REFERENCES
- Beug, H., P. A. Blundell, and T. Graf. 1987. Reversibility of differentiation and proliferative capacity in avian myelomono- cytic cells transformed by tsE26 leukemia virus. Genes Dev. 1:277–286.
- Biedenkapp, H., U. Borgmeyer, A. E. Sippel, and K.-H. Klempnauer. 1988. Viral myb oncogene encodes a sequence-specific DNA binding activity. Nature (London) 335:835–837.
- Bishop, J. M. 1987. The molecular genetics of cancer. Science 235:305–311.
- Boyle, W. J., J. S. Lipsick, and M. A. Baluda. 1986. Antibodies to the evolutionarily conserved aminoterminal region of the v-myb-encoded protein detect the c-myb protein in widely divergent metazoan species. Proc. Natl. Acad. Sci. USA 83: 4685–4689.
- Chen, C., and H. Okayama. 1987. High-efficiency transformation of mammalian cells by plasmid DNA. Mol. Cell. Biol. 7:2745–2752.
- Chen, E. Y., and P. H. Seeburg. 1985. Supercoil sequencing: a fast and simple method for sequencing plasmid DNA. DNA 4:165–168.
- Clarke, M. F., J. F. Kukowska-Latallo, E. H. Westin, M. Smith, and E. V. Prochownik. 1988. Constitutive expression of a c-myb cDNA blocks Friend murine erythroleukemia cell differentiation. Mol. Cell. Biol. 8:884–892.
- Clurman, B. E., and W. S. Hayward. 1989. Multiple protooncogene activations in avian leukosis virus-induced lymphomas: evidence for stage specific events. Mol. Cell. Biol. 9:2657–2664.
- Dudek, H., and E. P. Reddy. 1989. Identification of two translational products for c-myb. Oncogene 4:1061–1066.
- Durban, E. M., and D. Boettiger. 1981. Replicating, differentiated macrophages can serve as in vitro targets for transformation by avian myeloblastosis virus. J. Virol. 37:488–492.
- Evan, G. I., G. K. Lewis, and J. M. Bishop. 1984. Isolation of monoclonal antibodies specific for the products of the avian oncogene myb. Mol. Cell. Biol. 4:2843–2850.
- Garcia, A., K. LaMontagne, D. Reavis, U. Stober-Grasser, and J. S. Lipsick. 1991. Determinants of sequence-specific DNA- binding by p48v-myb. Oncogene 6:265–274.
- Gerondakis, S., and J. M. Bishop. 1986. Structure of the protein encoded by the chicken proto-oncogene c-myb. Mol. Cell. Biol. 6:3677–3684.
- Golay, J., M. Introna, and T. Graf. 1988. A single point mutation in the N-ets oncogene affects both erythroid and myelomonocytic cell differentiation. Cell 55:1147–1158.
- Gonda, T. J., C. Buckmaster, and R. G. Ramsay. 1989. Activation of c-myb by carboxyl-terminal truncation: relationship to transformation of murine haemopoietic cells in vitro. EMBO J. 8:1777–1783.
- Gonda, T. J., R. G. Ramsay, and G. R. Johnson. 1989. Murine myeloid cell lines derived by in vitro infection with recombinant c-myb retroviruses express myb from rearranged vector proviruses. EMBO J. 8:1767–1775.
- Graf, T. 1973. Two types of target cells for transformation with avian myelocytomatosis virus. Virology 54:398–413.
- Graf, T., A. von Kirchbach, and H. Beug. 1981. Characterization of the hematopoietic target cells of AEV, MC29, and AMV avian leukemia viruses. Exp. Cell Res. 131:331–343.
- Hughes, S. H., J. J. Greenhouse, C. J. Petropoulos, and P. Sutrave. 1987. Adaptor plasmids simplify the insertion of foreign DNA into helper-independent retroviral vectors. J. Virol. 61: 3004–3012.
- Hughes, S. H., K. Mellstrom, E. Kosik, F. Tamanoi, and J. Brugge. 1984. Mutation of a termination codon affects src initiation. Mol. Cell. Biol. 4:1738–1746.
- Ibanez, C. E., and J. S. Lipsick. 1988. Structural and functional domains of the myb oncogene: requirements for nuclear transport, myeloid transformation, and colony formation. J. Virol. 62:1981–1988.
- Ibanez, C. E., and J. S. Lipsick. 1990. trans activation of gene expression by v-myb. Mol. Cell. Biol. 10:2285–2293.
- Introna, M., J. Golay, J. Frampton, T. Nakano, S. A. Ness, and T. Graf. 1990. Mutations in v-myb alter the differentiation of myelomonocytic cells transformed by the oncogene. Cell 63: 1287–1297.
- Kalkbrenner, F., S. Guehmann, and K. Moelling. 1990. Transcriptional activation by human c-myb and v-myb genes. Oncogene 5:657–661.
- Kanter, M. R., R. E. Smith, and W. S. Hayward. 1988. Rapid induction of B-cell lymphomas: insertional activation of c-myb by avian leukosis virus. J. Virol. 62:1423–1432.
- Katzen, A. L., T. B. Kornberg, and J. M. Bishop. 1985. Isolation of the proto-oncogene c-myb from Drosophila melanogaster. Cell 41:449–456.
- Klempnauer, K.-H., H. Arnold, and H. Biedenkapp. 1989. Activation of transcription by v-myb: evidence for two different mechanisms. Genes Dev. 3:1582–1589.
- Kornfeld, S., H. Beug, G. Doderlein, and T. Graf. 1983. Detection of avian hematopoietic cell surface antigens with monoclonal antibodies to myeloid cells: their distribution on normal and leukemic cells of various lineages. Exp. Cell Res. 143:383–394.
- Lane, T. N., C. E. Ibanez, T. Graf, and J. S. Lipsick. 1990. Transformation by v-myb correlates with transactivation of gene expression. Mol. Cell. Biol. 10:2591–2598.
- Leprince, D., A. Gegonne, J. Coll, C. de Taisne, A. Schneeberger, C. Lagrou, and D. Stehelin. 1983. A putative second cell-derived oncogene of the avian leukaemia retrovirus E26. Nature (London) 306:395–397.
- Leutz, A., H. Beug, and T. Graf. 1984. Purification and characterization of cMGF, a novel chicken myelomonocytic growth factor. EMBO J. 3:3191–3197.
- Lipsick, J. S. 1987. v-myb does not prevent the expression of c-myb in avian erythroblasts. J. Virol. 61:3284–3287.
- Lipsick, J. S., and C. E. Ibanez. 1987. env-encoded residues are not required for transformation by p48v-myb. J. Virol. 61:933–936.
- Lipsick, J. S., C. E. Ibanez, and M. A. Baluda. 1986. Expression of molecular clones of v-myb in avian and mammalian cells independently of transformation. J. Virol. 59:267–275.
- Lüscher, B., E. Christenson, D. W. Litchfield, E. G. Krebs, and R. N. Eisenman. 1990. Myb DNA binding inhibited by phosphorylation at a site deleted during oncogenic activation. Nature (London) 344:517–522.
- Mandi, Y., T. Veromaa, K. Baranji, A. Miczak, and I. Beladi. 1987. Granulocyte-specific monoclonal antibody inhibiting cytotoxicity reactions in the chicken. Immunobiology 174:292–299.
- Maniatis, T., E. F. Fritsch, and J. Sambrook. 1982. Molecular cloning: a laboratory manual. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
- McMahon, J., K. M. Howe, and R. J. Watson. 1988. The induction of Friend erythroleukemia differentiation is markedly affected by expression of a transfected omyb cDNA. Oncogene 3:717–720.
- Metz, T., and T. Graf. 1991. v-myb and v-ets transform chicken erythroid cells and cooperate both in trans and in cis to induce distinct differentiation phenotypes. Genes Dev. 5:369–380.
- Moelling, K., E. Pfaff, H. Beug, P. Beimling, T. Bunte, H. E. Schaller, and T. Graf. 1985. DNA-binding activity is associated with purified myb proteins from AMV and E26 viruses and is temperature-sensitive for E26 ts mutants. Cell 40:983–990.
- Moscovici, C. 1985. Target cells for avian leukemia viruses revisited, p. 177–191. In R. C. Gallo, D. Stehelin, and O. E. Vamier (ed.), Retroviruses and human pathology. Humana Press, Inc., Clifton, N.J.
- Ness, S. A., H. Beug, and T. Graf. 1987. v-myb dominance over v-myc in doubly transformed chick myelomonocytic cells. Cell 51:41–50.
- Ness, S. A., A. Marknell, and T. Graf. 1989. The v-myb oncogene product binds to and activates the promyelocytespecific mim-1 gene. Cell 59:1115–1125.
- Nunn, M. F., P. H. Seeburg, C. Moscovici, and P. H. Duesberg. 1983. Tripartite structure of the avian erythroblastosis virus E26 transforming gene. Nature (London) 306:391–395.
- Peters, C. W. B., A. E. Sippel, M. Vingron, and K.-H. Klempnauer. 1987. Drosophila and vertebrate myb proteins share two conserved regions, one of which functions as a DNA-binding domain. EMBO J. 6:3085–3090.
- Pizer, E., and E. H. Humphries. 1989. RAV-1 insertional mutagenesis: disruption of the c-myb locus and development of avian B-cell lymphomas. J. Virol. 63:1630–1640.
- Ptashne, M. 1988. How eukarytoic transcriptional activators work. Nature (London) 335:683–689.
- Radke, K., H. Beug, S. Kornfeld, and T. Graf. 1982. Transformation of both erythroid and myeloid cells by E26, an avian leukemia virus that contains the myb gene. Cell 31:643–653.
- Ramsay, R. G., S. Ishii, Y. Nishina, G. Soe, and T. J. Gonda. 1989. Characterization of alternate and truncated forms of murine c-myb proteins. Oncogene Res. 4:259–269.
- Rosson, D. 1990. Effects of 5′ and 3′ truncations of the myb gene on the transforming ability of avian myeloblastosis virus (AMV). Virology 175:562–567.
- Rosson, D., and E. P. Reddy. 1986. Nucleotide sequence of chicken c-myb complementary DNA and implications for myb oncogene activation. Nature (London) 319:604–606.
- Sakura, H., C. Kanei-Ishii, T. Nagase, H. Nakagoshi, T. J. Gonda, and S. Ishii. 1989. Delineation of three functional domains of the transcriptional activator encoded by the c-myb protooncogene. Proc. Natl. Acad. Sci. USA 86:5758–5762.
- Shen-Ong, G. L. 1990. The myb oncogene. Biochim. Biophys. Acta 1032:39–52.
- Shen-Ong, G. L., B. Luscher, and R. N. Eisenman. 1989. A second c-myb protein is translated from an alternatively spliced mRNA expressed from normal and 5′-disrupted myb loci. Mol. Cell. Biol. 9:5456–5463.
- Souza, L. M., J. N. Strommer, R. L. Hillyard, M. C. Komaromy, and M. A. Baluda. 1980. Cellular sequences are present in the presumptive avian myeloblastosis virus genome. Proc. Natl. Acad. Sci. USA 77:5177–5181.
- Stober-Grasser, U., and J. S. Lipsick. 1988. Specific amino acid substitutions are not required for transformation by v-myb of avian myeloblastosis virus. J. Virol. 62:1093–1096.
- Weston, K., and J. M. Bishop. 1989. Transcriptional activation by the v-myb oncogene and its cellular progenitor, c-myb. Cell 58:85–93.