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Transcriptional Regulation

Transcriptional Activation of the CEF-4/9E3 Cytokine Gene by pp60v-src

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Pages 1490-1499 | Received 23 Oct 1991, Accepted 11 Jan 1992, Published online: 31 Mar 2023

REFERENCES

  • Adkins, B., A. Leutz, and T. Graf. 1984. Autocrine growth induced by src-related oncogenes in transformed chicken myeloid cells. Cell 39:439–445.
  • Almendral, J. Μ., D. Sommer, H. Macdonald-Bravo, J. Burckhardt, J. Perera, and R. Bravo. 1988. Complexity of the early genetic response to growth factors in mouse fibroblasts. Mol. Cell. Biol. 8:2140–2148.
  • Anisowicz, A., L. Bardwell, and R. Sager. 1987. Constitutive overexpression of a growth-regulated gene in transformed Chinese hamster and human cells. Proc. Natl. Acad. Sci. USA 84:7188–7192.
  • Anzano, Μ. A., A. B. Roberts, J. Μ. Smith, Μ. B. Sporn, and J. E. DeLarco. 1983. Sarcoma growth factor from conditioned medium of virally transformed cells is composed of both type α and type β transforming growth factors. Proc. Natl. Acad. Sci. USA 80:6264–6268.
  • Baichwal, V., A. Park, and R. Tjian. 1991. v-Src and EJ Ras alleviate repression of c-jun by a cell-specific inhibitor. Nature (London) 352:165–168.
  • Barker, K., A. Aderem, and H. Hanafusa. 1989. Modulation of arachidonic acid metabolism by Rous sarcoma virus. J. Virol. 63:2929–2935.
  • Barker, K., and H. Hanafusa. 1990. Expression of 9E3 mRNA is associated with mitogenicity, phosphorylation, and morphological alteration in chicken embryo fibroblasts. Mol. Cell. Biol. 10:3813–3817.
  • Bédard, P.-A., D. Alcorta, D. L. Simmons, K.-C. Luk, and R. L. Erikson. 1987. Constitutive expression of a gene encoding a polypeptide homologous to biologically active human platelet protein in Rous sarcoma virus-transformed fibroblasts. Proc. Natl. Acad. Sci. USA 84:6715–6719.
  • Bell, S. Μ., R. W. Brackenbury, N. D. Leslie, and J. L. Degen. 1990. Plasminogen activator gene expression is induced by the src oncogene product and tumor promoters. J. Biol. Chem. 265:1333–1338.
  • Binétruy, B., T. Smeal, and Μ. Karin. 1991. Ha-ras augments c-Jun activity and stimulates phosphorylation of its activation domain. Nature (London) 351:122–127.
  • Birchenall-Roberts, Μ. C., F. Ruscetti, J. Kasper, H.-D. Lee, R. Friedman, A. Geiser, Μ. B. Sporn, A. B. Roberts, and S.-J. Kim. 1990. Transcriptional regulation of the transforming growth factor βl promoter by v-src gene products is mediated through the AP-1 complex. Mol. Cell. Biol. 10:4978–4983.
  • Birnbaum, Μ. J., H. C. Haspel, and O. Μ. Rosen. 1987. Transformation of rat fibroblasts by FSV rapidly increases glucose transporter gene transcription. Science 235:1495–1498.
  • Blobel, G. A., and H. Hanafusa. 1991. The v-src inducible gene 9E3/pCEF-4 is regulated by both its promoter upstream sequence and its 3′ untranslated region. Proc. Natl. Acad. Sci. USA 88:1162–1166.
  • Bohman, D., A. Admon, D. R. Turner, and R. Tjian. 1989. Transcriptional regulation by the AP-1 family of enhancer binding proteins: a nuclear target for signal transduction. Cold Spring Harbor Symp. Quant. Biol. 53:695–700.
  • Bowen-Pope, D. F., A. Vogel, and R. Ross. 1984. Production of platelet-derived growth factor-like molecules and reduced expression of platelet-derived growth factor receptors accompany transformation by a wide spectrum of agents. Proc. Natl. Acad. Sci. USA 81:2396–2400.
  • Boyle, W. J., T. Smeal, L. H. K. Defize, P. Angel, J. R. Woodgett, Μ. Karin, and T. Hunter. 1991. Activation of protein kinase C decreases phosphorylation of c-jun at sites that negatively regulate its DNA-binding activity. Cell 64:573–584.
  • Caput, D., B. Beutler, K. Hartog, R. Thayer, S. Brown-Shimer, and A. Cerami. 1986. Identification of a common nucleotide sequence in the 3′ untranslated region of mRNA molecules specifying inflammatory mediators. Proc. Natl. Acad. Sci. USA 83:1670–1674.
  • Cochran, B. H., A. C. Reffel, and C. D. Stiles. 1983. Molecular cloning of gene sequences regulated by platelet-derived growth factor. Cell 33:939–947.
  • Dignam, J. D., R. Μ. Lebovitz, and R. G. Roeder. 1983. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res. 11:1475–1489.
  • Dodgson, J. B., J. Strommer, and J. D. Engel. 1979. Isolation of the chicken β-like globin gene from a chicken DNA recombinant library. Cell 17:879–887.
  • Dutta, A., Μ. Hamaguchi, and H. Hanafusa. 1990. Serum independence of transcription from the promoter of an avian retrovirus in v-src-transformed cells is a primary, intracellular effect of increased tyrosine phosphorylation. Proc. Natl. Acad. Sci. USA 87:608–612.
  • Dutta, A., Μ. Y. Stoeckle, and H. Hanafusa. 1990. Serum and v-src increase the level of a CCAAT-binding factor required for transcription from a retroviral long terminal repeat. Genes Dev. 4:243–254.
  • Edlund, T., Μ. D. Walker, P. J. Barr, and W. J. Rutter. 1985. Cell-specific expression of the rat insulin gene: evidence for role of two distinct 5′ flanking elements. Science 230:912–916.
  • Flier, J. S., Μ. Μ. Mueckler, P. Usher, and H. F. Lodish. 1987. Elevated levels of glucose transport and transporter messenger RNA are induced by ras or src oncogenes. Science 235:1492–1495.
  • Fromental, C., Μ. Kanno, H. Nomiyama, and P. Chambon. 1988. Cooperativity and hierarchical levels of functional organization in the SV40 enhancer. Cell 54:943–953.
  • Fuji, Μ., D. Shalloway, and I. Μ. Verma. 1989. Gene regulation by tyrosine kinases: src protein activates various promoters, including c-fos. Mol. Cell. Biol. 9:2493–2499.
  • Gauthier-Rouvière, C., A. Fernandez, and N. J. C. Lamb. 1990. ras-induced c-fos expression and proliferation in living rat fibroblasts involves C-kinase activation and the serum response element pathway. EMBO J. 9:171–180.
  • Gonneville, L., T. J. Martins, and P.-A. Bédard. 1991. Complex expression pattern of the CEF-4 cytokine in transformed and mitogenically stimulated cells. Oncogene 6:1825–1833.
  • Goodbourn, S., and T. Maniatis. 1988. Overlapping positive and negative regulatory domains of the human β-interferon gene. Proc. Natl. Acad. Sci. USA 85:1447–1451.
  • Greenberg, Μ. E., and E. B. Ziff. 1984. Stimulation of 3T3 cells induces transcription of c-fos protooncogene. Nature (London) 311:433–437.
  • Gutman, A., and B. Wasylyk. 1990. The collagenase gene promoter contains a TPA and oncogene-responsive unit encompassing the PEA3 and AP-1 binding sites. EMBO J. 9:2241–2246.
  • Gutman, A., and B. Wasylyk. 1991. Nuclear targets for transcription regulation by oncogenes. Trends Genet. 7:49–54.
  • Gutman, A., C. Wasylyk, and B. Wasylyk. 1991. Cell-specific regulation of oncogene-responsive sequences of the c-fos promoter. Mol. Cell. Biol. 11:5381–5387.
  • Hérault, Y., G. Chatelain, G. Brun, and D. Michel. Submitted for publication.
  • Jähner, D., and T. Hunter. 1991. The stimulation of quiescent rat fibroblasts by v-src and v-fps oncogenic protein-tyrosine kinases leads to the induction of a subset of immediate early genes. Oncogene 6:1259–1268.
  • Jähner, D., and T. Hunter. 1991. The ras-related gene rhoB is an immediate-early gene inducible by v-fps, epidermal growth factor, and platelet-derived growth factor in rat fibroblasts. Mol. Cell. Biol. 11:3682–3690.
  • Jamal, S., and E. Ziff. 1990. Transactivation of c-fos and β-actin genes by raf as a step in early response to transmembrane signals. Nature (London) 344:463–466.
  • Kowalski, J., and D. T. Denhardt. 1989. Regulation of the mRNA for monocyte-derived neutrophil-activating peptide in differentiating HL60 promyelocytes. Mol. Cell. Biol. 9:1946–1957.
  • Lau, L. F., and D. Nathans. 1987. Expression of a set of growth-related immediate early genes in BALB/c 3T3 cells: coordinate regulation with c-fos or c-myc. Proc. Natl. Acad. Sci. USA 84:1182–1186.
  • Lenardo, Μ. J., C.-M. Fan, T. Maniatis, and D. Baltimore. 1989. The involvement of NF-κΒ in β-interferon gene regulation reveals its role as widely inducible mediator of signal transduction. Cell 57:287–294.
  • Lloyd, A., N. Yancheva, and B. Wasylyk. 1991. Transformation suppressor activity of a Jun transcription factor lacking its activation domain. Nature (London) 352:635–638.
  • Lopata, Μ. A., D. W. Cleveland, and B. Sollner-Webb. 1984. High level transient expression of a chloramphenicol acetyl transferase gene by DEAE-dextran mediated DNA transfection coupled with a dimethyl sulfoxide or glycerol shock treatment. Nucleic Acids Res. 12:5707–5717.
  • Matrisian, L. Μ., G. T. Bowden, P. Krieg, G. Fürstenberger, J.-P. Briand, P. Leroy, and R. Breathnach. 1986. The mRNA coding for the secreted protease transin is expressed more abundantly in malignant than in benign tumors. Proc. Natl. Acad. Sci. USA 83:9413–9417.
  • Matrisian, L. Μ., N. Glaichenhaus, M.-C. Gesnel, and R. Breathnach. 1985. Epidermal growth factor and oncogenes induce transcription of the same cellular mRNA in rat fibroblasts. EMBO J. 4:1435–1440.
  • McKnight, S., and R. Tjian. 1986. Transcriptional selectivity of viral genes in mammalian cells. Cell 46:795–805.
  • Piette, J., S.-I. Hirai, and Μ. Yaniv. 1988. Constitutive synthesis of activator protein 1 transcription factor after viral transformation of mouse fibroblasts. Proc. Natl. Acad. Sci. USA 85:3401–3405.
  • Qureshi, S. A., X. Cao, V. P. Sukhatme, and D. A. Foster. 1991. v-Src activates mitogen-responsive transcription factor Egr-1 via serum response elements. J. Biol. Chem. 266:10802–10806.
  • Qureshi, S. A., C. K. Joseph, Μ. Rim, A. Maroney, and D. A. Foster. 1991. v-Src activates both protein kinase C-dependent and independent signalling pathways in murine fibroblasts. Oncogene 6:995–999.
  • Richmond, A., and H. G. Thomas. 1986. Purification of melanoma growth stimulatory activity. J. Cell. Physiol. 129:375–384.
  • Rosenthal, N. 1987. Identification of regulatory elements of cloned genes with functional assays. Methods Enzymol. 152:704–720.
  • Salier, J.-P., and K. Kurachi. 1989. A CAT expression vector with virtually no background: pUMSVOCAT. Biotechniques 7:30–31.
  • Schönthal, A., P. Herrlich, H. J. Rahmsdorf, and H. Ponta. 1988. Requirement for fos gene expression in the transcriptional activation of collagenase by other oncogenes and phorbol esters. Cell 54:325–334.
  • Shaw, G., and R. Kamen. 1986. A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation. Cell 46:659–667.
  • Smeal, T., B. Binetruy, D. A. Mercola, Μ. Birrer, and Μ. Karin. 1991. Oncogenic and transcriptional cooperation with Ha-ras requires phosphorylation of c-Jun on serines 63 and 73. Nature (London) 354:494–496.
  • Sprangler, R., C. Joseph, S. A. Qureshi, K. L. Berg, and D. A. Foster. 1989. Evidence that v-src and v-fps use a protein kinase C-mediated pathway to induce expression of a transformation- related gene. Proc. Natl. Acad. Sci. USA 86:7017–7021.
  • Stoeckle, Μ., S. Sugano, A. Hampe, A. Vashistha, D. Pellman, and H. Hanafusa. 1988. 78-Kilodalton glucose-regulated protein is induced in Rous sarcoma virus-transformed cells independently of glucose deprivation. Mol. Cell. Biol. 8:2675–2680.
  • Stoeckle, Μ. Y., and K. A. Barker. 1990. Two burgeoning families of platelet factor 4-related proteins: mediators of the inflammatory response. New Biol. 2:313–323.
  • Stoeckle, Μ. Y., and H. Hanafusa. 1989. Processing of 9E3 mRNA and regulation of its stability in normal and Rous sarcoma virus-transformed cells. Mol. Cell. Biol. 9:4738–4745.
  • Sugano, S., Μ. Y. Stoeckle, and H. Hanafusa. 1987. Transformation by Rous sarcoma virus induces a novel gene with homology to a mitogenic platelet protein. Cell 49:321–328.
  • Taylor, J. W., J. Ott, and F. Eckstein. 1985. The rapid generation of oligonucleotide-directed mutations at high frequency using phosphorothioate-modified DNA. Nucleic Acids Res. 13:8765–8785.
  • Wasylyk, C., A. Gutman, R. Nicholson, and B. Wasylyk. 1991. The c-Ets oncoprotein activates the stromelysin promoter through the same elements as several non-nuclear oncoproteins. EMBO J. 10:1127–1134.
  • Wasylyk, C., J. L. Imler, and B. Wasylyk. 1988. Transforming but not immortalizing oncogenes activate the transcription factor PEA1. EMBO J. 7:2475–2483.
  • Welham, Μ. J., J. A. Wyke, A. Lang, and A. W. Wyke. 1990. Mitogenesis induced by pp60v-src is not accompanied by increased expression of immediate early response genes. Oncogene 5:161–169.
  • White, Μ. K., T. B. Rall, and Μ. J. Weber. 1991. Differential regulation of glucose transporter isoforms by the src oncogene in chicken embryo fibroblasts. Mol. Cell. Biol. 11:4448–4454.
  • Wood, T. G., Μ. L. McGeady, B. Μ. Baroudy, D. G. Blair, and G. F. Van de Woude. 1984. Mouse c-mos oncogene activation is presented by upstream sequences. Proc. Natl. Acad. Sci. USA 81:7817–7821.
  • Yamamura, Y., T. Hattori, K. Obaru, K. Sakai, N. Asou, K. Takatsuki, Y. Ohmoto, H. Nomiyama, and K. Shimada. 1989. Synthesis of a novel cytokine and its gene (LD78) expressions in haematopoietic fresh tumor cells and cell lines. J. Clin. Invest. 84:1707–1712.
  • Zipfel, P. F., J. Balke, S. G. Irving, K. Kelly, and U. Siebenlist. 1989. Mitogenic activation of human T cells induces two closely related genes which share structural similarities with a new family of secreted factors. J. Immunol. 142:1582–1590.

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