Human p53 Inhibits Growth in Schizosaccharomyces pombe

REFERENCES

• Baker, S. J., E. R. Fearon, J. Μ. Nigro, S. R. Hamilton, A. C. Preisinger, J. Μ. Jessup, P. van Tuinen, D. H. Ledbetter, D. F. Barker, Y. Nakamura, R. White, and B. Vogelstein. 1989. Chromosome 17 deletions and p53 gene mutations in colorectal carcinomas. Science 244:217–221.
   PubMed Web of Science ®Google Scholar
• Bargonetti, J., P. N. Friedman, S. E. Kern, B. Vogelstein, and C. Prives. 1991. Wild-type but not mutant p53 immunopurified proteins bind to sequences adjacent to the SV40 origin of replication. Cell 65:1083–1091.
   PubMed Web of Science ®Google Scholar
• Beach, D., L. Rodgers, and J. Gould. 1985. ranl+ controls the transition from mitotic division to meiosis in fission yeast. Curr. Genet. 10:297–311.
   PubMedGoogle Scholar
• Bischoff, J. R. Unpublished data.
   Google Scholar
• Bischoff, J. R., P. N. Friedman, D. R. Marshak, C. Prives, and D. Beach. 1990. Human p53 is phosphorylated by p60-cdc2 and cyclin B-cdc2. Proc. Natl. Acad. Sci. USA 87:4766–4770.
   PubMed Web of Science ®Google Scholar
• Booher, R. N., C. E. Alpha, J. S. Hyams, and D. H. Beach. 1989. The fission yeast cdc2/cdcl3/sucl protein kinase: regulation of catalytic activity and nuclear localization. Cell 58:485–497.
   PubMed Web of Science ®Google Scholar
• Carroll, D., and D. R. Marshak. 1989. Serum-stimulated cell growth causes oscillations in casein kinase II activity. J. Biol. Chem. 264:7345–7348.
   PubMed Web of Science ®Google Scholar
• Chen, P.-L., Y. Chen, R. Bookstein, and W.-H. Lee. 1990. Genetic mechanism of tumor suppression by the human p53 gene. Science 250:1576–1580.
   PubMed Web of Science ®Google Scholar
• Diller, L., J. Kassel, C. E. Nelson, Μ. A. Gryka, G. Litwak, Μ. Gebhardt, B. Bressac, Μ. Ozturk, S. J. Baker, B. Vogelstein, and S. H. Friend. 1990. p53 functions as a cell cycle control protein in osteosarcomas. Mol. Cell. Biol. 10:5772–5781.
   PubMed Web of Science ®Google Scholar
• Eliyahu, D., N. Goldfinger, O. Pinhasi-Kimhi, G. Shaulsky, Y. Skurnik, N. Arai, V. Rotter, and Μ. Oren. 1988. Meth A fibrosarcoma cells express two transforming mutant p53 species. Oncogene 3:313–321.
   PubMed Web of Science ®Google Scholar
• Eliyahu, D., A. Raz, P. Gruss, D. Givol, and Μ. Oren. 1984. Participation of p53 cellular tumour antigen in transformation of normal embryonic cells. Nature (London) 312:646–649.
   PubMed Web of Science ®Google Scholar
• Fields, S., and S. K. Jang. 1990. Presence of a transcription activating sequence in the p53 protein. Science 249:1046–1049.
   PubMed Web of Science ®Google Scholar
• Finlay, C. A., P. W. Hinds, and A. J. Levine. 1989. The p53 protooncogene can act as a suppressor of transformation. Cell 57:1083–1093.
   PubMed Web of Science ®Google Scholar
• Finlay, C. A., P. W. Hinds, T.-H. Tan, D. Eliyahu, Μ. Oren, and A. J. Levine. 1988. Activating mutations for transformation by p53 produce a gene product that forms an hsc70-p53 complex with an altered half-life. Mol. Cell. Biol. 8:531–539.
   PubMed Web of Science ®Google Scholar
• Gannon, J. V., and D. P. Lane. 1991. Protein synthesis required to anchor a mutant p53 protein which is temperature-sensitive for nuclear transport. Nature (London) 349:802–805.
   PubMedGoogle Scholar
• Harlow, E., L. V. Crawford, D. C. Pim, and N. Μ. Williamson. 1981. Monoclonal antibodies specific for simian virus 40 tumor antigen. J. Virol. 39:861–869.
   PubMed Web of Science ®Google Scholar
• Harlow, E., N. Μ. Williamson, R. Ralston, D. Μ. Helfman, and T. E. Adams. 1985. Molecular cloning and in vitro expression of a cDNA clone for human cellular tumor antigen p53. Mol. Cell. Biol. 7:1601–1610.
   Google Scholar
• Hinds, P., C. Finlay, and A. J. Levine. 1989. Mutation is required to activate the p53 gene for cooperation with the ras oncogene and transformation. J. Virol. 63:739–746.
   PubMed Web of Science ®Google Scholar
• Jenkins, J. R., K. Rudge, and G. A. Currie. 1984. Cellular immortalization by a cDNA clone encoding the transformation- associated phosphoprotein p53. Nature (London) 312:651–653.
   PubMed Web of Science ®Google Scholar
• Karlund, J. K., and Μ. P. Czech. 1988. Insulin-like growth factor I and insulin rapidly increase casein kinase II activity in BALB/c 3T3 fibroblasts. J. Biol. Chem. 263:15872–15875.
   PubMedGoogle Scholar
• Kern, S. E., K. W. Kinzler, A. Bruskin, D. Jarosz, P. Friedman, C. Prives, and B. Vogelstein. 1991. Identification of p53 as a sequence-specific DNA-binding protein. Science 252:1708–1711.
   PubMed Web of Science ®Google Scholar
• Lane, D. P., and S. Benchimol. 1990. p53: oncogene or antioncogene? Genes Dev. 4:1–8.
   PubMed Web of Science ®Google Scholar
• Lane, D. P., and L. V. Crawford. 1979. T antigen is bound to a host protein in SV40-transformed cells. Nature (London) 278:261–263.
   PubMed Web of Science ®Google Scholar
• Levine, A., J. Momand, and C. A. Finlay. 1991. The p53 tumour suppressor gene. Nature (London) 351:453–456.
   PubMed Web of Science ®Google Scholar
• Levine, A. J. 1990. The p53 protein and its interactions with the oncogene products of the small DNA tumor viruses. Virology 177:419–426.
   PubMedGoogle Scholar
• Linzer, D. I. H., and A. J. Levine. 1979. Characterization of a 54,000 MW cellular SV40 tumor antigen present in SV40- transformed cells and uninfected embryonal carcinoma cells. Cell 17:43–52.
   PubMed Web of Science ®Google Scholar
• Martinez, J., I. Georgoff, J. Martinez, and A. J. Levine. 1991. Cellular localization and cell cycle regulation by a temperaturesensitive p53 protein. Genes Dev. 5:151–159.
   PubMed Web of Science ®Google Scholar
• Maundrell, K. 1990. nmtl of fission yeast: a highly transcribed gene completely repressed by thiamine. J. Biol. Chem. 265:10857–10864.
   PubMed Web of Science ®Google Scholar
• Meek, D. Μ., S. Simon, U. Kikkawa, and W. Eckhart. 1990. The p53 tumour suppressor protein is phosphorylated at serine 389 by casein kinase IL. EMBO J. 9:3253–3260.
   PubMed Web of Science ®Google Scholar
• Meek, D. W., and W. Eckhart. 1988. Phosphorylation of p53 in normal and simian virus 40-transformed NIH 3T3 cells. Mol. Cell. Biol. 8:461–465.
   PubMedGoogle Scholar
• Mercer, W. E., Μ. T. Shields, Μ. Amin, G. J. Sauve, E. Appella, J. W. Romano, and S. J. Ullrich. 1990. Negative growth regulation in a gliobastoma tumor cell line that conditionally expresses human wild-type p53. Proc. Natl. Acad. Sci. USA 87:6166–6170.
   PubMed Web of Science ®Google Scholar
• Michalovitz, D., O. Halevy, and Μ. Oren. 1990. Conditional inhibition of transformation and of cell proliferation by a temperature-sensitive mutant of p53. Cell 62:671–681.
   PubMed Web of Science ®Google Scholar
• Milner, J., and E. A. Medcalf. 1991. Cotranslation of activated mutant p53 with wild-type drives the wild-type p53 protein into the mutant conformation. Cell 65:765–774.
   PubMed Web of Science ®Google Scholar
• Mowat, Μ., A. Cheng, N. Kimura, A. Bernstein, and S. Benchimol. 1985. Rearrangments of the cellular p53 gene in erythroleukemic cells transformed by Friend virus. Nature (London) 314:633–636.
   PubMed Web of Science ®Google Scholar
• Nigro, J. Μ., S. J. Baker, A. C. Preisinger, J. Μ. Jessup, R. Hostetter, K. Cleary, S. H. Bigner, N. Davidson, S. Baylin, P. Deville, T. Glover, F. S. Collins, A. Weston, R. Modali, C. C. Harris, and B. Vogelstein. 1989. Mutations in the p53 gene occur in diverse human tumour types. Nature (London) 342:705–708.
   PubMed Web of Science ®Google Scholar
• Nigro, J. Μ., R. Sikorski, S. I. Reed, and B. Vogelstein. 1992. Human p53 and CDC2Hs genes combine to inhibit the proliferation of Saccharomyces cerevisiae. Mol. Cell. Biol. 12:1357–1365.
   PubMed Web of Science ®Google Scholar
• Nurse, P., and Y. Bisset. 1981. Gene required in G1 for commitment to cell cycle and in G2 for control of mitosis in fission yeast. Nature (London) 392:558–560.
   Google Scholar
• Okazaki, K., N. Okazaki, S. Kume, S. Jinno, K. Tanaka, and H. Okayama. 1990. High-frequency transformation method and library transducing vectors for cloning mammalian cDNAs by trans-complementation in Schizosaccharomyces pombe. Nucleic Acids Res. 18:6485.
   PubMed Web of Science ®Google Scholar
• Parada, L. R., H. Land, R. A. Weinberg, D. Wolf, and V. Rotter. 1984. Cooperation between genes encoding p53 tumour antigen and ras in cellular transformation. Nature (London) 312:649–651.
   PubMed Web of Science ®Google Scholar
• Raycroft, L., H. Wu, and G. Lozano. 1990. Transcriptional activation by wild-type but not transforming mutants of the p53 anti-oncogene. Science 249:1049–1051.
   PubMed Web of Science ®Google Scholar
• Rovinski, B., and S. Benchimol. 1988. Immortalization of rat embryo fibroblasts by the cellular p53 oncogene. Oncogene 2:445–452.
   PubMed Web of Science ®Google Scholar
• Samad, A., C. W. Anderson, and R. B. Carrol. 1986. Mapping of phosphomonoester and phosphodiester bonds of the oncogene product p53 from simian virus 40-transformed 3T3 cells. Proc. Natl. Acad. Sci. USA 83:897–901.
   PubMedGoogle Scholar
• Sarnow, P., Y. S. Ho, J. Williams, and A. J. Levine. 1982. Adenovirus Elb-58kd tumor antigen and SV40 large tumor antigen are physically associated with the same 54 kd cellular protein in transformed cells. Cell 28:387.
   PubMed Web of Science ®Google Scholar
• Sommercorn, J., J. A. Mulligan, F. J. Lozeman, and E. G. Krebs. 1987. Activation of casein kinase II in response to insulin and epidermal growth factor. Proc. Natl. Acad. Sci. USA 84:8834–8838.
   PubMed Web of Science ®Google Scholar
• Werness, B. A., A. J. Levine, and P. Μ. Howley. 1990. Association of human papilloma virus types 16 and 18 E6 proteins with p53. Science 248:76–79.
   PubMed Web of Science ®Google Scholar