Thrombin-Dependent Association of Phosphatidylinositol-3 Kinase with p60^c-src and p59^fyn in Human Platelets

LITERATURE CITED

• Auger, K. R., L. A. Serunian, S. P. Soltoff, P. Libby, and L. C. Cantley. 1989. PDGF-dependent tyrosine phosphorylation stimulates production of novel polyphosphoinositides in intact cells. Cell 57:167–175.
   PubMed Web of Science ®Google Scholar
• Coughlin, S. R., J. A. Escobedo, and L. T. Williams. 1989. Role of phosphatidylinositol kinase in PDGF receptor signal transduction. Science 243:1191–1194.
   PubMed Web of Science ®Google Scholar
• Ferrell, J. E., Jr., and G. S. Martin. 1988. Tyrosine-specific protein phosphorylation is regulated by glycoprotein IIb-IIIa in platelets. Mol. Cell. Biol. 8:3603–3610.
   PubMedGoogle Scholar
• Fukui, Y., and H. Hanafusa. 1989. Phosphatidylinositol kinase activity associates with viral p60src protein. Mol. Cell. Biol. 9:1651–1658.
   PubMedGoogle Scholar
• Golden, A., and J. S. Brugge. 1989. Thrombin treatment induces rapid changes in tyrosine phosphorylation in platelets. Proc. Natl. Acad. Sci. USA 86:901–905.
   PubMed Web of Science ®Google Scholar
• Golden, A., S. P. Nemeth, and J. S. Brugge. 1986. Blood platelets express high levels of the pp60c-src-specific tyrosine kinase activity. Proc. Natl. Acad. Sci. USA 83:852–856.
   PubMedGoogle Scholar
• Gutkind, J. S., and K. C. Robbins. 1989. Translocation of c-fgr protein-tyrosine kinase as a consequence of neutrophil activation. Proc. Natl. Acad. Sci. USA 86:8783–8787.
   PubMed Web of Science ®Google Scholar
• Kaplan, D. R., M. Whitman, B. Schaffhausen, D. C. Pallas, M. White, L. Cantley, and T. M. Roberts. 1987. Common elements in growth factor stimulation and oncogenic transformation: 85kd phosphoprotein and phosphatidylinositol kinase activity. Cell 50:1021–1029.
   PubMed Web of Science ®Google Scholar
• Kaplan, D. R., M. Whitman, B. Schaffhausen, L. Raptis, R. L. Garcea, D. Pallas, T. M. Roberts, and L. Cantley. 1986. Phosphatidyl metabolism and polyoma mediated transformation. Proc. Natl. Acad. Sci. USA 83:3624–3628.
   PubMedGoogle Scholar
• Kawakami, T., Y. Kawakami, S. A. Aaronson, and K. C. Robbins. 1988. Acquisition of transforming properties by fyn, a normal src-related human gene. Proc. Natl. Acad. Sci. USA 85:3870–3874.
   PubMed Web of Science ®Google Scholar
• Kawakami, Y., M. Fume, and T. Kawakami. 1989. Identification of fyn-encoded proteins in normal human blood cells. Oncogene 4:389–391.
   PubMedGoogle Scholar
• Ley, T. J., N. L. Connolly, S. Katamine, M. S. C. Cheah, R. M. Senior, and K. C. Robbins. 1989. Tissue-specific expression and developmental regulation of the human fgr proto-oncogene. Mol. Cell. Biol. 9:92–99.
   PubMedGoogle Scholar
• Meisenhelder, J., P.-G. Suh, S. G. Rhee, and T. Hunter. 1989. Phospholipase C-gamma is a substrate for the PDGF and EGF receptor protein-tyrosine kinases in vivo and in vitro. Cell 57:1109–1122.
   PubMed Web of Science ®Google Scholar
• MoUoy, C. J., D. P. Bottaro, T. P. Fleming, M. S. Marshall, J. B. Gibbs, and S. A. Aaronson. 1989. PDGF induction of tyrosine phosphorylation of GTPase activating protein. Nature (London) 342:711–714.
   PubMedGoogle Scholar
• Morgan, W. C., D. R. Kaplan, D. C. Pallas, and T. M. Roberts. 1988. Recombinant retroviruses that transduce middle T antigen cDNAs derived from polyomavirus mutants: separation of focus correlations with kinase activities in vitro. J. Virol. 62:3407–3414.
   PubMedGoogle Scholar
• Morrison, D. K., D. R. Kaplan, J. A. Escobedo, U. R. Rapp, T. M. Roberts, and L. T. Williams. 1989. Direct activation of the serine/threonine kinase activity of Raf-1 through tyrosine phosphorylation by the PDGF beta-receptor. Cell 58:649–657.
   PubMed Web of Science ®Google Scholar
• Nolan, R. D., and E. G. Lapetina. 1990. Thrombin stimulates the production of a novel polyphosphoinositide in human platelets. J. Biol. Chem. 265:2441–2445.
   PubMed Web of Science ®Google Scholar
• Piwnica-Worms, H., D. R. Kaplan, M. Whitman, T. M. Roberts. 1986. Retrovirus shuttle vector for study of kinase activities of pp60c-src synthesized in vitro and overproduced in vivo. Mol. Cell. Biol. 6:2033–2040.
   PubMedGoogle Scholar
• Sudol, M. 1988. Expression of proto-oncogenes in neural tissues. Brain Res. 472:391–403.
   PubMedGoogle Scholar
• Talmage, D. A., R. Freund, A. T. Younf, J. Dahl, C. J. Dawe, and T. L. Benjamin. 1989. Phosphorylation of middle T by pp60c-src: a switch for binding of phosphatidylinositol-3 kinase and optimal tumorigenesis. Cell 59:55–65.
   PubMed Web of Science ®Google Scholar
• Whitman, M., C. P. Downes, M. Keeler, T. Keller, and L. Cantley. 1988. Type I phosphatidylinositol kinase makes a novel inositol phospholipid, phosphatidylinositol-3-phosphate. Nature (London) 332:644–646.
   PubMed Web of Science ®Google Scholar
• Whitman, M., D. R. Kaplan, B. Schaffhausen, L. Cantley, and T. M. Roberts. 1985. Association of phosphatidylinositol kinase activity with polyoma middle T competent for transformation. Nature (London) 315:239–242.
   PubMed Web of Science ®Google Scholar