Interactions of Phosphatidylinositol Kinase, GTPase-Activating Protein (GAP), and GAP-Associated Proteins with the Colony-Stimulating Factor 1 Receptor

Literature Cited

• Auger, K. R., L. A. Serunian, S. P. Soltoff, P. Libby, and L. Cantley. 1989. PDGF-dependent tyrosine phosphorylation stimulates production of novel polyphosphoinositides in intact cells. Cell 57:167-175.
   PubMed Web of Science ®Google Scholar
• Chabot, B., D. A. Stephenson, V. M. Chapman, P. Besmer, and A. Bernstein. 1988. The proto-oncogene c-kit encoding a transmembrane tyrosine kinase receptor maps to the mouse W locus. Nature (London) 335:88-89.
   PubMed Web of Science ®Google Scholar
• Coughlin, S. R., J. A. Escobedo, and L. T. Williams. 1989. Role of phosphatidylinositol kinase in PDGF receptor signal transduction. Science 243:1191-1194.
   PubMed Web of Science ®Google Scholar
• Courtneidge, S., and A. Heber. 1987. An 81 kd protein complexed with middle T antigen and pp60c-src: a possible phosphatidylinositol kinase. Cell 50:1031-1037.
   PubMed Web of Science ®Google Scholar
• Downing, J. R., B. L. Margolis, A. Zilberstein, R. A. Ashmun, A. Ullrich, C. J. Sherr, and J. Schlessinger. 1989. Phospholipase C-τ, a substrate for PDGF receptor kinase, is not phosphorylated on tyrosine during the mitogenic response to CSF-1. EMBO J. 8:3345-3350.
   PubMed Web of Science ®Google Scholar
• Ellis, C., M. Moran, F. McCormick, and T. Pawson. 1990. Phosphorylation of GAP and GAP-associated proteins by transforming and mitogenic tyrosine kinases. Nature (London) 343:377-381.
   PubMed Web of Science ®Google Scholar
• Escobedo, J. A., and L. T. Williams. 1988. A PDGF receptor domain essential for mitogenesis but not for many other responses to PDGF. Nature (London) 335:85-87.
   PubMed Web of Science ®Google Scholar
• Fukui, Y., and H. Hanafusa. 1989. Phosphatidylinositol kinase activity associates with viral p60src protein. Mol. Cell. Biol. 9:1651-1658.
   PubMedGoogle Scholar
• Kaplan, D. R., D. K. Morrison, G. Wong, F. McCormick, and L. T. Williams. 1990. PDGF β-receptor stimulates tyrosine phosphorylation of GAP and association of GAP with signaling complex. Cell 61:125-133.
   PubMed Web of Science ®Google Scholar
• Kaplan, D. R., M. Whitman, B. Schaffhausen, D. C. Pallas, M. White, L. Cantley, and T. M. Roberts. 1987. Common elements in growth factor stimulation and oncogenic transformation: 85 kd phosphoprotein and phosphotidylinositol kinase activity. Cell 50:1021-1029.
   PubMed Web of Science ®Google Scholar
• Kazlauskas, A., and J. A. Cooper. 1989. Autophosphorylation of the PDGF receptor in the kinase insert region regulates interactions with cell proteins. Cell 58:1121-1133.
   PubMedGoogle Scholar
• Kazlauskas, A., C. Ellis, T. Pawson, and J. A. Cooper. 1990. Binding of GAP to activated PDGF receptors. Science 247:1578-1581.
   PubMedGoogle Scholar
• Lee, P. L., D. E. Johnson, L. S. Cousens, V. A. Fried, and L. T. Williams. 1989. Purification and complementary DNA cloning of a receptor for basic fibroblast growth factor. Science 245:57-60.
   PubMed Web of Science ®Google Scholar
• Macara, I. G., G. V. Marinetti, and P. C. Balduzzi. 1984. Transforming protein of avian sarcoma virus UR2 is associated with phosphatidylinositol kinase activity: possible role in tumorigenesis. Proc. Natl. Acad. Sci. USA 81:2728-2732.
   PubMed Web of Science ®Google Scholar
• Margolis, B., S. G. Rhee, S. Felder, M. Mervic, R. Lyall, A. Levitzki, A. Ullrich, A. Zilberstein, and J. Schlessinger. 1989. EGF induces phosphorylation of phospholipase C-II: a potential mechanism for EGF receptor signalling. Cell 57:1101-1107.
   PubMed Web of Science ®Google Scholar
• Matsui, T., M. Heidaran, T. Miki, N. Popescu, W. La Rochelle, M. Kraus, J. Pierce, and S. Aaronson. 1989. Isolation of a novel receptor cDNA establishes the existence of two PDGF receptor genes. Science 243:800-804.
   PubMed Web of Science ®Google Scholar
• McCormick, F. 1989. ras GTPase activating protein: signal transmitter and signal terminator. Cell 56:5-8.
   PubMed Web of Science ®Google Scholar
• Meisenhelder, J., P.-G. Suh, S. G. Rhee, and T. Hunter. 1989. Phospholipase C-τ is a substrate for the PDGF and EGF receptor protein tyrosine kinases in vivo and in vitro. Cell 57:1109-1122.
   PubMed Web of Science ®Google Scholar
• Molloy, C. J., D. P. Bottaro, T. P. Fleming, M. S. Marshall, J. B. Gibbs, and S. A. Aaronson. 1989. PDGF induction of tyrosine phosphorylation of GTPase activating protein. Nature (London) 342:711-714.
   PubMed Web of Science ®Google Scholar
• Morgan, C., J. W. Pollard, and R. Stanley. 1987. Isolation and characterization of a cloned growth factor dependent macrophage cell line, BAC1.2F5. J. Cell. Physiol. 130:420-427.
   PubMed Web of Science ®Google Scholar
• Morrison, D. K., D. R. Kaplan, J. A. Escobedo, U. Rapp, T. M. Roberts, and L. T. Williams. 1989. Direct activation of the serine/threonine kinase activity of Raf-1 through tyrosine phosphorylation by the PDGF β-receptor. Cell 58:649-657.
   PubMed Web of Science ®Google Scholar
• Morrison, D. K., D. R. Kaplan, U. Rapp, and T. M. Roberts. 1988. Signal transduction from membrane to cytoplasm: growth factors and membrane-bound oncogene products increase Raf-1 phosphorylation and associated protein kinase activity. Proc. Natl. Acad. Sci. USA 85:8855-8859.
   PubMed Web of Science ®Google Scholar
• Pawson, T. 1988. Non-catalytic domains of cytoplasmic proteintyrosine kinases: regulatory elements in signal transduction. Oncogene 3:491-495.
   PubMed Web of Science ®Google Scholar
• Pollard, J. W., A. Bartocci, R. Arceci, A. Orlofsky, M. B. Ladner, and E. R. Stanley. 1987. Apparent role of the macrophage growth factor, CSF-1, in placental development. Nature (London) 330:484-486.
   PubMed Web of Science ®Google Scholar
• Regenstreif, L. J., and J. Rossant. 1989. Expression of the c-fms proto-oncogene and the cytokine, CSF-1, during mouse embryogenesis. Dev. Biol. 133:284-294.
   PubMedGoogle Scholar
• Reith, A. D., R. Rottapel, E. Giddens, C. Brady, L. Forrester, and A. Bernstein. 1990. W mutant mice with mild or severe defects contain distinct point mutations in the kinase domain of the c-kit receptor. Genes Dev. 4:390-400.
   PubMed Web of Science ®Google Scholar
• Rohrschneider, L. R., V. M. Rothwell, and N. A. Nicola. 1989. Transformation of murine fibroblasts by a retrovirus encoding the murine c-fms proto-oncogene. Oncogene 4:1015-1022.
   PubMedGoogle Scholar
• Roussel, M. F., T. J. Dull, C. W. Rettemnier, P. Ralph, A. Ullrich, and C. J. Sherr. 1987. Transforming potential of the c-fms proto-oncogene (CSF-1 receptor). Nature (London) 325:549-552.
   PubMed Web of Science ®Google Scholar
• Ruderman, N. B., R. Kapeller, M. F. White, and L. C. Cantley. 1990. Activation of phosphatidylinositol 3-kinase by insulin. Proc. Natl. Acad. Sci. USA 87:1411-1415.
   PubMed Web of Science ®Google Scholar
• Sherr, C. J. 1990. Colony-stimulating factor-1 receptor. Blood 75:1-12.
   PubMedGoogle Scholar
• Sherr, C. J., C. W. Rettenmier, R. Sacca, M. F. Roussel, A. T. Look, and E. R. Stanley. 1985. The c-fms proto-oncogene product is related to the receptor for the mononuclear phagocyte growth factor, CSF-1. Cell 41:665-676.
   PubMed Web of Science ®Google Scholar
• Shibuya, M., S. Yamaguchi, A. Yamane, T. Ikeda, A. Tojo, H. Matsushime, and M. Sato. 1990. Nucleotide sequence and expression of a novel human receptor-type tyrosine kinase gene (flt) closely related to the fms family. Oncogene 5:519-524.
   PubMed Web of Science ®Google Scholar
• Sprenger, F., L. M. Stevens, and C. Nusslein-Volhard. 1989. The Drosophila gene torso encodes a putative receptor tyrosine kinase. Nature (London) 338:478-483.
   PubMedGoogle Scholar
• Stanley, E. R., L. J. Guilbert, R. J. Tushinski, and S. H. Bartehnez. 1983. CSF-1: a mononuclear phagocyte lineagespecific hematopoietic growth factor. J. Cell. Biochem. 21:151-159.
   PubMed Web of Science ®Google Scholar
• Tapley, P., A. Kazlauskas, J. A. Cooper, and L. R. Rohrschneider. 1990. Macrophage colony-stimulating factor-induced tyrosine phosphorylation of c-fms proteins expressed in FDC-P1 and BALB/c 3T3 cells. Mol. Cell. Biol. 10:2528-2538.
   PubMedGoogle Scholar
• Taylor, G. R., M. Reedijk, V. Rothwell, L. Rohrschneider, and T. Pawson. 1989. The unique insert of cellular and viral fms protein tyrosine kinase domains is dispensable for enzymatic and transforming activities. EMBO J. 8:2029-2037.
   PubMedGoogle Scholar
• Trahey, M., and F. McCormick. 1987. A cytoplasmic protein stimulates normal N-ras p21 GTPase, but does not affect oncogenic mutants. Science 238:542-545.
   PubMed Web of Science ®Google Scholar
• Trahey, M., G. Wong, R. Halenbeck, B. Rubinfeld, G. A. Martin, M. Ladner, C. M. Long, W. J. Crosier, K. Watt, K. Koths, and F. McCormick. 1988. Molecular cloning of two types of GAP complementary DNA from human placenta. Science 242:1697-1700.
   PubMed Web of Science ®Google Scholar
• Tushinski, R. J., I. T. Oliver, L. J. Guilbert, P. W. Tynan, J. R. Warner, and E. R. Stanley. 1982. Survival of mononuclear phagocytes depends on a lineage-specific growth factor that the differentiated cells selectively destroy. Cell 28:71-81.
   PubMed Web of Science ®Google Scholar
• van der Geer, P., and T. Hunter. 1990. Identification of tyrosine 706 in the kinase insert as the major colony-stimulating factor 1 (CSF-l)-stimulated autophosphorylation site in the CSF-1 receptor in a murine macrophage cell line. Mol. Cell. Biol. 10:2991-3002.
   PubMedGoogle Scholar
• Varticovski, L., B. Druker, D. Morrison, L. Cantley, and T. Roberts. 1989. The colony stimulating factor-1 receptor associates with and activates phosphatidylinositol-3 kinase. Nature (London) 342:699-702.
   PubMed Web of Science ®Google Scholar
• Vogel, U. S., R. A. F. Dixon, M. D. Schaber, R. E. Diehl, M. S. Marshall, E. M. Scolnick, I. S. Sigal, and J. B. Gibbs. 1988. Cloning of bovine GAP and its interaction with oncogenic ras p21. Nature (London) 335:90-93.
   PubMed Web of Science ®Google Scholar
• Wahl, M. I., T. O. Daniel, and G. Carpenter. 1988. Antiphosphotyrosine recovery of phospholipase C activity after EGF treatment of A-431 cells. Science 241:968-969.
   PubMedGoogle Scholar
• Wahl, M. I., S. Nishibe, P.-G. Suh, S. G. Rhee, and G. Carpenter. 1989. Epidermal growth factor stimulates tyrosine phosphorylation of phospholipase C-II independently of receptor internalization and extracellular calcium. Proc. Natl. Acad. Sci. USA 86:1568-1572.
   PubMed Web of Science ®Google Scholar
• Weinmaster, G., M. J. Zoller, M. Smith, E. Hinze, and T. Pawson. 1984. Mutagenesis of Fujinami sarcoma virus: evidence that tyrosine phosphorylation of P130gag-fps modulates its biological activity. Cell 37:559-568.
   PubMedGoogle Scholar
• Whitman, M., D. R. Kaplan, T. M. Roberts, and L. Cantley. 1987. Evidence for two distinct phosphatidylinositol kinases in fibroblasts. Biochem. J. 247:165-174.
   PubMed Web of Science ®Google Scholar
• Whitman, M., D. R. Kaplan, B. Schaffhausen, L. Cantley, and T. M. Roberts. 1985. Association of phosphatidylinositol kinase activity with polyoma middle-T competent for transformation. Nature (London) 315:239-242.
   PubMed Web of Science ®Google Scholar
• Woolford, J., A. McAuliffe, and L. R. Rohrschneider. 1988. Activation of the feline c-fms proto-oncogene: multiple alterations are required to generate a fully transformed phenotype. Cell 55:965-977.
   PubMed Web of Science ®Google Scholar
• Woolford, J., V. Rothwell, and L. Rohrschneider. 1985. Characterization of the human c-fms gene product and its expression in cells of the monocyte-macrophage lineage. Mol. Cell. Biol. 5:3458-3466.
   PubMed Web of Science ®Google Scholar
• Yarden, Y., J. A. Escobedo, W.-J. Kuang, T. L. Yang-Feng, T. O. Daniel, P. M. Tremble, E. Y. Chen, M. E. Ando, R. N. Harkins, U. Francke, V. A. Fried, A. Ullrich, and L. T. Williams. 1986. Structure of the receptor for platelet-derived growth factor helps define a family of closely related growth factor receptors. Nature (London) 323:226-232.
   PubMed Web of Science ®Google Scholar
• Yarden, Y., W.-J. Kuang, T. Yang-Feng, L. Coussens, S. Munemitsu, T. J. Dull, E. Chen, J. Schlessinger, U. Francke, and A. Ullrich. 1987. Human proto-oncogene c-kit: a new cell surface receptor tyrosine kinase for an unidentified ligand. EMBO J. 6:3341-3351.
   PubMed Web of Science ®Google Scholar