Ribosomal S6 Kinase (RSK) Regulates Phosphorylation of Filamin A on an Important Regulatory Site

REFERENCES

• Bonni, A., Brunet A., West A. E., Datta S. R., Takasu M. A., and Greenberg M. E.. 1999. Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms. Science 286:1358–1362.
   PubMed Web of Science ®Google Scholar
• Byers, H. R., Etoh T., Doherty J. R., Sober A. J., and Mihm M. C., Jr. 1991. Cell migration and actin organization in cultured human primary, recurrent cutaneous and metastatic melanoma. Time-lapse and image analysis. Am. J. Pathol. 139:423–435.
   PubMedGoogle Scholar
• Calderwood, D. A., Huttenlocher A., Kiosses W. B., Rose D. M., Woodside D. G., Schwartz M. A., and Ginsberg M. H.. 2001. Increased filamin binding to beta-integrin cytoplasmic domains inhibits cell migration. Nat. Cell Biol. 3:1060–1068.
   PubMed Web of Science ®Google Scholar
• Carroll, R. C., and Gerrard J. M.. 1982. Phosphorylation of platelet actin-binding protein during platelet activation. Blood 59:466–471.
   PubMedGoogle Scholar
• Chen, M., and Stracher A.. 1989. In situ phosphorylation of platelet actin-binding protein by cAMP-dependent protein kinase stabilizes it against proteolysis by calpain. J. Biol. Chem. 264:14282–14289.
   PubMed Web of Science ®Google Scholar
• Chen, R. H., Sarnecki C., and Blenis J.. 1992. Nuclear localization and regulation of erk- and rsk-encoded protein kinases. Mol. Cell. Biol. 12:915–927.
   PubMed Web of Science ®Google Scholar
• Cunningham, C. C., Gorlin J. B., Kwiatkowski D. J., Hartwig J. H., Janmey P. A., Byers H. R., and Stossel T. P.. 1992. Actin-binding protein requirement for cortical stability and efficient locomotion. Science 255:325–327.
   PubMed Web of Science ®Google Scholar
• Dalby, K. N., Morrice N., Caudwell F. B., Avruch J., and Cohen P.. 1998. Identification of regulatory phosphorylation sites in mitogen-activated protein kinase (MAPK)-activated protein kinase-1a/p90rsk that are inducible by MAPK. J. Biol. Chem. 273:1496–1505.
   PubMed Web of Science ®Google Scholar
• Davies, P., Shizuta Y., Olden K., Gallo M., and Pastan I.. 1977. Phosphorylation of filamin and other proteins in cultured fibroblasts. Biochem. Biophys. Res. Commun. 74:300–307.
   PubMedGoogle Scholar
• Faulkner, G., Pallavicini A., Comelli A., Salamon M., Bortoletto G., Ievolella C., Trevisan S., Kojic S., Dalla Vecchia F., Laveder P., Valle G., and Lanfranchi G.. 2000. FATZ, a filamin-, actinin-, and telethonin-binding protein of the Z-disc of skeletal muscle. J. Biol. Chem. 275:41234–41242.
   PubMed Web of Science ®Google Scholar
• Fisher, T. L., and Blenis J.. 1996. Evidence for two catalytically active kinase domains in pp90rsk. Mol. Cell. Biol. 16:1212–1219.
   PubMed Web of Science ®Google Scholar
• Flanagan, L. A., Chou J., Falet H., Neujahr R., Hartwig J. H., and Stossel T. P.. 2001. Filamin A, the Arp2/3 complex, and the morphology and function of cortical actin filaments in human melanoma cells. J. Cell Biol. 155:511–517.
   PubMedGoogle Scholar
• Fox, J. W., Lamperti E. D., Eksioglu Y. Z., Hong S. E., Feng Y., Graham D. A., Scheffer I. E., Dobyns W. B., Hirsch B. A., Radtke R. A., Berkovic S. F., Huttenlocher P. R., and Walsh C. A.. 1998. Mutations in filamin 1 prevent migration of cerebral cortical neurons in human periventricular heterotopia. Neuron 21:1315–1325.
   PubMed Web of Science ®Google Scholar
• Frodin, M., and Gammeltoft S.. 1999. Role and regulation of 90 kDa ribosomal S6 kinase (RSK) in signal transduction. Mol. Cell. Endocrinol. 151:65–77.
   PubMed Web of Science ®Google Scholar
• Ito, T., Suzuki A., and Stossel T. P.. 1992. Regulation of water flow by actin-binding protein-induced actin gelatin. Biophys. J. 61:1301–1305.
   PubMedGoogle Scholar
• Jay, D., Garcia E. J., Lara J. E., Medina M. A., and de la Luz Ibarra M.. 2000. Determination of a cAMP-dependent protein kinase phosphorylation site in the C-terminal region of human endothelial actin-binding protein. Arch. Biochem. Biophys. 377:80–84.
   PubMed Web of Science ®Google Scholar
• Jensen, C. J., Buch M. B., Krag T. O., Hemmings B. A., Gammeltoft S., and Frodin M.. 1999. 90-kDa ribosomal S6 kinase is phosphorylated and activated by 3-phosphoinositide-dependent protein kinase-1. J. Biol. Chem. 274:27168–27176.
   PubMed Web of Science ®Google Scholar
• Kawamoto, S., and Hidaka H.. 1984. Ca2+-activated, phospholipid-dependent protein kinase catalyzes the phosphorylation of actin-binding proteins. Biochem. Biophys. Res. Commun. 118:736–742.
   PubMedGoogle Scholar
• Nakamura, F., Osborn E., Janmey P. A., and Stossel T. P.. 2002. Comparison of filamin A-induced cross-linking and Arp2/3 complex-mediated branching on the mechanics of actin filaments. J. Biol. Chem. 277:9148–9154.
   PubMedGoogle Scholar
• Ohta, Y., and Hartwig J. H.. 1995. Actin filament cross-linking by chicken gizzard filamin is regulated by phosphorylation in vitro. Biochemistry 34:6745–6754.
   PubMedGoogle Scholar
• Ohta, Y., and Hartwig J. H.. 1996. Phosphorylation of actin-binding protein 280 by growth factors is mediated by p90 ribosomal protein S6 kinase. J. Biol. Chem. 271:11858–11864.
   PubMedGoogle Scholar
• Ohta, Y., Suzuki N., Nakamura S., Hartwig J. H., and Stossel T. P.. 1999. The small GTPase RalA targets filamin to induce filopodia. Proc. Natl. Acad. Sci. USA 96:2122–2128.
   PubMed Web of Science ®Google Scholar
• Richards, S. A., Dreisbach V. C., Murphy L. O., and Blenis J.. 2001. Characterization of regulatory events associated with membrane targeting of p90 ribosomal S6 kinase 1. Mol. Cell. Biol. 21:7470–7480.
   PubMed Web of Science ®Google Scholar
• Richards, S. A., Fu J., Romanelli A., Shimamura A., and Blenis J.. 1999. Ribosomal S6 kinase 1 (RSK1) activation requires signals dependent on and independent of the MAP kinase ERK. Curr. Biol. 9:810–820.
   PubMedGoogle Scholar
• Sheen, V. L., Feng Y., Graham D., Takafuta T., Shapiro S. S., and Walsh C. A.. 2002. Filamin A and filamin B are co-expressed within neurons during periods of neuronal migration and can physically interact. Hum. Mol. Genet. 11:2845–2854.
   PubMed Web of Science ®Google Scholar
• Shimamura, A., Ballif B. A., Richards S. A., and Blenis J.. 2000. Rsk1 mediates a MEK-MAP kinase cell survival signal. Curr. Biol. 10:127–135.
   PubMed Web of Science ®Google Scholar
• Stephens, L., Anderson K., Stokoe D., Erdjument-Bromage H., Painter G. F., Holmes A. B., Gaffney P. R., Reese C. B., McCormick F., Tempst P., Coadwell J., and Hawkins P. T.. 1998. Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B. Science 279:710–714.
   PubMed Web of Science ®Google Scholar
• Stossel, T. P., Condeelis J., Cooley L., Hartwig J. H., Noegel A., Schleicher M., and Shapiro S. S.. 2001. Filamins as integrators of cell mechanics and signalling. Nat. Rev. Mol. Cell Biol. 2:138–145.
   PubMed Web of Science ®Google Scholar
• Sutherland, C., Campbell D. G., and Cohen P.. 1993. Identification of insulin-stimulated protein kinase-1 as the rabbit equivalent of rskmo-2: identification of two threonines phosphorylated during activation by mitogen-activated protein kinase. Eur. J. Biochem. 212:581–588.
   PubMedGoogle Scholar
• Takada, F., Vander Woude D. L., Tong H. Q., Thompson T. G., Watkins S. C., Kunkel L. M., and Beggs A. H.. 2001. Myozenin: an alpha-actinin- and gamma-filamin-binding protein of skeletal muscle Z lines. Proc. Natl. Acad. Sci. USA 98:1595–1600.
   PubMed Web of Science ®Google Scholar
• Takafuta, T., Wu G., Murphy G. F., and Shapiro S. S.. 1998. Human β-filamin is a new protein that interacts with the cytoplasmic tail of glycoprotein Ibα. J. Biol. Chem. 273:17531–17538.
   PubMed Web of Science ®Google Scholar
• Tan, Y., Ruan H., Demeter M. R., and Comb M. J.. 1999. p90RSK blocks Bad-mediated cell death via a protein kinase C-dependent pathway. J. Biol. Chem. 274:34859–34867.
   PubMed Web of Science ®Google Scholar
• Thompson, T. G., Chan Y. M., Hack A. A., Brosius M., Rajala M., Lidov H. G., McNally E. M., Watkins S., and Kunkel L. M.. 2000. Filamin 2 (FLN2): a muscle-specific sarcoglycan interacting protein. J. Cell Biol. 148:115–126.
   PubMed Web of Science ®Google Scholar
• Tigges, U., Koch B., Wissing J., Jockusch B. M., and Ziegler W. H.. 2003. The F-actin cross-linking and focal adhesion protein filamin A is a ligand and in vivo substrate for protein kinase C alpha. J. Biol. Chem. 278:23561–23569.
   PubMed Web of Science ®Google Scholar
• Trivier, E., De Cesare D., Jacquot S., Pannetier S., Zackai E., Young I., Mandel J. L., Sassone-Corsi P., and Hanauer A.. 1996. Mutations in the kinase Rsk-2 associated with Coffin-Lowry syndrome. Nature 384:567–570.
   PubMedGoogle Scholar
• Vadlamudi, R. K., Li F., Adam L., Nguyen D., Ohta Y., Stossel T. P., and Kumar R.. 2002. Filamin is essential in actin cytoskeletal assembly mediated by p21-activated kinase 1. Nat. Cell Biol. 4:681–690.
   PubMed Web of Science ®Google Scholar
• van der Ven, P. F., Wiesner S., Salmikangas P., Auerbach D., Himmel M., Kempa S., Hayess K., Pacholsky D., Taivainen A., Schroder R., Carpen O., and Furst D. O.. 2000. Indications for a novel muscular dystrophy pathway: γ-filamin, the muscle-specific filamin isoform, interacts with myotilin. J. Cell Biol. 151:235–248.
   PubMedGoogle Scholar
• Vik, T. A., and Ryder J. W.. 1997. Identification of serine 380 as the major site of autophosphorylation of Xenopus pp90rsk. Biochem. Biophys. Res. Commun. 235:398–402.
   PubMedGoogle Scholar
• Wallach, D., Davies P. J., and Pastan I.. 1978. Cyclic AMP-dependent phosphorylation of filamin in mammalian smooth muscle. J. Biol. Chem. 253:4739–4745.
   PubMedGoogle Scholar
• Williams, M. R., Arthur J. S., Balendran A., van der Kaay J., Poli V., Cohen P., and Alessi D. R.. 2000. The role of 3-phosphoinositide-dependent protein kinase 1 in activating AGC kinases defined in embryonic stem cells. Curr. Biol. 10:439–448.
   PubMed Web of Science ®Google Scholar
• Wu, M. P., Jay D., and Stracher A.. 1994. Existence of multiple phosphorylated forms of human platelet actin binding protein. Cell. Mol. Biol. Res. 40:351–357.
   PubMedGoogle Scholar
• Zhuang, Q. Q., Rosenberg S., Lawrence J., and Stracher A.. 1984. Role of actin binding protein phosphorylation in platelet cytoskeleton assembly. Biochem. Biophys. Res. Commun. 118:508–513.
   PubMed Web of Science ®Google Scholar