Parent-of-Origin-Specific Binding of Nuclear Hormone Receptor Complexes in the H19-Igf2 Imprinting Control Region

REFERENCES

• Arnold, R., Burcin M., Kaiser B., Muller M., and Renkawitz R.. 1996. DNA bending by the silencer protein NeP1 is modulated by TR and RXR. Nucleic Acids Res. 24:2640–2647.
   PubMedGoogle Scholar
• Bartolomei, M. S., Webber A. L., Brunkow M. E., and Tilghman S. M.. 1993. Epigenetic mechanisms underlying the imprinting of the mouse H19 gene. Genes Dev. 7:1663–1673.
   PubMed Web of Science ®Google Scholar
• Bell, A. C., and Felsenfeld G.. 2000. Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 gene. Nature 405:482–485.
   PubMed Web of Science ®Google Scholar
• Bell, A. C., West A. G., and Felsenfeld G.. 1999. The protein CTCF is required for the enhancer blocking activity of vertebrate insulators. Cell 98:387–396.
   PubMed Web of Science ®Google Scholar
• Collingwood, T. N., Urnov F. D., and Wolffe A. P.. 1999. Nuclear receptors: coactivators, corepressors and chromatin remodeling in the control of transcription. J. Mol. Endocrinol. 23:255–275.
   PubMed Web of Science ®Google Scholar
• Davis, T. L., Trasler J. M., Moss S. B., Yang G. J., and Bartolomei M. S.. 1999. Acquisition of the H19 methylation imprint occurs differentially on the parental alleles during spermatogenesis. Genomics 58:18–28.
   PubMed Web of Science ®Google Scholar
• Di Croce, L., Raker V. A., Corsaro M., Fazi F., Fanelli M., Faretta M., Fuks F., Lo Coco F., Kouzarides T., Nervi C., Minucci S., and Pelicci P. G.. 2002. Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor. Science 295:1079–1082.
   PubMed Web of Science ®Google Scholar
• Hark, A. T., Schoenherr C. J., Katz D. J., Ingram R. S., Levorse J. M., and Tilghman S. M.. 2000. CTCF mediates methylation-sensitive enhancer-blocking activity at the H19/Igf2 locus. Nature 405:486–489.
   PubMed Web of Science ®Google Scholar
• Hogan, B., Beddington R., Constantini F., and Lacy E.. 1994. Manipulating the mouse embryo: a laboratory manual. Cold Spring Harbor Laboratory Press, New York, N.Y.
   Google Scholar
• Kaffer, C. R., Srivastava M., Park K. Y., Ives E., Hsieh S., Batlle J., Grinberg A., Huang S. P., and Pfeifer K.. 2000. A transcriptional insulator at the imprinted H19/Igf2 locus. Genes Dev. 14:1908–1919.
   PubMed Web of Science ®Google Scholar
• Kanduri, C., Pant V., Loukinov D., Pugacheva E., Qi C. F., Wolffe A., Ohlsson R., and Lobanenkov V. V.. 2000. Functional association of CTCF with the insulator upstream of the H19 gene is parent of origin-specific and methylation-sensitive. Curr. Biol. 10:853–856.
   PubMed Web of Science ®Google Scholar
• Kato, S., Sasaki H., Suzawa M., Masushige S., Tora L., Chambon P., and Gronemeyer H.. 1995. Widely spaced, directly repeated PuGGTCA elements act as promiscuous enhancers for different classes of nuclear receptors. Mol. Cell. Biol. 15:5858–5867.
   PubMedGoogle Scholar
• Kato, S., Tora L., Yamauchi J., Masushige S., Bellard M., and Chambon P.. 1992. A far upstream estrogen response element of the ovalbumin gene contains several half-palindromic 5′-TGACC-3′ motifs acting synergistically. Cell 68:731–742.
   PubMed Web of Science ®Google Scholar
• Leighton, P. A., Ingram R. S., Eggenschwiler J., Efstratiadis A., and Tilghman S. M.. 1995. Disruption of imprinting caused by deletion of the H19 gene region in mice. Nature 375:34–39.
   PubMed Web of Science ®Google Scholar
• Leighton, P. A., Saam J. R., Ingram R. S., Stewart C. L., and Tilghman S. M.. 1995. An enhancer deletion affects both H19 and Igf2 expression. Genes Dev. 9:2079–2089.
   PubMed Web of Science ®Google Scholar
• Li, E., Beard C., and Jaenisch R.. 1993. Role for DNA methylation in genomic imprinting. Nature 366:362–365.
   PubMed Web of Science ®Google Scholar
• Li, J., Lin Q., Yoon H. G., Huang Z. Q., Strahl B. D., Allis C. D., and Wong J.. 2002. Involvement of histone methylation and phosphorylation in regulation of transcription by thyroid hormone receptor. Mol. Cell. Biol. 22:5688–5697.
   PubMedGoogle Scholar
• Lutz, M., Burke L. J., LeFevre P., Myers F. A., Thorne A. W., Crane-Robinson C., Bonifer C., Filippova G. N., Lobanenkov V., and Renkawitz R.. 2003. Thyroid hormone-regulated enhancer blocking: cooperation of CTCF and thyroid hormone receptor. EMBO J. 22:1579–1587.
   PubMedGoogle Scholar
• Malkov, M., Fisher Y., and Don J.. 1998. Developmental schedule of the postnatal rat testis determined by flow cytometry. Biol. Reprod. 59:84–92.
   PubMedGoogle Scholar
• Mann, J. R., Szabó P. E., Reed M. R., and Singer-Sam J.. 2000. Methylated DNA sequences in genomic imprinting. Crit. Rev. Eukaryot. Gene Expr. 10:241–257.
   PubMed Web of Science ®Google Scholar
• Maxam, A. M., and Gilbert W.. 1977. A new method for sequencing DNA. Proc. Natl. Acad. Sci. USA 74:560–564.
   PubMed Web of Science ®Google Scholar
• McLaughlin, K. J., Szabó P., Haegel H., and Mann J. R.. 1996. Mouse embryos with paternal duplication of an imprinted chromosome 7 region die at midgestation and lack placental spongiotrophoblast. Development 122:265–270.
   PubMed Web of Science ®Google Scholar
• Nabetani, A., Hatada I., Morisaki H., Oshimura M., and Mukai T.. 1997. Mouse U2af1-rs1 is a neomorphic imprinted gene. Mol. Cell. Biol. 17:789–798.
   PubMedGoogle Scholar
• Pant, V., Mariano P., Kanduri C., Mattsson A., Lobanenkov V., Heuchel R., and Ohlsson R.. 2003. The nucleotides responsible for the direct physical contact between the chromatin insulator protein CTCF and the H19 imprinting control region manifest parent of origin-specific long-distance insulation and methylation-free domains. Genes Dev. 17:586–590.
   PubMed Web of Science ®Google Scholar
• Pfeifer, G. P., and Riggs A. D.. 1991. Chromatin differences between active and inactive X chromosomes revealed by genomic footprinting of permeabilized cells using DNase I and ligation-mediated PCR. Genes Dev. 5:1102–1113.
   PubMedGoogle Scholar
• Ripoche, M. A., Kress C., Poirier F., and Dandolo L.. 1997. Deletion of the H19 transcription unit reveals the existence of a putative imprinting control element. Genes Dev. 11:1596–1604.
   PubMed Web of Science ®Google Scholar
• Schoenherr, C. J., Levorse J. M., and Tilghman S. M.. 2003. CTCF maintains differential methylation at the Igf2/H19 locus. Nat. Genet. 33:66–69.
   PubMed Web of Science ®Google Scholar
• Searle, A. G., and Beechey C. V.. 1990. Genome imprinting phenomena on mouse chromosome 7. Genet. Res. 56:237–244.
   PubMedGoogle Scholar
• Shibata, H., Ueda T., Kamiya M., Yoshiki A., Kusakabe M., Plass C., Held W. A., Sunahara S., Katsuki M., Muramatsu M., and Hayashizaki Y.. 1997. An oocyte-specific methylation imprint center in the mouse U2afbp-rs/U2af1-rs1 gene marks the establishment of allele-specific methylation during preimplantation development. Genomics 44:171–178.
   PubMed Web of Science ®Google Scholar
• Shibata, H., Yoda Y., Kato R., Ueda T., Kamiya M., Hiraiwa N., Yoshiki A., Plass C., Pearsall R. S., Held W. A., Muramatsu M., Sasaki H., Kusakabe M., and Hayashizaki Y.. 1998. A methylation imprint mark in the mouse imprinted gene Grf1/Cdc25Mm locus shares a common feature with the U2afbp-rs gene: an association with a short tandem repeat and a hypermethylated region. Genomics 49:30–37.
   PubMedGoogle Scholar
• Song, M. R., Lee S. K., Seo Y. W., Choi H. S., Lee J. W., and Lee M. O.. 1998. Differential modulation of transcriptional activity of oestrogen receptors by direct protein-protein interactions with retinoid receptors. Biochem. J. 336(Pt. 3):711–717.
   PubMedGoogle Scholar
• Srivastava, M., Hsieh S., Grinberg A., Williams-Simons L., Huang S. P., and Pfeifer K.. 2000. H19 and Igf2 monoallelic expression is regulated in two distinct ways by a shared cis acting regulatory region upstream of H19. Genes Dev. 14:1186–1195.
   PubMedGoogle Scholar
• Sucov, H. M., Dyson E., Gumeringer C. L., Price J., Chien K. R., and Evans R. M.. 1994. RXR alpha mutant mice establish a genetic basis for vitamin A signaling in heart morphogenesis. Genes Dev. 8:1007–1018.
   PubMed Web of Science ®Google Scholar
• Szabó, P., Tang S. H., Rentsendorj A., Pfeifer G. P., and Mann J. R.. 2000. Maternal-specific footprints at putative CTCF sites in the H19 imprinting control region give evidence for insulator function. Curr. Biol. 10:607–610.
   PubMed Web of Science ®Google Scholar
• Szabó, P. E., Hubner K., Scholer H., and Mann J. R.. 2002. Allele-specific expression of imprinted genes in mouse migratory primordial germ cells. Mech. Dev. 115:157–160.
   PubMed Web of Science ®Google Scholar
• Szabó, P. E., and Mann J. R.. 1995. Biallelic expression of imprinted genes in the mouse germ line: implications for erasure, establishment, and mechanisms of genomic imprinting. Genes Dev. 9:1857–1868.
   PubMed Web of Science ®Google Scholar
• Szabó, P. E., Pfeifer G. P., and Mann J. R.. 1998. Characterization of novel parent-specific epigenetic modifications upstream of the imprinted mouse H19 gene. Mol. Cell. Biol. 18:6767–6776.
   PubMedGoogle Scholar
• Szabó, P. E., Pfeifer G. P., Miao F., O'Connor T. R., and Mann J. R.. 2000. Improved in vivo dimethyl sulfate footprinting using AlkA protein: DNA-protein interactions at the mouse H19 gene promoter in primary embryo fibroblasts. Anal. Biochem. 283:112–116.
   PubMedGoogle Scholar
• Szabó, P. E., Tang S. H., Reed M. R., Silva F. J., Tsark W. M., and Mann J. R.. 2002. The chicken beta-globin insulator element conveys chromatin boundary activity but not imprinting at the mouse Igf2/H19 domain. Development 129:897–904.
   PubMed Web of Science ®Google Scholar
• Szabó, P. E., Tang S.-H. E., Silva F. J., Tsark W. M. K., and Mann J. R.. 2004. Role of CTCF binding sites in the Igf2/H19 imprinting control region. Mol. Cell. Biol. 24:4791–4800.
   PubMed Web of Science ®Google Scholar
• Tang, S. H., Silva F. J., Tsark W. M., and Mann J. R.. 2002. A Cre/loxP-deleter transgenic line in mouse strain 129S1/SvImJ. Genesis 32:199–202.
   PubMedGoogle Scholar
• Thorvaldsen, J. L., Duran K. L., and Bartolomei M. S.. 1998. Deletion of the H19 differentially methylated domain results in loss of imprinted expression of H19 and Igf2. Genes Dev. 12:3693–3702.
   PubMed Web of Science ®Google Scholar
• Tornaletti, S., and Pfeifer G. P.. 1995. UV light as a footprinting agent: modulation of UV-induced DNA damage by transcription factors bound at the promoters of three human genes. J. Mol. Biol. 249:714–728.
   PubMedGoogle Scholar
• Tremblay, K. D., Duran K. L., and Bartolomei M. S.. 1997. A 5′ 2-kilobase-pair region of the imprinted mouse H19 gene exhibits exclusive paternal methylation throughout development. Mol. Cell. Biol. 17:4322–4329.
   PubMed Web of Science ®Google Scholar
• Ueda, T., Abe K., Miura A., Yuzuriha M., Zubair M., Noguchi M., Niwa K., Kawase Y., Kono T., Matsuda Y., Fujimoto H., Shibata H., Hayashizaki Y., and Sasaki H.. 2000. The paternal methylation imprint of the mouse H19 locus is acquired in the gonocyte stage during foetal testis development. Genes Cells 5:649–659.
   PubMed Web of Science ®Google Scholar
• Webb, P., Valentine C., Nguyen P., Price R. H., Jr., Marimuthu A., West B. L., Baxter J. D., and Kushner P. J.. 2003. ERbeta binds N-CoR in the presence of estrogens via an LXXLL-like motif in the N-CoR C-terminus. Nucl. Recept. 1:4.
   PubMedGoogle Scholar
• Wyszomierski, S. L., Yeh J., and Rosen J. M.. 1999. Glucocorticoid receptor/signal transducer and activator of transcription 5 (STAT5) interactions enhance STAT5 activation by prolonging STAT5 DNA binding and tyrosine phosphorylation. Mol. Endocrinol. 13:330–343.
   PubMedGoogle Scholar
• Xu, L., Glass C. K., and Rosenfeld M. G.. 1999. Coactivator and corepressor complexes in nuclear receptor function. Curr. Opin. Genet. Dev. 9:140–147.
   PubMed Web of Science ®Google Scholar
• Zemel, S., Bartolomei M. S., and Tilghman S. M.. 1992. Physical linkage of two mammalian imprinted genes, H19 and insulin-like growth factor 2. Nat. Genet. 2:61–65.
   PubMedGoogle Scholar