In Vivo Pre-tRNA Processing in Saccharomyces cerevisiae

References

• Atkinson, T., and M. Smith. 1984. Solid phase synthesis of oligodeoxyribonucleotides by the phosphite-triester method, p. 35–81. In M. J. Gait (ed.), Oligonucleotide synthesis: a practical approach. IRL Press, Oxford.
   Google Scholar
• Blatt, B., and H. Feldmann. 1973. Characterization of precursors to tRNA in yeast. FEBS Lett. 37:129–133.
   PubMed Web of Science ®Google Scholar
• Castano, J. G., J. A. Tobian, and M. Zasloff. 1985. Purification and characterization of an endonuclease from Xenopus laevi. ovaries which accurately processes the 3′ terminus of human pre-tRNA Meti (3′ pre-tRNase). J. Biol. Chem. 260:9002–9008.
   PubMedGoogle Scholar
• Church, G. M., and W. Gilbert. 1984. Genomic sequencing. Proc. Natl. Acad. Sci. USA 81:1991–1995.
   PubMed Web of Science ®Google Scholar
• Clark, M. W., and J. Abelson. 1987. The subnuclear localization of tRNA ligase in yeast. J. Cell Biol. 105:1515–1526.
   PubMedGoogle Scholar
• Cryer, D. R., R. Eccleshall, and J. Marmur. 1975. Isolation of Yeast DNA. Methods Cell Biol. 11:39–44.
   Google Scholar
• Culbertson, M. R., and M. Winey. 1989. Split tRNA genes and their products: a paradigm for the study of cell function and evolution. Yeast 5:405–427.
   PubMed Web of Science ®Google Scholar
• DeRobertis, E. M., P. Black, and K. Nishikura. 1981. Intranuclear location of the tRNA splicing enzymes. Cell 23:89–93.
   PubMed Web of Science ®Google Scholar
• DeRobertis, E. M., and M. V. Olson. 1979. Transcription and processing of cloned yeast tyrosine tRNA genes microinjected into frog oocytes. Nature (London) 278:137–143.
   PubMedGoogle Scholar
• Deutscher, M. P. 1970. Reactions at the 3′ terminus of transfer ribonucleic acid: a single enzyme catalyzes the incorporation of adenosine monophosphate and cytidine monophosphate into transfer ribonucleic acid. J. Biol. Chem. 245:4225–4227.
   PubMedGoogle Scholar
• Domdey, H., B. Apostol, R.-J. Lin, A. Newman, E. Brody, and J. Abelson. 1984. Lariat structures are in vivo intermediates in yeast pre-mRNA splicing. Cell 39:611–621.
   PubMed Web of Science ®Google Scholar
• Engelke, D. R., P. Gegenheimer, and J. Abelson. 1985. Nucleo- lytic processing of a tRNA Arg-tRNA Asp dimeric precursor by a homologous component from Saccharomyces cerevisiae. J. Biol. Chem. 260:1271–1279.
   Google Scholar
• Etcheverry, T., M. Salvato, and C. Guthrie. 1982. Recessive lethality of yeast strains carrying the SUP6. suppressor results from loss of a transfer RNA with a unique decoding function. J. Mol. Biol. 158:599–618.
   PubMed Web of Science ®Google Scholar
• Fradin, A., H. Gruhl, and E. Feldmann. 1975. Mapping of yeast tRNAs by two-dimensional electrophoresis on polyacrylamide gels. FEBS Lett. 50:185–189.
   PubMed Web of Science ®Google Scholar
• Frendewey, D., T. Dingermann, L. Cooley, and D. Söll. 1985. Processing of precursor tRNAs in Drosophila. processing of the 3′ end involves an endonucleolytic cleavage and occurs after 5′ end maturation. J. Biol. Chem. 260:449–454.
   PubMedGoogle Scholar
• Ganguly, S., P. A. Sharp, and U. L. RajBhandary. 1988. Saccharomyces cerevisiae SUP5. tRNA gene transcripts are processed by mammalian cell extracts in vitro but are not processed in vivo. J. Biol. Chem. 8:361–370.
   Google Scholar
• Geiduschek, E. P., and G. P. Tocchini-Valentini. 1988. Transcription by RNA polymerase III. Annu. Rev. Biochem. 57: 873–914.
   PubMed Web of Science ®Google Scholar
• Greer, C. 1986. Assembly of a tRNA splicing complex: evidence for concerted excision and joining steps in splicing in vitro. Mol. Cell. Biol. 6:635–644.
   PubMedGoogle Scholar
• Greer, C. L., C. L. Peebles, P. Gegenheimer, and J. Abelson. 1983. Mechanism of action of a yeast RNA ligase in tRNA splicing. Cell 32:537–546.
   PubMed Web of Science ®Google Scholar
• Greer, C. L., D. Söll, and I. Willis. 1987. Substrate recognition and identification of splice sites by the tRNA-splicing endonuclease and ligase from Saccharomyces cerevisiae. Mol. Cell. Biol. 7:76–84.
   Google Scholar
• Guthrie, C., and J. Abelson. 1982. Organization and expression of tRNA genes in Saccharomyces cerevisiae. p. 487–528. In J. N. Strathem, E. W. Jones, and J. R. Broach (ed.), The molecular biology of the yeast Saccharomyces. metabolism and gene expression. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
   Google Scholar
• Hansen, L. J., D. L. Chalker, and S. B. Sandmeyer. 1988. Ty3, a yeast retrotransposon associated with tRNA genes, has homology to animal retroviruses. Mol. Cell. Biol. 8:5245–5256.
   PubMed Web of Science ®Google Scholar
• Ho, C., and J. Abelson. Personal communication.
   Google Scholar
• Ho, C. K., R. Rauhut, U. Vijayraghavan, and J. Abelson. 1990. Accumulation of pre-tRNA splicing “2/3” intermediates in a Saccharomyces cerevisia. mutant. EMBO J. 9:1245–1252.
   PubMedGoogle Scholar
• Hopper, A. K. 1984. Genetic and biochemical studies of RNA processing in yeast, p. 91–117. In D. Apirion (ed.), RNA processing. CRC Press, Boca Raton, Fla.
   Google Scholar
• Hopper, A. K., F. Banks, and V. Evangelidis. 1978. A yeast mutant which accumulates precursor tRNAs. Cell 14:211–219.
   PubMed Web of Science ®Google Scholar
• Hopper, A. K., A. H. Furukawa, H. D. Pham, and N. C. Martin. 1982. Defects in modification of cytoplasmic and mitochondrial transfer RNAs are caused by single nuclear mutations. Cell 28:543–550.
   PubMed Web of Science ®Google Scholar
• Hopper, A. K., and J. Kurjan. 1981. tRNA synthesis: identification of in vivo precursor tRNAs from parental and mutant yeast strains. Nucleic Acids Res. 9:1019–1029.
   PubMed Web of Science ®Google Scholar
• Hopper, A. K., L. D. Schultz, and R. A. Shapiro. 1980. Processing of intervening sequences: a new yeast mutant which fails to excise intervening sequences from precursor tRNAs. Cell 19:741–751.
   PubMed Web of Science ®Google Scholar
• Johnson, J. D., R. Ogden, P. Johnson, J. Abelson, P. Dembeck, and K. Itakura. 1980. Transcription and processing of a yeast tRNA gene containing a modified intervening sequence. Proc. Natl. Acad. Sci. USA 77:2564–2568.
   PubMed Web of Science ®Google Scholar
• Johnson, P. F., and J. Abelson. 1983. The yeast tRNA Tyr gene intron is essential for correct modification of its tRNA product. Nature (London) 302:681–687.
   PubMed Web of Science ®Google Scholar
• Kang, H. S., R. C. Ogden, and J. Abelson. 1980. Two yeast tRNA genes containing intervening sequences, p. 317–331. In W. A. Scott, R. Werner, D. R. Joseph, and J. Schulta (ed.), Mobilization and reassembly of genetic information. Academic Press, Inc., New York.
   Google Scholar
• Klekamp, M. S., and P. A. Weil. 1982. Specific transcription of homologous class III genes in yeast-soluble cell-free extracts. J. Biol. Chem. 257:8432–8441.
   PubMed Web of Science ®Google Scholar
• Knapp, G., J. S. Beckmann, P. F. Johnson, S. A. Fuhrman, and J. Abelson. 1978. Transcription and processing of intervening sequences in yeast tRNA genes. Cell 14:221–236.
   PubMed Web of Science ®Google Scholar
• Knapp, G., R. C. Ogden, C. L. Peebles, and J. Abelson. 1979. Splicing of yeast tRNA precursors: structure of the reaction intermediates. Cell 18:37–45.
   PubMed Web of Science ®Google Scholar
• Kruger, K., P. J. Grabowski, A. J. Zaug, J. Sands, D. E. Gottschling, and T. R. Cech. 1982. Self-splicing RNA: autoextension and autocyclization of the ribosomal RNA intervening sequence of Tetrahymena. Cell 31:147–157.
   PubMed Web of Science ®Google Scholar
• Laten, H., J. Gorman, and R. M. Bock. 1978. Isopentyladenosine deficient tRNA from an antisuppressor mutant of Saccharomyces cerevisiae. Nucleic Acids Res. 5:4329–4342.
   PubMed Web of Science ®Google Scholar
• Lee, J.-Y., and D. R. Engelke. 1989. Partial characterization of an RNA component that copurifies with Saccharomyces cerevisia. RNase P. Mol. Cell. Biol. 9:2536–2543.
   PubMedGoogle Scholar
• Leontis, N., A. DaLio, M. Strobel, and D. Engelke. 1988. Effects of tRNA-intron structure on cleavage of precursor tRNAs, by RNase P from Saccharomyces cerevisiae. Nucleic Acids Res. 16:2537–2552.
   PubMedGoogle Scholar
• Lo, R. Y. C., J. B. Bell, and K. L. Roy. 1982. Dihydrouridine- deficient tRNAs in Saccharomyces cerevisiae. Nucleic Acids Res. 10:889–902.
   PubMedGoogle Scholar
• Maniatis, T., E. F. Fritsch, and J. Sambrook. 1982. Molecular cloning: a laboratory manual. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
   Google Scholar
• McCraith, S. M., and E. M. Phizicky. 1990. A highly specific phosphatase from Saccharomyces cerevisia. implicated in tRNA splicing. Mol. Cell. Biol. 10:1049–1055.
   PubMedGoogle Scholar
• McCraith, S. M., and E. M. Phizicky. Personal communication.
   Google Scholar
• Melton, D. A., and R. Cortese. 1979. Transcription of cloned tRNA genes and the nuclear partitioning of a tRNA precursor. Cell 18:1165–1172.
   PubMed Web of Science ®Google Scholar
• Melton, D. A., E. M. DeRobertis, and R. Cortese. 1980. Order and intracellular location of the events involved in the maturation of a spliced tRNA. Nature (London) 284:143–148.
   PubMed Web of Science ®Google Scholar
• Nishikura, K., and E. M. DeRobertis. 1981. RNA processing in microinjected Xenopu. oocytes: sequential addition of base modifications in a spliced transfer RNA. J. Mol. Biol. 145:405–420.
   PubMed Web of Science ®Google Scholar
• O’Connor, J. P. 1986. M.S. thesis. University of Pittsburgh, Pittsburgh, Pa.
   Google Scholar
• O’Connor, J. P. 1990. Ph.D. thesis. University of Pittsburgh, Pittsburgh, Pa.
   Google Scholar
• O’Connor, J. P., and C. L. Peebles. Submitted for publication.
   Google Scholar
• Ogden, R. C., J. S. Beckmann, J. Abelson, H. S. Kang, D. Soil, and O. Schmidt. 1979. In vitro transcription and processing of a yeast tRNA gene containing an intervening sequence. Cell 17:399–406.
   PubMed Web of Science ®Google Scholar
• Ogden, R. C., M.-C. Lee, and G. Knapp. 1984. Transfer RNA splicing in Saccharomyces cerevisiae. defining the substrates. Nucleic Acids Res. 12:9367–9382.
   PubMed Web of Science ®Google Scholar
• Olson, M. V., G. S. Page, A. Sentenac, P. W. Piper, M. Worthington, R. B. Weiss, and B. D. Hall. 1981. Only one of two closely related yeast suppressor tRNA genes contains an intervening sequence. Nature (London) 291:464–469.
   PubMed Web of Science ®Google Scholar
• Peebles, C. L., P. Gegenheimer, and J. Abelson. 1983. Precise excision of intervening sequences from precursor tRNAs by a membrane-associated yeast endonuclease. Cell 32:525–536.
   PubMed Web of Science ®Google Scholar
• Peebles, C. L., R. C. Ogden, G. Knapp, and J. Abelson. 1979. Splicing of yeast tRNA precursors: a two stage reaction. Cell 18:27–35.
   PubMed Web of Science ®Google Scholar
• Peebles, C. L., P. S. Perlman, K. L. Mecklenburg, M. L. Petrillo, J. H. Tabor, K. A. Jarrell, and H.-L. L. 1986. A selfsplicing RNA excises an intron lariat. Cell 44:213–223.
   PubMed Web of Science ®Google Scholar
• Phizicky, E. M. Personal communication.
   Google Scholar
• Phizicky, E. M., R. C. Schwartz, and J. Abelson. 1986. Saccharomyces cerevisia. tRNA ligase: purification of the protein and isolation of the structural gene. J. Biol. Chem. 261:2978–2986.
   PubMed Web of Science ®Google Scholar
• Pixa, G., G. Dirheimer, and G. Keith. 1984. Sequence of tRNA IleIAU from brewer’s yeast. Biochem. Biophys. Res. Commun. 119:905–912.
   PubMedGoogle Scholar
• Rauhut, R., P. R. Green, and J. Abelson. 1990. Yeast tRNA- splicing endonuclease is a heterotrimeric enzyme. J. Biol. Chem. 265:18180–18184.
   PubMedGoogle Scholar
• Reyes, V. M., and J. Abelson. 1988. Substrate recognition and splice site determination in yeast tRNA splicing. Cell 55:719–730.
   PubMed Web of Science ®Google Scholar
• Rubin, G. M. 1973. The nucleotide sequence of Saccharomyces cerevisia. 5.8S ribosomal ribonucleic acid. J. Biol. Chem. 248:3860–3875.
   PubMed Web of Science ®Google Scholar
• Rubin, G. M. 1974. Three forms of the 5.8-S ribosomal RNA species in Saccharomyces cerevisiae. Eur. J. Biochem. 41:197–202.
   PubMedGoogle Scholar
• Standring, D. N., A. Venegas, and W. J. Rutter. 1981. Yeast tRNA Leu3 gene transcribed and spliced in a HeLa cell extract. Proc. Natl. Acad. Sci. USA 78:5963–5967.
   PubMedGoogle Scholar
• Strobel, M. C., and J. Abelson. 1986. Effect of intron mutations on processing and function of Saccharomyces cerevisiae SUP5. tRNA in vitro and in vivo. Mol. Cell. Biol. 6:2663–2673.
   PubMed Web of Science ®Google Scholar
• Stucka, R., and H. Feldmann. 1988. Structure of a Saccharomyces cerevisia. gene encoding minor (AGY)tRNASer. Nucleic Acids Res. 16:35–83.
   Google Scholar
• Szekely, E., H. G. Belford, and C. L. Greer. 1988. Intron sequence and structure requirements for tRNA splicing in Saccharomyces cerevisiae. J. Biol. Chem. 263:13839–13847.
   Google Scholar
• Tanner, N. K., M. M. Hanna, and J. Abelson. 1988. Binding interactions between yeast tRNA ligase and a precursor transfer ribonucleic acid containing two photoreactive uridine analogues. Biochemistry 27:8852–8861.
   PubMed Web of Science ®Google Scholar
• Tobian, J. A., L. Drinkard, and M. Zasloff. 1985. tRNA nuclear transport: defining the critical regions of human tRNA Meti by point mutagenesis. Cell 43:415–422.
   PubMedGoogle Scholar
• van Tol, H., N. Stange, H. J. Gross, and H. Beier. 1987. A human and a plant intron-containing tRNA Tyr gene are both transcribed in a HeLa cell extract but spliced along different pathways. EMBO J. 6:35–41.
   PubMed Web of Science ®Google Scholar
• van Zyl, W. H., N. Willis, and J. Broach. 1989. A general screen for mutants of Saccharomyces cerevisia. deficient in tRNA biosynthesis. Genetics 123:55–68.
   PubMedGoogle Scholar
• Wang, S. S., and A. K. Hopper. 1988. Isolation of a yeast gene involved in species-specific pre-tRNA processing. Mol. Cell. Biol. 8:5140–5149.
   PubMed Web of Science ®Google Scholar
• Winey, M., and M. R. Culbertson. 1988. Mutations affecting the tRNA-splicing endonuclease activity of Saccharomyces cerevisiae. Genetics 118:609–617.
   PubMedGoogle Scholar
• Winey, M., I. Edelman, and M. R. Culbertson. 1989. A synthetic intron in a naturally intronless yeast pre-tRNA is spliced efficiently in vivo. Mol. Cell. Biol. 9:329–331.
   PubMedGoogle Scholar
• Winey, M., M. D. Mendenhall, C. M. Cummins, M. R. Culbertson, and G. Knapp. 1986. Splicing of a yeast proline tRNA containing a novel suppressor mutation in the anticodon stem. J. Mol. Biol. 192:49–63.
   PubMedGoogle Scholar
• Zasloff, M., M. Rosenberg, and T. Santos. 1982. Impaired nuclear transport of a human variant tRNA Meti. Nature (London) 300:81–84.
   PubMed Web of Science ®Google Scholar