MrgX Is Not Essential for Cell Growth and Development in the Mouse

REFERENCES

• Akhtar, A., D. Zink, and P. B. Becker. 2000. Chromodomains are protein-RNA interaction modules. Nature 407:405–409.
   PubMed Web of Science ®Google Scholar
• Bertram, M. J., N. G. Berube, X. Hang-Swanson, Q. Ran, J. K. Leung, S. Bryce, K. Spurgers, R. J. Bick, A. Baldini, Y. Ning, L. J. Clark, E. K. Parkinson, J. C. Barrett, J. R. Smith, and O. M. Pereira-Smith. 1999. Identification of a gene that reverses the immortal phenotype of a subset of cells and is a member of a novel family of transcription factor-like genes. Mol. Cell. Biol. 19:1479–1485.
   PubMedGoogle Scholar
• Bertram, M. J., and O. M. Pereira-Smith. 2001. Conservation of the MORF4 related gene family: identification of a new chromo domain subfamily and novel protein motif. Gene 266:111–121.
   PubMed Web of Science ®Google Scholar
• Brehm, A., K. R. Tufteland, R. Aasland, and P. B. Becker. 2004. The many colours of chromodomain. Bioessays 26:133–140.
   PubMed Web of Science ®Google Scholar
• Cai, Y., J. Jin, L. Florens, S. K. Swanson, T. Kusch, B. Li, J. L. Workman, M. P. Washburn, R. C. Conaway, and J. W. Conaway. 2005. The mammalian YL1 protein is a shared subunit of the TRRAP/TIP60 histone acetyltransferase and SRCAP complexes. J. Biol. Chem. 280:13665–13670.
   PubMed Web of Science ®Google Scholar
• Cai, Y., J. Jin, C. Tomomori-Sato, S. Sato, I. Sorokina, T. J. Parmely, R. C. Conaway, and J. W. Conaway. 2003. Identification of new subunits of the multiprotein mammalian TRRAP/TIP60-containing histone acetyltransferase complex. J. Biol. Chem. 278:42733–42736.
   PubMed Web of Science ®Google Scholar
• Cavalli, G., and R. Paro. 1998. Chromo-domain proteins: linking chromatin structure to epigenetic regulation. Curr. Opin. Cell Biol. 10:354–360.
   PubMedGoogle Scholar
• Doyon, Y., and J. Cote. 2004. The highly conserved and multifunctional NuA4 complex. Curr. Opin. Genet. Dev. 14:147–154.
   PubMed Web of Science ®Google Scholar
• Doyon, Y., W. Selleck, W. S. Lane, S. Tan, and J. Cote. 2004. Structural and functional conservation of the NuA4 histone acetyltransferase complex from yeast to humans. Mol. Cell. Biol. 24:1884–1896.
   PubMed Web of Science ®Google Scholar
• Eriksson, M., W. T. Brown, L. B. Gordon, M. W. Glynn, J. Singer, L. Scott, M. R. Erdos, C. M. Robbins, T. Y. Moses, P. Berglund, A. Dutra, E. Pak, S. Durkin, A. B. Csoka, M. Boehnke, T. W. Glover, and F. S. Collins. 2003. Recurrent de nono point mutations in lamin A cause Hutchinson-Gilford progeria syndrome. Nature 423:293–298.
   PubMed Web of Science ®Google Scholar
• Hayflick, L., and P. S. Moorhead. 1961. The serial cultivation of human diploid cell strains. Exp. Cell Res. 25:585–621.
   PubMed Web of Science ®Google Scholar
• He, D., J. A. Nickerson, and S. Penman. 1990. Core filaments of the nuclear matrix. J. Cell Biol. 110:569–580.
   PubMed Web of Science ®Google Scholar
• Herrera, R. E., V. P. Sah, B. O. Williams, T. P. Makela, R. A. Weinberg, and T. Jacks. 1996. Altered cell cycle kinetics, gene expression, and G1 restriction point regulation in Rb-deficient fibroblasts. Mol. Cell. Biol. 16:2402–2407.
   PubMedGoogle Scholar
• Hurford, R. K. J., D. Cobrinik, M.-H. Lee, and N. Dyson. 1997. pRb and p107/p130 are required for the regulated expression of different sets of E2F responsive genes. Genes Dev. 11:1447–1463.
   PubMed Web of Science ®Google Scholar
• Ikura, T., V. V. Ogryzko, M. Grigoriev, R. Groisman, J. Wang, M. Horikoshi, R. Scully, J. Qin, and Y. Nakatani. 2000. Involvement of the TIP60 histone acetylase complex in DNA repair and apoptosis. Cell 102:463–473.
   PubMed Web of Science ®Google Scholar
• Jones, D. O., I. G. Cowell, and P. B. Singh. 2000. Mammalian chromodomain proteins: their role in genome organisation and expression. Bioessays 22:124–137.
   PubMed Web of Science ®Google Scholar
• Koonin, E. V., S. Zhou, and J. C. Lucchesi. 1995. The chromo superfamily: new members, duplication of the chromodomain and possible role in delivering transcription regulators to chromatin. Nucleic Acids Res. 23:4229–4233.
   PubMed Web of Science ®Google Scholar
• Lachner, M., D. O'Carroll, S. Rea, K. Mechtler, and T. Jenuwein. 2001. Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins. Nature 410:116–120.
   PubMed Web of Science ®Google Scholar
• Lakso, M., J. G. Pichel, J. R. Gorman, B. Sauer, Y. Okamoto, E. Lee, F. W. Alt, and H. Westphal. 1996. Efficient in vivo manipulation of mouse genomic sequences at the zygote stage. Proc. Natl. Acad. Sci. USA 93:5860–5865.
   PubMed Web of Science ®Google Scholar
• Leung, J. K., N. G. Berube, A. Venable, S. Ahmed, N. Timchenko, and O. M. Pereira-Smith. 2001. MRG15 activates the B-myb promoter through formation of a nuclear complex with the retinoblastoma protein and the novel protein PAM14. J. Biol. Chem. 276:39171–39178.
   PubMedGoogle Scholar
• Mancini, M. A., B. Shan, J. A. Nickerson, S. Penman, and W.-H. Lee. 1994. The retinoblastoma gene product is a cell cycle-dependent, nuclear matrix-associated protein. Proc. Natl. Acad. Sci. USA 91:418–422.
   PubMed Web of Science ®Google Scholar
• Markiewicz, E., T. Dechat, R. Foisner, R. A. Quinlan, and C. J. Hutchison. 2002. Lamin A/C binding protein LAP2α is required for nuclear anchorage of retinoblastoma protein. Mol. Biol. Cell 13:4401–4413.
   PubMed Web of Science ®Google Scholar
• Mattout-Drubezki, A., and Y. Gruenbaum. 2003. Dynamic interactions of nuclear lamina proteins with chromatin and transcriptional machinery. Cell. Mol. Life Sci. 60:2053–2063.
   PubMed Web of Science ®Google Scholar
• Matzuk, M. M., M. J. Finegold, J. J. Su, A. J. W. Hsueh, and A. Bradley. 1992. Alpha-inhibin is a tumor suppressor gene with gonadal specificity in mice. Nature 360:313–319.
   PubMed Web of Science ®Google Scholar
• Mounkes, L. C., S. Kozlov, L. Hernandez, T. Sullivan, and C. L. Stewart. 2003. A progeroid syndrome in mice is caused by defects in A-type lamins. Nature 423:298–301.
   PubMed Web of Science ®Google Scholar
• Mounkes, L. C., and C. L. Stewart. 2004. Aging and nuclear organization: lamins and progeria. Curr. Opin. Cell Biol. 16:322–327.
   PubMedGoogle Scholar
• Muchir, A., and H. J. Worman. 2004. The nuclear envelope and human disease. Physiology 19:309–314.
   PubMed Web of Science ®Google Scholar
• Nickerson, J. A. 2001. Experimental observations of a nuclear matrix. J. Cell Sci. 114:460–474.
   Google Scholar
• Pardo, P. S., J. K. Leung, J. C. Lucchesi, and O. M. Pereira-Smith. 2002. MRG15 a novel chromodomain protein is present in two distinct multiprotein complexes involved in transcriptional activation. J. Biol. Chem. 277:50860–50866.
   PubMedGoogle Scholar
• Pollex, R. L., and R. A. Hegele. 2004. Hutchinson-Gilford progeria syndrome. Clin. Genet. 66:375–381.
   PubMed Web of Science ®Google Scholar
• Ran, Q., R. Wadhwa, O. Bischof, S. Venable, J. R. Smith, and O. M. Pereira-Smith. 2001. Characterization of a novel zinc finger gene with increased expression in nondividing normal human cells. Exp. Cell Res. 263:156–162.
   PubMedGoogle Scholar
• Smith, J. R., and O. M. Pereira-Smith. 1996. Replicative senescence: implications for in vivo aging and tumor suppression. Science 273:63–67.
   PubMed Web of Science ®Google Scholar
• Tominaga, K., B. Kirtane, J. G. Jackson, Y. Ikeno, T. Ikeda, C. Hawks, J. R. Smith, M. M. Matzuk, and O. M. Pereira-Smith. 2005. MRG15 regulates embryonic development and cell proliferation. Mol. Cell. Biol. 25:2924–2937.
   PubMedGoogle Scholar
• Tominaga, K., J. K. Leung, P. Rookard, J. Echigo, J. R. Smith, and O. M. Pereira-Smith. 2003. MRGX: a novel transcriptional regulator that exhibits activation or repression of B-myb promoter in a cell type dependent manner. J. Biol. Chem. 278:49618–49624.
   PubMedGoogle Scholar
• Tominaga, K., A. Olgun, J. R. Smith, and O. M. Pereira-Smith. 2002. Genetics of cellular senescence. Mech. Ageing Dev. 123:927–936.
   PubMedGoogle Scholar
• Tominaga, K., and O. M. Pereira-Smith. 2002. The genomic organization, promoter position and expression profile of the mouse MRG15 gene. Gene 294:215–224.
   PubMedGoogle Scholar
• Yochum, G. S., and D. E. Ayer. 2002. Role for the mortality factors MORF4, MRGX, and MRG15 in transcriptional repression via associations with Pf1, mSin3A, and Transducin-Like Enhancer of Split. Mol. Cell. Biol. 22:7868–7876.
   PubMed Web of Science ®Google Scholar
• Zink, D., A. H. Fischer, and J. A. Nickerson. 2004. Nuclear structure in cancer cells. Nature Rev. Cancer 4:677–687.
   PubMed Web of Science ®Google Scholar