Importance of Introns in the Growth Regulation of mRNA Levels of the Proliferating Cell Nuclear Antigen Gene

Literature Cited

• Almendral, J. M., D., Huebsch, P. A., Blundell, H., MacDonald- Bravo, and R. Bravo 1987. Cloning and sequence of the human nuclear protein cyclin: homology with DNA-binding proteins. Proc. Natl. Acad. Sci. USA 84: 1575-1579.
   PubMed Web of Science ®Google Scholar
• Bornstein, P., J., McKay, J. K., Morishima, S., Devarayalu, and R. E. Gelinas 1987. Regulatory elements in the first intron contribute to transcriptional control of the human 1(1) collagen gene. Proc. Natl. Acad. Sci. USA 84: 886-8873.
   PubMedGoogle Scholar
• Bozzoni, I., P., Fragapane, F., Annesi, P., Pierandrei-Amaldi, F., Amaldi, and E. Beccari 1984. Expression of two Xenopus laevis ribosomal protein genes in injected frog oocytes. A specific splicing block interferes with the LI RNA maturation. J. Mol. Biol. 180: 987-1005.
   PubMedGoogle Scholar
• Brand, A. H., G., Micklem, and K. Nasmyth 1987. A yeast silencer contains sequences that can promote autonomous plasmid replication and transcriptional activation. Cell 51: 709-719.
   PubMedGoogle Scholar
• Bravo, R. 1986. Synthesis of the nuclear protein cyclin (PCNA) and its relationship with DNA replication. Exp. Cell Res. 163: 287-293.
   PubMed Web of Science ®Google Scholar
• Bravo, R., R., Frank, P. A., Blundell, and H. MacDonald-Bravo 1987. Cyclin/PCNA is the auxiliary protein of DNA polymerase delta. Nature (London) 326: 515-517.
   PubMed Web of Science ®Google Scholar
• Bravo, R., and H. MacDonald-Bravo 1985. Changes in the nuclear distribution of cyclin (PCNA) but not its synthesis depend on DNA replication. EMBO J. 4: 655-661.
   PubMed Web of Science ®Google Scholar
• Buchman, A. R., and P. Berg 1988. Comparison of intron- dependent and intron-independent gene expression. Mol. Cell. Biol. 8: 4395-4405.
   PubMed Web of Science ®Google Scholar
• Callis, J., M., Fromm, and V. Walbot 1987. Introns increase gene expression in cultured maize cells. Genes Dev. 1: 1183-1200.
   PubMed Web of Science ®Google Scholar
• Chomczynski, P., and N. Sacchi 1987. Single-step method of RNA isolation by acid guanidium thiocyanate-phenol-chloro- form extraction. Anal. Biochem. 162: 156-159.
   PubMed Web of Science ®Google Scholar
• Chung, S., and R. P. Perry 1989. Importance of introns for expression of mouse ribosomal protein gene rpL32. Mol. Cell. Biol. 9: 2075-2082.
   PubMedGoogle Scholar
• Coppock, D. L., and A. B. Pardee 1987. Control of thymidine kinase mRNA during the cell cycle. Mol. Cell. Biol. 7: 2925-2932.
   PubMed Web of Science ®Google Scholar
• Deng, T., Y., Li, and L. F. Johnson 1989. Thymidylate synthase gene expression is stimulated by some (but not all) introns. Nucleic Acids Res. 17: 645-658.
   PubMedGoogle Scholar
• Feinberg, A. P., and B. Vogelstein 1983. A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal. Biochem. 132: 6-13.
   PubMed Web of Science ®Google Scholar
• Gritz, L., and J. Davies 1983. Plasmid-encoded hygromycin B resistance: the sequence of hygromycin B phosphotransferase gene and its expression in Escherichia coli and Saccharomyces cerevisiae. Gene 25: 179-188.
   PubMed Web of Science ®Google Scholar
• Grass, P., and G. Khoury 1980. Rescue of splicing defective mutant by insertion of an heterologous intron. Nature (London) 286: 634-637.
   PubMedGoogle Scholar
• Hamer, D. H., and P. Leder 1979. Splicing and the formation of stable RNA. Cell 18: 1299-1302.
   PubMedGoogle Scholar
• Jaskulski, D., J. K., deRiel, W. E., Mercer, B., Calabretta, and R. Baserga 1988. Inhibition of cellular proliferation by antisense oligodeoxynucleotides to PCNA cyclin. Science 240: 1544-1546.
   PubMed Web of Science ®Google Scholar
• Jaskulski, D., G., Gatti, S., Travali, B., Calabretta, and R. Baserga 1988. Regulation of the proliferating cell nuclear anti gen cyclin and thymidine kinase mRNA levels by growth factors. J. Biol. Chem. 263: 10175-10179.
   PubMed Web of Science ®Google Scholar
• Karpinski, B. A., L. H., Yang, P., Cacheris, G. D., Morle, and J. M. Leiden 1989. The first intron of the 4F2 heavy-chain gene contains a transcriptional enhancer element that binds multiple nuclear proteins. Mol. Cell. Biol. 9: 2588-2597.
   PubMedGoogle Scholar
• Ku, D.-H., S., Travali, B., Calabretta, K., Huebner, and R. Baserga 1989. Human gene for proliferating cell nuclear antigen has pseudogenes and localizes to chromosome 20. Somatic Cell Mol. Genet. 15: 297-307.
   PubMedGoogle Scholar
• Lee, S. H., Y., Ishimi, M. K., Kenny, P., Bullock, F. B., Dean, and J. Hurwitz 1988. An inhibitor of the in vitro elongation reaction of simian virus 40 DNA replication is overcome by proliferating cell nuclear antigen. Proc. Natl. Acad. Sci. USA 85: 9469-9473.
   PubMedGoogle Scholar
• Liu, Y. C, R. L., Marraccino, P. C., Keng, R. A., Bambara, E. M., Lord, W. G., Chou, and S. B. Zain 1989. Requirement for proliferating cell nuclear antigen expression during stages of the Chinese hamster ovary cell cycle. Biochemistry 28: 2967-2974.
   PubMed Web of Science ®Google Scholar
• Loreni, F., I., Ruberti, I., Bozzoni, P., Pierandrei-Amaldi, and F. Amaldi 1985. Nucleotide sequence of the LI ribosomal protein gene of Xenopus laevis: remarkable sequence homology among introns. EMBO J. 4: 3483-3488.
   PubMed Web of Science ®Google Scholar
• Matsumoto, K., T., Moriuchi, T., Koji, and P. K. Nakane 1987. Molecular cloning of cDNA coding for rate proliferating cell nuclear antigen (PCNA)/cyclin. EMBO J. 6: 637-642.
   PubMed Web of Science ®Google Scholar
• Moore, K., K., Sullivan, E. M., Tan, and M. B. Prystowsky 1987. Proliferating cell nuclear antigen/cyclin is an interleukin-2 re sponsive gene. J. Biol. Chem. 262: 8447-8450.
   PubMedGoogle Scholar
• Munn, T. Z., and G. I. Mues 1988. Highly conserved repeats in heat-shock introns. Nature (London) 332: 789.
   PubMedGoogle Scholar
• Pellegrino, R., and B. DeCrombrugghe 1987. Identification of a cell-specific transcriptional enhancer in the first intron of the mouse alpha (type I) collagen gene. Proc. Natl. Acad. Sci. USA 84: 5590-5594.
   PubMedGoogle Scholar
• Prelich, G., M., Kostura, D. R., Marshak, M. B., Mathews, and B. Stillman 1987. The cell-cycle regulated proliferating cell nuclear antigen is required for SV40 DNA replication in vitro. Nature (London) 326: 471-475.
   PubMed Web of Science ®Google Scholar
• Prelich, G., and B. Stillman 1988. Coordinated leading and lagging strand synthesis during SV40 DNA replication in vitro requires PCNA. Cell 53: 117-126.
   PubMed Web of Science ®Google Scholar
• Prelich, G., C. K., Tan, M., Kostura, M. B., Mathews, A. G., So, K. M., Downey, and B. Stillman 1987. Functional identity of proliferating cell nuclear antigen and a DNA polymerase delta auxiliary protein. Nature (London) 326: 517-520.
   PubMed Web of Science ®Google Scholar
• Rippe, R. A., S.-I., Lorenzen, D. A., Brenner, and M. Breindl 1989. Regulatory elements in the 5′-flanking region and the first intron contribute to transcriptional control of the mouse alpha 1 type I collagen gene. Mol. Cell. Biol. 9: 2224-2227.
   PubMedGoogle Scholar
• Scher, C. D., R. C., Shephard, N. H., Antoniades, and C. D. Stiles 1979. Platelet derived growth factor and the regulation of the mammalian fibroblasts cell cycle. Biochim. Biophys. Acta 560: 217-241.
   PubMed Web of Science ®Google Scholar
• Shen, Y. M., R. R., Hirschhorn, W. E., Mercer, E., Surmacz, Y., Tsutsui, K. J., Soprano, and R. Baserga 1982. Gene transfer: DNA microinjection compared with DNA transfection with a very high efficiency. Mol. Cell. Biol. 2: 1145-1154.
   PubMedGoogle Scholar
• Shipman, P. M., D. E., Sabath, A. H., Fischer, P. G., Comber, K., Sullivan, E. M., Tan, and M. B. Prystowsky 1988. Cyclin mRNA and protein expression in recombinant interleukin-2-stimulated cloned murine T lymphocytes. J. Cell. Biochem. 38: 189-198.
   PubMed Web of Science ®Google Scholar
• Slater, E. P., O., Rabenau, M., Karin, J. D., Baster, and M. Beato 1985. Glucocorticoid receptor binding and activation of a heterologous promoter by dexamethasone by the first intron of the human growth hormone gene. Mol. Cell. Biol. 5: 2984-2992.
   PubMed Web of Science ®Google Scholar
• Stiles, C. D., G. T., Capone, C. D., Scher, N. H., Antoniades, J. J., Van Wyk, and W. J. Pledger 1979. Dual control of cell growth by somatomedins and platelet derived growth factor. Proc. Natl. Acad. Sci. USA 76: 1279-1283.
   PubMed Web of Science ®Google Scholar
• Takasaki, J., D., Fischwild, and E. M. Tan 1984. Characteriza tion of proliferating cell nuclear antigen recognized by autoanti bodies in lupus sera. J. Exp. Med. 159: 981-992.
   PubMed Web of Science ®Google Scholar
• Tan, E. M., K., Ogata, and Y. Takasaki. 1987. PCNA/cyclin: a lupus antigen connected with DNA replication. J. Rheumatol. 14 (Suppl. 13): 91-96.
   PubMedGoogle Scholar
• Thomas, P. S. 1983. Hybridization of denatured RNA trans ferred on dotted nitrocellulose paper. Methods Enzymol. 100: 255-266.
   PubMed Web of Science ®Google Scholar
• Travali, S., D.-H., Ku, M. G., Rizzo, L., Ottavio, R., Baserga, and B. Calabretta 1989. Structure of the human gene for the proliferating cell nuclear antigen. J. Biol. Chem. 264: 7466-7472.
   PubMed Web of Science ®Google Scholar
• Travali, S., K. E., Lipson, D., Jaskulski, E., Lauret, and R. Baserga 1988. Role of the promoter in the regulation of the thymidine kinase gene. Mol. Cell. Biol. 8: 1551-1557.
   PubMedGoogle Scholar
• Venolia, L., G., Urlaub, and L. A. Chasin 1987. Polyadenylation of Chinese hamster dihydrofolate reductase genomic genes and minigenes after gene transfer. Somatic Cell Mol. Genet. 13: 491-504.
   PubMedGoogle Scholar
• Wold, M. S., D. H., Weinberg, D. M., Virshup, J. J., Li, and T. J. Kelly 1989. Identification of cellular proteins required for simian virus 40 DNA replication. J. Biol. Chem. 264: 2801-2809.
   PubMedGoogle Scholar
• Yutzey, K. E., R. L., Kline, and S. F. Konieczny 1989. An internal regulatory element controls troponin I gene expression. Mol. Cell. Biol. 9: 1397-1405.
   PubMed Web of Science ®Google Scholar
• Zerler, B., R. J., Roberts, M. B., Mathews, and E. Mo ran 1987. Different functional domains of the adenovirus El A gene are involved in regulation of host cell cycle products. Mol. Cell. Biol. 7: 821-829.
   PubMed Web of Science ®Google Scholar