. D., and M. Jasin. 2000. Sister chromatid gene conversion is a prominent double-strand break repair pathway in mammalian cells. EMBO J. 19: 3398–3407.
  • Kim, E. L., H. Peng, F. M. Esparza, S. Z. Maltchenko, and M. K. Stachowiak. 1998. Cruciform-extruding regulatory element controls cell-specific activity of the tyrosine hydroxylase gene promoter. Nucleic Acids Res. 26: 1793–1800.
  • Kurahashi, H., and B. S. Emanuel. 2001. Long AT-rich palindromes and the constitutional t(11;22) breakpoint. Hum. Mol. Genet. 10: 2605–2617.
  • Kurahashi, H., T. Shaikh, M. Takata, T. Toda, and B. S. Emanuel. 2003. The constitutional t(17;22): another translocation mediated by palindromic AT-rich repeats. Am. J. Hum. Genet. 72:733–738.
  • Leach, D. R. F. 1994. Long DNA palindromes, cruciform structures, genetic instability and secondary structure repair. BioEssays 16: 893–900.
  • Lewis, S. M. 1994. P nucleotide insertions and the resolution of hairpin DNA structures in mammalian cells. Proc. Natl. Acad. Sci. USA 91: 1332–1336.
  • Lewis, S. M. 1999. Palindromy is eliminated through a structure-specific recombination process in rodent cells. Nucleic Acids Res. 27: 2521–2528.
  • Lewis, S. M., E. Akgün, and M. Jasin. 1999. Palindromic DNA and genomic stability: further studies. Ann. N. Y. Acad. Sci. 870: 45–57.
  • Lobachev, K. S., D. A. Gordenin, and M. A. Resnick. 2002. The Mre11 complex is required for repair of hairpin-capped double-strand breaks and prevention of chromosome rearrangements. Cell 108: 183–193.
  • Ma, Y., U. Pannicke, K. Schwarz, and M. R. Lieber. 2002. Hairpin opening and overhang processing by an Artemis/DNA-dependent protein kinase complex in nonhomologous end joining and V(D)J recombination. Cell 108: 781–794.
  • Malagon, F., and A. Aguilera. 1998. Genetic stability and DNA rearrangements associated with a 2 x 1.1-Kb perfect palindrome in Escherichia coli. Mol. Gen. Genet. 259: 639–644.
  • Mizuuchi, K., M. Mizuuchi, and M. Gellert. 1982. Cruciform structures in palindromic DNA are favored by DNA supercoiling. J. Mol. Biol. 156: 229–243.
  • Mostecki, J., A. Halgren, A. Radfar, Z. Sachs, J. Ravitz, K. C. Thome, and N. Rosenberg. 2000. Loss of heterozygosity at the Ink4a/Arf locus facilitates Abelson virus transformation of pre-B cells. J. Virol. 74: 9479–9487.
  • Repping, S., H. Skaletsky, J. Lange, S. Silber, F. Van Der Veen, R. D. Oates, D. C. Page, and S. Rozen. 2002. Recombination between palindromes P5 and P1 on the human Y chromosome causes massive deletions and spermatogenic failure. Am. J. Hum. Genet. 71: 906–922.
  • Rosenberg, N. 1994. abl-mediated transformation, immunoglobulin gene rearrangements and arrest of B lymphocyte differentiation. Semin. Cancer Biol. 5: 95–102.
  • Rosenberg, N., and D. Baltimore. 1976. A quantitative assay for transformation of bone marrow cells by Abelson murine leukemia virus. J. Exp. Med. 143: 1453–1463.
  • Rosenberg, N., D. Baltimore, and C. D. Scher. 1975. In vitro transformation of lymphoid cells by Abelson murine leukemia virus. Proc. Natl. Acad. Sci. USA 72: 1932–1936.
  • Tanaka, H., S. J. Tapscott, B. J. Trask, and M. C. Yao. 2002. Short inverted repeats initiate gene amplification through the formation of a large DNA palindrome in mammalian cells. Proc. Natl. Acad. Sci. USA 99: 8772–8777.
  • Tapia-Paez, I., M. Kost-Alimova, P. Hu, B. A. Roe, E. Blennow, L. Fedorova, S. Imreh, and J. P. Dumanski. 2001. The position of t(11;22)(q23;q11) constitutional translocation breakpoint is conserved among its carriers. Hum. Genet. 109: 167–177.
  • Thome, K. C., A. Radfar, and N. Rosenberg. 1997. Mutation of Tp53 contributes to the malignant phenotype of Abelson virus-transformed lymphoid cells. J. Virol. 71: 8149–8156.
  • Unnikrishnan, I., A. Radfar, J. Jenab-Wolcott, and N. Rosenberg. 1999. p53 mediates apoptotic crisis in primary Abelson virus-transformed pre-B cells. Mol. Cell. Biol. 19: 4825–4831.
  • Unnikrishnan, I., and N. Rosenberg. 2003. Absence of p53 complements defects in Abelson murine leukemia virus signaling. J. Virol. 77: 6208–6215.
  • Weckert, H. A., J. A. Hughes, E. M. Benson, and I. S. Dunn. 2000. Quantifiable analysis of human immunoglobulin heavy chain class-switch recombination to all isotypes. J. Immunol. Methods 233: 141–158.
  • Willwand, K., A. Moroianu, R. Horlein, W. Stremmel, and J. Rommelaere. 2002. Specific interaction of the nonstructural protein NS1 of minute virus of mice (MVM) with [ACCA](2) motifs in the centre of the right-end MVM DNA palindrome induces hairpin-primed viral DNA replication. J. Gen. Virol. 83: 1659–1664.
  • Zhou, Z. H., E. Akgun, and M. Jasin. 2001. Repeat expansion by homologous recombination in the mouse germ line at palindromic sequences. Proc. Natl. Acad. Sci. USA 98: 8326–8333.

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