Induction of the POU Domain Transcription Factor Oct-2 during T-Cell Activation by Cognate Antigen

References

• Ausubel, F. M., R. Brent, R. E. Kingston, D. D. Moore, J. G. Seidman, J. A. Smith, and K. Struhl. 1987. Current protocols in molecular biology. John Wiley & Sons, Inc., New York.
   Google Scholar
• Banerji, S. S., J. N. Parsons, and M. J. Tocci. 1991. The immunosuppressant FK-506 specifically inhibits mitogen-induced activation of the interleukin-2 promoter and the isolated enhancer elements NFIL-2A and NF-AT1. Mol. Cell. Biol. 11:4074–4087.
   PubMedGoogle Scholar
• Bours, V., J. Villalobos, P. R. Burd, K. Kelly, and U. Siebenlist. 1990. Cloning of a mitogen-inducible gene encoding a kappa Β DNA-binding protein with homology to the rel oncogene and to cell-cycle motifs. Nature (London) 348:76–80.
   PubMed Web of Science ®Google Scholar
• Brabletz, T., I. Pietrowski, and E. Serfling. 1991. The immunosuppressives FK506 and cyclosporin A inhibit the generation of protein factors binding to the two purine boxes of the interleukin 2 enhancer. Nucleic Acids Res. 19:61–67.
   PubMedGoogle Scholar
• Cockerill, P. N., and S. P. Klinken. 1990. Octamer-binding proteins in diverse hemopoietic cells. Mol. Cell. Biol. 10:1293–1296.
   PubMedGoogle Scholar
• Durand, D., J.-P. Shaw, M. R. Bush, R. E. Replogle, R. Belagaje, and G. R. Crabtree. 1988. Characterization of antigen receptor response elements within the interleukin-2 enhancer. Mol. Cell. Biol. 8:1715–1724.
   PubMed Web of Science ®Google Scholar
• Fiering, S., J. P. Northrup, G. P. Nolan, G. R. Crabtree, and L. A. Herzenberg. 1990. Single cell assay of a transcription factor reveals a threshold in transcription activated by signals emanating from the T-cell antigen receptor. Genes Dev. 4:1823–1834.
   PubMed Web of Science ®Google Scholar
• Fujita, T., T. Shibuya, K. Ohashi, K. Yamanishi, and T. Taniguchi. 1986. Regulation of human interleukin-2 gene: functional DNA sequences in the 5′ flanking region for the gene expression in activated Τ lymphocytes. Cell 46:401–407.
   PubMedGoogle Scholar
• Hatzopoulos, A. K., A. S. Stoykova, J. R. Erselius, M. Goulding, T. Neuman, and P. Gruss. 1990. Structure and expression of the mouse Oct-2a and Oct-2b, two differentially spliced products of the same gene. Development 109:349–362.
   PubMed Web of Science ®Google Scholar
• He, X., M. N. Treacy, D. M. Simmons, H. A. Ingraham, L. W. Swanson, and M. G. Rosenfeld. 1989. Expression of a large family of POU-domain regulatory genes in mammalian brain development. Nature (London) 340:35–42.
   PubMed Web of Science ®Google Scholar
• Hecht, T. T., D. L. Longo, and L. A. Matis. 1983. The relationship between immune interferon production and proliferation by antigen-specific Τ cell receptor with its ligands. J. Immunol. 131:1049.
   PubMed Web of Science ®Google Scholar
• Herr, W., R. A. Sturm, R. G. Clerc, L. M. Corcoran, D. Baltimore, P. A. Sharp, H. A. Ingraham, M. G. Rosenfeld, M. Finney, G. Ruvkun, and H. R. Horwitz. 1988. The POU-domain: a large conserved region in the mammalian pit-1, oct-1, oct-2, and Caenorhabditis elegans unc-86 gene products. Genes Dev. 2:1513–1516.
   PubMed Web of Science ®Google Scholar
• Kamps, M. P., L. Corcoran, J. H. LeBowitz, and D. Baltimore. 1990. The promoter of the human interleukin-2 gene contains two octamer-binding sites and is partially activated by the expression of Oct-2. Mol. Cell. Biol. 10:5464–5472.
   PubMedGoogle Scholar
• Kang, S.-M., and M. J. Lenardo. Unpublished data.
   Google Scholar
• Kang, S.-M., A.-C. Tran, and M. J. Lenardo. Unpublished data.
   Google Scholar
• Kemler, I., and W. Schaffner. 1990. Octamer transcription factors and the cell type-specificity of immunoglobulin gene expression. FASEB J. 4:1444–1449.
   PubMedGoogle Scholar
• Mattila, P. S., K. S. Ullman, S. Fiering, E. A. Emmel, M. McCutcheon, G. R. Crabtree, and L. A. Herzenberg. 1990. The actions of cyclosporin A and FK506 suggest a novel step in the activation of Τ lymphocytes. EMBO J. 9:4425–4433.
   PubMedGoogle Scholar
• Ohlsson, H., and T. Edlund. 1986. Sequence-specific interactions of nuclear factors with the insulin gene enhancer. Cell 45:35–44.
   PubMedGoogle Scholar
• Randak, C., T. Brabletz, M. Hergenrother, I. Sobotta, and E. Serfling. 1990. Cyclosporin A suppresses the expression of the interleukin 2 gene by inhibiting the binding of lymphocyte-specific factors to the IL-2 enhancer. EMBO J. 9:2529–2536.
   PubMed Web of Science ®Google Scholar
• Reed, J. C., J. D. Alpers, P. C. Nowell, and R. G. Hoover. 1986. Sequential expression of proto-oncogenes during lectin-stimulated mitogenesis of normal human lymphocytes. Proc. Natl. Acad. Sci. USA 83:3982–3986.
   PubMed Web of Science ®Google Scholar
• Rosner, M. H., M. A. Vigano, K. Ozato, P. M. Timmons, F. Poirier, P. W. J. Rigby, and L. M. Staudt. 1990. A POU-domain transcription factor in early stem cells and germ cells of the mammalian embryo. Nature (London) 345:686–692.
   PubMed Web of Science ®Google Scholar
• Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
   Google Scholar
• Schlissel, M. S., L. M. Corcoran, and D. Baltimore. 1991. Virus-transformed pre-B cells show ordered activation but not inactivation of immunoglobulin gene rearrangement and transcription. J. Exp. Med. 173:711–720.
   PubMedGoogle Scholar
• Schreiber, E., P. Matthias, M. Muller, and W. Schaffner. 1988. Identification of a novel lymphoid specific octamer binding protein (OTF-2B) by proteolytic clipping bandshift assay (PCBA). EMBO J. 7:4221–4229.
   PubMed Web of Science ®Google Scholar
• Shibuya, H., and Τ. Taniguchi. 1989. Identification of multiple cis-elements and trans-acting factors involved in the induced expression of human IL-2 gene. Nucleic Acids Res. 17:9173–9184.
   PubMedGoogle Scholar
• Siebenlist, U., D. B. Durand, P. Bressler, N. J. Holbrook, C. A. Norris, M. Kamoun, J. A. Kant, and G. R. Crabtree. 1986. Promoter region of interleukin-2 gene undergoes chromatin structure changes and confers inducibility on chloramphenicol acetyltransferase gene during activation of Τ cells. Mol. Cell. Biol. 6:3042–3049.
   PubMedGoogle Scholar
• Staudt, L. M., R. G. Clerc, H. Singh, J. H. LeBowitz, P. A. Sharp, and D. Baltimore. 1988. Cloning of a lymphoid-specific cDNA encoding a protein binding the regulatory octamer DNA motif. Science 241:577–580.
   PubMed Web of Science ®Google Scholar
• Staudt, L. M., and M. J. Lenardo. 1991. Immunoglobulin gene transcription. Annu. Rev. Immunol. 9:373–398.
   PubMed Web of Science ®Google Scholar
• Staudt, L. M., H. Singh, S. Sen, T. Wirth, P. A. Sharp, and D. Baltimore. 1986. A lymphoid-specific protein binding to the octamer motif of immunoglobulin genes. Nature (London) 323:640–643.
   PubMed Web of Science ®Google Scholar
• Tanaka, T., S. Z. Ben-Sasson, and W. E. Paul. 1991. IL-4 increases IL-2 production by Τ cells in response to accessory cell-independent stimuli. J. Immunol. 146:3831–3839.
   PubMedGoogle Scholar
• Tendler, C. L., S. J. Greenberg, J. D. Burton, D. Danielpour, S.-J. Kim, W. A. Blattner, A. Manns, and T. A. Waldmann. 1991. Cytokine induction in HTLV-1 associated myelopathy and adult T-cell leukemia: alternate molecular mechanisms underlying retroviral pathogenesis. J. Cell. Biochem. 46:302–311.
   PubMedGoogle Scholar
• Ullman, K. S., M. Flanagan, C. A. Edwards, and G. R. Crabtree. 1991. Activation of early gene expression in T-lymphocytes by Oct-1 and an inducible protein, OAP40. Science 254:558–562.
   PubMedGoogle Scholar
• Ullman, K. S., J. P. Northrop, C. L. Verwelj, and G. R. Crabtree. 1990. Transmission of signals from the Τ lymphocyte antigen receptor to the genes responsible for cell proliferation and immune function: the missing link. Annu. Rev. Immunol. 8:421–452.
   PubMed Web of Science ®Google Scholar
• Wright, J. J., K. C. Gunter, H. Mitsuya, S. G. Irving, K. Kelly, and U. Siebenlist. 1990. Expression of a zinc finger gene in HTLV-I- and HTLV-II-transformed cells. Science 248:588–591.
   PubMed Web of Science ®Google Scholar