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Chromosome Structure and Dynamics

Localized Histone Acetylation and Deacetylation Triggered by the Homologous Recombination Pathway of Double-Strand DNA Repair

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Pages 4903-4913 | Received 30 Dec 2004, Accepted 23 Mar 2005, Published online: 27 Mar 2023

REFERENCES

  • Anderson, J. D., P. T. Lowary, and J. Widom. 2001. Effects of histone acetylation on the equilibrium accessibility of nucleosomal DNA target sites. J. Mol. Biol. 307:977–985.
  • Barlev, N. A., V. Poltoratsky, T. Owen-Hughes, C. Ying, L. Liu, J. L. Workman, and S. L. Berger. 1998. Repression of GCN5 histone acetyltransferase activity via bromodomain-mediated binding and phosphorylation by the Ku-DNA-dependent protein kinase complex. Mol. Cell. Biol. 18:1349–1358.
  • Bennett, C. B., A. L. Lewis, K. K. Baldwin, and M. A. Resnick. 1993. Lethality induced by a single site-specific double-strand break in a dispensable yeast plasmid. Proc. Natl. Acad. Sci. USA 90:5613–5617.
  • Bird, A. W., D. Y. Yu, M. G. Pray-Grant, Q. Qiu, K. E. Harmon, P. C. Megee, P. A. Grant, M. M. Smith, and M. F. Christman. 2002. Acetylation of histone H4 by Esa1 is required for DNA double-strand break repair. Nature 419:411–415.
  • Boulton, S. J., A. Gartner, J. Reboul, P. Vaglio, N. Dyson, D. E. Hill, and M. Vidal. 2002. Combined functional genomic maps of the C. elegans DNA damage response. Science 295:127–131.
  • Choy, J. S., and S. J. Kron. 2002. NuA4 subunit Yng2 function in intra-S-phase DNA damage response. Mol. Cell. Biol. 22:8215–8225.
  • Downs, J. A., S. Allard, O. Jobin-Robitaille, A. Javaheri, A. Auger, N. Bouchard, S. J. Kron, S. P. Jackson, and J. Cote. 2004. Binding of chromatin-modifying activities to phosphorylated histone H2A at DNA damage sites. Mol. Cell 16:979–990.
  • Downs, J. A., N. F. Lowndes, and S. P. Jackson. 2000. A role for Saccharomyces cerevisiae histone H2A in DNA repair. Nature 408:1001–1004.
  • Fisher-Adams, G., and M. Grunstein. 1995. Yeast histone H4 and H3 N-termini have different effects on the chromatin structure of the GAL1 promoter. EMBO J. 14:1468–1477.
  • Freiman, R. N., and R. Tjian. 2003. Regulating the regulators: lysine modifications make their mark. Cell 112:11–17.
  • Giannattasio, M., F. Lazzaro, P. Plevani, and M. Muzi-Falconi. 2005. The DNA damage checkpoint response requires histone H2B ubiquitination by Rad6-Bre1 and H3 methylation by Dot1. J. Biol. Chem. 280:9879–9886.
  • Haber, J. E. 2000. Lucky breaks: analysis of recombination in Saccharomyces. Mutat. Res. 451:53–69.
  • Hasan, S., and M. O. Hottiger. 2002. Histone acetyl transferases: a role in DNA repair and DNA replication. J. Mol. Med. 80:463–474.
  • Hoppe, G. J., J. C. Tanny, A. D. Rudner, S. A. Gerber, S. Danaie, S. P. Gygi, and D. Moazed. 2002. Steps in assembly of silent chromatin in yeast: Sir3-independent binding of a Sir2/Sir4 complex to silencers and role for Sir2-dependent deacetylation. Mol. Cell. Biol. 22:4167–4180.
  • Huyen, Y., O. Zgheib, R. A. Ditullio, Jr., V. G. Gorgoulis, P. Zacharatos, T. J. Petty, E. A. Sheston, H. S. Mellert, E. S. Stavridi, and T. D. Halazonetis. 2004. Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks. Nature 432:406–411.
  • Iizuka, M., and M. M. Smith. 2003. Functional consequences of histone modifications. Curr. Opin. Genet. Dev. 13:154–160.
  • Jacobson, S. J., P. M. Laurenson, and L. Pillus. 2004. Functional analyses of chromatin modifications in yeast. Methods Enzymol. 377:3–55.
  • Jazayeri, A., A. D. McAinsh, and S. P. Jackson. 2004. Saccharomyces cerevisiae Sin3p facilitates DNA double-strand break repair. Proc. Natl. Acad. Sci. USA 101:1644–1649.
  • Kornberg, R. D., and J. O. Thomas. 1974. Chromatin structure: oligomers of the histones. Science 184:865–868.
  • Kuo, M. H., and C. D. Allis. 1999. In vivo cross-linking and immunoprecipitation for studying dynamic protein:DNA associations in a chromatin environment. Methods 19:425–433.
  • Lee, S. E., F. Paques, J. Sylvan, and J. E. Haber. 1999. Role of yeast SIR genes and mating type in directing DNA double-strand breaks to homologous and non-homologous repair paths. Curr. Biol. 9:767–770.
  • Lee, S. E., A. Pellicioli, M. B. Vaze, N. Sugawara, A. Malkova, M. Foiani, and J. E. Haber. 2003. Yeast Rad52 and Rad51 recombination proteins define a second pathway of DNA damage assessment in response to a single double-strand break. Mol. Cell. Biol. 23:8913–8923.
  • Lenfant, F., R. K. Mann, B. Thomsen, X. Ling, and M. Grunstein. 1996. All four core histone N-termini contain sequences required for the repression of basal transcription in yeast. EMBO J. 15:3974–3985.
  • Lisby, M., J. H. Barlow, R. C. Burgess, and R. Rothstein. 2004. Choreography of the DNA damage response: spatiotemporal relationships among checkpoint and repair proteins. Cell 118:699–713.
  • Luger, K., T. J. Rechsteiner, and T. J. Richmond. 1999. Expression and purification of recombinant histones and nucleosome reconstitution. Methods Mol. Biol. 119:1–16.
  • Malone, R. E., and R. E. Esposito. 1980. The RAD52 gene is required for homothallic interconversion of mating types and spontaneous mitotic recombination in yeast. Proc. Natl. Acad. Sci. USA 77:503–507.
  • Mann, R. K., and M. Grunstein. 1992. Histone H3 N-terminal mutations allow hyperactivation of the yeast GAL1 gene in vivo. EMBO J. 11:3297–3306.
  • Martin, S. G., T. Laroche, N. Suka, M. Grunstein, and S. M. Gasser. 1999. Relocalization of telomeric Ku and SIR proteins in response to DNA strand breaks in yeast. Cell 97:621–633.
  • McGill, C., B. Shafer, and J. Strathern. 1989. Coconversion of flanking sequences with homothallic switching. Cell 57:459–467.
  • Megee, P. C., B. A. Morgan, and M. M. Smith. 1995. Histone H4 and the maintenance of genome integrity. Genes Dev. 9:1716–1727.
  • Mills, K. D., D. A. Sinclair, and L. Guarente. 1999. MEC1-dependent redistribution of the Sir3 silencing protein from telomeres to DNA double-strand breaks. Cell 97:609–620.
  • Morrison, A. J., J. Highland, N. J. Krogan, A. Arbel-Eden, J. F. Greenblatt, J. E. Haber, and X. Shen. 2004. INO80 and gamma-H2AX interaction links ATP-dependent chromatin remodeling to DNA damage repair. Cell 119:767–775.
  • Paull, T. T., E. P. Rogakou, V. Yamazaki, C. U. Kirchgessner, M. Gellert, and W. M. Bonner. 2000. A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage. Curr. Biol. 10:886–895.
  • Pothof, J., G. van Haaften, K. Thijssen, R. S. Kamath, A. G. Fraser, J. Ahringer, R. H. Plasterk, and M. Tijsterman. 2003. Identification of genes that protect the C. elegans genome against mutations by genome-wide RNAi. Genes Dev. 17:443–448.
  • Qin, S., and M. R. Parthun. 2002. Histone H3 and the histone acetyltransferase Hat1p contribute to DNA double-strand break repair. Mol. Cell. Biol. 22:8353–8365.
  • Raveh, D., S. H. Hughes, B. K. Shafer, and J. N. Strathern. 1989. Analysis of the HO-cleaved MAT DNA intermediate generated during the mating type switch in the yeast Saccharomyces cerevisiae. Mol. Gen. Genet. 220:33–42.
  • Robert, F., D. K. Pokholok, N. M. Hannett, N. J. Rinaldi, M. Chandy, A. Rolfe, J. L. Workman, D. K. Gifford, and R. A. Young. 2004. Global position and recruitment of HATs and HDACs in the yeast genome. Mol. Cell 16:199–209.
  • Robyr, D., Y. Suka, I. Xenarios, S. K. Kurdistani, A. Wang, N. Suka, and M. Grunstein. 2002. Microarray deacetylation maps determine genome-wide functions for yeast histone deacetylases. Cell 109:437–446.
  • Rusche, L. N., and J. Rine. 2001. Conversion of a gene-specific repressor to a regional silencer. Genes Dev. 15:955–967.
  • Sanders, S. L., M. Portoso, J. Mata, J. Bahler, R. C. Allshire, and T. Kouzarides. 2004. Methylation of histone H4 lysine 20 controls recruitment of Crb2 to sites of DNA damage. Cell 119:603–614.
  • Shroff, R., A. Arbel-Eden, D. Pilch, G. Ira, W. M. Bonner, J. H. Petrini, J. E. Haber, and M. Lichten. 2004. Distribution and dynamics of chromatin modification induced by a defined DNA double-strand break. Curr. Biol. 14:1703–1711.
  • Strahl, B. D., and C. D. Allis. 2000. The language of covalent histone modifications. Nature 403:41–45.
  • Sugawara, N., X. Wang, and J. E. Haber. 2003. In vivo roles of Rad52, Rad54, and Rad55 proteins in Rad51-mediated recombination. Mol. Cell 12:209–219.
  • Suka, N., Y. Suka, A. A. Carmen, J. Wu, and M. Grunstein. 2001. Highly specific antibodies determine histone acetylation site usage in yeast heterochromatin and euchromatin. Mol. Cell 8:473–479.
  • Sung, P., K. M. Trujillo, and S. Van Komen. 2000. Recombination factors of Saccharomyces cerevisiae. Mutat. Res. 451:257–275.
  • van Attikum, H., O. Fritsch, B. Hohn, and S. M. Gasser. 2004. Recruitment of the INO80 complex by H2A phosphorylation links ATP-dependent chromatin remodeling with DNA double-strand break repair. Cell 119:777–788.
  • Wan, J. S., R. K. Mann, and M. Grunstein. 1995. Yeast histone H3 and H4 N termini function through different GAL1 regulatory elements to repress and activate transcription. Proc. Natl. Acad. Sci. USA 92:5664–5668.
  • Wu, X., J. K. Moore, and J. E. Haber. 1996. Mechanism of MATα donor preference during mating-type switching of Saccharomyces cerevisiae. Mol. Cell. Biol. 16:657–668.

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