RNA Polymerase II Mutants Defective in Transcription of a Subset of Genes

Literature Cited

• Allison, L. Α., Μ. Moyle, Μ. Shales, and C. J. Ingles. 1985. Extensive homology among the largest subunits of eukaryotic and prokaryotic RNA polymerases. Cell 42:599–610.
   PubMed Web of Science ®Google Scholar
• Arndt, K., C. Styles, and G. R. Fink. 1989. A suppressor of a HIS4 transcriptional defect encodes a protein with homology to the catalytic subunit of protein phosphatases. Cell 56:527–537.
   PubMedGoogle Scholar
• Barany, F. 1985. Two-codon insertion mutagenesis of plasmid genes by using single-stranded hexameric oligonucleotides. Proc. Natl. Acad. Sci. USA 82:4202–4206.
   PubMedGoogle Scholar
• Boeke, J. D., J. Trueheart, G. Natsoulis, and G. R. Fink. 1987. 5-Fluoroorotic acid as a selective agent in yeast molecular genetics. Methods Enzymol. 154:164–175.
   PubMed Web of Science ®Google Scholar
• Carle, G. F., and M. V. Olson. 1985. An electrophoretic karyotype for yeast. Proc. Natl. Acad. Sci. USA 82:3756–3760.
   PubMed Web of Science ®Google Scholar
• Coulter, D. E., and A. L. Greenleaf. 1982. Properties of mutationally altered RNA polymerase II of Drosophila. J. Biol. Chem. 257:1945–1952.
   PubMedGoogle Scholar
• Falkenburg, D., B. Dworniczak, D. M. Faust, and Ε. Κ. F. Bautz. 1987. RNA polymerase II of Drosophila. Relation of its 140,000 Μ subunit to the beta subunit of Escherichia coli RNA polymerase. J. Mol. Biol. 195:929–937.
   PubMedGoogle Scholar
• Glass, R. E., A. Honda, and A. Ishihama. 1986. Genetic studies on the β subunit of Escherichia coli RNA polymerase IX. The role of the carboxy-terminus in enzyme assembly. Mol. Gen. Genet. 203:492–495.
   PubMedGoogle Scholar
• Glass, R. E., S. T. Jones, V. Nene, T. Nomura, N. Fujita, and A. Ishihama. 1986. Genetic studies on the β subunit of Escherichia coli RNA polymerase VIII. Localisation of a region involved in promoter selectivity. Mol. Gen. Genet. 203:487–491.
   PubMedGoogle Scholar
• Greenleaf, A. L. 1983. Amanitin-resistant RNA polymerase II mutations are in the enzyme's largest subunit. J. Biol. Chem. 258:13403–13406.
   PubMedGoogle Scholar
• Greenleaf, A. L., J. R. Weeks, R. A. Voelker, S. Ohnishi, and B. Dickson. 1980. Genetic and biochemical characterization of mutants at an RNA polymerase II locus in Drosophila melanogaster. Cell 21:785–792.
   PubMedGoogle Scholar
• Guarente, L. 1987. Regulatory proteins in yeast. Annu. Rev. Genet. 21:425–452.
   PubMedGoogle Scholar
• Guarente, L. 1987. UASs and enhancers: common mechanisms of transcriptional activation in yeast and mammals. Cell 52:303–305.
   Google Scholar
• Hirsch, J. P., and S. A. Henry. 1986. Expression of the Saccharomyces cerevisiae inositol-1-phosphate synthase (INO1) gene is regulated by factors that affect phospholipid synthesis. Mol. Cell. Biol. 6:3320–3328.
   PubMedGoogle Scholar
• Hitzeman, R. Α., F. E. Hague, J. S. Hayflick, C. Y. Chen, P. H. Seeburg, and R. Dernyk. 1982. The primary structure of the Saccharomyces cerevisiae gene for 3-phosphoglycerate kinase. Nucleic Acids Res. 10:7791–7808.
   PubMed Web of Science ®Google Scholar
• Hoffman, C. S., and F. Winston. 1987. A ten-minute DNA preparation from yeast efficiently releases autonomous plasmids for transformation of Escherichia coli. Gene 57:267–272.
   PubMed Web of Science ®Google Scholar
• Ingles, C. J., H. J. Himmelfarb, M. Shales, A. L. Greenleaf, and J. D. Friesen. 1984. Identification, molecular cloning, and mutagenesis of Saccharomyces cerevisiae RNA polymerase genes. Proc. Natl. Acad. Sci. USA 81:2157–2161.
   PubMed Web of Science ®Google Scholar
• Kolodziej, P., and R. A. Young. 1989. The RNA polymerase II subunit RPB3 is an essential component of the mRNA transcription apparatus. Mol. Cell. Biol. 9:5387–5394.
   PubMedGoogle Scholar
• Ma, H., S. Kunes, P. J. Schatz, and D. Botstein. 1987. Plasmid construction by homologous recombination in yeast. Gene 58:201–216.
   PubMed Web of Science ®Google Scholar
• Mann, C., J.-M. Buhler, K. Treich, and A. Sentenac. 1987. RPC40, a unique gene for a subunit shared between yeast RNA polymerases A and C. Cell 48:627–637.
   PubMedGoogle Scholar
• McKnight, S., and R. Tjian. 1986. Transcriptional selectivity of viral genes in mammalian cells. Cell 46:795–805.
   PubMed Web of Science ®Google Scholar
• Mitchell, P. J., and R. Tjian. 1989. Transcriptional regulation in mammalian cells by sequence-specific DNA binding proteins. Science 245:371–378.
   PubMed Web of Science ®Google Scholar
• Mortin, Μ. Α., and T. C. Kaufman. 1982. Developmental genetics of a temperature sensitive RNA polymerase II mutation in Drosophila melanogaster. Mol. Gen. Genet. 187:120–125.
   PubMedGoogle Scholar
• Mortin, Μ. Α., and T. C. Kaufman. 1984. Developmental effects of a temperature sensitive RNA polymerase II mutation in Drosophila melanogaster. Dev. Biol. 103:343–354.
   PubMedGoogle Scholar
• Mortin, Μ. Α., and G. Lefevre, Jr. 1981. An RNA polymerase II mutation in Drosophila melanogaster that mimics Ultrabithorax. Chromosoma 82:237–247.
   PubMedGoogle Scholar
• Nomura, T., A. Ishihama, M. Kajitani, T. Takahashi, N. Nakada, and K. Yoshinaga. 1984. Promoter selectivity of Escherichia coli RNA polymerase II: altered promoter selection by mutant holoenzymes. Mol. Gen. Genet. 193:8–16.
   PubMedGoogle Scholar
• Nonet, M., C. Scafe, J. Sexton, and R. Young. 1987. Eucaryotic RNA polymerase conditional mutant that rapidly ceases mRNA synthesis. Mol. Cell. Biol. 7:1602–1611.
   PubMedGoogle Scholar
• Ovchinnikov, Υ. Α., G. S. Monastyrskaya, V. V. Gubanov, S. O. Guryev, O. Y. Chertov, N. N. Modyanov, V. A. Grinkevich, I. A. Makarova, T. V. Marchenko, I. N. Polovnikova, V. M. Lipkin, and E. D. Sverdlov. 1981. The primary sequence of Escherichia coli RNA polymerase. Nucleotide sequence of the rpoB gene and amino acid sequence of the beta-subunit. Eur. J. Biochem. 116:621–629.
   PubMedGoogle Scholar
• Riva, M., S. Memet, J.-Y. Micouin, J. Huet, I. Treich, J. Dassa, R. Young, J.-M. Buhler, A. Sentenac, and P. Fromageot. 1986. Isolation of structural genes for yeast RNA polymerases by immunological screening. Proc. Natl. Acad. Sci. USA 83:1554–1558.
   PubMed Web of Science ®Google Scholar
• Rogalski, T. M., and D. L. Riddle. 1988. A Caenorhabditis elegans RNA polymerase II gene, ama-1 IV, and nearby essential genes. Genetics 118:61–74.
   PubMedGoogle Scholar
• Scafe, C., C. Martin, M. Nonet, S. Podos, S. Okamura, and R. A. Young. 1990. Conditional mutations occur predominantly in highly conserved residues of RNA polymerase II subunits. Mol. Cell. Biol. 10:1270–1275.
   PubMedGoogle Scholar
• Sentenac, A. 1985. Eukaryotic RNA polymerases. Crit. Rev. Biochem. 18:31–91.
   PubMed Web of Science ®Google Scholar
• Simpson, R. B. 1979. The molecular topography of RNA polymerase-promoter interaction. Cell 18:277–285.
   PubMed Web of Science ®Google Scholar
• St. John, T. P., and R. W. Davis. 1981. The organization and transcription of the galactose gene cluster of Saccharomyces. J. Mol. Biol. 152:285–315.
   PubMedGoogle Scholar
• Struhl, K., and D. E. Hill. 1987. Two related regulatory sequences are required for maximal induction of Saccharomyces cerevisiae HIS3 transcription. Mol. Cell. Biol. 7:104–110.
   PubMedGoogle Scholar
• Sweetser, D., M. Nonet, and R. A. Young. 1987. Prokaryotic and eukaryotic RNA polymerases have homologous core subunits. Proc. Natl. Acad. Sci. USA 84:1192–1196.
   PubMed Web of Science ®Google Scholar
• Woychik, Ν. Α., and R. A. Young. 1989. RNA polymerase II subunit RPB4 is essential for high- and low-temperature yeast cell growth. Mol. Cell. Biol. 9:2854–2859.
   PubMed Web of Science ®Google Scholar
• Young, R. Α., and R. W. Davis. 1983. Yeast RNA polymerase II genes: isolation with antibody probes. Science 222:778–782.
   PubMed Web of Science ®Google Scholar
• Yura, T., and A. Ishihama. 1979. Genetics of bacterial RNA polymerases. Annu. Rev. Genet. 13:59–97.
   PubMed Web of Science ®Google Scholar