Histone Code Modifications on Pluripotential Nuclei of Reprogrammed Somatic Cells

REFERENCES

• Armstrong, J. A., and Emerson B. M.. 1998. Transcription of chromatin: these are complex times. Curr. Opin. Genet. Dev. 8:165–172.
   PubMed Web of Science ®Google Scholar
• Beisel, C., Imhof A., Greene J., Kremmer E., and Sauer F.. 2002. Histone methylation by the Drosophila epigenetic transcriptional regulator Ash1. Nature 419:857–862.
   PubMed Web of Science ®Google Scholar
• Ben-Shushan, E., Pikarsky E., Klar A., and Bergman Y.. 1993. Extinction of Oct-3/4 gene expression in embryonal carcinoma × fibroblast somatic cell hybrids is accompanied by changes in the methylation status, chromatin structure, and transcriptional activity of the Oct-3/4 upstream region. Mol. Cell. Biol. 13:891–901.
   PubMed Web of Science ®Google Scholar
• Boiani, M., Eckardt S., Scholer H. R., and McLaughlin K. J.. 2002. Oct4 distribution and level in mouse clones: consequences for pluripotency. Genes Dev. 16:1209–1219.
   PubMed Web of Science ®Google Scholar
• Bortvin, A., Eggan K., Skaletsky H., Akutsu H., Berry D. L., Yanagimachi R., Page D. C., and Jaenisch R.. 2003. Incomplete reactivation of Oct4-related genes in mouse embryos cloned from somatic nuclei. Development 130:1673–1680.
   PubMed Web of Science ®Google Scholar
• Cairns, B. R. 1998. Chromatin remodeling machines: similar motors, ulterior motives. Trends Biochem. Sci. 23:20–25.
   PubMedGoogle Scholar
• Cao, R., Wang L., Wang H., Xia L., Erdjument-Bromage H., Tempst P., Jones R. S., and Zhang Y.. 2002. Role of histone H3 lysine 27 methylation in Polycomb-group silencing. Science 298:1039–1043.
   PubMed Web of Science ®Google Scholar
• Chambers, I., Colby D., Robertson M., Nichols J., Lee S., Tweedie S., and Smith A.. 2003. Functional expression cloning of nanog, a pluripotency sustaining factor in embryonic stem cells. Cell 113:643–655.
   PubMed Web of Science ®Google Scholar
• Czermin, B., Melfi R., McCabe D., Seitz V., Imhof A., and Pirrota V.. 2002. Drosophila enhancer of Zeste/ESC complexes have a histone H3 methyltransferase activity that marks chromosomal Polycomb sites. Cell 111:185–196.
   PubMed Web of Science ®Google Scholar
• Dean, W., Santos F., Stojkovic M., Zakhartchenko V., Walter J., Wolf E., and Reik W.. 2001. Conservation of methylation reprogramming in mammalian development: aberrant reprogramming in cloned embryos. Proc. Natl. Acad. Sci. USA 98:13734–13738.
   PubMed Web of Science ®Google Scholar
• Erhardt, S., Su I. H., Schneider R., Barton S., Perez-Burgos L., Jenuwein T., Kouzarides T., Tarakhovsky A., and Surani M. A.. 2003. Consequences of the depletion of zygotic and embryonic enhancer of zeste 2 during preimplantation mouse development. Development 130:4235–4248.
   PubMed Web of Science ®Google Scholar
• Forejt, J., Gregorova S., Dohnal K., and Nosek J.. 1984. Gene expression of differentiated parent in teratocarcinoma cell hybrids. Repression or reprogramming? Cell Differ. 15:229–234.
   PubMedGoogle Scholar
• Forsberg, E. C., Downs K. M., Christensen H. M., Im H., Nuzzi P. A., and Bresnick E. H.. 2000. Developmentally dynamic histone acetylation pattern of a tissue-specific chromatin domain. Proc. Natl. Acad. Sci. USA 97:14494–14499.
   PubMedGoogle Scholar
• Fry, C. J., and Peterson C. L.. 2001. Chromatin remodeling enzymes: who's on first? Curr. Biol. 11:R185–197.
   PubMed Web of Science ®Google Scholar
• Fujikura, J., Yamato E., Yonemura S., Hosoda K., Masui S., Nakano K., Miyazaki J., and Niwa H.. 2002. Differentiation of embryonic stem cells is induced by GATA factors. Genes Dev. 16:784–789.
   PubMed Web of Science ®Google Scholar
• Gidekel, S., and Bergman Y.. 2002. A unique developmental pattern of Oct-3/4 DNA methylation is controlled by a cis-demodification element. J. Biol. Chem. 277:34521–34530.
   PubMed Web of Science ®Google Scholar
• Jackson, J. P., Lindroth A. M., Cao X., and Jacobsen S. E.. 2002. Control of CpNpG DNA methylation by the KRYPTONITE histone H3 methyltransferase. Nature 416:556–560.
   PubMed Web of Science ®Google Scholar
• Kal, A. J., Mahmoudi T., Zak N. B., and Verrijzer C. P.. 2000. The Drosophila brahma complex is an essential coactivator for the trithorax group protein zeste. Genes Dev. 14:1058–1071.
   PubMedGoogle Scholar
• Kimura, H., Tada M., Hatano S., Miyazaki M., Nakatsuji N., and Tada T.. 2002. Chromatin reprogramming of male somatic cell-derived XIST and TSIX in ES hybrid cells. Cytogenet. Genome Res. 99:106–114.
   PubMedGoogle Scholar
• Kingston, R. E., and Narlikar G. J.. 1999. ATP-dependent remodeling and acetylation as regulators of chromatin fluidity. Genes Dev. 13:2339–2352.
   PubMed Web of Science ®Google Scholar
• Kuzmichev, A., Nishioka K., Erdjument-Bromage H., Tempst P., and Reinberg D.. 2002. Histone methyltransferase activity associated with a human multiprotein complex containing the Enhancer of Zeste protein. Genes Dev. 16:2893–2905.
   PubMed Web of Science ®Google Scholar
• Lachner, M., O'Sullivan R. J., and Jenuwein T.. 2003. An epigenetic road map for histone lysine methylation. J. Cell Sci. 116:2117–2124.
   PubMed Web of Science ®Google Scholar
• Laible, G., Wolf A., Dorn R., Reuter G., Nislow C., Lebersorger A., Popkin D., Pillus L., and Jenuwein T.. 1997. Mammalian homologues of the Polycomb-group gene Enhancer of zeste mediate gene silencing in Drosophila heterochromatin and at S. cerevisiae telomeres. EMBO J. 16:3219–3232.
   PubMed Web of Science ®Google Scholar
• Lehnertz, B., Ueda Y., Derick A. A., Braunschweig U., Perez-Burgos L., Kubicek S., Chen T., Li E., Jenuwein T., and Peters A. H.. 2003. Suv39h-mediated histone H3 lysine 9 methylation directs DNA methylation to major satellite repeats at pericentric heterochromatin. Curr. Biol. 13:1192–1200.
   PubMed Web of Science ®Google Scholar
• Litt, M. D., Simpson M., Gaszner M., Allis C. D., and Felsenfeld G.. 2001. Correlation between histone lysine methylation and developmental changes at the chicken beta-globin locus. Science 293:2453–2455.
   PubMedGoogle Scholar
• Lyko, F. 2001. DNA methylation learns to fly. Trends Genet. 17:169–172.
   PubMedGoogle Scholar
• Milne, T. A., Briggs S. D., Brock H. W., Martin M. E., Gibbs D., Allis C. D., and Hess J. L.. 2002. MLL targets SET domain methyltransferase activity to Hox gene promoters. Mol. Cell 10:1107–1117.
   PubMed Web of Science ®Google Scholar
• Mitsui, K., Tokuzawa Y., Itoh H., Segawa K., Murakami M., Takahashi K., Maruyama M., Maeda M., and Yamanaka S.. 2003. The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells. Cell 113:631–642.
   PubMed Web of Science ®Google Scholar
• Nakamura, T., Mori T., Tada S., Krajewski W., Rozovskaia T., Wassell R., Dubois G., Mazo A., Croce C. M., and Canaani E.. 2002. ALL-1 is a histone methyltransferase that assembles a supercomplex of proteins involved in transcriptional regulation. Mol. Cell 10:1119–1128.
   PubMed Web of Science ®Google Scholar
• Nichols, J., Zevnik B., Anastassiadis K., Niwa H., Klewe-Nebenius D., Chambers I., Scholer H., and Smith A.. 1998. Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4. Cell 95:379–391.
   PubMed Web of Science ®Google Scholar
• Nishioka, K., Chuikov S., Sarma K., Erdjument-Bromerge H., Allis C. D., Tempst P., and Reinberg D.. 2002. Set9, a novel histone H3 methyltransferase that facilitates transcription by precluding histone tail modifications required for heterochromatin formation. Genes Dev. 16:479–489.
   PubMed Web of Science ®Google Scholar
• Niwa, H., Miyazaki J., and Smith A. G.. 2000. Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells. Nat. Genet. 24:372–376.
   PubMed Web of Science ®Google Scholar
• Noma, K., Allis C. D., and Grewal S. I.. 2001. Transitions in distinct histone H3 methylation patterns at the heterochromatin domain boundaries. Science 293:1150–1155.
   PubMed Web of Science ®Google Scholar
• Noma, K., and Grewal S. I.. 2002. Histone H3 lysine 4 methylation is mediated by Set1 and promotes maintenance of active chromatin states in fission yeast. Proc. Natl. Acad. Sci. USA 99(Suppl. 4):16438–16445.
   PubMedGoogle Scholar
• O'Carroll, D., Erhardt S., Pagani M., Barton S. C., Surani M. A., and Jenuwein T.. 2001. The polycomb-group gene Ezh2 is required for early mouse development. Mol. Cell. Biol. 21:4330–4336.
   PubMed Web of Science ®Google Scholar
• Papoulas, O., Beek S. J., Moseley S. L., McCallum C. M., Sarte M., Shearn A., and Tamkun J. W.. 1998. The Drosophila trithorax group proteins BRM, ASH1 and ASH2 are subunits of distinct protein complexes. Development 125:3955–3966.
   PubMedGoogle Scholar
• Plath, K., Fang J., Mlynarczyk-Evans S. K., Cao R., Worringer K. A., Wang H., de la Cruz C. C., Otte A. P., Panning B., and Zhang Y.. 2003. Role of histone H3 lysine 27 methylation in X inactivation. Science 300:131–135.
   PubMed Web of Science ®Google Scholar
• Rideout, W. M., 3rd, Wakayama T., Wutz A., Eggan K., Jackson-Grusby L., Dausman J., Yanagimachi R., and Jaenisch R.. 2000. Generation of mice from wild-type and targeted ES cells by nuclear cloning. Nat. Genet. 24:109–110.
   PubMed Web of Science ®Google Scholar
• Rohwedel, J., Kleppisch T., Pich U., Guan K., Jin S., Zuschratter W., Hopf C., Hoch W., Hescheler J., Witzemann V., and Wobus A. M.. 1998. Formation of postsynaptic-like membranes during differentiation of embryonic stem cells in vitro. Exp. Cell Res. 239:214–225.
   PubMedGoogle Scholar
• Santos, F., Zakhartchenko V., Stojkovic M., Peters A., Jenuwein T., Wolf E., Reik W., and Dean W.. 2003. Epigenetic marking correlates with developmental potential in cloned bovine preimplantation embryos. Curr. Biol. 13:1116–11121.
   PubMed Web of Science ®Google Scholar
• Santos-Rosa, H., Schneider R., Bannister A. J., Sherriff J., Bernstein B. E., Emre N. C., Schreiber S. L., Mellor J., and Kouzarides T.. 2002. Active genes are trimethylated at K4 of histone H3. Nature 419:407–411.
   PubMed Web of Science ®Google Scholar
• Santos-Rosa, H., Schneider R., Bernstein B. E., Karabetsou N., Morillon A., Weise C., Schreiber S. L., Mellor J., and Kouzarides T.. 2003. Methylation of histone H3 K4 mediates association of the Isw1p ATPase with chromatin. Mol. Cell 12:1325–1332.
   PubMedGoogle Scholar
• Silva, J., Mak W., Zvetkova I., Appanah R., Nesterova T. B., Webster Z., Peters A. H., Jenuwein T., Otte A. P., and Brockdorff N.. 2003. Establishment of histone H3 methylation on the inactive X chromosome requires transient recruitment of Eed-Enx1 polycomb group complexes. Dev. Cell 4:481–495.
   PubMed Web of Science ®Google Scholar
• Solter, D. 2000. Mammalian cloning: advance and limitations. Nat. Rev. Genet. 1:199–207.
   PubMed Web of Science ®Google Scholar
• Strahl, B. D., Ohba R., Cook R. G., and Allis C. D.. 1999. Methylation of histone H3 at lysine 4 is highly conserved and correlates with transcriptionally active nuclei in Tetrahymena. Proc. Natl. Acad. Sci. USA 96:14967–14972.
   PubMed Web of Science ®Google Scholar
• Tada, M., Morizane A., Kimura H., Kawasaki H., Ainscough J. F., Sasai Y., Nakatsuji N., and Tada T.. 2003. Pluripotency of reprogrammed somatic genomes in embryonic stem hybrid cells. Dev. Dyn. 227:504–510.
   PubMed Web of Science ®Google Scholar
• Tada, M., Tada T., Lefebvre L., Barton S. C., and Surani M. A.. 1997. Embryonic germ cells induce epigenetic reprogramming of somatic nucleus in hybrid cells. EMBO J. 16:6510–6520.
   PubMed Web of Science ®Google Scholar
• Tada, M., Takahama Y., Abe K., Nakatsuji N., and Tada T.. 2001. Nuclear reprogramming of somatic cells by in vitro hybridization with ES cells. Curr. Biol. 11:1553–1558.
   PubMed Web of Science ®Google Scholar
• Tamaru, H., and Selker E. U.. 2001. A histone H3 methyltransferase controls DNA methylation in Neurospora crassa. Nature 414:277–283.
   PubMed Web of Science ®Google Scholar
• Varga-Weisz, P. D., and Becker P. B.. 1998. Chromatin-remodeling factors: machines that regulate? Curr. Opin. Cell Biol. 10:346–353.
   PubMed Web of Science ®Google Scholar
• Wang, H., Cao R., Xia L., Erdjument-Bromerge H., Borchers C., Tempst P., and Zhang Y.. 2001. Purification and functional characterization of a histone H3-lysine 4-specific methyltransferase. Mol. Cell 8:1207–1217.
   PubMed Web of Science ®Google Scholar
• Whitelaw, E., and Martin D. I.. 2001. Retrotransposons as epigenetic mediators of phenotypic variation in mammals. Nat. Genet. 27:361–365.
   PubMed Web of Science ®Google Scholar
• Workman, J. L., and Kingston R. E.. 1998. Alteration of nucleosome structure as a mechanism of transcriptional regulation. Annu. Rev. Biochem. 67:545–579.
   PubMed Web of Science ®Google Scholar
• Wysocka, J., Myers P. M., Myers, Laherty C. D., Eisenman R. N., and Herr W.. 2003. Hum. Sin3 deacetylase and trithorax-related Set1/Ash2 histone H3-K4 methyltransferase are tethered together selectively by the cell-proliferation factor HCF-1. Genes Dev. 17:896–911.
   PubMed Web of Science ®Google Scholar
• Yeom, Y. I., Fuhrmann G., Ovitt C. E., Brehm A., Ohbo K., Gross M., Hubner K., and Scholer H. R.. 1996. Germline regulatory element of Oct-4 specific for the totipotent cycle of embryonal cells. Development 122:881–894.
   PubMed Web of Science ®Google Scholar