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Cell Growth and Development

Deregulated c-myb Disrupts Interleukin-6- or Leukemia Inhibitory Factor-Induced Myeloid Differentiation Prior to c-myc: Role in Leukemogenesis

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Pages 2493-2500 | Received 09 Jan 1992, Accepted 05 Mar 1992, Published online: 31 Mar 2023

References

  • Abdollahi, Α., Κ. A. Lord, Β. Hoffman-Liebermann, and D. A. Liebermann. 1991. Interferon regulatory factor-1 is a myeloid differentiation primary response gene induced by interleukin 6 and leukemia inhibitory factor: role in growth inhibition. Cell Growth Differ. 2:401–407.
  • Bading, H., J. Hansen, and K. Moelling. 1987. Selective DNA binding of the human cellular myb protein isolated by immunoaffinity chromatography using a monoclonal antibody. Oncogene 1:395–401.
  • Beaumont, C., I. Dugat, F. Renaudie, M. Souroujon, and B. Grandchamp. 1989. Transcriptional regulation of ferritin Η and L subunits in adult erythroid and liver cells from the mouse. J. Biol. Chem. 264:7498–7504.
  • Bender, T. P., C. B. Thompson, and W. M. Kuehl. 1987. Differential expression of c-myb in RNA in murine Β lymphomas by blocked transcription elongation. Science 237:1473–1476.
  • Chomczynski, P., and N. Sacchi. 1987. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:156–159.
  • Chou, C., R. A. Gatti, M. L. Fuller, P. Concannon, A. Wong, S. Chada, R. David, and W. A. Salser. 1986. Structure and expression of ferritin genes in a human promyelocytic cell line that differentiated in vitro. Mol. Cell. Biol. 6:566–573.
  • Clarke, M. F., J. F. Kukowska-Latallo, E. Westin, M. Smith, and E. V. Prochownik. 1988. Constitutive expression of a c-myb cDNA blocks Friend murine erythroleukemia cell differentiation. Mol. Cell. Biol. 8:884–892.
  • Evans, J. L., T. L. Moore, W. M. Kuehl, T. Bender, and J. P.-Y. Ting. 1990. Functional analysis of c-Myb protein in alymphocytic cell lines shows that it trans-activates the c-myc promoter. Mol. Cell. Biol. 10:5747–5752.
  • Feinberg, A. P., and B. Vogelstein. 1983. A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal. Biochem. 132:6–13.
  • Fibach, E., and L. Sachs. 1975. Control of normal differentiation of myeloid leukemic cells. VIII. Induction of differentiation to mature granulocytes in mass culture. J. Cell. Physiol. 86:221–230.
  • Gabrielsen, O. S., A. Sentenac, and P. Fromageot. 1991. Specific DNA binding by c-myb; evidence for a double helix-turn-helix-related motif. Science 253:1140–1143.
  • Gonda, T. J., N. M. Gough, A. R. Dunn, and J. de Blaquiere. 1985. The nucleotide sequence of cDNA clones of the murine myb proto-oncogene. EMBO J. 6:3995–4002.
  • Gonda, T. J., D. K. Sheiness, and J. M. Bishop. 1982. Transcripts from the cellular homologs of retroviral oncogenes: distribution among chicken tissues. Mol. Cell. Biol. 2:617–624.
  • Gough, N. Personal communication.
  • Hoffman-Liebermann, B., and D. A. Liebermann. 1991. Inter-leukin-6- and leukemia inhibitory factor-induced terminal differentiation of myeloid leukemia cells is blocked at an intermediate stage by constitutive c-myc. Mol. Cell. Biol. 11:2375–2381.
  • Hoffman-Liebermann, B., and D. A. Liebermann. 1991. Suppression of c-myc and c-myb is tightly linked to terminal differentiation induced by IL6 or LIF and not growth inhibition in myeloid leukemia cells. Oncogene 6:903–909.
  • Horak, H., A. R. Turner, and O. W. Yau. 1982. Comparison of colony stimulating activities secreted into mouse lung conditioned medium in the presence and absence of lithium chloride. Exp. Hematol. 10:123–129.
  • Krystosek, Α., and L. Sachs. 1976. Control of lysozyme induction in the differentiation of myeloid leukemic cells. Cell 9:675–684.
  • Kuehl, W. M., T. P. Bender, J. Stafford, D. McClinton, S. Segal, and E. Dmitrovsky. 1988. Expression and function of the c-myb oncogene during hematopoietic differentiation. Curr. Top. Microbiol. Immunol. 141:318–323.
  • Liebermann, D. Α., and B. Hoffman-Liebermann. 1989. Protooncogene expression and dissection of the myeloid growth to differentiation developmental cascade. Oncogene 4:583–592.
  • Lord, Κ. Α., A. Abdollahi, B. Hoffman-Liebermann, and D. A. Liebermann. 1990. Dissection of the immediate early response of myeloid leukemic cells to terminal differentiation and growth inhibitory stimuli. Cell Growth Differ. 1:637–645.
  • Lord, Κ. Α., A. Abdollahi, S. M. Thomas, M. DeMarco, J. S. Brugge, B. Hoffman-Liebermann, and D. A. Liebermann. 1991. Leukemia inhibitory factor and interleukin-6 trigger the same immediate early response, including tyrosine phosphorylation, upon induction of myeloid leukemia differentiation. Mol. Cell. Biol. 11:4371–4379.
  • Lord, Κ. Α., Β. Hoffman-Liebermann, and D. A. Liebermann. 1990. Complexity of the immediate early response of myeloid cells to terminal differentiation and growth arrest includes ICAM-1, JunB and histone variants. Oncogene 5:387–396.
  • Lord, Κ. Α., Β. Hoffman-Liebermann, and D. A. Liebermann. 1990. Nucleotide sequence and expression of a cDNA encoding MyD88, a novel myeloid differentiation primary response gene induced by IL6. Oncogene 5:1095–1097.
  • Lotem, J., and L. Sachs. 1976. Control of Fc and C3 receptors on myeloid leukemic cells. J. Immunol. 117:580–586.
  • McClinton, D., J. Stafford, L. Brents, T. P. Bender, and W. M. Kuehl. 1990. Differentiation of mouse erythroleukemia cells is blocked by late up-regulation of a c-myb transgene. Mol. Cell. Biol. 10:705–710.
  • Mushinski, J. F., M. Potter, S. R. Bauer, and E. P. Reddy. 1983. DNA rearrangement and altered RNA expression of the c-myb oncogene in mouse plasmacytoid lymphosarcomas. Science 220:795–798.
  • Prochownik, E. V., and J. Kukowska. 1986. Deregulated expression of c-myc by murine erythroleukemia cells prevents differentiation. Nature (London) 322:848–850.
  • Sachs, L. 1987. Cell differentiation and bypassing of genetic defects in the suppression of malignancy. Cancer Res. 47:1981–1986.
  • Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual, 2nd ed., Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
  • Sawyers, C., C. T. Denny, and Ο. Ν. Witte. 1991. Leukemia and the disruption of normal hematopoiesis. Cell 64:337–350.
  • Shabo, Y., J. Lotem, M. Rubinstein, M. Revel, S. C. Clark, S. F. Wolf, R. Kamen, and L. Sachs. 1988. The myeloid blood cell differentiation-inducing protein MGI-2A is interleukin-6. Blood 72:2070–2073.
  • Slamon, D. J., T. C. Boone, D. C. Murdock, D. E. Keith, M. F. Press, R. A. Larson, and L. M. Souza. 1986. Studies of the human c-myb gene and its product in human acute leukemias. Science 233:347–351.

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