REFERENCES
- Campbell, R. E., O. Tour, A. E. Palmer, P. A. Steinbach, G. S. Baird, D. A. Zacharias, and R. Y. Tsien. 2002. A monomeric red fluorescent protein. Proc. Natl. Acad. Sci. USA 99:7877–7882.
- Cheeseman, I. M., S. Niessen, S. Anderson, F. Hyndman, J. R. Yates III, K. Oegema, and A. Desai. 2004. A conserved protein network controls assembly of the outer kinetochore and its ability to sustain tension. Genes Dev. 18:2255–2268.
- Choo, K. H. 2001. Domain organization at centromere and neocentromere. Dev. Cell 1:165–177.
- Cleveland, D. W., Y. Mao, and K. F. Sullivan. 2003. Centromeres and kinetochores: from epigenetics to mitotic checkpoint signaling. Cell 112:407–421.
- Craig, J. M., W. C. Earnshaw, and P. Vagnarelli. 1999. Mammalian centromeres: DNA sequence, protein composition, and role in cell cycle progression. Exp. Cell Res. 246:249–262.
- Dundr, M., U. Hoffmann-Rohrer, Q. Hu, I. Grummt, L. I. Rothblum, R. D. Phair, and T. Misteli. 2002. A kinetic framework for a mammalian RNA polymerase in vivo. Science 298:1623–1626.
- Dundr, M., M. D. Hebert, T. S. Karpova, D. Stanek, H. Xu, K. B. Shpargel, U. T. Meier, K. M. Neugebauer, A. G. Matera, and T. Misteli. 2004. In vivo kinetics of Cajal body components. J. Cell Biol. 164:831–842.
- Fukagawa, T., and W. R. A. Brown. 1997. Efficient conditional mutation of the vertebrate CENP-C gene. Hum. Mol. Genet. 6:2301–2308.
- Fukagawa, T., C. Pendon, J. Morris, and W. Brown. 1999. CENP-C is necessary but not sufficient to induce formation of functional centromere. EMBO J. 18:4196–4209.
- Fukagawa, T., Y. Mikami, A. Nishihashi, V. Regnier, T. Haraguchi, Y. Hiraoka, N. Sugata, K. Todokoro, W. Brown, and T. Ikemura. 2001. CENP-H, a constitutive centromere component, is required for centromere targeting of CENP-C in vertebrate cells. EMBO J. 20:4603–4617.
- Fukagawa, T. 2004. Assembly of kinetochore in vertebrate cells. Exp. Cell Res. 296:21–27.
- Fukagawa, T., M. Nogami, M. Yoshikawa, M. Ikeno, T. Okazaki, Y. Takami, T. Nakayama, and M. Oshimura. 2004. Dicer is essential for formation of the heterochromatin structure in vertebrate cells. Nat. Cell Biol. 6:784–791.
- Goshima, G., T. Kiyomitsu, K. Koda, and M. Yanagida. 2003. Human centromere chromatin protein hMis12, essential for equal segregation, is independent of CENP-A loading pathway. J. Cell Biol. 160:25–39.
- Hanissian, S. H., U. Akbar, B. Teng, Z. Janjetovic, A. Hoffmann, J. K. Hitzler, N. Iscove, K. Hamre, X. Du, Y. Tong, S. Mukatira, J. H. Robertson, and S. W. Morris. 2004. cDNA cloning and characterization of a novel gene encoding the MLF1-interacting protein MLF1IP. Oncogene 23:3700–3707.
- Haraguchi, T., T. Kaneda, and Y. Hiraoka. 1997. Dynamics of chromosomes and microtubules visualized by multiple-wavelength fluorescence imaging in living mammalian cells: effects of mitotic inhibitors on cell cycle progression. Genes Cells 2:369–380.
- Haraguchi, T., D.-Q. Ding, A. Yamamoto, T. Kaneda, T. Koujin, and Y. Hiraoka. 1999. Multiple-color fluorescence imaging of chromosomes and microtubules in living cells. Cell Struct. Funct. 24:291–298.
- Hirose, K., T. Kawashima, I. Iwamoto, T. Nosaka, and T. Kitamura. 2001. MgcRacGAP is involved in cytokinesis through associating with mitotic spindle and midbody. J. Biol. Chem. 276:5821–5828.
- Hori, T., T. Haraguchi, Y. Hiraoka, H. Kimura, and T. Fukagawa. 2003. Dynamic behavior of Nuf2-Hec1 complex that localizes to the centrosome and centromere and is essential for mitotic progression in vertebrate cells. J. Cell Sci. 116:3347–3362.
- Jantsch-Plunger, V., P. Gonczy, A. Romano, H. Schnabel, D. Hamill, R. Schnabel, A. A. Hyman, and M. Glotzer. 2000. CYK-4: a Rho family gtpase activating protein (GAP) required for central spindle formation and cytokinesis. J. Cell Biol. 149:1391–1404.
- Kalitsis, P., K. J. Fowler, E. Earle, J. Hill, and K. H. A. Choo. 1998. Targeted disruption of mouse centromere protein C gene leads to mitotic disarray and early embryo death. Proc. Natl. Acad. Sci. USA 95:576–582.
- Lengauer, C., K. W. Kinzler, and B. Vogelstein. 1998. Genetic instabilities in human cancers. Nature 396:643–649.
- Liu, S. T., J. C. Hittle, S. A. Jablonski, M. S. Campbell, K. Yoda, and T. J. Yen. 2003. Human CENP-I specifies localization of CENP-F, MAD1 and MAD2 to kinetochores and is essential for mitosis. Nat. Cell Biol. 5:341–345.
- Mellone, B. G., and R. C. Allshire. 2003. Stretching it: putting the CEN(P-A) in centromere. Curr. Opin. Cell Biol. 13:191–198.
- Mikami, Y., T. Hori, H. Kimura, and T. Fukagawa. 2005. The functional region of CENP-H interacts with the Nuf2 complex that localizes to centromere during mitosis. Mol. Cell. Biol. 25:1958–1970.
- Minoshima, Y., T. Kawashima, K. Hirose, Y. Tonozuka, A. Kawajiri, Y. C. Bao, X. Deng, M. Tatsuka, S. Narumiya, W. S. May, Jr., T. Nosaka, K. Semba, T. Inoue, T. Satoh, M. Inagaki, and T. Kitamura. 2003. Phosphorylation by aurora B converts MgcRacGAP to a RhoGAP during cytokinesis. Dev. Cell 4:549–560.
- Musacchio, A., and K. G. Hardwick. 2002. The spindle checkpoint: structural insights into dynamic signalling. Nat. Rev. Mol. Cell Biol. 3:731–741.
- Nasmyth, K. 2002. Segregating sister genomes: the molecular biology of chromosome separation. Science 297:559–565.
- Nishihashi, A., T. Haraguchi, Y. Hiraoka, T. Ikemura, V. Regnier, H. Dodson, W. C. Earnshaw, and T. Fukagawa. 2002. CENP-I is essential for centromere function in vertebrate cells. Dev. Cell 2:463–476.
- Obuse, C., H. Yang, N. Nozaki, S. Goto, T. Okazaki, and K. Yoda. 2004. Proteomics analysis of the centromere complex from HeLa interphase cells: UV-damaged DNA binding protein 1 (DDB-1) is a component of the CEN-complex, while BMI-1 is transiently co-localized with the centromeric region in interphase. Genes Cells 9:105–120.
- Obuse, C., O. Iwasaki, T. Kiyomitsu, G. Goshima, Y. Toyoda, and M. Yanagida. 2004. A conserved Mis12 centromere complex is linked to heterochromatic HP1 and outer kinetochore protein Zwint-1. Nat. Cell Biol. 6:1135–1141.
- Oceguera-Yanez, F., K. Kimura, S. Yasuda, C. Higashida, T. Kitamura, Y. Hiraoka, T. Haraguchi, and S. Narumiya. 2005. Ect2 and MgcRacGAP regulate the activation and function of Cdc42 in mitosis. J. Cell Biol. 168:221–232.
- Palmer, D. K., and R. L. Margolis. 1987. A 17-kD centromere protein (CENP-A) copurifies with nucleosome core particles and with histones. J. Cell Biol. 104:805–815.
- Pan, H.-Y., T.-J. Zhang, X.-P. Wang, J.-H. Deng, F.-C. Zhou, and S.-J. Gao. 2003. Identification of a novel cellular transcriptional repressor interacting with the latent nuclear antigen of Kaposi's sarcoma-associated herpesvirus. J. Virol. 77:9758–9768.
- Pluta, A. F., A. M. Mackay, A. M. Ainsztein, I. G. Goldberg, and W. C. Earnshaw. 1995. The centromere: hub of chromosomal activities. Science 270:1591–1594.
- Regnier, V., P. Vagnarelli, T. Fukagawa, T. Zerjal, E. Burns, D. Trouche, W. Earnshaw, and W. Brown. 2005. CENP-A is required for accurate chromosome segregation and sustained kinetochore association of BubR1. Mol. Cell. Biol. 25:3967–3981.
- Saitoh, H., J. Tomkiel, C. A. Cooke, H. Ratrie, M. Maure, N. F. Rothfield, and W. C. Earnshaw. 1992. CENP-C, an autoantigen in scleroderma, is a component of the human inner kinetochore plate. Cell 70:115–125.
- Shah, J. V., E. Botvinick, Z. Bonday, F. Furnari, M. Berns, and D. W. Cleveland. 2004. Dynamics of centromere and kinetochore proteins; implications for checkpoint signaling and silencing. Curr. Biol. 14:942–952.
- Shelby, R. D., O. Vafa, and K. F. Sullivan. 1997. Assembly of CENP-A into centromere chromatin requires a cooperative array of nucleosomal DNA contact sites. J. Cell Biol. 136:501–513.
- Sonoda, E., T. Matsusaka, C. Morrison, P. Vagnarelli, O. Hoshi, T. Ushiki, K. Nojima, T. Fukagawa, I. C. Waizenegger, J. M. Peters, W. C. Earnshaw, and S. Takeda. 2001. Scc1/Rad21/Mcd1 is required for sister chromatid cohesion and kinetochore function in vertebrate cells. Dev. Cell 1:759–770.
- Sugata, N., S. Li, W. C. Earnshaw, T. J. Yen, K. Yoda, H. Masumoto, E. Munekata, P. E. Warburton, and K. Todokoro. 2000. Human CENP-H multimers colocalize with CENP-A and CENP-C at active centromere-kinetochore complexes. Hum. Mol. Genet. 9:2919–2926.
- Sullivan, B. A., and S. Schwartz. 1995. Identification of centromeric antigens in dicentric Robertsonian translocations: CENP-C and CENP-E are necessary components of functional centromeres. Hum. Mol. Genet. 4:2189–2197.
- Tomkiel, J., C. A. Cooke, H. Saitoh, R. L. Bernat, and W. C. Earnshaw. 1994. CENP-C is required for maintaining proper kinetochore size and for a timely transition to anaphase. J. Cell Biol. 125:531–545.
- Warburton, P. E., C. A. Cooke, S. Bourassa, O. Vafa, B. A. Sullivan, G. Stetten, G. Gimelli, D. Warburton, C. Tyler-Smith, K. F. Sullivan, G. G. Poirier, and W. C. Earnshaw. 1997. Immunolocalization of CENP-A suggests a novel nucleosome structure at the inner kinetochore plate of active centromeres. Curr. Biol. 7:901–904.
- Westermann, S., I. M. Cheeseman, S. Anderson, J. R. Yates III, D. G. Drubin, and G. Barnes. 2003. Architecture of the budding yeast kinetochore reveals a conserved molecular core. J. Cell Biol. 163:215–222.
- Wigge, P. A., and J. V. Kilmartin. 2001. The Ndc80p complex from Saccharomyces cerevisiae contains conserved centromere components and has a function in chromosome segregation. J. Cell Biol. 152:349–360.