The Gene Encoding the Transcription Factor SCIP Has Features of an Expressed Retroposon

References

• Ashworth, A., B. Skene, S. Swift, and R. Lovell-Badge. 1990. Zfa is an expressed retroposon derived from an alternative transcript of the Zfx gene. EMBO J. 9:1529–1534.
   PubMedGoogle Scholar
• Beachy, P., M. Krasnow, E. Gavis, and D. Hogness. 1988. An Ultrabithorax protein binds sequences near its own and the Antennapedia P1 promoters. Cell 55:1069–1081.
   PubMedGoogle Scholar
• Bird, A. 1987. CpG islands as gene markers in the vertebrate nucleus. Trends Genet. 3:342–347.
   Web of Science ®Google Scholar
• Bodner, M., J.-L. Castrillo, L. Theill, T. Deerinck, M. Ellisman, and M. Karin. 1988. The pituitary-specific transcription factor GHF-1 is a homeobox-containing protein. Cell 4:505–518.
   Google Scholar
• Boer, P., C. Adra, Y.-F. Lau, and M. McBurney. 1987. The testis-specific phospholglycerate kinase gene pgk-2 is a recruited retroposon. Mol. Cell. Biol. 7:3107–3112.
   PubMed Web of Science ®Google Scholar
• Bögler, O., R. Kuhn, A. Entwistle, E. S. Monuki, G. Wolswijk, G. Lemke, and M. Noble. Unpublished data.
   Google Scholar
• Breathnach, R., and P. Chambon. 1981. Organization and expression of eukaryotic split genes coding for proteins. Annu. Rev. Biochem. 50:349–383.
   PubMed Web of Science ®Google Scholar
• Brockes, J., K. Fields, and M. Raff. 1979. Studies on cultured rat Schwann cells. Establishment of purified populations from cultures of peripheral nerve. Brain Res. 165:105–118.
   PubMed Web of Science ®Google Scholar
• Caput, D., B. Beutler, K. Hartog, R. Thayer, S. Brown-Shimer, and A. Cerami. 1986. Identification of a common nucleotide sequence in the 3′-untranslated region of mRNA molecules specifying inflammatory mediators. Proc. Natl. Acad. Sci. USA 83:1670–1674.
   PubMed Web of Science ®Google Scholar
• Chomczynski, P., and N. Sacchi. 1987. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloro- form extraction. Anal. Biochem. 162:156–159.
   PubMed Web of Science ®Google Scholar
• Clerc, R., L. Corcoran, J. LeBowitz, D. Baltimore, and P. Sharp. 1988. The B-cell-specific Oct-2 protein contains POU box- and homeo box-type domains. Genes Dev. 2:1570–1581.
   PubMed Web of Science ®Google Scholar
• Dahl, H.-H., R. Brown, W. Hutchison, C. Maragos, and G. Brown. 1990. A testis-specific form of the human pyruvate dehydrogenase E1α subunit is coded for by an intronless gene on chromosome 4. Genomics 8:225–232.
   PubMed Web of Science ®Google Scholar
• Devereux, J., P. Haeberl, and O. Smithies. 1984. A comprehensive set of sequence analysis programs for the VAX. Nucleic Acids Res. 12:387–395.
   PubMed Web of Science ®Google Scholar
• Dieckmann, C., and A. Tzagoloff. 1985. Assembly of the mitochondrial membrane system. J. Biol. Chem. 260:1513–1520.
   PubMedGoogle Scholar
• Dynan, W., R. Sazar, R. Tjian, and R. Schimke. 1986. Transcription factor Sp1 recognizes a DNA sequence in the mouse dihydrofolate reductase promoter. Nature (London) 319:246–248.
   PubMedGoogle Scholar
• Dynan, W., and R. Tjian. 1983. The promoter specific transcription factor Sp1 binds to upstream sequences in the SV40 early promoter. Cell 35:79–87.
   PubMed Web of Science ®Google Scholar
• Ephrussi, A., G. Church, S. Tonegawa, and W. Gilbert. 1985. B lineage-specific interactions of an immunoglobulin enhancer with cellular factors in vivo. Science 227:134–140.
   PubMed Web of Science ®Google Scholar
• Fink, G. 1987. Pseudogenes in yeast? Cell 49:5–6.
   PubMedGoogle Scholar
• Graf, L., P. Kaplan, and S. Silagi. 1984. Efficient DNA-mediated transfer of selectable genes and unselected sequences into differentiated and undifferentiated mouse melanoma clones. Somatic Cell Mol. Genet. 10:139–151.
   PubMedGoogle Scholar
• Gruss, P. Personal communication.
   Google Scholar
• Harlow, E., and D. Lane. 1988. Antibodies: a laboratory manual. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
   Google Scholar
• Hatzopoulos, A., A. Stoykova, J. Erselius, M. Goulding, T. Neuman, and P. Gruss. 1990. Structure and expression of the mouse Oct2a and Oct2b, two differentially spliced products of the same gene. Development 109:349–362.
   PubMed Web of Science ®Google Scholar
• He, X., R. Gerrero, D. Simmons, R. Park, C. Lin, L. Swanson, and M. Rosenfeld. 1991. Tst-1, a member of the POU domain gene family, binds the promoter of the gene encoding the cell surface adhesion molecule P0. Mol. Cell. Biol. 11:1739–1744.
   PubMedGoogle Scholar
• He, X., M. Treacy, D. Simmons, H. Ingraham, L. Swanson, and M. Rosenfeld. 1989. Expression of a large family of POU- domain regulatory genes in mammalian brain development. Nature (London) 340:35–42.
   PubMed Web of Science ®Google Scholar
• Herr, W., R. Sturm, R. Clerc, L. Corcoran, D. Baltimore, P. Sharp, H. Ingraham, M. Rosenfeld, M. Finney, G. Ruvkin, and H. Horvitz. 1988. The POU domain: a large conserved region in the mammalian pit-1, Oct-1, Oct-2 and C. elegans unc-86 gene products. Genes Dev. 2:1513–1516.
   PubMed Web of Science ®Google Scholar
• Ingraham, H., R. Chen, H. Mangalam, H. Elsholtz, S. Flynn, C. Lin, D. Simmons, L. Swanson, and M. Rosenfeld. 1988. A tissue-specific transcription factor containing a homeodomain specifies a pituitary phenotype. Cell 55:519–529.
   PubMed Web of Science ®Google Scholar
• Jones, K. A., J. T. Kadonaga, P. J. Rosenfeld, T. J. Kelly, and R. Tjian. 1987. A cellular DNA-binding protein that activates eukaryotic transcription and DNA replication. Cell 48:79–89.
   PubMed Web of Science ®Google Scholar
• Kageyama, R., and I. Pastan. 1989. Molecular cloning and characterization of a human DNA binding factor that represses transcription. Cell 59:815–825.
   PubMedGoogle Scholar
• Killary, A., and R. Fournier. 1984. A genetic analysis of extinction: trans-dominant loci regulate expression of liverspecific traits in hepatoma hybrid cells. Cell 38:523–534.
   PubMedGoogle Scholar
• Kozak, M. 1990. Evaluation of the fidelity of initiation of translation in reticulocyte lysates from commercial sources. Nucleic Acids Res. 18:2828.
   PubMedGoogle Scholar
• Krumlauf, R., P. Holland, J. McVey, and B. Hogan. 1987. Developmental and spatial patterns of expression of the mouse homeobox gene, Hox2.1. Development 99:603–617.
   PubMedGoogle Scholar
• Maniatis, T., E. Fritsch, and J. Sambrook. 1982. Molecular cloning: a laboratory manual. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
   Google Scholar
• McCarrey, J., and K. Thomas. 1987. Human testis-specific Pgk gene lacks introns and possesses characteristics of a processed gene. Nature (London) 326:501–505.
   PubMed Web of Science ®Google Scholar
• Montminy, M., K. Sevarino, J. Wagner, G. Mandel, and R. Goodman. 1986. Identification of a cyclic-AMP-responsive element within the rat somatostatin gene. Proc. Natl. Acad. Sci. USA 83:6682–6686.
   PubMed Web of Science ®Google Scholar
• Monuki, E., R. Kuhn, G. Weinmaster, B. Trapp, and G. Lemke. 1990. Expression and activity of the POU transcription factor SCIP. Science 249:1300–1303.
   PubMedGoogle Scholar
• Monuki, E., G. Weinmaster, R. Kuhn, and G. Lemke. 1989. SCIP: a glial POU domain gene regulated by cyclic AMP. Neuron 3:783–793.
   PubMedGoogle Scholar
• Miiller, M. M., S. Ruppert, W. Schaffner, and P. Matthias. 1988. A cloned octamer transcription factor stimulates transcription from lymphoid-specific promoters in non-B cells. Nature (London) 336:544–551.
   PubMedGoogle Scholar
• Njolstad, P., A. Molven, I. Hordvik, J. Apold, and A. Fjose. 1988. Primary structure, developmentally regulated expression and potential duplication of the zebrafish homeobox gene ZF- 21. Nucleic Acids Res. 16:9097–9111.
   PubMedGoogle Scholar
• Okamoto, K., H. Okazawa, A. Okuda, M. Sakai, M. Muramatsu, and H. Hamada. 1990. A novel octamer binding transcription factor is differentially expressed in mouse embryonic cells. Cell 60:461–472.
   PubMed Web of Science ®Google Scholar
• Porter, S., M. Clark, L. Glaser, and R. Bunge. 1986. Schwann cells stimulated to proliferate in the absence of neurons retain full functional capacity. J. Neurosci. 6:3070–3078.
   PubMedGoogle Scholar
• Rio, D., F. Laski, and G. Rubin. 1986. Identification and immunochemical analysis of biologically active Drosophila P element transposase. Cell 44:21–32.
   PubMed Web of Science ®Google Scholar
• Rosner, M., M. Vigano, K. Ozato, P. Timmons, F. Poirier, P. Rigby, and L. Staudt. 1990. A POU-domain transcription factor in early stem cells and germ cells of the mammalian embryo. Nature (London) 345:686–692.
   PubMed Web of Science ®Google Scholar
• Rüther, U., and B. Müller-Hill. 1983. Easy identification of cDNA clones. EMBO J. 2:1791–1794.
   PubMedGoogle Scholar
• Ruvkun, G., and M. Finney. 1991. Regulation of transcription and cell identity by POU domain proteins. Cell 64:475–478.
   PubMedGoogle Scholar
• Scheidereit, C., J. A. Cromlish, T. Gerster, K. Kawakami, C.-G. Balmaceda, R. Currie, and R. Roeder. 1988. A human lymphoidspecific transcription factor that activates immunoglobulin genes is a homoebox protein. Nature (London) 336:551–557.
   PubMedGoogle Scholar
• Schöler, H., S. Ruppert, N. Suzuki, K. Chowdhury, and P. Gruss. 1990. New type of POU domain in germ-line specific protein Oct-4. Nature (London) 344:435–439.
   PubMed Web of Science ®Google Scholar
• Schreiber, E., P. Matthias, M. Müller, and W. Schaffner. 1989. Rapid detection of octamer binding proteins with "mini-extracts," prepared from a small number of cells. Nucleic Acids Res. 17:6419.
   PubMed Web of Science ®Google Scholar
• Sehgal, A., N. Patil, and M. Chao. 1988. A constitutive promoter directs expression of the nerve growth factor receptor gene. Mol. Cell. Biol. 8:3160–3167.
   PubMed Web of Science ®Google Scholar
• Shaw, G., and R. Kamen. 1986. A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation. Cell 46:659–667.
   PubMed Web of Science ®Google Scholar
• Simeone, A., F. Mavilio, L. Bottero, A. Giampaolo, G. Russo, A. Faiella, E. Boncinelli, and C. Peschle. 1986. A human homeobox gene specifically expressed in spinal cord during embryonic development. Nature (London) 320:763–765.
   PubMedGoogle Scholar
• Sturm, R., G. Das, and W. Herr. 1988. The ubiquitous octamer-binding protein Oct-1 contains a POU domain with a homeo box subdomain. Genes Dev. 2:1582–1599.
   PubMed Web of Science ®Google Scholar
• Suzuki, N., H. Rohdewohld, T. Neuman, P. Gruss, and H. Schöler. 1990. Oct-6: a POU transcription factor expressed in embryonal stem cells and in the developing brain. EMBO J. 9:3723–3732.
   PubMedGoogle Scholar
• Topp, W. 1981. Normal rat cell lines deficient in nuclear thymidine kinase. Virology 113:408–411.
   PubMed Web of Science ®Google Scholar
• Weiner, A., P. Deininger, and A. Efstratiadis. 1986. Nonviral retroposons: genes, pseudogenes, and transposable elements generated by reverse flow of genetic information. Annu. Rev. Biochem. 55:631–661.
   PubMed Web of Science ®Google Scholar
• Zinn, K., D. Dimaio, and T. Maniatis. 1983. Identification of two distinct regulatory regions adjacent to the human ß-interferon gene. Cell 34:865–879.
   PubMed Web of Science ®Google Scholar