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Gene Expression

A 36-Kilodalton Cellular Transcription Factor Mediates an Indirect Interaction of Human T-Cell Leukemia/Lymphoma Virus Type I TAX1 with a Responsive Element in the Viral Long Terminal Repeat

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Pages 4192-4201 | Received 24 Jan 1990, Accepted 02 May 1990, Published online: 31 Mar 2023

Literature Cited

  • Altman, R., D. Harrich, J. A. Garcia, and R. B. Gaynor. 1988. Human T-cell leukemia virus types 1 and 2 exhibit different DNase I protection proteins. J. Virol. 62:1339-1346.
  • Baldwin, A. S., and P. A. Sharp. 1987. Binding of a nuclear factor to a regulatory sequence in the promoter of the mouse H-2Kb class 1 major histocompatibility gene. Mol. Cell. Biol. 7:305-313.
  • Ballard, D. W., E. Bohnlein, J. W. Lowenthal, Y. Wano, B. R. Franza, and W. C. Greene. 1988. HTLV-1 tax induces cellular proteins that activate the kB element in the IL-2 receptor a gene. Science 241:1652-1655.
  • Bittner, M., P. Kupferer, and C. Morris. 1980. Electrophoretic transfer of proteins and nucleic acids from slab gels to diazoben-zyloxymethyl cellulose or nitrocellulose sheets. Anal. Biochem. 102:459-471.
  • Brady, J. N., K. T. Jeang, J. Duvall, and G. Khoury. 1987. Identification of p40x-responsive regulatory sequences within human T-cell leukemia virus type 1 long terminal repeat. J. Virol. 61:2175-2181.
  • Briggs, M. R., J. T. Kadonaga, S. P. Bell, and R. Tjian. 1986. Purification and biochemical characterization of the promoter-specific transcription factor, Sp1. Science 234:47-52.
  • Brown, R. S., C. Sander, and P. Argos. 1985. The primary structure of transcription factor TFIIIA has 12 consecutive repeats. FEBS Lett. 186:271-274.
  • Cann, A. J., J. D. Rosenblatt, W. Wachsman, and I. S. Y. Chen. 1989. In vitro mutagenesis of the human T-cell leukemia virus types I and II tax genes. J. Virol. 63:1474-1479.
  • Chiu, R., W. J. Boyle, J. Meek, T. Smeal, T. Hunter, and M. Karin. 1988. The c-fos protein interacts with c-jun/AP-1 to stimulate transcription of AP-1 responsive genes. Cell 54:541-552.
  • DeCaprio, J. A., J. W. Ludlow, J. Figge, J.-Y. Shew, C.-M. Huang, W.-H. Lee, E. Marsilio, E. Paucha, and D. M. Livingston. 1988. SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene. Cell 54:275-283.
  • Dignam, J. D., R. M. Lebowitz, and R. G. Roeder. 1983. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res. 11:1475-1489.
  • Dyson, N., P. M. Howley, K. Munger, and E. Harlow. 1989. The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product. Science 243:934-937.
  • Franza, B. R., F. J. Rauscher, S. F. Josephs, and T. Curran. 1988. The fos complex and fos-related antigenes recognize sequence elements that contain AP-1 binding sites. Science 239:1150-1153.
  • Frankel, A. D., D. S. Bredt, and C. O. Pabo. 1988. Tat protein from human immunodeficiency virus forms a metal-linked dimer. Science 240:70-73.
  • Frankel, A. D., L. Chen, R. J. Cotter, and C. O. Pabo. 1988. Dimerization of the tat protein from human immunodeficiency virus: a cysteine-rich peptide mimics the normal metal-linked dimer interface. Proc. Natl. Acad. Sci. USA 85:6297-6300.
  • Fried, M., and D. M. Crothers. 1981. Equilibria and kinetics of lac repressor-operator interactions by polyacrylamide gel electrophoresis. Nucleic Acids Res. 9:6505-6525.
  • Fujii, M., P. Sassone-Corsi, and I. M. Verma. 1988. c-fos promoter trans-activation by the tax1 protein of human T-cell leukemia virus type I. Proc. Natl. Acad. Sci. USA 85:8526-8530.
  • Gallo, R., F. Wong-Staal, L. Montagnler, W. A. Haseltine, and M. Yoshida. 1988. HIV/HTLV gene nomenclature. Nature (London) 333:504.
  • Garner, M., and M. A. Revzin. 1981. A gel electrophoresis method for quantifying the binding of proteins to specific DNA region: application to components of the Escherichia coli lactose operon regulatory system. Nucleic Acids Res. 9:3047-3060.
  • Giam, C. Z., M. Nerenberg, G. Khoury, and G. Jay. 1988. Expression of the complete human T-cell leukemia virus type 1 pX coding sequence as a functional protein in Escherichia coli. Proc. Natl. Acad. Sci. USA 83:7192-7196.
  • Grussmann, R., C. Dengler, I. Muller-Fleckenstein, B. Fleckenstein, K. McGuire, M.-C. Dokhelar, J. G. Sodroski, and W. A. Haseltine. 1989. Transformation to continuous growth of primary human T lymphocytes by human T-cell leukemia virus type IX-region genes transduced by a Herpesvirus saimiri vector. Proc. Natl. Acad. Sci. USA 86:3351-3355.
  • Green, J. E., C. G. Begley, D. K. Wagner, T. A. Waldmann, and G. Jay. 1989. trans activation of granulocyte-macrophage colony-stimulating factor and the interleukin-2 receptor in transgenic mice carrying the human T-lymphotropic virus type 1 tax gene. Mol. Cell. Biol. 9:4731-4737.
  • Hahn, B., V. Manzari, S. Colombini, G. Franchini, R. C. Gallo, and F. Wong-Staal. 1983. Common site of integration of HTLV in cells of three patients with mature T-cell leukemia-lymphoma. Nature (London) 303:253-256.
  • Haseltine, W. A., J. Sodroski, R. Patarca, D. Briggs, D. Perkins, and F. Wong-Staal. 1984. Structure of 3′ terminal region of type II human lymphotropic virus: evidence for new coding region. Science 225:419-421.
  • Heine, J. W., J. VanDamme, M. DeLey, A. Billiau, and P. DeSomer. 1981. Purification of human fibroblast interferon by zinc chelate chromatography. J. Gen. Virol. 54:47-56.
  • Hidaka, M., J. Inoue, M. Yoshida, and M. Seiki. 1988. Posttranscriptional regulator (rex) of HTLV-1 initiates expression of viral structural proteins but suppresses expression of regulatory proteins. EMBO J. 7:519-523.
  • Himuma, Y., K. Nagata, M. Misoka, M. Nakai, T. Matsuomoto, K. Kiroshita, S. Shirakawa, and I. Miyoshi. 1981. Adult T-cell leukemia: antigen in ATL cell line and detection of antibodies to the antigen in human sera. Proc. Natl. Acad. Sci. USA 78:6476-6480.
  • Hinrichs, S., M. Nerenberg, R. K. Reynolds, G. Khoury, and G. Jay. 1987. A transgenic mouse model for human neurofibromatosis. Science 237:1340-1343.
  • Inoue, J., M. Seiki, T. Taniguchi, S. Tsuru, and M. Yoshida. 1986. Induction of interleukin 2 receptor gene expression by p40x encoded by human T-cell leukemia virus type 1. EMBO J. 5:2883-2888.
  • Jeang, K.-T., I. Boros, J. Brady, M. Radonovich, and G. Khoury. 1988. Characterization of cellular factors that interact with the human T-cell leukemia virus type I p40x-responsive 21-base-pair sequence. J. Virol. 62:4499-4509.
  • Jeang, K.-T., P. R. Shank, and A. Kumar. 1988. Transcriptional activation of homologous viral long terminal repeats by the human immunodeficiency virus type 1 or the human T-cell leukemia virus type I tat proteins occurs in the absence of de novo protein synthesis. Proc. Natl. Acad. Sci. USA 85:8291-8295.
  • Johnson, P. F., W. H. Landschulz, B. J. Graves, and S. L. McKnight. 1987. Identification of a rat liver nuclear protein that binds to the enhancer core element of three animal viruses. Genes Dev. 1:133-146.
  • Kalyanaraman, V. S., M. G. Sarangadharan, Y. Nakao, Y. Ito, T. Aoki, and R. C. Gallo. 1982. Natural antibodies to the structural core protein (p24) of the human T-cell leukemia (lymphoma) retrovirus found in sera of leukemia patients in Japan. Proc. Natl. Acad. Sci. USA 79:1653-1657.
  • Kiyokawa, T., M. Seike, K. Imagawa, F. Shimizu, and M. Yoshida. 1984. Identification of a protein (p40x) encoded by a unique sequence pX of human T-cell leukemia virus type I. Gann 75:747-751.
  • Kouzarides, T., and E. Ziff. 1988. The role of the leucine zipper in the fos-jun interaction. Nature (London) 336:646-651.
  • Lee, T. H., J. E. Coligan, J. G. Sodroski, W. A. Haseltine, S. Z. Salahuddin, F. Wong-Staal, R. C. Gallo, and M. Essex. 1984. Antigens encoded by the 3′-terminal regions of human T-cell leukemia virus: evidence for a functional gene. Science 226:57-61.
  • Lee, C., A. Levin, and D. Branton. 1987. Copper staining: a five minute protein stain for sodium dodecyl sulfate-polyacrylamide gels. Anal. Biochem. 166:308-312.
  • Leung, K., and G. Nabel. 1988. HTLV-1 trans-activator induces interleukin-2 receptor expression through an NF-κB-like factor. Nature (London) 333:776-778.
  • Manley, J. L., A. Fire, A. Cano, P. A. Sharp, and M. L. Getter. 1980. DNA-dependent transcription of adenovirus genes in a soluble whole cell extract. Proc. Natl. Acad. Sci. USA 77:3855-3859.
  • Marriott, S. J., I. Boros, J. F. Duvall, and J. N. Brady. 1989. Indirect binding of human T-cell leukemia virus type tax1 to a responsive element in the viral long terminal repeat. Mol. Cell. Biol. 9:4152-4160.
  • Merril, C. R., D. Goldman, and M. L. VanKeuren. 1982. Simplified silver protein detection and image enhancement methods in polyacrylamide gels. Electrophoresis 3:17-23.
  • Michael, N., D. Spector, P. Mavromara-Nazos, T. M. Kristie, and B. Roizman. 1988. The DNA-binding properties of the major regulatory protein a4 of herpes simplex viruses. Science 239:1531-1534.
  • Miller, J., A. D. McLachlan, and A. Klug. 1985. Repetitive zinc-binding domains in the protein transcription factor IIIA from Xenopus oocytes. EMBO J. 4:1609-1614.
  • Miyatake, S., M. Seiki, M. Yoshida, and K.-I. Arai. 1988. T-cell activation signals and human T-cell leukemia virus type I-encoded p40x protein activate the mouse granulocyte-macrophage colony-stimulating factor gene through a common DNA element. Mol. Cell. Biol. 8:5581-5587.
  • Nagashima, K., M. Yoshida, and M. Seiki. 1986. A single species of pX mRNA of human T-cell leukemia virus type I encodes trans-activator p40x and two other phosphoproteins. J. Virol. 60:394-399.
  • Nagata, K., K. Ohtani, M. Nakamura, and K. Sugainura. 1989. Activation of endogenous c-fos proto-oncogene expression by human T-cell leukemia virus type I-encoded p40tax protein in the human T-cell line, Jurkat. J. Virol. 63:3220-3226.
  • Nerenberg, M., S. H. Hinrichs, R. K. Reynolds, G. Khoury, and G. Jay. 1987. The tat gene of human T-lymphotropic virus type I induces mesenchymal tumors in transgenic mice. Science 237:1324-1329.
  • Nyborg, J. K., W. S. Dynan, I. S. Y. Chen, and W. Wachsman. 1988. Multiple host cell protein binding sites on the HTLV-I LTR: implications for transcriptional regulation. Proc. Natl. Acad. Sci. USA 85:1457-1461.
  • O’Hare, P., and C. R. Goding. 1988. Herpes simplex virus regulatory elements and the immunoglobulin octamer domain bind a common factor and are both targets for virion transactivation. Cell 52:435-445.
  • Paskalis, H., B. K. Felber, and G. N. Pavlakis. 1986. cis-Acting sequences responsible for the transcriptional activation of human T-cell leukemia virus I constitute a conditional enhancer. Proc. Natl. Acad. Sci. USA 83:6558-6562.
  • Poiesz, B. J., F. W. Ruscetti, A. F. Aazdar, P. A. Bunn, J. D. Minna, and R. C. Gallo. 1980. Detection and isolation of type C retrovirus particles from fresh and cultured lymphocytes of a patient with cutaneous T-cell lymphoma. Proc. Natl. Acad. Sci. USA 77:7415-7419.
  • Porath, J., and B. Olin. 1983. Immobilized metal ion affinity adsorption and immobilized metal ion affinity chromatography of biomaterials. Serum protein affinities for gel-immobilized iron and nickel ions. Biochemistry 22:1621-1630.
  • Pozzatti, R., J. Vogel, and G. Jay. 1990. The human T-lymphotropic virus type I tax gene can cooperate with the ras oncogene to induce neoplastic transformation of cells. Mol. Cell. Biol. 10:413-417.
  • Rauscher, F. J., D. R. Cohen, T. Curran, T. J. Bos, P. K. Vogt, D. Bohman, R. Tjian, and B. R. Franza. 1988. Fos-associated protein p39 is the product of the jun proto-oncogene. Science 240:1010-1016.
  • Rauscher, F. J., L. C. Sumbucetti, T. Curran, R. J. Distel, and B. M. Spiegelman. 1988. Common DNA binding site for fos protein complexes and transcription factor AP-1. Cell 52:471-480.
  • Ruben, S., H. Poteat, T. Tan, K. Kawakami, R. Roeder, W. Haseltine, and C. Rosen. 1988. Cellular transcription factors and regulation of IL-2 receptor gene expression by HTLV-I tax gene product. Science 241:89-92.
  • Salahuddin, S. Z., P. D. Markham, F. Wong-Staal, G. Franchini, V. S. Kalyanaraman, and R. C. Gallo. 1983. Restricted expression of human T-cell leukemia-lymphoma virus (HTLV) in transformed human umbilical cord blood lymphocytes. Virology 129:51-64.
  • Sassone-Corsi, P., W. W. Lamph, M. Kamps, and I. M. Verma. 1988. Fos-associated cellular p39 is related to nuclear transcription factor AP-1. Cell 54:553-560.
  • Schreiber, E., P. Matthias, M. Muller, and W. Schaffner. 1988. Identification of novel lymphoid specific octamer binding protein (OTF02B) by proteolytic clipping bandshift assay (PCBA). EMBO J. 7:4221-4229.
  • Seiki, M., A. Hikikoshi, R. Taniguchi, and M. Yoshida. 1985. Expression of the pX gene of HTLV-I: general splicing mechanism in the HTLV family. Science 228:1532-1534.
  • Seiki, M., J. Inoue, M. Hidaka, and M. Yoshida. 1988. Two cis-acting elements responsible for posttranscriptional transregulation of gene expression of human T-cell leukemia virus type I. Proc. Natl. Acad. Sci. USA 85:7124-7128.
  • Sen, R., and D. Baltimore. 1986. Multiple nuclear factors interact with the immunoglobulin enhancer sequences. Cell 46:705-716.
  • Shimotohno, K., M. Takano, T. Teruuchi, and M. Miwa. 1986. Requirement of multiple copies of a 21-nucleotide sequence in the U3 region of human T-celi leukemia virus type I and type II long terminal repeats for trans-acting activation of transcription. Proc. Natl. Acad. Sci. USA 83:8112-8116.
  • Slamon, D. J., K. Shimotohno, M. J. Cline, D. W. Golde, and I. S. Y. Chen. 1984. Identification of the putative transforming protein of the human T-cell leukemia viruses HTLV-I and HTLV II. Science 226:61-75.
  • Sodroski, J. G., C. A. Rosen, and W. A. Haseltine. 1984. Trans-acting transcriptional activation of the long terminal repeat of human T-lyniphotropic viruses in infected cells. Science 225:381-385.
  • Wachsman, W., K. Shimotohno, S. C. Clark, D. W. Golde, and I. S. Y. Chen. 1984. Expression of the 3′ terminal region of human T-cell leukemia viruses. Science 226:177-179.
  • Westin, G., and W. Schaffner. 1988. Heavy metal ions in transcription factors from HeLa cells: Spl, but not octamer transcription factor requires zinc for DNA binding and for activator function. Nucleic Acids Res. 16:5771-5778.
  • Whyte, P., K. J. Buchkovkh, J. M. Horowitz, S. H. Friend, M. Raybuck, R. A. Weinberg, and E. Harlow. 1988. Association between an oncogene and an antioncogene: the adenovirus E1A proteins bind to retinoblastoma gene product. Nature (London) 334:124-129.
  • Wong-Staal, F., B. Hahn, V. Manzari, S. Colombini, A. Francium, E. P. Ackman, and R. C. Gallo. 1983. A survey of human leukemias for sequences of a human retrovirus. Nature (London) 302:626-628.
  • Yoshida, M. I., I. Miyashi, and Y. Hinuma. 1982. Isolation and characterization of retrovirus for cell lines of human adult T-cell leukemia and its replication in the disease. Proc. Natl. Acad. Sci. USA 79:2031-2035.

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