22
Views
84
CrossRef citations to date
0
Altmetric
Gene Expression

Functional Cooperation between CCAAT/Enhancer-Binding Proteins and the Vitamin D Receptor in Regulation of 25-Hydroxyvitamin D3 24-Hydroxylase

, , , , , , , & show all
Pages 472-487 | Received 12 Mar 2004, Accepted 07 Sep 2004, Published online: 27 Mar 2023

REFERENCES

  • Affymetrix Inc. 2002. GeneChip expression analysis. Technical manual. Affymetrix Inc., Santa Clara, Calif.
  • Alam, T., M. R. An, R. C. Mifflin, C. C. Hsieh, X. Ge, and J. Papaconstantinou. 1993. trans-activation of the alpha 1-acid glycoprotein gene acute phase responsive element by multiple isoforms of C/EBP and glucocorticoid receptor. J. Biol. Chem. 268:15681–15688.
  • Alam, T., M. R. An, and J. Papaconstantinou. 1992. Differential expression of three C/EBP isoforms in multiple tissues during the acute phase response. J. Biol. Chem. 267:5021–5024.
  • Armbrecht, H. J., R. H. Wasserman, and M. E. Bruns. 1979. Effect of 1,25-dihydroxyvitamin D3 on intestinal calcium absorption in strontium-fed rats. Arch. Biochem. Biophys. 192:466–473.
  • Austen, M., B. Luscher, and J. M. Luscher-Firzlaff. 1997. Characterization of the transcriptional regulator YY1. The bipartite transactivation domain is independent of interaction with the TATA box-binding protein, transcription factor IIB, TAFII55, or cAMP-responsive element-binding protein (CPB)-binding protein. J. Biol. Chem. 272:1709–1717.
  • Ausubel, F. M., R. Bent, R. E. Kingston, D. D. Moore, J. G. Steidman, J. A. Smith, and K. Struhl. 2002. Current protocols in molecular biology. Wiley, New York, N.Y.
  • Barletta, F., L. P. Freedman, and S. Christakos. 2002. Enhancement of VDR-mediated transcription by phosphorylation: correlation with increased interaction between the VDR and DRIP205, a subunit of the VDR-interacting protein coactivator complex. Mol. Endocrinol. 16:301–314.
  • Bauknecht, T., R. H. See, and Y. Shi. 1996. A novel C/EBP beta-YY1 complex controls the cell-type-specific activity of the human papillomavirus type 18 upstream regulatory region. J. Virol. 70:7695–7705.
  • Billiard, J., Y. Umayahara, K. Wiren, M. Centrella, T. L. McCarthy, and P. Rotwein. 2001. Regulated nuclear-cytoplasmic localization of CCAAT/enhancer-binding protein delta in osteoblasts. J. Biol. Chem. 276:15354–15361.
  • Boruk, M., J. G. Savory, and R. J. Hache. 1998. AF-2-dependent potentiation of CCAAT enhancer binding protein beta-mediated transcriptional activation by glucocorticoid receptor. Mol. Endocrinol. 12:1749–1763.
  • Bradford, M. M. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:248–254.
  • Breed, D. R., L. R. Margraf, J. L. Alcorn, and C. R. Mendelson. 1997. Transcription factor C/EBPdelta in fetal lung: developmental regulation and effects of cyclic adenosine 3′,5′-monophosphate and glucocorticoids. Endocrinology 138:5527–5534.
  • Chinery, R., J. A. Brockman, D. T. Dransfield, and R. J Coffey. 1997. Antioxidant-induced nuclear translocation of CCAAT/enhancer-binding protein beta. A critical role for protein kinase A-mediated phosphorylation of Ser299. J. Biol. Chem. 272:30356–30361.
  • Christakos, S., P. Dhawan, Y. Liu, X. Peng, and A. Porta. 2003. New insights into the mechanisms of vitamin D action. J. Cell Biochem. 88:695–705.
  • Delany, A. M., D. Durant, and E. Canalis. 2001. Glucocorticoid suppression of IGF I transcription in osteoblasts. Mol. Endocrinol. 15:1781–1789.
  • Divieti, P., B. Lanske, H. M. Kronenberg, and F. R. Bringhurst. 1998. Conditionally immortalized murine osteoblasts lacking the type 1 PTH/PTHrP receptor. J. Bone Miner. Res. 13:1835–1845.
  • Dwivedi, P. P., J. L. Omdahl, I. Kola, D. A. Hume, and B. K. May. 2000. Regulation of rat cytochrome P450C24 (CYP24) gene expression. Evidence for functional cooperation of Ras-activated Ets transcription factors with the vitamin D receptor in 1,25-dihydroxyvitamin D(3)-mediated induction. J. Biol. Chem. 275:47–55.
  • Eckner, R., M. E. Ewen, D. Newsome, M. Gerdes, J. A. DeCaprio, J. B. Lawrence, and D. M. Livingston. 1994. Molecular cloning and functional analysis of the adenovirus E1A-associated 300-kD protein (p300) reveals a protein with properties of a transcriptional adaptor. Genes Dev. 8:869–884.
  • Gorman, C. M., L. F. Moffat, and B. H. Howard. 1982. Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells. Mol. Cell. Biol. 2:1044–1051.
  • Gupta, A. K., and B. C. Kone. 1999. CCAAT/enhancer binding protein-beta trans-activates murine nitric oxide synthase 2 gene in an MTAL cell line. Am. J. Physiol. 276:F599–F605.
  • Gutierrez, S., A. Javed, D. K. Tennant, M. van Rees, M. Montecino, G. S. Stein, J. L. Stein, and J. B. Lian. 2002. CCAAT/enhancer-binding proteins (C/EBP) beta and delta activate osteocalcin gene transcription and synergize with Runx2 at the C/EBP element to regulate bone-specific expression. J. Biol. Chem. 277:1316–1323.
  • Hanson, R. W. 1998. Biological role of the isoforms of C/EBP minireview series. J. Biol. Chem. 273:28543.
  • Harrison, J. R., P. L. Kelly, and C. C. Pilbeam. 2000. Involvement of CCAAT enhancer binding protein transcription factors in the regulation of prostaglandin G/H synthase 2 expression by interleukin-1 in osteoblastic MC3T3-E1 cells. J. Bone Miner. Res. 15:1138–1146.
  • Huening, M., G. Yehia, C. A. Molina, and S. Christakos. 2002. Evidence for a regulatory role of inducible cAMP early repressor in protein kinase A-mediated enhancement of vitamin D receptor expression and modulation of hormone action. Mol. Endocrinol. 16:2052–2064.
  • Ji, C., W. Chang, M. Centrella, and T. L. McCarthy. 2003. Activation domains of CCAAT enhancer binding protein delta: regions required for native activity and prostaglandin E2-dependent transactivation of insulin-like growth factor I gene expression in rat osteoblasts. Mol. Endocrinol. 17:1834–1843.
  • Jurutka, P. W., G. K. Whitfield, J. C. Hsieh, P. D. Thompson, C. A. Haussler, and M. R. Haussler. 2001. Molecular nature of the vitamin D receptor and its role in regulation of gene expression. Rev. Endocr. Metab. Disord. 2:203–216.
  • Kerry, D. M., P. P. Dwivedi, C. N. Hahn, H. A. Morris, J. L. Omdahl, and B. K. May. 1996. Transcriptional synergism between vitamin D-responsive elements in the rat 25-hydroxyvitamin D3 24-hydroxylase (CYP24) promoter. J. Biol. Chem. 271:29715–29721.
  • Kovacs, K. A., M. Steinmann, P. J. Magistretti, O. Halfon, and J. R. Cardinaux. 2003. CCAAT/enhancer-binding protein family members recruit the coactivator CREB-binding protein and trigger its phosphorylation. J. Biol. Chem. 278:36959–36965.
  • Krishnan, A. V., S. D. Cramer, F. R. Bringhurst, and D. Feldman. 1995. Regulation of 1,25-dihydroxyvitamin D3 receptors by parathyroid hormone in osteoblastic cells: role of second messenger pathways. Endocrinology 136:705–712.
  • Kurokawa, R., D. Kalafus, M. H. Ogliastro, C. Kioussi, L. Xu, J. Torchia, M. G. Rosentfeld, and C. K. Glass. 1998. Differential use of CREB binding protein-coactivator complexes. Science 279:700–703.
  • Lee, Y. H., S. C. Williams, M. Baer, E. Sterneck, F. J. Gonzalez, and P. F. Johnson. 1997. The ability of C/EBP beta but not C/EBP alpha to synergize with an Sp1 protein is specified by the leucine zipper and activation domain. Mol. Cell. Biol. 17:2038–2047.
  • Li, H., and S. Christakos. 1991. Differential regulation by 1,25-dihydroxyvitamin D3 of calbindin-D9k and calbindin-D28k gene expression in mouse kidney. Endocrinology 128:2844–2852.
  • Liu, X., Q. T. Wall, L. Taylor, and N. P. Curthoys. 2001. C/EBPbeta contributes to cAMP-activated transcription of phosphoenolpyruvate carboxykinase in LLC-PK(1)-F+ cells. Am. J. Physiol. Renal Physiol. 281:F649–F657.
  • MacDonald, P. N., T. A. Baudino, H. Tokumaru, D. R. Dowd, and C. Zhang. 2001. Vitamin D receptor and nuclear receptor coactivators: crucial interactions in vitamin D-mediated transcription. Steroids 66:171–176.
  • Matsuno, F., S. Chowdhury, T. Gotoh, K. Iwase, H. Matsuzaki, K. Takatsuki, M. Mori, and M. Takiguchi. 1996. Induction of the C/EBP beta gene by dexamethasone and glucagon in primary-cultured rat hepatocytes. J. Biochem. (Tokyo) 119:524–532.
  • Matsusaka, T., K. Fujikawa, Y. Nishio, N. Mukaida, K. Matsushima, T. Kishimoto, and S. Akira. 1993. Transcription factors NF-IL6 and NF-kappa B synergistically activate transcription of the inflammatory cytokines, interleukin 6 and interleukin 8. Proc. Natl. Acad. Sci. USA 90:10193–10197.
  • McCarthy, T. L., M. Centrella, and E. Canalis. 1988. Further biochemical and molecular characterization of primary rat parietal bone cell cultures. J. Bone Miner. Res. 3:401–408.
  • McCarthy, T. L., C. Ji, Y. Chen, K. Kim, and M. Centrella. 2000. Time- and dose-related interactions between glucocorticoid and cyclic adenosine 3′,5′-monophosphate on CCAAT/enhancer-binding protein-dependent insulin-like growth factor I expression by osteoblasts. Endocrinology 141:127–137.
  • McCarthy, T. L., C. Ji, Y. Chen, K. K. Kim, M. Imagawa, Y. Ito, and M. Centrella. 2000. Runt domain factor (Runx)-dependent effect on CCAAT/enhancer-binding protein δ expression and activity in osteoblasts. J. Biol. Chem. 275:21746–21753.
  • McCarthy, T. L., C. Ji, and M. Centrella. 2000. Links among growth factors, hormones and nuclear factors with essential roles in bone formation. Crit. Rev. Oral Biol. Med. 11:409–422.
  • Mellon, P. L., C. H. Clegg, L. A. Correll, and G. S. McKnight. 1989. Regulation of transcription by cyclic AMP-dependent protein kinase. Proc. Natl. Acad. Sci. USA 86:4887–4891.
  • Menendez-Hurtado, A., A. Santos, and A. Perez-Castillo. 2000. Characterization of the promoter region of the rat CCAAT/enhancer-binding protein [alpha] gene and regulation by thyroid hormone in rat immortalized brown adipocytes. Endocrinology 141:4164–4170.
  • Mink, S., B. Haenig, and K. H. Klempnauer. 1997. Interaction and functional collaboration of p300 and C/EBPβ. Mol. Cell. Biol. 17:6609–6617.
  • Miyamoto, K., R. A. Kesterson, H. Yamamoto, Y. Taketani, E. Nishiwaki, S., Tatsumi, Y. Inoue, K. Morita, E. Takeda, and J. W. Pike. 1997. Structural organization of the human vitamin D receptor chromosomal gene and its promoter. Mol. Endocrinol. 11:1165–1179.
  • Nakajima, T., C. Uchida, S. F. Anderson, C. G. Lee, J. Hurwitz, J. D. Parvin, and M. Montminy. 1997. RNA helicase A mediates association of CBP with RNA polymerase II. Cell 90:1107–1112.
  • Niehof, M., M. P. Manns, and C. Trautwein. 1997. CREB controls LAP/C/EBP beta transcription. Mol. Cell. Biol. 17:3600–3613.
  • Nishio, Y., H. Isshiki, T. Kishimoto, and S. Akira. 1993. A nuclear factor for interleukin-6 expression (NF-IL6) and the glucocorticoid receptor synergistically activate transcription of the rat alpha 1-acid glycoprotein gene via direct protein-protein interaction. Mol. Cell. Biol. 13:1854–1862.
  • Ohyama, Y., M. Noshiro, and K. Okuda. 1991. Cloning and expression of cDNA encoding 25-hydroxyvitamin D3 24-hydroxylase. FEBS Lett. 278:195–198.
  • Ohyama, Y., K. Ozono, M. Uchida, M. Yoshimura, T. Shinki, T. Suda, and O. Yamamoto. 1996. Functional assessment of two vitamin D-responsive elements in the rat 25-hydroxyvitamin D3 24-hydroxylase gene. J. Biol. Chem. 271:30381–30385.
  • Omdahl, J. L., H. A Morris, and B. K. May. 2002. Hydroxylase enzymes of the vitamin D pathway: expression, function, and regulation. Annu. Rev. Nutr. 22:139–166.
  • Osada, S., H. Yamamoto, T. Nishihara, and M. Imagwa. 1997. DNA binding specificity of the CCAAT/ enhancer-binding protein transcription factor family. J. Biol. Chem. 271:3891–3896.
  • Park, E. A., S. Song, C. Vinson, and W. J. Roesler. 1999. Role of CCAAT enhancer-binding protein beta in the thyroid hormone and cAMP induction of phosphoenolpyruvate carboxykinase gene transcription. J. Biol. Chem. 274:211–217.
  • Qiu, Y., A. Sharma, and R. Stein. 1998. p300 mediates transcriptional stimulation by the basic helix-loop-helix activators of the insulin gene. Mol. Cell. Biol. 18:2957–2964.
  • Rachez, C., and L. P. Freedman. 2000. Mechanisms of gene regulation by vitamin D(3) receptor: a network of coactivator interactions. Gene 246:9–21.
  • Rachez, C., B. D. Lemon, Z. Suldan, V. Bromleigh, M. Gamble, A. M. Naar, H. Erdjument-Bromage, P. Tempst, and L. P. Freedman. 1999. Ligand-dependent transcription activation by nuclear receptors requires the DRIP complex. Nature 398:824–828.
  • Ramji, D. P., and P. Foka. 2002. CCAAT/enhancer-binding proteins: structure, function and regulation. Biochem. J. 365:561–575.
  • Raval-Pandya, M., P. Dhawan, F. Barletta, and S. Christakos. 2001. YY1 represses vitamin D receptor-mediated 25-hydroxyvitamin D(3)24-hydroxylase transcription: relief of repression by CREB-binding protein. Mol. Endocrinol. 15:1035–1046.
  • Ray, B. K., and A. Ray. 1994. Expression of the gene encoding alpha 1-acid glycoprotein in rabbit liver under acute-phase conditions involves induction and activation of beta and delta CCAAT-enhancer-binding proteins. Eur. J. Biochem. 222:891–900.
  • Reddy, G. S., and K. Y. Tserng. 1989. Calcitroic acid, end product of renal metabolism of 1,25-dihydroxyvitamin D3 through C-24 oxidation pathway. Biochemistry 28:1763–1769.
  • Roesler, W. J., E. A. Park, and P. J. McFie. 1998. Characterization of CCAAT/enhancer-binding protein alpha as a cyclic AMP-responsive nuclear regulator. J. Biol. Chem. 273:14950–14957.
  • Schwarz, E. J., M. J. Reginato, D. Shao, S. L. Krakow, and M. A. Lazar. 1997. Retinoic acid blocks adipogenesis by inhibiting C/EBP beta-mediated transcription. Mol. Cell. Biol. 17:1552–1561.
  • Screpanti, I., L. Romani, P. Musiani, A. Modesti, E. Fattori, D. Lazzaro, C. Sellitto, S. Scarpa, D. Bellavia, and G. Lattanzio. 1995. Lymphoproliferative disorder and imbalanced T-helper response in C/EBP beta-deficient mice. EMBO J. 14:1932–1941.
  • Song, Y., X. Peng, A. Porta, H. Takanaga, J. B. Peng, M. A. Hediger, J. C. Fleet, and S. Christakos. 2003. Calcium transporter 1 and epithelial calcium channel messenger ribonucleic acid are differentially regulated by 1,25 dihydroxyvitamin D3 in the intestine and kidney of mice. Endocrinology 144:3885–3894.
  • St.-Arnaud, R., A. Arabian, R. Travers, F. Barletta, M. Raval-Pandya, K. Chapin, J. Depovere, C. Mathieu, S. Christakos, M. B. Demay, and F. H. Glorieux. 2000. Deficient mineralization of intramembranous bone in vitamin D-24-hydroxylase-ablated mice is due to elevated 1,25-dihydroxyvitamin D and not to the absence of 24,25-dihydroxyvitamin D. Endocrinology 141:2658–2666.
  • Stein, B., and M. X. Yang. 1995. Repression of the interleukin-6 promoter by estrogen receptor is mediated by NF-κB and C/EBPβ. Mol. Cell. Biol. 15:4971–4979.
  • Umayahara, Y., J. Billiard, C. Ji, M. Centrella, T. L. McCarthy, and P. Rotwein. 1999. CCAAT/enhancer-binding protein delta is a critical regulator of insulin-like growth factor-I gene transcription in osteoblasts. J. Biol. Chem. 274:10609–10617.
  • van Leeuwen, J. P., J. C. Birkenhager, G. C. van den Bemd, and H. A. Pols. 1996. Evidence for coordinated regulation of osteoblast function by 1,25-dihydroxyvitamin D3 and parathyroid hormone. Biochim. Biophys. Acta 1312:54–62.
  • Varghese, S., S. Lee, Y. C. Huang, and S. Christakos. 1988. Analysis of rat vitamin D-dependent calbindin-D28k gene expression. J. Biol. Chem. 263:9776–9784.
  • Wilson, H. L., and W. J. Roesler. 2002. CCAAT/enhancer binding proteins: do they possess intrinsic cAMP-inducible activity. Mol. Cell Endocrinol. 188:15–20.
  • Wyszomierski, S. L., and J. M. Rosen. 2001. Cooperative effects of STAT5 (signal transducer and activator of transcription 5) and C/EBP beta (CCAAT/enhancer-binding protein-beta) on beta-casein gene transcription are mediated by the glucocorticoid receptor. Mol. Endocrinol. 15:228–240.
  • Yamada, K., D. T. Duong, D. K. Scott, J. C. Wang, and D. K. Granner. 1999. CCAAT/enhancer-binding protein beta is an accessory factor for the glucocorticoid response from the cAMP response element in the rat phosphoenolpyruvate carboxykinase gene promoter. J. Biol. Chem. 274:5880–5887.
  • Yang, W., S. J. Hyllner, and S. Christakos. 2001. Interrelationship between signal transduction pathways and 1,25(OH)2D3 in UMR106 osteoblastic cells. Am. J. Physiol. Endocrinol. Metab. 281:E162–E170.
  • Yeh, W. C., Z. Cao, M. Classon, and S. L. McKnight. 1994. Cascade regulation of terminal adipocyte differentiation by three members of C/EBP family of leucine zipper proteins. Genes Dev. 9:168–181.
  • Zhang, D. E., C. J. Hetherington, S. Meyers, K. L. Rhoades, C. J. Larson, H. M. Chen, S. W. Hiebert, and D. G. Tenen. 1996. CCAAT enhancer-binding protein (C/EBP) and AML1 (CBF α2) synergistically activate the macrophage colony-stimulating factor receptor promoter. Mol. Cell. Biol. 16:1231–1240.
  • Zierold, C., G. Reinholz, J. A. Mings, J. M. Prahl, and H. F. DeLuca. 2000. Regulation of porcine 1,25-dihydroxyvitamin D3-24-hydroxylase (Cyp24) by 1,25-dihydroxyvitamin D3 and parathyroid hormone in AOK-B50 cells. Arch. Biochem. Biophys. 381:323–327.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.