Regulation of E2F1 by BRCT Domain-Containing Protein TopBP1

REFERENCES

• Banin, S., L. Moyal, S. Shieh, Y. Taya, C. W. Anderson, L. Chessa, N. I. Smorodinsky, C. Prives, Y. Reiss, Y. Shiloh, and Y. Ziv. 1998. Enhanced phosphorylation of p53 by ATM in response to DNA damage. Science 281: 1674–1677.
   PubMed Web of Science ®Google Scholar
• Bates, S., A. C. Phillips, P. A. Clark, F. Stott, G. Peters, R. L. Ludwig, and K. H. Vousden. 1998. p14ARF links the tumour suppressors RB and p53. Nature 395: 124–125.
   PubMed Web of Science ®Google Scholar
• Bochar, D. A., L. Wang, H. Beniya, A. Kinev, Y. Xue, W. S. Lane, W. Wang, F. Kashanchi, and R. Shiekhattar. 2000. BRCA1 is associated with a human SWI/SNF-related complex: linking chromatin remodeling to breast cancer. Cell 102: 257–265.
   PubMed Web of Science ®Google Scholar
• Boner, W., E. R. Taylor, E. Tsirimonaki, K. Yamane, M. S. Campo, and I. M. Morgan. 2002. A functional interaction between the human papillomavirus type 16 transcription/replication factor E2 and the DNA damage response protein TopBP1. J. Biol. Chem. 4: 4.
   Google Scholar
• Bork, P., K. Hofmann, P. Bucher, A. F. Neuwald, S. F. Altschul, and E. V. Koonin. 1997. A superfamily of conserved domains in DNA damage-responsive cell cycle checkpoint proteins. FASEB J. 11: 68–76.
   PubMed Web of Science ®Google Scholar
• Bosco, G., W. Du, and T. L. Orr-Weaver. 2001. DNA replication control through interaction of E2F-RB and the origin recognition complex. Nat. Cell Biol. 3: 289–295.
   PubMed Web of Science ®Google Scholar
• Callebaut, I., and J. P. Mornon. 1997. From BRCA1 to RAP1: a widespread BRCT module closely associated with DNA repair. FEBS Lett. 400: 25–30.
   PubMed Web of Science ®Google Scholar
• DeGregori, J., G. Leone, A. Miron, L. Jakoi, and J. R. Nevins. 1997. Distinct roles for E2F proteins in cell growth control and apoptosis. Proc. Natl. Acad. Sci. USA 94: 7245–7250.
   PubMed Web of Science ®Google Scholar
• Dyson, N. 1998. The regulation of E2F by pRB-family proteins. Genes Dev. 12: 2245–2262.
   PubMed Web of Science ®Google Scholar
• Field, S. J., F. Y. Tsai, F. Kuo, A. M. Zubiaga, W. G. Kaelin, Jr., D. M. Livingston, S. H. Orkin, and M. E. Greenberg. 1996. E2F-1 functions in mice to promote apoptosis and suppress proliferation. Cell 85: 549–561.
   PubMed Web of Science ®Google Scholar
• He, T. C., S. Zhou, L. T. da Costa, J. Yu, K. W. Kinzler, and B. Vogelstein. 1998. A simplified system for generating recombinant adenoviruses. Proc. Natl. Acad. Sci. USA 95: 2509–2514.
   PubMed Web of Science ®Google Scholar
• Herold, S., M. Wanzel, V. Beuger, C. Frohme, D. Beul, T. Hillukkala, J. Syvaoja, H. P. Saluz, F. Haenel, and M. Eilers. 2002. Negative regulation of the mammalian UV response by Myc through association with Miz-1. Mol. Cell 10: 509–521.
   PubMed Web of Science ®Google Scholar
• Honda, Y., M. Tojo, K. Matsuzaki, T. Anan, M. Matsumoto, M. Ando, H. Saya, and M. Nakao. 2002. Cooperation of HECT-domain ubiquitin ligase hHYD and DNA topoisomerase II-binding protein for DNA damage response. J. Biol. Chem. 277: 3599–3605.
   PubMed Web of Science ®Google Scholar
• Kowalik, T. F., J. DeGregori, G. Leone, L. Jakoi, and J. R. Nevins. 1998. E2F1-specific induction of apoptosis and p53 accumulation, which is blocked by Mdm2. Cell Growth Differ. 9: 113–118.
   PubMedGoogle Scholar
• Leone, G., J. DeGregori, Z. Yan, L. Jakoi, S. Ishida, R. S. Williams, and J. R. Nevins. 1998. E2F3 activity is regulated during the cell cycle and is required for the induction of S phase. Genes Dev. 12: 2120–2130.
   PubMed Web of Science ®Google Scholar
• Li, S., P. L. Chen, T. Subramanian, G. Chinnadurai, G. Tomlinson, C. K. Osborne, Z. D. Sharp, and W. H. Lee. 1999. Binding of CtIP to the BRCT repeats of BRCA1 involved in the transcription regulation of p21 is disrupted upon DNA damage. J. Biol. Chem. 274: 11334–11338.
   PubMed Web of Science ®Google Scholar
• Lin, W. C., F. T. Lin, and J. R. Nevins. 2001. Selective induction of E2F1 in response to DNA damage, mediated by ATM-dependent phosphorylation. Genes Dev. 15: 1833–1844.
   PubMed Web of Science ®Google Scholar
• Makiniemi, M., T. Hillukkala, J. Tuusa, K. Reini, M. Vaara, D. Huang, H. Pospiech, I. Majuri, T. Westerling, T. P. Makela, and J. E. Syvaoja. 2001. BRCT domain-containing protein TopBP1 functions in DNA replication and damage response. J. Biol. Chem. 276: 30399–30406.
   PubMed Web of Science ®Google Scholar
• Maser, R. S., O. K. Mirzoeva, J. Wells, H. Olivares, B. R. Williams, R. A. Zinkel, P. J. Farnham, and J. H. Petrini. 2001. Mre11 complex and DNA replication: linkage to E2F and sites of DNA synthesis. Mol. Cell. Biol. 21: 6006–6016.
   PubMed Web of Science ®Google Scholar
• Mirzoeva, O. K., and J. H. Petrini. 2001. DNA damage-dependent nuclear dynamics of the Mre11 complex. Mol. Cell. Biol. 21: 281–288.
   PubMed Web of Science ®Google Scholar
• Moroni, M. C., E. S. Hickman, E. L. Denchi, G. Caprara, E. Colli, F. Cecconi, H. Muller, and K. Helin. 2001. Apaf-1 is a transcriptional target for E2F and p53. Nat. Cell Biol. 3: 552–558.
   PubMed Web of Science ®Google Scholar
• Nelms, B. E., R. S. Maser, J. F. MacKay, M. G. Lagally, and J. H. Petrini. 1998. In situ visualization of DNA double-strand break repair in human fibroblasts. Science 280: 590–592.
   PubMed Web of Science ®Google Scholar
• Nevins, J. R. 1998. Toward an understanding of the functional complexity of the E2F and retinoblastoma families. Cell Growth Differ. 9: 585–593.
   PubMedGoogle Scholar
• Nishikawa, N. S., M. Izumi, H. Uchida, M. Yokoi, H. Miyazawa, and F. Hanaoka. 2000. Cloning and characterization of the 5′-upstream sequence governing the cell cycle-dependent transcription of mouse DNA polymerase alpha 68 kDa subunit gene. Nucleic Acids Res. 28: 1525–1534.
   PubMedGoogle Scholar
• Orr, W., K. Komitopoulou, and F. C. Kafatos. 1984. Mutants suppressing in trans chorion gene amplification in Drosophila. Proc. Natl. Acad. Sci. USA 81: 3773–3777.
   PubMedGoogle Scholar
• Ren, B., H. Cam, Y. Takahashi, T. Volkert, J. Terragni, R. A. Young, and B. D. Dynlacht. 2002. E2F integrates cell cycle progression with DNA repair, replication, and G2/M checkpoints. Genes Dev. 16: 245–256.
   PubMed Web of Science ®Google Scholar
• Royzman, I., R. J. Austin, G. Bosco, S. P. Bell, and T. L. Orr-Weaver. 1999. ORC localization in Drosophila follicle cells and the effects of mutations in dE2F and dDP. Genes Dev. 13: 827–840.
   PubMed Web of Science ®Google Scholar
• Vigo, E., H. Muller, E. Prosperini, G. Hateboer, P. Cartwright, M. C. Moroni, and K. Helin. 1999. CDC25A phosphatase is a target of E2F and is required for efficient E2F-induced S phase. Mol. Cell. Biol. 19: 6379–6395.
   PubMed Web of Science ®Google Scholar
• Wang, H., N. Shao, Q. M. Ding, J. Cui, E. S. Reddy, and V. N. Rao. 1997. BRCA1 proteins are transported to the nucleus in the absence of serum and splice variants BRCA1a, BRCA1b are tyrosine phosphoproteins that associate with E2F, cyclins and cyclin dependent kinases. Oncogene 15: 143–157.
   PubMed Web of Science ®Google Scholar
• Wang, Y., D. Cortez, P. Yazdi, N. Neff, S. J. Elledge, and J. Qin. 2000. BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures. Genes Dev. 14: 927–939.
   PubMed Web of Science ®Google Scholar
• Wu, L., C. Timmers, B. Maiti, H. I. Saavedra, L. Sang, G. T. Chong, F. Nuckolls, P. Giangrande, F. A. Wright, S. J. Field, M. E. Greenberg, S. Orkin, J. R. Nevins, M. L. Robinson, and G. Leone. 2001. The E2F1-3 transcription factors are essential for cellular proliferation. Nature 414: 457–462.
   PubMed Web of Science ®Google Scholar
• Wu, L. C., Z. W. Wang, J. T. Tsan, M. A. Spillman, A. Phung, X. L. Xu, M. C. Yang, L. Y. Hwang, A. M. Bowcock, and R. Baer. 1996. Identification of a RING protein that can interact in vivo with the BRCA1 gene product. Nat. Genet. 14: 430–440.
   PubMed Web of Science ®Google Scholar
• Yamamoto, R. R., J. M. Axton, Y. Yamamoto, R. D. Saunders, D. M. Glover, and D. S. Henderson. 2000. The Drosophila mus101 gene, which links DNA repair, replication and condensation of heterochromatin in mitosis, encodes a protein with seven BRCA1 C-terminus domains. Genetics 156: 711–721.
   PubMedGoogle Scholar
• Yamane, K., M. Kawabata, and T. Tsuruo. 1997. A DNA-topoisomerase-II-binding protein with eight repeating regions similar to DNA-repair enzymes and to a cell-cycle regulator. Eur. J. Biochem. 250: 794–799.
   PubMedGoogle Scholar
• Yamane, K., and T. Tsuruo. 1999. Conserved BRCT regions of TopBP1 and of the tumor suppressor BRCA1 bind strand breaks and termini of DNA. Oncogene 18: 5194–5203.
   PubMedGoogle Scholar
• Yamane, K., X. Wu, and J. Chen. 2002. A DNA damage-regulated BRCT-containing protein, TopBP1, is required for cell survival. Mol. Cell. Biol. 22: 555–566.
   PubMed Web of Science ®Google Scholar
• Yamasaki, L., T. Jacks, R. Bronson, E. Goillot, E. Harlow, and N. J. Dyson. 1996. Tumor induction and tissue atrophy in mice lacking E2F-1. Cell 85: 537–548.
   PubMed Web of Science ®Google Scholar
• Yarden, R. I., and L. C. Brody. 1999. BRCA1 interacts with components of the histone deacetylase complex. Proc. Natl. Acad. Sci. USA 96: 4983–4988.
   PubMed Web of Science ®Google Scholar
• Zhou, B. B., and S. J. Elledge. 2000. The DNA damage response: putting checkpoints in perspective. Nature 408: 433–439.
   PubMed Web of Science ®Google Scholar