44
Views
62
CrossRef citations to date
0
Altmetric
Gene Expression

Components of the ESCRT Pathway, DFG16, and YGR122w Are Required for Rim101 To Act as a Corepressor with Nrg1 at the Negative Regulatory Element of the DIT1 Gene of Saccharomyces cerevisiae

, , , , &
Pages 6772-6788 | Received 21 Dec 2004, Accepted 04 May 2005, Published online: 27 Mar 2023

REFERENCES

  • Amerik, A. Y., J. Nowak, S. Swaminathan, and M. Hochstrasser. 2000. The Doa4 deubiquitinating enzyme is functionally linked to the vacuolar protein-sorting and endocytic pathways. Mol. Biol. Cell 11:3365–3380.
  • Arst, H. N., and M. A. Penalva. 2003. pH regulation in Aspergillus and parallels with higher eukaryotic regulatory systems. Trends Genet. 19:224–231.
  • Babst, M., D. J. Katzmann, E. J. Estepa-Sabal, T. Meerloo, and S. D. Emr. 2002. ESCRT-III: an endosome-associated heterooligomeric protein complex required for MVB sorting. Dev. Cell 3:271–282.
  • Babst, M., D. J. Katzmann, W. B. Snyder, B. Wendland, and S. D. Emr. 2002. Endosome-associated complex, ESCRT-II, recruits transport machinery for protein sorting at the multivesicular body. Dev. Cell 3:283–289.
  • Babst, M., B. Wendland, E. J. Estepa, and S. D. Emr. 1998. The Vps4p AAA ATPase regulates membrane association of a Vps protein complex required for normal endosome function. EMBO J. 17:2982–2993.
  • Bartel, P., C. T. Chien, R. Sternglanz, and S. Fields. 1993. Elimination of false positives that arise in using the two-hybrid system. BioTechniques 14:920–924.
  • Berkey, C. D., V. K. Vyas, and M. Carlson. 2004. Nrg1 and Nrg2 transcriptional repressors are differently regulated in response to carbon source. Eukaryot. Cell 3:311–317.
  • Bilodeau, P. S., J. L. Urbanowski, S. C. Winistorfer, and R. C. Piper. 2002. The Vps27p Hse1p complex binds ubiquitin and mediates endosomal protein sorting. Nat. Cell Biol. 4:534–539.
  • Bilodeau, P. S., S. C. Winistorfer, W. R. Kearney, A. D. Robertson, and R. C. Piper. 2003. Vps27-Hse1 and ESCRT-I complexes cooperate to increase efficiency of sorting ubiquitinated proteins at the endosome. J. Cell Biol. 163:237–243.
  • Boeke, J. D., F. LaCroute, and G. R. Fink. 1984. A positive selection for mutants lacking orotidine-5′-phosphate decarboxylase activity in yeast: 5-fluoro-orotic acid resistance. Mol. Gen. Genet. 197:345–346.
  • Bogengruber, E., T. Eichberger, P. Briza, I. W. Dawes, M. Breitenbach, and R. Schricker. 1998. Sporulation-specific expression of the yeast DIT1/DIT2 promoter is controlled by a newly identified repressor element and the short form of Rim101p. Eur. J. Biochem. 258:430–436.
  • Bowers, K., J. Lottridge, S. B. Helliwell, L. M. Goldthwaite, J. P. Luzio, and T. H. Stevens. 2004. Protein-protein interactions of ESCRT complexes in the yeast Saccharomyces cerevisiae. Traffic 5:194–210.
  • Bradford, M. M. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:248–254.
  • Braun, B. R., D. Kadosh, and A. D. Johnson. 2001. NRG1, a repressor of filamentous growth in C. albicans, is down-regulated during filament induction. EMBO J. 20:4753–4761.
  • Briza, P., M. Breitenbach, A. Ellinger, and J. Segall. 1990. Isolation of two developmentally regulated genes involved in spore wall maturation in Saccharomyces cerevisiae. Genes Dev. 4:1775–1789.
  • Casadaban, M. J., A. Martinez-Arias, S. K. Shapira, and J. Chou. 1983. Beta-galactosidase gene fusions for analyzing gene expression in Escherichia coli and yeast. Methods Enzymol. 100:293–308.
  • Causton, H. C., B. Ren, S. S. Koh, C. T. Harbison, E. Kanin, E. G. Jennings, T. I. Lee, H. L. True, E. S. Lander, and R. A. Young. 2001. Remodeling of yeast genome expression in response to environmental changes. Mol. Biol. Cell 12:323–337.
  • Chu, S., J. DeRisi, M. Eisen, J. Mulholland, D. Botstein, P. O. Brown, and I. Herskowitz. 1998. The transcriptional program of sporulation in budding yeast. Science 282:699–705.
  • Clague, M. J., and S. Urbe. 2003. Hrs function: viruses provide the clue. Trends Cell Biol. 13:603–606.
  • de Nadal, E., L. Casadome, and F. Posas. 2003. Targeting the MEF2-like transcription factor Smp1 by the stress-activated Hog1 mitogen-activated protein kinase. Mol. Cell. Biol. 23:229–237.
  • Diez, E., J. Alvaro, E. A. Espeso, L. Rainbow, T. Suarez, J. Tilburn, H. N. Arst, Jr., and M. A. Penalva. 2002. Activation of the Aspergillus PacC zinc finger transcription factor requires two proteolytic steps. EMBO J. 21:1350–1359.
  • Dupre, S., and R. Haguenauer-Tsapis. 2001. Deubiquitination step in the endocytic pathway of yeast plasma membrane proteins: crucial role of Doa4p ubiquitin isopeptidase. Mol. Cell. Biol. 21:4482–4494.
  • Eguez, L., Y. S. Chung, A. Kuchibhatla, M. Paidhungat, and S. Garrett. 2004. Yeast Mn2+ transporter, Smf1p, is regulated by ubiquitin-dependent vacuolar protein sorting. Genetics 167:107–117.
  • Eisendle, M., H. Oberegger, R. Buttinger, P. Illmer, and H. Haas. 2004. Biosynthesis and uptake of siderophores is controlled by the PacC-mediated ambient-pH regulatory system in Aspergillus nidulans. Eukaryot. Cell 3:561–563.
  • Espeso, E. A., J. Tilburn, L. Sanchez-Pulido, C. V. Brown, A. Valencia, H. N. Arst, Jr., and M. A. Penalva. 1997. Specific DNA recognition by the Aspergillus nidulans three zinc finger transcription factor PacC. J. Mol. Biol. 274:466–480.
  • Fragiadakis, G. S., D. Tzamarias, and D. Alexandraki. 2004. Nhp6 facilitates Aft1 binding and Ssn6 recruitment, both essential for FRE2 transcriptional activation. EMBO J. 23:333–342.
  • Friesen, H., S. R. Hepworth, and J. Segall. 1997. An Ssn6-Tup1-dependent negative regulatory element controls sporulation-specific expression of DIT1 and DIT2 in Saccharomyces cerevisiae. Mol. Cell. Biol. 17:123–134.
  • Friesen, H., J. C. Tanny, and J. Segall. 1998. SPE3, which encodes spermidine synthase, is required for full repression through NREDIT in Saccharomyces cerevisiae. Genetics 150:59–73.
  • Futai, E., T. Maeda, H. Sorimachi, K. Kitamoto, S. Ishiura, and K. Suzuki. 1999. The protease activity of a calpain-like cysteine protease in Saccharomyces cerevisiae is required for alkaline adaptation and sporulation. Mol. Gen. Genet. 260:559–568.
  • Gaisne, M., A. M. Becam, J. Verdiere, and C. J. Herbert. 1999. A ‘natural’ mutation in Saccharomyces cerevisiae strains derived from S288c affects the complex regulatory gene HAP1 (CYP1). Curr. Genet. 36:195–200.
  • Gerrard, S. R., B. P. Levi, and T. H. Stevens. 2000. Pep12p is a multifunctional yeast syntaxin that controls entry of biosynthetic, endocytic and retrograde traffic into the prevacuolar compartment. Traffic 1:259–269.
  • Giaever, G., A. M. Chu, L. Ni, C. Connelly, L. Riles, S. Veronneau, S. Dow, A. Lucau-Danila, K. Anderson, B. Andre, A. P. Arkin, A. Astromoff, M. El-Bakkoury, R. Bangham, R. Benito, S. Brachat, S. Campanaro, M. Curtiss, K. Davis, A. Deutschbauer, K. D. Entian, P. Flaherty, F. Foury, D. J. Garfinkel, M. Gerstein, D. Gotte, U. Guldener, J. H. Hegemann, S. Hempel, Z. Herman, D. F. Jaramillo, D. E. Kelly, S. L. Kelly, P. Kotter, D. LaBonte, D. C. Lamb, N. Lan, H. Liang, H. Liao, L. Liu, C. Luo, M. Lussier, R. Mao, P. Menard, S. L. Ooi, J. L. Revuelta, C. J. Roberts, M. Rose, P. Ross-Macdonald, B. Scherens, G. Schimmack, B. Shafer, D. D. Shoemaker, S. Sookhai-Mahadeo, R. K. Storms, J. N. Strathern, G. Valle, M. Voet, G. Volckaert, C. Y. Wang, T. R. Ward, J. Wilhelmy, E. A. Winzeler, Y. Yang, G. Yen, E. Youngman, K. Yu, H. Bussey, J. D. Boeke, M. Snyder, P. Philippsen, R. W. Davis, and M. Johnston. 2002. Functional profiling of the Saccharomyces cerevisiae genome. Nature 418:387–391.
  • Gietz, D., A. St. Jean, R. A. Woods, and R. H. Schiestl. 1992. Improved method for high efficiency transformation of intact yeast cells. Nucleic Acids Res. 20:1425.
  • Goldstein, A. L., and J. H. McCusker. 1999. Three new dominant drug resistance cassettes for gene disruption in Saccharomyces cerevisiae. Yeast 15:1541–1553.
  • Green, S. R., and A. D. Johnson. 2004. Promoter-dependent roles for the Srb10 cyclin-dependent kinase and the Hda1 deacetylase in Tup1-mediated repression in Saccharomyces cerevisiae. Mol. Biol. Cell 15:4191–4202.
  • Gruenberg, J., and H. Stenmark. 2004. The biogenesis of multivesicular endosomes. Nat. Rev. Mol. Cell Biol. 5:317–323.
  • Guarente, L. 1983. Yeast promoters and lacZ fusions designed to study expression of cloned genes in yeast. Methods Enzymol. 101:181–191.
  • Haro, R., B. Garciadeblas, and A. Rodriguez-Navarro. 1991. A novel P-type ATPase from yeast involved in sodium transport. FEBS Lett. 291:189–191.
  • Hepworth, S. R., L. K. Ebisuzaki, and J. Segall. 1995. A 15-base-pair element activates the SPS4 gene midway through sporulation in Saccharomyces cerevisiae. Mol. Cell. Biol. 15:3934–3944.
  • Honigberg, S. M., and K. Purnapatre. 2003. Signal pathway integration in the switch from the mitotic cell cycle to meiosis in yeast. J. Cell Sci. 116:2137–2147.
  • Howard, J. P., J. L. Hutton, J. M. Olson, and G. S. Payne. 2002. Sla1p serves as the targeting signal recognition factor for NPFX(1,2)D-mediated endocytosis. J. Cell Biol. 157:315–326.
  • Ito, T., K. Tashiro, S. Muta, R. Ozawa, T. Chiba, M. Nishizawa, K. Yamamoto, S. Kuhara, and Y. Sakaki. 2000. Toward a protein-protein interaction map of the budding yeast: a comprehensive system to examine two-hybrid interactions in all possible combinations between the yeast proteins. Proc. Natl. Acad. Sci. USA 97:1143–1147.
  • Kassir, Y., N. Adir, E. Boger-Nadjar, N. G. Raviv, I. Rubin-Bejerano, S. Sagee, and G. Shenhar. 2003. Transcriptional regulation of meiosis in budding yeast. Int. Rev. Cytol. 224:111–171.
  • Katzmann, D. J., G. Odorizzi, and S. D. Emr. 2002. Receptor downregulation and multivesicular-body sorting. Nat. Rev. Mol. Cell Biol. 3:893–905.
  • Katzmann, D. J., C. J. Stefan, M. Babst, and S. D. Emr. 2003. Vps27 recruits ESCRT machinery to endosomes during MVB sorting. J. Cell Biol. 162:413–423.
  • Kranz, A., A. Kinner, and R. Kolling. 2001. A family of small coiled-coil-forming proteins functioning at the late endosome in yeast. Mol. Biol. Cell 12:711–723.
  • Kuchin, S., V. K. Vyas, and M. Carlson. 2002. Snf1 protein kinase and the repressors Nrg1 and Nrg2 regulate FLO11, haploid invasive growth, and diploid pseudohyphal differentiation. Mol. Cell. Biol. 22:3994–4000.
  • Kupiec, M., B. Byers, R. E. Esposito, and A. P. Mitchell. 1997. Meiosis and sporulation in Saccharomyces cerevisiae, p. 899–1036. In J. R. Pringle, J. R. Broach, and E. W. Jones (ed.), The molecular biology of the yeast Saccharomyces: cell cycle and cell biology, vol. 3. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
  • Labbe, S., Z. Zhu, and D. J. Thiele. 1997. Copper-specific transcriptional repression of yeast genes encoding critical components in the copper transport pathway. J. Biol. Chem. 272:15951–15958.
  • Lamb, T. M., and A. P. Mitchell. 2003. The transcription factor Rim101p governs ion tolerance and cell differentiation by direct repression of the regulatory genes NRG1 and SMP1 in Saccharomyces cerevisiae. Mol. Cell. Biol. 23:677–686.
  • Lamb, T. M., W. Xu, A. Diamond, and A. P. Mitchell. 2001. Alkaline response genes of Saccharomyces cerevisiae and their relationship to the RIM101 pathway. J. Biol. Chem. 276:1850–1856.
  • Li, W., and A. P. Mitchell. 1997. Proteolytic activation of Rim1p, a positive regulator of yeast sporulation and invasive growth. Genetics 145:63–73.
  • Longtine, M. S., A. McKenzie III, D. J. Demarini, N. G. Shah, A. Wach, A. Brachat, P. Philippsen, and J. R. Pringle. 1998. Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae. Yeast 14:953–961.
  • Losko, S., F. Kopp, A. Kranz, and R. Kolling. 2001. Uptake of the ATP-binding cassette (ABC) transporter Ste6 into the yeast vacuole is blocked in the doa4 mutant. Mol. Biol. Cell 12:1047–1059.
  • Luhtala, N., and G. Odorizzi. 2004. Bro1 coordinates deubiquitination in the multivesicular body pathway by recruiting Doa4 to endosomes. J. Cell Biol. 166:717–729.
  • Lussier, M., A. M. White, J. Sheraton, T. di Paolo, J. Treadwell, S. B. Southard, C. I. Horenstein, J. Chen-Weiner, A. F. Ram, J. C. Kapteyn, T. W. Roemer, D. H. Vo, D. C. Bondoc, J. Hall, W. W. Zhong, A. M. Sdicu, J. Davies, F. M. Klis, P. W. Robbins, and H. Bussey. 1997. Large scale identification of genes involved in cell surface biosynthesis and architecture in Saccharomyces cerevisiae. Genetics 147:435–450.
  • McCord, R., M. Pierce, J. Xie, S. Wonkatal, C. Mickel, and A. K. Vershon. 2003. Rfm1, a novel tethering factor required to recruit the Hst1 histone deacetylase for repression of middle sporulation genes. Mol. Cell. Biol. 23:2009–2016.
  • Mendizabal, I., A. Pascual-Ahuir, R. Serrano, and I. F. de Larrinoa. 2001. Promoter sequences regulated by the calcineurin-activated transcription factor Crz1 in the yeast ENA1 gene. Mol. Genet. Genomics 265:801–811.
  • Mosch, H. U., and G. R. Fink. 1997. Dissection of filamentous growth by transposon mutagenesis in Saccharomyces cerevisiae. Genetics 145:671–684.
  • Murad, A. M., P. Leng, M. Straffon, J. Wishart, S. Macaskill, D. MacCallum, N. Schnell, D. Talibi, D. Marechal, F. Tekaia, C. d'Enfert, C. Gaillardin, F. C. Odds, and A. J. Brown. 2001. NRG1 represses yeast-hypha morphogenesis and hypha-specific gene expression in Candida albicans. EMBO J. 20:4742–4752.
  • Nikko, E., A. M. Marini, and B. Andre. 2003. Permease recycling and ubiquitination status reveal a particular role for Bro1 in the multivesicular body pathway. J. Biol. Chem. 278:50732–50743.
  • Odorizzi, G., D. J. Katzmann, M. Babst, A. Audhya, and S. D. Emr. 2003. Bro1 is an endosome-associated protein that functions in the MVB pathway in Saccharomyces cerevisiae. J. Cell Sci. 116:1893–1903.
  • Palecek, S. P., A. S. Parikh, and S. J. Kron. 2002. Sensing, signalling and integrating physical processes during Saccharomyces cerevisiae invasive and filamentous growth. Microbiology 148:893–907.
  • Park, S. H., S. S. Koh, J. H. Chun, H. J. Hwang, and H. S. Kang. 1999. Nrg1 is a transcriptional repressor for glucose repression of STA1 gene expression in Saccharomyces cerevisiae. Mol. Cell. Biol. 19:2044–2050.
  • Penalva, M. A., and H. N. Arst, Jr. 2004. Recent advances in the characterization of ambient pH regulation of gene expression in filamentous fungi and yeasts. Annu. Rev. Microbiol. 58:425–451.
  • Penalva, M. A., and H. N. Arst, Jr. 2002. Regulation of gene expression by ambient pH in filamentous fungi and yeasts. Microbiol. Mol. Biol. Rev. 66:426–446.
  • Pornillos, O., J. E. Garrus, and W. I. Sundquist. 2002. Mechanisms of enveloped RNA virus budding. Trends Cell Biol. 12:569–579.
  • Primig, M., R. M. Williams, E. A. Winzeler, G. G. Tevzadze, A. R. Conway, S. Y. Hwang, R. W. Davis, and R. E. Esposito. 2000. The core meiotic transcriptome in budding yeasts. Nat. Genet. 26:415–423.
  • Proft, M., and K. Struhl. 2002. Hog1 kinase converts the Sko1-Cyc8-Tup1 repressor complex into an activator that recruits SAGA and SWI/SNF in response to osmotic stress. Mol. Cell 9:1307–1317.
  • Raiborg, C., T. E. Rusten, and H. Stenmark. 2003. Protein sorting into multivesicular endosomes. Curr. Opin. Cell Biol. 15:446–455.
  • Rose, M. D., and J. R. Broach. 1991. Cloning genes by complementation in yeast. Methods Enzymol. 194:195–230.
  • Rowland, O., and J. Segall. 1998. A hydrophobic segment within the 81-amino-acid domain of TFIIIA from Saccharomyces cerevisiae is essential for its transcription factor activity. Mol. Cell. Biol. 18:420–432.
  • Rowland, O., and J. Segall. 1996. Interaction of wild-type and truncated forms of transcription factor IIIA from Saccharomyces cerevisiae with the 5 S RNA gene. J. Biol. Chem. 271:12103–12110.
  • Serrano, R., D. Bernal, E. Simon, and J. Arino. 2004. Copper and iron are the limiting factors for growth of the yeast Saccharomyces cerevisiae in an alkaline environment. J. Biol. Chem. 279:19698–19704.
  • Serrano, R., A. Ruiz, D. Bernal, J. R. Chambers, and J. Arino. 2002. The transcriptional response to alkaline pH in Saccharomyces cerevisiae: evidence for calcium-mediated signalling. Mol. Microbiol. 46:1319–1333.
  • Sherman, F. 1991. Getting started with yeast. Methods Enzymol. 194:3–21.
  • Simonsen, A., A. E. Wurmser, S. D. Emr, and H. Stenmark. 2001. The role of phosphoinositides in membrane transport. Curr. Opin. Cell Biol. 13:485–492.
  • Smith, R. L., and A. D. Johnson. 2000. Turning genes off by Ssn6-Tup1: a conserved system of transcriptional repression in eukaryotes. Trends Biochem. Sci. 25:325–330.
  • Su, S. S., and A. P. Mitchell. 1993. Identification of functionally related genes that stimulate early meiotic gene expression in yeast. Genetics 133:67–77.
  • Su, S. S., and A. P. Mitchell. 1993. Molecular characterization of the yeast meiotic regulatory gene RIM1. Nucleic Acids Res. 21:3789–3797.
  • Swaminathan, S., A. Y. Amerik, and M. Hochstrasser. 1999. The Doa4 deubiquitinating enzyme is required for ubiquitin homeostasis in yeast. Mol. Biol. Cell 10:2583–2594.
  • Tang, H. Y., A. Munn, and M. Cai. 1997. EH domain proteins Pan1p and End3p are components of a complex that plays a dual role in organization of the cortical actin cytoskeleton and endocytosis in Saccharomyces cerevisiae. Mol. Cell. Biol. 17:4294–4304.
  • Tilburn, J., S. Sarkar, D. A. Widdick, E. A. Espeso, M. Orejas, J. Mungroo, M. A. Penalva, and H. N. Arst, Jr. 1995. The Aspergillus PacC zinc finger transcription factor mediates regulation of both acid- and alkaline-expressed genes by ambient pH. EMBO J. 14:779–790.
  • Tong, A. H., M. Evangelista, A. B. Parsons, H. Xu, G. D. Bader, N. Page, M. Robinson, S. Raghibizadeh, C. W. Hogue, H. Bussey, B. Andrews, M. Tyers, and C. Boone. 2001. Systematic genetic analysis with ordered arrays of yeast deletion mutants. Science 294:2364–2368.
  • Treton, B., S. Blanchin-Roland, M. Lambert, A. Lepingle, and C. Gaillardin. 2000. Ambient pH signalling in ascomycetous yeasts involves homologues of the Aspergillus nidulans genes palF and paIH. Mol. Gen. Genet. 263:505–513.
  • Tu, J., L. G. Vallier, and M. Carlson. 1993. Molecular and genetic analysis of the SNF7 gene in Saccharomyces cerevisiae. Genetics 135:17–23.
  • Uetz, P., L. Giot, G. Cagney, T. A. Mansfield, R. S. Judson, J. R. Knight, D. Lockshon, V. Narayan, M. Srinivasan, P. Pochart, A. Qureshi-Emili, Y. Li, B. Godwin, D. Conover, T. Kalbfleisch, G. Vijayadamodar, M. Yang, M. Johnston, S. Fields, and J. M. Rothberg. 2000. A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae. Nature 403:623–627.
  • Vallier, L. G., and M. Carlson. 1991. New SNF genes, GAL11 and GRR1 affect SUC2 expression in Saccharomyces cerevisiae. Genetics 129:675–684.
  • Van Den Hazel, H. B., M. C. Kielland-Brandt, and J. R. Winther. 1996. Review: biosynthesis and function of yeast vacuolar proteases. Yeast 12:1–16.
  • Viladevall, L., R. Serrano, A. Ruiz, G. Domenech, J. Giraldo, A. Barcelo, and J. Arino. 2004. Characterization of the calcium-mediated response to alkaline stress in Saccharomyces cerevisiae. J. Biol. Chem. 279:43614–43624.
  • von Schwedler, U. K., M. Stuchell, B. Muller, D. M. Ward, H. Y. Chung, E. Morita, H. E. Wang, T. Davis, G. P. He, D. M. Cimbora, A. Scott, H. G. Krausslich, J. Kaplan, S. G. Morham, and W. I. Sundquist. 2003. The protein network of HIV budding. Cell 114:701–713.
  • Vyas, V. K., S. Kuchin, and M. Carlson. 2001. Interaction of the repressors Nrg1 and Nrg2 with the Snf1 protein kinase in Saccharomyces cerevisiae. Genetics 158:563–572.
  • Williams, F. E., and R. J. Trumbly. 1990. Characterization of TUP1, a mediator of glucose repression in Saccharomyces cerevisiae. Mol. Cell. Biol. 10:6500–6511.
  • Wolfe, S. A., R. A. Grant, and C. O. Pabo. 2003. Structure of a designed dimeric zinc finger protein bound to DNA. Biochemistry 42:13401–13409.
  • Xie, J., M. Pierce, V. Gailus-Durner, M. Wagner, E. Winter, and A. K. Vershon. 1999. Sum1 and Hst1 repress middle sporulation-specific gene expression during mitosis in Saccharomyces cerevisiae. EMBO J. 18:6448–6454.
  • Xu, W., and A. P. Mitchell. 2001. Yeast PalA/AIP1/Alix homolog Rim20p associates with a PEST-like region and is required for its proteolytic cleavage. J. Bacteriol. 183:6917–6923.
  • Xu, W., F. J. Smith, Jr., R. Subaran, and A. P. Mitchell. 2004. Multivesicular body-ESCRT components function in pH response regulation in Saccharomyces cerevisiae and Candida albicans. Mol. Biol. Cell 15:5528–5537.
  • Yamaguchi-Iwai, Y., R. Stearman, A. Dancis, and R. D. Klausner. 1996. Iron-regulated DNA binding by the AFT1 protein controls the iron regulon in yeast. EMBO J. 15:3377–3384.
  • Zhang, Z., and J. C. Reese. 2004. Redundant mechanisms are used by Ssn6-Tup1 in repressing chromosomal gene transcription in Saccharomyces cerevisiae. J. Biol. Chem. 279:39240–39250.
  • Zhou, H., and F. Winston. 2001. NRG1 is required for glucose repression of the SUC2 and GAL genes of Saccharomyces cerevisiae. BMC Genet. 2:5.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.