3
Views
1
CrossRef citations to date
0
Altmetric
Gene Expression

Liver Cells Contain Constitutive DNase I-Hypersensitive Sites at the Xenobiotic Response Elements 1 and 2 (XRE1 and -2) of the Rat Cytochrome P-4501Al Gene and a Constitutive, Nuclear XRE- Binding Factor That Is Distinct from the Dioxin Receptor

, , , , , , , & show all
Pages 4314-4323 | Received 01 Apr 1991, Accepted 03 Jun 1991, Published online: 31 Mar 2023

References

  • Bagchi, M. K., J. F. Elliston, S. Y. Tsai, D. P. Edwards, M.-J. Tsai, and B. W. O'Malley. 1988. Steroid-dependent interaction of human progesterone receptor with its target enhancer element. Mol. Endocrinol. 2:1221–1229.
  • Beato, M. 1989. Gene regulation by steroid hormones. Cell 56:335–344.
  • Becker, P. B., B. Gloss, W. Schmid, U. Strähle, and G. Schütz. 1986. In vivo protein-DNA interactions in a glucocorticoid response element require the presence of the hormone. Nature (London) 324:686–688.
  • Becker, P. B., R. Renkawitz, and G. Schütz. 1984. Tissuespecific DNase I-hypersensitive sites in the 5′-flanking sequences of the tryptophan oxygenase and tyrosine aminotransferase genes. EMBO J. 3:2015–2020.
  • Cuthill, S., and L. Poellinger. 1988. DNA-binding properties of dioxin receptors in wild-type and mutant mouse hepatoma cells. Biochemistry 27:2978–2982.
  • Cuthill, S., L. Poellinger, and J.-Å. Gustafsson. 1987. The receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin in the mouse hepatoma cell line Hepa 1c1c7. J. Biol. Chem. 262:3477–3481.
  • Cuthill, S., A. Wilhelmsson, and L. Poellinger. 1991. Role of the ligand in intracellular receptor function: receptor affinity determines activation in vitro of the latent dioxin receptor to a DNA-binding form. Mol. Cell. Biol. 11:401–411.
  • Denis, M., L. Poellinger, A.-C. Wikström, and J.-Å. Gustafsson. 1988. Requirement of hormone for thermal conversion of the glucocorticoid receptor to a DNA-binding state. Nature (London) 333:686–688.
  • Denison, M. S., J. M. Fisher, and J. P. Whitlock, Jr. 1988. Inducible, receptor-dependent protein-DNA interactions at a dioxin-responsive transcriptional enhancer. Proc. Natl. Acad. Sci. USA 85:2528–2532.
  • Dignam, J. D., R. M. Lebowitz, and R. G. Roeder. 1983. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res. 11:1475–1489.
  • Durrin, L. K., and J. P. Whitlock, Jr. 1987. In situ protein-DNA interactions at a dioxin-responsive enhancer associated with the cytochrome Pl-450 gene. Mol. Cell. Biol. 7:3008–3011.
  • Durrin, L. K., and J. P. Whitlock, Jr. 1989. 2,3,7,8-Tetrachlo- rodibenzo-p-dioxin-inducible aryl hydrocarbon receptor-mediated change in Cyp1A1 chromatin structure occurs independently of transcription. Mol. Cell. Biol. 9:5733–5737.
  • Einck, L., J. Fagan, and M. Bustin. 1986. Chromatin structure of the cytochrome P-450c gene changes following induction. Biochemistry 25:7062–7068.
  • Fritton, H. P., T. Igo-Kemenes, J. Nowock, U. Strech-Jurk, M. Theisen, and A. E. Sippel. 1984. Alternative sets of DNase I hypersensitive sites characterize the various functional states of the chicken lysozyme gene. Nature (London) 311:163–165.
  • Fritton, H. P., A. E. Sippel, and T. Igo-Kemenes. 1983. Nuclease-hypersensitive sites in the chromatin domain of the chicken lysozyme gene. Nucleic Acids Res. 11:3467–3485.
  • Fujisawa-Sehara, A., K. Sogawa, M. Yamane, and Y. Fujii-Kuriyama. 1987. Characterisation of xenobiotic responsive elements upstream from the drug metabolising cytochrome P-450c gene: a similarity to glucocorticoid response elements. Nucleic Acids Res. 15:4179–4191.
  • Fujisawa-Sehara, A., M. Yamane, and Y. Fujii-Kuriyama. 1988. A DNA-binding factor specific for xenobiotic responsive elements of P-450c gene exists as a cryptic form in cytoplasm: its possible translocation to nucleus. Proc. Natl. Acad. Sci. USA 85:5859–5863.
  • Gorski, K., M. Carneiro, and U. Schibler. 1986. Tissue-specific in vitro transcription from the mouse albumin promoter. Cell 47:767–776.
  • Gustafsson, J.-Å., J. Carlstedt-Duke, L. Poellinger, S. Okret, A.-C. Wikström, M. Brönnegård, M. Gillner, Y. Dong, K. Fuxe, A. Cintra, and L. Agnati. 1987. Biochemistry, molecular biology and physiology of the glucocorticoid receptor. Endocrine Rev. 8:185–234.
  • Hankinson, O. 1983. Dominant and recessive aryl hydrocarbon hydroxylase-deficient mutants of mouse hepatoma line hepa 1, and assignment of recessive mutants to three complementation groups. Somatic Cell Genet. 9:497–514.
  • Hapgood, J., S. Cuthill, M. Denis, L. Poellinger, and J.-Á. Gustafsson. 1989. Specific protein-DNA interactions at a xeno- biotic-responsive element: copurification of dioxin receptor and DNA-binding activity. Proc. Natl. Acad. Sci. USA 86:60–64.
  • Hecht, A., A. Berkenstam, P.-E. Strömstedt, J.-Å. Gustafsson, and A. E. Sippel. 1988. A progesterone responsive element maps to the far upstream steroid dependent DNase hypersensitive site of chicken lysozyme chromatin. EMBO J. 7:2063–2073.
  • Herrera, R. E., P. E. Shaw, and A. Nordheim. 1989. Occupation of the c-fos serum response element in vivo by a multi-protein complex is unaltered by growth factor induction. Nature (London) 340:68–70.
  • Israel, D. I., and J. P. Whitlock, Jr. 1984. Regulation of cytochrome P1-450 gene transcription by 2,3,7,8-tetrachloro- dibenzo-p-dioxin in wild-type and variant mouse hepatoma cells. J. Biol. Chem. 259:5400–5402.
  • Jantzen, H.-M., U. Strähle, B. Gloss, F. Steward, W. Schmid, M. Boshart, R. Miksicek, and G. Schütz. 1987. Cooperativity of glucocorticoid response elements far upstream of the tyrosine aminotransferase gene. Cell 49:29–38.
  • Kumar, V., and P. Chambon. 1988. The estrogen receptor binds tightly to its responsive element as a ligand-induced homodimer. Cell 55:145–156.
  • Landers, J. P., J. Piskorska-Pliszczynska, T. Zacharewski, N. J. Bunce, and S. Safe. 1989. Photoaffinity labeling of the nuclear Ah receptor from mouse Hepa 1c1c7 cells using 2,3,7,8-[3H]tet- rachlorodibenzo-p-dioxin. J. Biol. Chem. 264:18463–18471.
  • Legraverend, C., R. R. Hannah, H. J. Eisen, I. S. Owens, D. W. Nebert, and O. Hankinson. 1982. Regulatory gene product of the Ah locus: characterisation of receptor mutants among mouse hepatoma clones. J. Biol. Chem. 257:6402–6407.
  • Nebert, D. W., and F. J. Gonzalez. 1987. P-450 genes: structure, evolution and regulation. Annu. Rev. Biochem. 56:945–993.
  • Nemoto, T., G. G. F. Mason, A. Wilhelmsson, S. Cuthill, J. Hapgood, J.-Å. Gustafsson, and L. Poellinger. 1990. Activation of the dioxin and glucocorticoid receptors to a DNA-binding state under cell-free conditions. J. Biol. Chem. 265:2269–2277.
  • Neuhold, L. A., Y. Shirayoshi, K. Ozato, J. E. Jones, and D. W. Nebert. 1989. Regulation of mouse CYP1A1 gene expression by dioxin: requirement of two cis-acting elements during induction. Mol. Cell. Biol. 9:2378–2386.
  • Nitsch, D., F. Steward, M. Boshart, R. Mestril, F. Weih, and G. Schütz. 1990. Chromatin structures of the tyrosine rat aminotransferase gene relate to the function of its cis-acting elements. Mol. Cell. Biol. 10:3334–3342.
  • Paulson, K. E., J. E. Darnell, T. Rushmore, and C. B. Pickett. 1990. Analysis of the upstream elements of the xenobiotic compound-inducible and positionally regulated glutathione 5-transferase gene. Mol. Cell. Biol. 10:1841–1852.
  • Poellinger, L., B. K. Yoza, and R. G. Roeder. 1989. Functional cooperativity between protein molecules bound at two distinct sequence elements of the immunoglobulin heavy-chain promoter. Nature (London) 337:573–576.
  • Pongratz, I., J. McGuire, A.-C. Wikström, and L. Poellinger. Unpublished data.
  • Prywes, R., and R. G. Roeder. 1987. Purification of the c-fos enhancer-binding protein. Mol. Cell. Biol. 7:3482–3489.
  • Saatcioglu, F., D. J. Perry, D. S. Pasco, and J. B. Fagan. 1990. Multiple DNA-binding factors interact with overlapping specificities at the aryl hydrocarbon response element of the cytochrome P-450IA1 gene. Mol. Cell. Biol. 10:6408–6416.
  • Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
  • Shaw, P. E., S. Frasch, and A. Nordheim. 1989. Repression of c-fos transcription is mediated through p67srf bound to the SRE. EMBO J. 8:2567–2574.
  • Shaw, P. E., H. Schröter, and A. Nordheim. 1989. The ability of a ternary complex to form over the serum response element correlates with serum inducibility of the human c-fos promoter. Cell 56:563–572.
  • Soderkvist, P., L. Poellinger, R. Toftgård, and J.-Å. Gustafsson. 1988. Differential expression of the cytochrome P-450c and P-450d genes in the rat ventral prostate and liver. Cancer Res. 48:3045–3049.
  • Sogawa, K., A. Fujisawa-Sehara, M. Yamane, and Y. Fujii-Kuriyama. 1986. Location of regulatory elements responsible for drug induction in the rat cytochrome P-450c gene. Proc. Natl. Acad. Sci. USA 83:8044–8048.
  • Sogawa, K., O. Gotoh, K. Kawajiri, and Y. Fujii-Kuriyama. 1984. Distinct organization of methylcholanthrene- and phenobarbital-inducible cytochrome P-450 genes in rat. Proc. Natl. Acad. Sci. USA 81:5066–5070.
  • Strähle, U., M. Boshart, G. Klock, F. Stewart, and G. Schütz. 1989. Glucocorticoid- and progesterone-specific effects are determined by differential expression of the respective hormone receptors. Nature (London) 339:629–632.
  • Treisman, R. 1987. Identification and purification of a polypeptide that binds to the c-fos serum response element. EMBO J. 6:2711–2717.
  • Weih, F., F. Steward, M. Boshart, D. Nitsch, and G. Schutz. 1990. In vivo monitoring of a cAMP-stimulated DNA-binding activity. Genes Dev. 4:1437–1449.
  • Wilhelmsson, A., S. Cuthill, M. Denis, A.-C. Wikstrom, J.-A. Gustafsson, and L. Poellinger. 1990. The specific DNA-binding activity of the dioxin receptor is modulated by the 90kD heat shock protein. EMBO J. 9:69–76.
  • Wilhelmsson, A., A.-C. Wikström, and L. Poellinger. 1986. Polyanionic-binding properties of the receptor for 2,3,7,8-tetra- chlorodibenzo-p-dioxin: a comparison with the glucocorticoid receptor. J. Biol. Chem. 261:13456–13463.
  • Yamamoto, K. R. 1985. Steroid receptor regulated transcription of specific genes and gene networks. Annu. Rev. Genet. 19:205–252.
  • Yanagida, A., K. Sogawa, K.-I. Yasumoto, and Y. Fujii-Kuriyama. 1990. A novel cis-acting DNA element required for a high level of inducible expression of the rat cytochrome P-450c gene. Mol. Cell. Biol. 10:1470–1475.
  • Zaret, K. S., and K. R. Yamamoto. 1984. Reversible and persistent changes in chromatin structure accompany activation of a glucocorticoid-dependent enhancer element. Cell 38:29–38.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.