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Cell Growth and Development

Epidermal Growth Factor (EGF) Stimulates Association and Kinase Activity of Raf-1 with the EGF Receptor

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Pages 913-919 | Received 28 Aug 1990, Accepted 15 Nov 1990, Published online: 31 Mar 2023

REFERENCES

  • Baccarini, M., D. M. Sabatini, H. App, U. R. Rapp, and E. R. Stanley. 1990. Colony-stimulating factor-1 (CSF-1) stimulates the temperature-dependent phosphorylation and activation of the raf-1 proto-oncogene product. EMBO J. 9:3649-3657.
  • Beck, T. W., M. Huleihel, M. Gunnell, T. I. Bonner, and U. R. Rapp. 1987. A complete coding sequence of the human a-raf-1 oncogene and transforming activity of a human a-raf carrying retrovirus. Nucleic Acids Res. 15:595-609.
  • Blackshear, P. J., D. M. Haupt, H. App, and U. R. Rapp. 1990. Insulin activates the Raf-1 protein kinase. J. Biol. Chem. 265:12131-12134.
  • Blenis, J., and R. L. Erikson. 1986. Stimulation of ribosomal protein S6 kinase activity by pp60v-src or by serum: dissociation from phorbol ester stimulating activity. Proc. Natl. Acad. Sci. USA 83:1733-1737.
  • Bonner, T. I., H. Oppermann, P. Seeburg, S. B. Kerby, M. A. Gunnell, A. C. Young, and U. R. Rapp. 1986. The complete coding sequence of the human Raf oncogene and the corresponding structure of the c-Raf-1 gene. Nucleic Acids Res. 14:1009-1015.
  • Bradford, M. M. 1976. A rapid and sensitive method for quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:248-254.
  • Carroll, M. P., I. Clark-Lewis, U. R. Rapp, and W. S. May. 1990. Interleukin-3 and granulocyte-macrophage colony-stimulating factor mediate rapid phosphorylation and activation of cytosolic c-raf. J. Biol. Chem. 265:19812-19817.
  • Cooper, A. A., B. M. Sefton, and T. Hunter. 1983. Detection and quantification of phosphotyrosine in proteins. Methods En-zymol. 99:387-402.
  • Erikson, E., and J. L. Mailer. 1986. Purification and characterization of a protein kinase from Xenopus eggs. J. Biol. Chem. 261:350-355.
  • Felder, S., K. MiUer, G. Mochien, A. Ullrich, J. Schlessinger, and C. R. Hopkins. 1990. Kinase activity controls the sorting of the epidermal growth factor receptor within the multivesicular body. Cell 61:623-634.
  • Goldstein, J. L., R. G. W. Anderson, and M. S. Brown. 1979. Coated pits, coated residues, and receptor-mediated endocyto-sis. Nature (London) 279:679-685.
  • Goldstein, J. L., M. S. Brown, R. G. W. Anderson, D. W. Russell, and W. J. Schneider. 1985. Receptor-mediated endocy-tosis: concepts emerging from the LDL receptor system. Annu. Rev. Cell Biol. 1:1-39.
  • Heidecker, G., J. L. Cleveland, T. Beck, M. Huleihel, W. Kolch, S. M. Storm, and U. R. Rapp. 1989. Role of Raf and myc oncogenes in signal transduction, p. 339-374. In N. Colburn (ed.), Genes and signal transduction in multistage carcinogenesis. Marcel Dekker, Inc., New York.
  • Heidecker, G., M. Huleihel, J. L. Cleveland, W. Kolch, T. W. Beck, P. Lloyd, T. Pawson, and U. R. Rapp. 1990. Mutational activation of c-Raf-1 and definition of the minimal transforming sequence. Mol. Cell. Biol. 10:2503-2512.
  • Honegger, A. M., T. J. Dull, S. Felder, E. Van Obberberghen, F. Bellot, D. Szapary, A. Schmidt, A. Ullrich, and J. Schlessinger. 1987. Point mutation at the ATP binding site of EGF receptor abolishes protein tyrosine kinase activity and alters cellular routing. Cell 51:199-209.
  • Honegger, A. M., D. Szapary, A. Schmidt, R. Lyall, E. Van Obberberghen, T. J. Dull, A. Ullrich, and J. Schlessinger. 1987. A mutant epidermal growth factor receptor with defective protein tyrosine kinase is unable to stimulate proto-oncogene expression and DNA synthesis. Mol. Cell. Biol. 7:4567-4571.
  • Hunter, T., and B. M. Sefton. 1980. Proc. Natl. Acad. Sci. USA 77:1311-1315.
  • Ikawa, S., M. Fukai, Y. Neyama, N. Tamacki, Y. Yamamoto, and K. Toyoshima. 1988. B-Raf, a new member of the Raf family, is activated by DNA rearrangement. Mol. Cell. Biol. 8:2651-2654.
  • Jamal, S., and E. Ziff. 1990. Transactivation of c-fos and β-actin genes by Raf as a step in early response to transmembrane signals. Science 344:463-466.
  • Jeno, P., L. M. Ballou, I. Novak-Hofer, and G. Thomas. 1988. Identification and characterization of a mitogen-activated S6 kinase. Proc. Natl. Acad. Sci. USA 85:406-410.
  • Jeno, P., N. Jüggi, H. Luther, M. Seigmann, and G. Thomas. 1989. Purification and characterization of a 40 S ribosomal protein S6 kinase from vandate-stimulated Swiss 3T3 cells. J. Biol. Chem. 264:1293-1297.
  • Kaibuchi, K., Y. Fukumoto, N. Oku, Y. Hori, T. Yamamoto, K. Toyoshima, and Y. Takai. 1989. Activation of the serum response element and 12-O-tetradecanoylphorbol-13-acetate response element by the activated c-Raf-1 protein in a manner independent of protein kinase C. J. Biol. Chem. 264:20855-20858.
  • Kolch, W., A. M. Schultz, H. Opperman, and U. R. Rapp. 1988. Preparation of raf-oncogene-specific antiserum with raf protein produced in E. coli. Biochim. Biophys. Acta 949:233-239.
  • Kovacina, K. S., K. Yonezawa, D. L. Brautigan, N. K. Tonks, U. R. Rapp, and R. A. Roth. 1990. Insulin activates the kinase activity of the Raf-1 proto oncogene by increasing its serine phosphorylation. J. Biol. Chem. 265:12115-12118.
  • Livneh, E., R. Prywes, O. Kashles, N. Reiss, I. Sasson, Y. Mory, A. Ullrich, and J. Schlessinger. 1986. Reconstitution of human epidermal growth factor receptors and its deletion mutants in cultured hamster cells. J. Biol. Chem. 261:12490-12497.
  • Livneh, E., N. Reiss, E. Berent, A. Ullrich, and J. Schlessinger. 1987. An insertational mutant of epidermal growth factor allows dissection of diverse receptor functions. EMBO J. 6:2669-2676.
  • Margolis, B., F. Bellot, A. M. Honegger, A. Ullrich, J. Schlessinger, and A. Zilberstein. 1990. Tyrosine kinase activity is essential for the association of phospholipase C-γ with the epidermal growth factor receptor. Mol. Cell. Biol. 10:435-441.
  • Margolis, B., S. G. Rhee, S. Felder, M. Mervic, R. Lyall, A. Levitzki, A. Ullrich, A. Zilberstein, and J. Schlessinger. 1989. EGF induces tyrosine phosphorylation of phospholipase C-il: a potential mechanism for EGF receptor signaling. Cell 57:1101-1107.
  • Meisenhelder, J., P. G. Sun, S. G. Rhee, and T. Hunter. 1989. Phospholipase C-γ is a substrate for the PDGF and EGF receptor protein-tyrosine kinases in vivo and in vitro. Cell 57:1109-1122.
  • Morrison, D. K., D. R. Kaplan, J. A. Escobedo, U. R. Rapp, T. M. Roberts, and L. T. Williams. 1989. Direct activation of the serine/threonine kinase activity of the proto-oncogene raf-1 through tyrosine phosphorylation by the PDGF b-receptor. Cell 58:648-657.
  • Morrison, D. K., D. R. Kaplan, U. R. Rapp, and T. M. Roberts. 1988. Signal transduction from membrane to cytoplasm: growth factors and membrane-bound oncogene products increase Raf-1 phosphorylation and associated protein kinase activity. Proc. Natl. Acad. Sci. USA 85:8855-8859.
  • Nishizuka, Y. 1986. Studies and perspectives of protein kinase C. Science 233:305-312.
  • Olah, Z., S. Komoly, N. Nagashima, F. Joo, U. R. Rapp, and W. B. Anderson. Exp. Brain Res., in press.
  • Rapp, U. R., J. L. Cleveland, T. I. Bonner, and S. M. Storm. 1988. The raf oncogenes, p. 213-253. In T. Curran, E. P. Reddy, and A. Skalka (ed.), The oncogene handbook. Elsevier Science Publishers, The Netherlands.
  • Rapp, U. R., J. L. Cleveland, S. M. Storm, T. W. Beck, and M. Huleihel. 1987. Transformation by Raf and myc oncogenes, p. 55-74. In S. A. Aaronson, J. Bishop, T. Sugimura, M. Terada, K. Toyoshima, and P. K. Vogt (ed.), Oncogenes and cancer. Japan Scientific Press, Tokyo.
  • Rapp, U. R., G. Heidecker, M. Huleihel, J. L. Cleveland, W. C. Choi, T. Pawson, J. N. Ihle, and W. B. Anderson. 1988. Raf family serine/threonine protein kinases in mitogen signal transduction. Cold Spring Harbor Symp. Quant. Biol. 53:173-184.
  • Rapp, U. R., J. Troppmair, M. Carroll, and W. S. May. Curr. Top. Microbiol. Immunol., in press.
  • Ray, L. B., and T. W. Sturgill. 1988. Characterization of insulin-stimulated microtubule-associated protein kinase. J. Biol. Chem. 263:12721-12727.
  • Rossomando, A. J., D. M. Payne, M. J. Weber, and T. W. Sturgill. 1989. Evidence that pp42, a major tyrosine kinase target protein, is a mitogen-activated serine/threonine protein kinase. Proc. Natl. Acad. Sci. USA 86:6940-6943.
  • Siegel, J. N., R. D. Klausner, U. R. Rapp, and L. E. Samelson. 1990. T cell antigen receptor stimulation activates the c-raf kinase exclusively via serine/threonine phosphorylation. J. Biol. Chem. 265:18472-18480.
  • Sithanandam, G., W. Kolch, F.-M. Duh, and U. R. Rapp. Oncogene, in press.
  • Smith, M. R., S. J. DeGudicibus, and D. W. Stacey. 1986. Requirement for c-ras proteins during viral oncogene transformation. Nature (London) 320:540-543.
  • Smith, M. R., G. Heidecker, U. R. Rapp, and H. F. Kung. 1990. Induction of transformation and DNA synthesis after microinjection of Raf proteins. Mol. Cell. Biol. 10:3828-3833.
  • Storm, S. M., J. L. Cleveland, and U. R. Rapp. 1990. Expression of Raf family proto oncogenes in normal mouse tissues. Oncogene 5:345-351.
  • Tabarini, D., J. Heinrich, and O. M. Rosen. 1985. Activation of S6 kinase activity of 3T3-L-1 by insulin and phorbol ester. Proc. Natl. Acad. Sci. USA 82:4369-4373.
  • Turner, B. C., U. R. Rapp, H. App, M. Green, K. Dobashi, and J. C. Reed. Proc. Natl. Acad. Sci. USA, in press.
  • Ullrich, A., and J. Schlessinger. 1990. Signal transduction by receptor with tyrosine kinase activity. Cell 61:203-212.
  • Wahl, M., S. Nishebe, P.-G. Suh, S.-G. Rhee, and Z. Carpenter. 1989. Epidermal growth factor stimulates tyrosine phosphorylation of phospholipase C-II independently of receptor internalization and extracellular calcium. Proc. Natl. Acad. Sci. USA 86:1568-1572.
  • Wasylyk, C., B. Wasylyk, G. Heidecker, M. Huleihel, and U. R. Rapp. 1989. Expression of raf oncogenes activates the transcription factor PEA1. Mol. Cell. Biol. 9:2247-2250.

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