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Transcriptional Regulation

Cyclic AMP Response Element-Binding Protein and the Catalytic Subunit of Protein Kinase A Are Present in F9 Embryonal Carcinoma Cells but Are Unable To Activate the Somatostatin Promoter

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Pages 1096-1106 | Received 18 Oct 1991, Accepted 06 Dec 1991, Published online: 31 Mar 2023

References

  • Akerblom, I. E., E. P. Slater, M. Beato, J. D. Baxter, and P. L. Mellon. 1988. Negative regulation by glucocorticoids through interference with a cAMP responsive enhancer. Science 241:350–353.
  • Berkowitz, L. A., and M. Z. Gilman. 1990. Two distinct forms of active transcription factor CREB (cAMP-response-element-binding protein). Proc. Natl. Acad. Sci. USA 87:5258–5262.
  • Berkowitz, L. A., K. T. Riabowol, and M. Z. Gilman. 1989. Multiple sequence elements of a single functional class are required for cyclic AMP-responsiveness of the mouse c-fos promoter. Mol. Cell. Biol. 9:4272–4281.
  • Boshart, M., F. Weih, A. Schmidt, R. E. K. Fournier, and G. Schutz. 1990. A cyclic AMP response element mediates repression of tyrosine aminotransferase gene transcription by the tissue-specific extinguisher locus Tse-1. Cell 61:905–916.
  • Comb, M., N. C. Birnberg, A. Seasholtz, E. Herbert, and H. M. Goodman. 1986. A cyclic AMP- and phorbol ester-inducible DNA element. Nature (London) 323:353–356.
  • Daniel, F., D. Morello, O. Le Bail, P. Chambon, Y. Cayre, and P. Kourilsky. 1983. Structure and expression of the mouse β2-microglobulin gene isolated from somatic and non-expressing teratocarcinoma cells. EMBO. J. 2:1061–1065.
  • Darrow, A. L., R. J. Rickles, L. T. Pecorino, and S. Strickland. 1990. Transcription factor SP1 is important for retinoic acid-induced expression of the tissue plasminogen activator gene during F9 teratocarcinoma cell differentiation. Mol. Cell. Biol. 10:5883–5893.
  • Deutsch, P. J., J. P. Hoeffler, L. J. Jameson, J. C. Lin, and J. F. Habener. 1988. Structural determinants for transcriptional activation by cAMP-responsive DNA elements. J. Biol. Chem. 263:18466–18472.
  • de Wet, J. R., K. V. Wood, M. DeLuca, D. R. Helinski, and S. Subramani. 1987. Firefly luciferase gene: structure and expression in mammalian cells. Mol. Cell. Biol. 7:725–737.
  • Edelman, A. M., D. K. Blumenthal, and E. G. Krebs. 1987. Protein serine/threonine kinases. Annu. Rev. Biochem. 56:567–613.
  • Ellis, M., et al. Unpublished data.
  • Enoch, T., K. Zinn, and T. Maniatis. 1986. Activation of the human β-interferon gene requires an interferon-inducible factor. Mol. Cell. Biol. 6:801–810.
  • Fink, J. S., M. Verhave, S. Kasper, T. Tsukada, G. Mandel, and R. H. Goodman. 1988. The CGTCA sequence motif is essential for biological activity of the vasoactive intestinal peptide gene cAMP-regulated enhancer. Proc. Natl. Acad. Sci. USA 85:6662–6666.
  • Fisch, T. M., R. Prywes, M. Celeste Simon, and R. G. Roeder. 1989. Multiple sequence elements in the c-fos promoter mediate induction by cAMP. Genes Dev. 3:198–211.
  • Foulkes, N. S., E. Borrelli, and P. Sassone-Corsi. 1991. CREM gene: use of alternative DNA-binding domains generates multiple antagonists of cAMP-induced transcription. Cell 64:739–749.
  • Frick, K. K., and C. D. Scher. 1990. Platelet-derived growth factor-stimulated c-myc RNA accumulation in MG-63 human osteosarcoma cells is independent of both protein kinase A and protein kinase C. Mol. Cell. Biol. 10:184–192.
  • Gomariz, R. P., M. J. Lorenzo, L. Cacicedo, A. Vicente, and A. G. Zapata. 1990. Demonstration of immunoreactive vasoactive intestinal peptide (IR-VIP) and somatostatin (IR-SOM) in rat thymus. Brain Behav. Immun. 4:151–161.
  • Gonzalez, G. A., P. Menzel, J. Leonard, W. H. Fischer, and M. R. Montminy. 1991. Characterization of motifs which are critical for activity of the cyclic AMP-responsive transcription factor CREB. Mol. Cell. Biol. 11:1306–1312.
  • Gonzalez, G. A., and M. R. Montminy. 1989. Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133. Cell 59:675–680.
  • Gonzalez, G. A., K. K. Yamamoto, W. H. Fischer, D. Karr, P. Menzel, W. Biggs III, W. W. Vale, and M. R. Montminy. 1989. A cluster of phosphorylation sites on the cyclic AMP-regulated nuclear factor CREB predicted by its sequence. Nature (London) 337:749–752.
  • Goodbourn, S. 1990. Negative regulation of transcriptional initiation in eucaryotes. Biochim. Biophys. Acta 1032:53–77.
  • Hai, T.-Y., F. Liu, W. J. Coukos, and M. R. Green. 1989. Transcription factor ATF cDNA clones: an extensive family of leucine zipper proteins able to selectively form DNA binding heterodimers. Genes Dev. 3:2083–2090.
  • Hardy, S., and T. Shenk. 1988. Adenoviral control regions activated by E1A and the cAMP-response element bind to the same factor. Proc. Natl. Acad. Sci. USA 85:4171–4175.
  • Harshman, K. D., W. S. Moye-Rowley, and C. S. Parker. 1988. Transcriptional activation by the SV40 AP-1 recognition element in yeast is mediated by a factor similar to AP-1 that is distinct from GCN4. Cell 53:321–330.
  • Hemmings, B. A. 1986. cAMP mediated proteolysis of the catalytic subunit of cAMP-dependent protein kinase. FEBS Lett. 196:126–130.
  • Hoeffler, J. P., T. E. Meyer, Y. Yun, J. L. Jameson, and J. F. Habener. 1988. Cyclic AMP-responsive DNA-binding protein: structure based on a cloned placental cDNA. Science 242:1430–1433.
  • Hurst, H. C., and N. C. Jones. 1987. Identification of factors that interact with the E1A-inducible adenovirus E3 promoter. Genes Dev. 1:1132–1146.
  • Hurst, H. C., N. Masson, N. C. Jones, and K. A. W. Lee. 1990. The cellular transcription factor CREB corresponds to activating transcription factor 47 (ATF-47) and forms complexes with a group of polypeptides related to ATF-43. Mol. Cell. Biol. 10:6192–6203.
  • Hyman, S. E., M. Comb, Y. S. Lin, J. Pearlberg, M. R. Green, and H. M. Goodman. 1988. A common trans-acting factor is involved in transcriptional regulation of neurotransmitter genes by cyclic AMP. Mol. Cell. Biol. 8:4225–4233.
  • Jones, N. 1990. Transcriptional regulation by dimerization: two sides to an incestuous relationship. Cell 61:9–11.
  • Kameda, Y. 1989. Distribution of CGRP-, somatostatin-, gala-nin-, VIP-, and substance P-immunoreactive nerve fibers in the chicken carotid body. Cell Tissue Res. 257:623–629.
  • Kanei-Ishii, C., and S. Ishii. 1989. Dual enhancer activities of the cyclic-AMP responsive element with cell type and promoter specificity. Nucleic Acids Res. 17:1521–1537.
  • Lane, E. B. 1982. Monoclonal antibodies provide specific intramolecular markers for the study of epithelial filament organisation. J. Cell Biol. 92:665–673.
  • Lee, C. Q., Y. Yun, J. P. Hoeffler, and J. F. Habener. 1990. Cyclic AMP-responsive transcriptional activation of CREB-327 involves interdependent phosphorylated subdomains. EMBO J. 9:4455–4465.
  • Lee, K. A. W. 1991. Transcriptional regulation by cAMP. Curr. Opinion Cell Biol. 3:953–959.
  • Lee, K. A. W., J. S. Fink, R. H. Goodman, and M. R. Green. 1989. Distinguishable promoter elements are involved in transcriptional activation by E1a and cyclic AMP. Mol. Cell. Biol. 9:4390–4397.
  • Lengyel, A. M., A. Grossman, L. H. Rees, and G. M. Besser. 1989. Dose-dependent effects of vasoactive intestinal polypeptide on somatostatin release from hypothalamic fragments in vitro. Braz. J. Med. Biol. Res. 22:1311–1316.
  • Lin, Y. S., and M. R. Green. 1988. Interaction of a common cellular transcription factor, ATF, with regulatory elements in both Ela- and cyclic AMP-inducible promoters. Proc. Natl. Acad. Sci. USA 85:3396–3400.
  • Lohmann, S. M., and U. Walter. 1984. Regulation of the cellular and subcellular concentrations and distribution of cyclic nucle-otide-dependent protein kinases. Adv. Cyclic Nucleotide Protein Phosphorylation Res. 18:63–117.
  • Maniatis, T., E. F. Fritsch, and J. Sambrook. 1982. Molecular cloning: a laboratory manual. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
  • Martin, G. R. 1975. Teratocarcinoma as a model system for the study of embryogenesis and neoplasia. Cell 5:229–243.
  • McKnight, G. S. 1991. Cyclic AMP second messenger systems. Curr. Opinion Cell Biol. 3:213–217.
  • Meinkoth, J. L., M. R. Montminy, J. S. Fink, and J. R. Feramisco. 1991. Induction of a cAMP-responsive gene in living cells requires the nuclear factor CREB. Mol. Cell. Biol. 11:1759–1764.
  • Mellon, P. L., C. H. Clegg, L. A. Correll, and G. S. McKnight. 1989. Regulation of transcription by cyclic AMP-dependent protein kinase. Proc. Natl. Acad. Sci. USA 86:4887–4891.
  • Montminy, M. R., and L. M. Bilezikjian. 1987. Binding of a nuclear protein to the cyclic-AMP response element of the somatostatin gene. Nature (London) 328:175–178.
  • Montminy, M. R., K. A. Sevarino, J. A. Wagner, G. Mandel, and R. H. Goodman. 1986. Identification of a cyclic-AMP-responsive element within the rat somatostatin gene. Proc. Natl. Acad. Sci. USA 83:6682–6686.
  • Morgenstern, J. P., and H. Land. 1990. A series of mammalian expression vectors and characterization of their expression of a reporter gene in stably and transiently transfected cells. Nucleic Acids Res. 18:1068.
  • Nishimori, K., T. Kohda, J. Fujiwara, and M. Oishi. 1988. Establishment of composite DNA derived from L factor as a plasmid in mouse embryonal carcinoma (F9) cells. Mol. Cell. Biol. 8:2097–2104.
  • O'Dorisio, M. S. 1988. Neuropeptide modulation of the immune response in gut associated lymphoid tissue. Int. J. Neurosci. 38:189–198.
  • Oshima, R. G., L. Abrams, and D. Kulesh. 1990. Activation of an intron enhancer within the keratin 18 gene by expression of c-fos and c-jun in undifferentiated F9 embryonal carcinoma cells. Genes Dev. 4:835–848.
  • Ouellet, T., C. Lampron, M. Lussier, L. Lapointe, and A. Royal. 1990. Differential regulation of keratin 8 and 18 messenger RNAs in differentiating F9 cells. Biochim. Biophys. Acta 1048:194–201.
  • Plet, A., D. Evain, and W. B. Anderson. 1982. Effect of retinoic acid treatment of F9 embryonal carcinoma cells on the activity and distribution of cyclic AMP-dependent protein kinase. J. Biol. Chem. 257:889–893.
  • Rickles, R. J., A. L. Darrow, and S. Strickland. 1989. Differentiation-responsive elements in the 5' region of the mouse tissue plasminogen activator gene confer two-stage regulation by retinoic acid and cyclic AMP in teratocarcinoma cells. Mol. Cell. Biol. 9:1691–1704.
  • Sleigh, M. J. 1986. A nonchromatographic assay for expression of the chloramphenicol acetyltransferase gene in eucaryotic cells. Anal. Biochem. 156:251–256.
  • Stanton, L. W., P. D. Fahrlander, P. M. Tesser, and K. B. Marcu. 1984. Nucleotide sequence comparison of normal and translocated murine c-myc genes. Nature (London) 310:423–425.
  • Strickland, S., and V. Mahdavi. 1978. Induction of differentiation in teratocarcinoma stem cells by retinoic acid. Cell 15:393–403.
  • Strickland, S., K. K. Smith, and K. R. Marotti. 1980. Hormonal induction of differentiation in teratocarcinoma stem cells: generation of parietal endoderm by retinoic acid and dibutyryl cAMP. Cell 21:347–355.
  • Tassios, P. T., and N. B. La Thangue. 1990. A multiplicity of differentiation-regulated ATF-binding site activities in embryonal carcinoma cells with distinct sequence and promoter specificities. New Biol. 2:1123–1134.
  • Tortora, G., and Y. S. Cho-Chung. 1990. Type II regulatory subunit of protein kinase restores cAMP-dependent transcription in a cAMP-unresponsive cell line. J. Biol. Chem. 265:18067–18070.
  • Treisman, R. Unpublished data.
  • Tsukada, T., J. S. Fink, G. Mandel, and R. H. Goodman. 1987. Identification of a region in the human vasoactive intestinal polypeptide gene responsible for regulation by cyclic AMP. J. Biol. Chem. 262:8743–8747.
  • Yamamoto, K. K., G. A. Gonzalez, W. Biggs III, and M. R. Montminy. 1988. Phosphorylation-induced binding and transcriptional efficacy of nuclear factor CREB. Nature (London) 334:494–498.
  • Yamamoto, K. K., G. A. Gonzalez, P. Menzel, J. Rivier, and M. R. Montminy. 1990. Characterization of a bipartite activator domain in transcription factor CREB. Cell 60:611–617.
  • Zinn, K., D. DiMaio, and T. Maniatis. 1983. Identification of two distinct regulatory regions adjacent to the human β-interferon gene. Cell 34:865–879.

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