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Transcriptional Regulation

Synergistic Transcription Activation by Maf and Sox and Their Subnuclear Localization Are Disrupted by a Mutation in Maf That Causes Cataract

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Pages 5694-5709 | Received 12 Oct 2003, Accepted 19 Apr 2004, Published online: 27 Mar 2023

REFERENCES

  • Ambrosetti, D. C., Scholer H. R., Dailey L., and Basilico C.. 2000. Modulation of the activity of multiple transcriptional activation domains by the DNA binding domains mediates the synergistic action of Sox2 and Oct-3 on the fibroblast growth factor-4 enhancer. J. Biol. Chem. 275:23387–23397.
  • Borden, K. L. 2002. Pondering the promyelocytic leukemia protein (PML) puzzle: possible functions for PML nuclear bodies. Mol. Cell. Biol. 22:5259–5269.
  • Boyle, D. L., Takemoto L., Brady J. P., and Wawrousek E. F.. 2003. Morphological characterization of the AlphaA- and AlphaB-crystallin double knockout mouse lens. BMC Ophthalmol. 3:3.
  • Brady, J. P., Garland D., Duglas-Tabor Y., Robison W. G., Jr., Groome A., and Wawrousek E. F.. 1997. Targeted disruption of the mouse alpha A-crystallin gene induces cataract and cytoplasmic inclusion bodies containing the small heat shock protein alpha B-crystallin. Proc. Natl. Acad. Sci. USA 94:884–889.
  • Chen, Q., Dowhan D. H., Liang D., Moore D. D., and Overbeek P. A.. 2002. CREB-binding protein/p300 co-activation of crystallin gene expression. J. Biol. Chem. 277:24081–24089.
  • Chinenov, Y., and Kerppola T. K.. 2001. Close encounters of many kinds: Fos-Jun interactions that mediate transcription regulatory specificity. Oncogene 20:2438–2452.
  • De Angelis, D. A., Miesenbock G., Zemelman B. V., and Rothman J. E.. 1998. PRIM: proximity imaging of green fluorescent protein-tagged polypeptides. Proc. Natl. Acad. Sci. USA 95:12312–12316.
  • Dlakic, M., Grinberg A. V., Leonard D. A., and Kerppola T. K.. 2001. DNA sequence-dependent folding determines the divergence in binding specificities between Maf and other bZIP proteins. EMBO J. 20:828–840.
  • Duncan, M. K., Cvekl A., Li X., and Piatigorsky J.. 2000. Truncated forms of Pax-6 disrupt lens morphology in transgenic mice. Investig. Ophthalmol. Vis. Sci. 41:464–473.
  • Dyck, J. A., Maul G. G., Miller W. H., Jr., Chen J. D., Kakizuka A., and Evans R. M.. 1994. A novel macromolecular structure is a target of the promyelocyte-retinoic acid receptor oncoprotein. Cell 76:333–343.
  • Frey, M. R., and Matera A. G.. 1995. Coiled bodies contain U7 small nuclear RNA and associate with specific DNA sequences in interphase human cells. Proc. Natl. Acad. Sci. USA 92:5915–5919.
  • Fu, X. D., and Maniatis T.. 1990. Factor required for mammalian spliceosome assembly is localized to discrete regions in the nucleus. Nature 343:437–441.
  • Goring, D. R., Bryce D. M., Tsui L. C., Breitman M. L., and Liu Q.. 1993. Developmental regulation and cell type-specific expression of the murine gamma F-crystallin gene is mediated through a lens-specific element containing the gamma F-1 binding site. Dev. Dyn. 196:143–152.
  • Graw, J. 1997. The crystallins: genes, proteins and diseases. Biol. Chem. 378:1331–1348.
  • Grinberg, A. V., and Kerppola T.. 2003. Both Max and TFE3 cooperate with Smad proteins to bind the plasminogen activator inhibitor-1 promoter, but they have opposite effects on transcriptional activity. J. Biol. Chem. 278:11227–11236.
  • Hu, C. D., Chinenov Y., and Kerppola T. K.. 2002. Visualization of interactions among bZIP and Rel family proteins in living cells using bimolecular fluorescence complementation. Mol. Cell 9:789–798.
  • Jamieson, R. V., Munier F., Balmer A., Farrar N., Perveen R., and Black G. C.. 2003. Pulverulent cataract with variably associated microcornea and iris coloboma in a MAF mutation family. Br. J. Ophthalmol. 87:411–412.
  • Jamieson, R. V., Perveen R., Kerr B., Carette M., Yardley J., Heon E., Wirth M. G., van Heyningen V., Donnai D., Munier F., and Black G. C.. 2002. Domain disruption and mutation of the bZIP transcription factor, MAF, associated with cataract, ocular anterior segment dysgenesis and coloboma. Hum. Mol. Genet. 11:33–42.
  • Kamachi, Y., Sockanathan S., Liu Q., Breitman M., Lovell-Badge R., and Kondoh H.. 1995. Involvement of SOX proteins in lens-specific activation of crystallin genes. EMBO J. 14:3510–3519.
  • Kamachi, Y., Uchikawa M., Collignon J., Lovell-Badge R., and Kondoh H.. 1998. Involvement of Sox1, 2 and 3 in the early and subsequent molecular events of lens induction. Development 125:2521–2532.
  • Kamachi, Y., Uchikawa M., and Kondoh H.. 2000. Pairing SOX off: with partners in the regulation of embryonic development. Trends Genet. 16:182–187.
  • Kamachi, Y., Uchikawa M., Tanouchi A., Sekido R., and Kondoh H.. 2001. Pax6 and SOX2 form a co-DNA-binding partner complex that regulates initiation of lens development. Genes Dev. 15:1272–1286.
  • Kataoka, K., Noda M., and Nishizawa M.. 1994. Maf nuclear oncoprotein recognizes sequences related to an AP-1 site and forms heterodimers with both Fos and Jun. Mol. Cell. Biol. 14:700–712.
  • Kawauchi, S., Takahashi S., Nakajima O., Ogino H., Morita M., Nishizawa M., Yasuda K., and Yamamoto M.. 1999. Regulation of lens fiber cell differentiation by transcription factor c-Maf. J. Biol. Chem. 274:19254–19260.
  • Kerppola, T. K., and Curran T.. 1994. A conserved region adjacent to the basic domain is required for recognition of an extended DNA binding site by Maf/Nrl family proteins. Oncogene 9:3149–3158.
  • Kerppola, T. K., and Curran T.. 1994. Maf and Nrl can bind to AP-1 sites and form heterodimers with Fos and Jun. Oncogene 9:675–684.
  • Kim, J. I., Li T., Ho I. C., Grusby M. J., and Glimcher L. H.. 1999. Requirement for the c-Maf transcription factor in crystallin gene regulation and lens development. Proc. Natl. Acad. Sci. USA 96:3781–3785.
  • Kondoh, H. 1999. Transcription factors for lens development assessed in vivo. Curr. Opin. Genet. Dev. 9:301–308.
  • Kusunoki, H., Motohashi H., Katsuoka F., Morohashi A., Yamamoto M., and Tanaka T.. 2003. Solution structure of the DNA-binding domain of MafG. Nat. Struct. Biol. 9:252–256.
  • Liu, J., Hebert M. D., Ye Y., Templeton D. J., Kung H., and Matera A. G.. 2000. Cell cycle-dependent localization of the CDK2-cyclin E complex in Cajal (coiled) bodies. J. Cell Sci. 113:1543–1552.
  • Liu, Q., and Dreyfuss G.. 1996. A novel nuclear structure containing the survival of motor neurons protein. EMBO J. 15:3555–3565.
  • Liu, Q. R., Tini M., Tsui L. C., and Breitman M. L.. 1991. Interaction of a lens cell transcription factor with the proximal domain of the mouse gamma F-crystallin promoter. Mol. Cell. Biol. 11:1531–1537.
  • Lok, S., Breitman M. L., Chepelinsky A. B., Piatigorsky J., Gold R. J., and Tsui L. C.. 1985. Lens-specific promoter activity of a mouse gamma-crystallin gene. Mol. Cell. Biol. 5:2221–2230.
  • Matera, A. G. 1999. Nuclear bodies: multifaceted subdomains of the interchromatin space. Trends Cell Biol. 9:302–309.
  • Muta, M., Kamachi Y., Yoshimoto A., Higashi Y., and Kondoh H.. 2002. Distinct roles of SOX2, Pax6 and Maf transcription factors in the regulation of lens-specific delta1-crystallin enhancer. Genes Cells 7:791–805.
  • Nishiguchi, S., Wood H., Kondoh H., Lovell-Badge R., and Episkopou V.. 1998. Sox1 directly regulates the gamma-crystallin genes and is essential for lens development in mice. Genes Dev. 12:776–781.
  • Nishimoto, M., Fukushima A., Okuda A., and Muramatsu M.. 1999. The gene for the embryonic stem cell coactivator UTF1 carries a regulatory element which selectively interacts with a complex composed of Oct-3/4 and Sox-2. Mol. Cell. Biol. 19:5453–5465.
  • Ogino, H., and Yasuda K.. 2000. Sequential activation of transcription factors in lens induction. Dev. Growth Differ. 42:437–448.
  • Pevny, L. H., and Lovell-Badge R.. 1997. Sox genes find their feet. Curr. Opin. Genet. Dev. 7:338–344.
  • Ramirez-Carrozzi, V., and Kerppola T.. 2003. Asymmetric recognition of nonconsensus AP-1 sites by Fos-Jun and Jun-Jun influences transcriptional cooperativity with NFAT1. Mol. Cell. Biol. 23:1737–1749.
  • Reza, H. M., Ogino H., and Yasuda K.. 2002. L-Maf, a downstream target of Pax6, is essential for chick lens development. Mech. Dev. 116:61–73.
  • Ring, B. Z., Cordes S. P., Overbeek P. A., and Barsh G. S.. 2000. Regulation of mouse lens fiber cell development and differentiation by the Maf gene. Development 127:307–317.
  • Rossi, F., Charlton C. A., and Blau H. M.. 1997. Monitoring protein-protein interactions in intact eukaryotic cells by beta-galactosidase complementation. Proc. Natl. Acad. Sci. USA 94:8405–8410.
  • Rupert, P. B., Daughdrill G. W., Bowerman B., and Matthews B. W.. 1998. A new DNA-binding motif in the Skn-1 binding domain-DNA complex. Nat. Struct. Biol. 5:484–491.
  • Schul, W., Groenhout B., Koberna K., Takagaki Y., Jenny A., Manders E. M., Raska I., van Driel R., and de Jong L.. 1996. The RNA 3′ cleavage factors CstF 64 kDa and CPSF 100 kDa are concentrated in nuclear domains closely associated with coiled bodies and newly synthesized RNA. EMBO J. 15:2883–2892.
  • Schul, W., van Der Kraan I., Matera A. G., van Driel R., and de Jong L.. 1999. Nuclear domains enriched in RNA 3′-processing factors associate with coiled bodies and histone genes in a cell cycle-dependent manner. Mol. Biol. Cell 10:3815–3824.
  • Shimada, N., Aya-Murata T., Reza H. M., and Yasuda K.. 2003. Cooperative action between L-Maf and Sox2 on delta-crystallin gene expression during chick lens development. Mech. Dev. 120:455–465.
  • Tanaka, T., Tsujimura T., Takeda K., Sugihara A., Maekawa A., Terada N., Yoshida N., and Akira S.. 1998. Targeted disruption of ATF4 discloses its essential role in the formation of eye lens fibres. Genes Cells 3:801–810.
  • Wigle, J. T., Chowdhury K., Gruss P., and Oliver G.. 1999. Prox1 function is crucial for mouse lens-fibre elongation. Nat. Genet. 21:318–322.
  • Wistow, G. J., and Piatigorsky J.. 1988. Lens crystallins: the evolution and expression of proteins for a highly specialized tissue. Annu. Rev. Biochem. 57:479–504.
  • Yuan, H., Corbi N., Basilico C., and Dailey L.. 1995. Developmental-specific activity of the FGF-4 enhancer requires the synergistic action of Sox2 and Oct-3. Genes Dev. 9:2635–2645.
  • Zygar, C. A., Cook T. L., and Grainger R. M., Jr. 1998. Gene activation during early stages of lens induction in Xenopus. Development 125:3509–3519.

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