7
Views
29
CrossRef citations to date
0
Altmetric
Transcriptional Regulation

Cyclic AMP-Independent ATF Family Members Interact with NF-κB and Function in the Activation of the E-Selectin Promoter in Response to Cytokines

, , , , , , & show all
Pages 7180-7190 | Received 04 Jun 1993, Accepted 23 Aug 1993, Published online: 31 Mar 2023

REFERENCES

  • Ausubel, F. M., R. Brent, R. E. Kingston, D. D. Moore, J. G. Seidman, J. A. Smith, and K. Struhl. 1989. Current protocols in molecular biology. Wiley, New York.
  • Baeuerle, P. A. 1991. The inducible transcriptional activator NFκB: regulation by distinct protein subunits. Biochim. Biophys. Acta 1072:63–80.
  • Baeuerle, P. A., and D. Baltimore. 1988. Activation of DNAbinding activity in an apparently cytoplasmic precursor of the NFKB transcription factor. Cell 53:211–217.
  • Baeuerle, P. A., and D. Baltimore. 1988. IKB: a specific inhibitor of the NFKB transcription factor. Science 242:540–546.
  • Bengal, E., L. Ransone, R. Scharfmann, V. J. Dwarld, S. J. Tapscott, H. Weintraub, and I. M. Verma. 1992. Functional antagonism between c-jun and MyoD proteins: a direct physical association. Cell 68:507–519.
  • Bevilacqua, M., E. Butcher, B. Furie, M. Gallatin, M. Gimbrone, J. Harlan, K. Kishimoto, L. Lasky, R. McEver, J. Paulson, S. Rosen, B. Seed, M. Siegelman, T. Springer, L. Stoolman, T. Tedder, A. Varki, D. Wagner, I. Weissman, and G. Zimmerman. 1991. Selectins: a family of adhesion receptors. Cell 67:233.
  • Bevilacqua, M. P., S. Stengelin, M. A. Gimbrone, and B. Seed. 1989. Endothelial leukocyte adhesion molecule 1: an inducibile receptor for neutrophils related to complement regulatory proteins and lectins. Science 243:1160–1165.
  • Blank, V., P. Kourilsky, and A. Israel. 1992. NFKB and related proteins: Rel/dorsal homologies meet ankyrin-like repeats. Trends Biochem. Sci. 17:135–140.
  • Bohnlein, E., J. W. Lowenthal, M. Siekevitz, D. W. Ballard, B. R. Franza, and W. C. Greene. 1988. The same inducible nuclear proteins regulates mitogen activation of both the interleukin-2 receptor-alpha gene and type 1 HIV. Cell 53:827–836.
  • Brasier, A. R., D. Ron, J. E. Tate, and J. F. Habener. 1990. A family of constitutive C/EBP-like DNA binding proteins attenuate the IL-1α induced, NFκB mediated trans-activation of the angiotensinogen gene acute-phase response element. EMBO J. 9:3933–3944.
  • Chatton, B., J. L. Bocco, M. Gaire, C. Hauss, B. Reimund, J. Goetz, and C. Kedinger. 1993. Transcriptional activation by the adenovirus larger Ela product is mediated by members of the cellular transcription factor ATF family which can directly associate with Ela. Mol. Cell. Biol. 13:561–570.
  • Collins, T., A. Williams, G. I. Johnston, J. Kim, R. Eddy, T. Shows, M. A. Gimbrone, and M. P. Bevilacqua. 1991. Structural and chromosomal location of the gene for endothelial-leukocyte adhesion molecule 1. J. Biol. Chem. 266:2466–2473.
  • Cullen, B. R. 1987. Use of eukaryotic expression technology in the functional analysis of cloned genes. Methods Enzymol. 152:684–704.
  • Dignam, J. D., R. M. Lebovitz, and R. G. Roeder. 1983. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res. 11:1475–1489.
  • Dorn, A., C. Benoist, and D. Mathis. 1989. New B-lymphocytespecific enhancer-binding protein. Mol. Cell. Biol. 9:312–320.
  • Du, W., and T. Maniatis. 1992. An ATF/CREB binding site protein is required for virus induction of the human interferon β gene. Proc. Natl. Acad. Sci. USA 89:2150–2154.
  • Flint, K. J., and N. C. Jones. 1991. Differential regulation of three members of the ATF/CREB family of DNA-binding proteins. Oncogene 6:2019–2026.
  • Freimuth, W. W., J. M. Depper, and G. J. Nabel. 1989. Regulation of the IL-2 receptor α-gene. Interaction of a KB binding protein with cell-specific transcription factors. J. Immunol. 143:3064–3068.
  • Gaire, M., B. Chatton, and C. Kedinger. 1990. Isolation and characterization of two novel, closely related ATF cDNA clones from HeLa cells. Nucleic Acids Res. 18:3467–3473.
  • Georgopoulos, K., B. A. Morgan, and D. D. Moore. 1992. Functionally distinct isoforms of the CRE-BP DNA-binding protein mediate activity of a T-cell-specific enhancer. Mol. Cell. Biol. 12:747–757.
  • Ghersa,, P. Unpublished observation.
  • Ghersa, P., R. Hooft van Huijsduijnen, J. Whelan, and J. F. DeLamarter. 1992. Labile proteins play a dual role in the control of endothelial leukocyte adhesion molecule-1 (ELAM-1) gene regulation. J. Biol. Chem. 267:19226–19232.
  • Ghosh, S., and D. Baltimore. 1990. Activation in vitro of NFκB by phosphorylation of its inhibitor IκB. Nature (London) 344:678–682.
  • Gilmore, T. D. 1990. NFκB, KBF1, dorsal, and related matters. Cell 62:841–843.
  • Gonzalez, G. A., K. K. Yamamoto, W. H. Fisher, K. Karr, P. Menzel, W. Briggs, W. W. Vale, and M. R. Montminy. 1989. A cluster of phosphorylation sites on the cyclic-AMP regulated nuclear factor CREB predicted by its sequence. Nature (London) 337:749–752.
  • Gorman, C. M., L. F. Moffat, and B. H. Howard. 1982. Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells. Mol. Cell. Biol. 2:1044–1051.
  • Green, S., I. Issemann, and E. Sheer. 1988. A versatile in vivo eukaryotic expression vector for protein engineering. Nucleic Acids Res. 16:369.
  • Habener, J. F. 1990. Cyclic AMP response element binding proteins: a cornucopia of transcription factors. Mol. Endocrinol. 4:1087–1094.
  • Hai, T., and B. P. C. Chen. Unpublished results.
  • Hai, T., and T. Curran. 1991. Cross-family dimerization of transcription factors Fos/Jun and ATF/CREB alters DNA binding specificity. Proc. Natl. Acad. Sci. USA 88:3720–3724.
  • Hai, T., F. Liu, W. J. Coukos, and M. R. Green. 1989. Transcription factor ATF cDNA clones: an extensive family of leucine zipper proteins able to selectively form DNA-binding heterodimers. Genes Dev. 3:2083–2090.
  • Hoeffier, J. P., P. J. Deutsch, J. Un, and J. F. Habener. 1989. Distinct adenosine 3',5' monophosphate and phorbol esterresponsive signal transduction pathways converge at the level of transcriptional activation by the interactions of DNA-binding proteins. Mol. Endocrinol. 3:868–880.
  • Hooft van Hujsduinen, R., J. Whelan, R. Pescini, A. Beckerandre, A. M. Schenk, and J. F. DeLamarter. 1992. A T-cell enhancer cooperates with NFκB to yield cytokine induction of E-selectin gene transcription in endothelial cells. J. Biol. Chem. 267:22385–22391.
  • Hurst, H. C., N. F. Totty, and N. C. Jones. 1991. Identification and functional characterisation of the cellular activating factor 43 (ATF-43) protein. Nucleic Acids Res. 19:4601–4609.
  • lademarco, M. F., J. J. McQuillan, G. D. Rosen, and D. C. Dean. 1992. Characterization of the promoter for vascular cell adhesion molecule-1 (VCAM-1). J. Biol. Chem. 267:16323–16329.
  • Kieran, M., V. Blank, F. Logeat, J. Vandekerckhove, F. Lottspeich, O. LeBail, M. Urban, P. Kourilsky, P. A. Baeuerle, and A. Israel. 1990. The DNA binding subunit of NFκB is identical to factor KBF1 and homologous to the rel oncogene product. Cell 62:1007–1018.
  • Lasky, L. A. 1992. Selectins: interpreters of cell-specific carbohydrate information during inflammation. Science 258:964–969.
  • LeClair, K. P., M. A. Blanar, and P. A. Sharp. 1992. The p50 subunit of NF-κB associates with the NF-IL6 transcription factor. Proc. Natl. Acad. Sci. USA 89:8145–8149.
  • Lenardo, M. J., and D. Baltimore. 1989. NFκB: a pleiotropic mediator of inducible and tissue-specific gene control. Cell 58:227–229.
  • Li, X., and S. L. Liao. 1991. Expression of rat serum amyloid Al gene involves both C/EBP-like and NFFκB-like transcription factors. J. Biol. Chem. 266:15192–15201.
  • Liu, F., and M. R. Green. 1990. A specific member of the ATF transcription factor family can mediate transcription activation by the adenovirus Ela protein. Cell 61:1217–1224.
  • Maekawa, T., H. Sakura, S. Kanei-Ishii, T. Sudo, T. Yoshimura, J. Fujisawa, M. Yoshida, and S. Ishii. 1989. Leucine zipper structure of the protein CRE-BPl binding to the cAMP response element in brain. EMBO J. 8:2023–2028.
  • Matthews, J. R., N. Wakasugi, J. Virelizier, J. Yodoi, and R. T. Hay. 1992. Thioredoxin regulates the DNA binding activity of NFκB by reduction of a disulphide bond involving cysteine 62. Nucleic Acids Res. 20:3821–3830.
  • Montgomery, K. F., L. Osborn, C. Hession, R. Tizard, D. Goff, C. Vassallo, P. I. Tarr, K. Bomztyk, R. Lobb, J. M. Harlan, and T. H. Pohlman. 1991. Activation of endothelial-leukocyte adhesion molecule 1 (ELAM-1) gene transcription. Proc. Natl. Acad. Sci. USA 88:6523–6527.
  • Mukaida, N., Y. Mahe, and K. Matsushima. 1990. Cooperative interaction of nuclear factor-κB and cis-regulatory enhancer binding protein-like factor binding elements in activating the interleukin-8 gene by pro-inflammatory cytokines. J. Biol. Chem. 265:21128–21133.
  • Osborn, L., C. Hession, R. Tizard, C. Vassallo, S. Luhowskyj, G. Chi-Rosso, and R. Lobb. 1989. Direct expression cloning of vascular cell adhesion molecule 1, a cytokine-induced endothelial protein that binds to lymphocytes. Cell 59:1203–1211.
  • Osborn, L., S. Kunkel, and G. Nabel. 1989. Tumor necrosis factor α and interleukin 1 stimulate the human immunodeficiency virus enhancer by activation of the nuclear factor KB. Proc. Natl. Acad. Sci. USA 86:2336–2340.
  • Pescini, P., W. Kaszubska, J. Whelan, J. F. DeLamarter, and R. Hooft van Huisduinen. ATF-aO is a novel ATF-a variant that forms a dominant transcription inhibitor in ATF-a heterodimers. J. Biol. Chem., in press.
  • Rehfuss, R. P., K. M. Walton, M. M. Loriaux, and R. H. Goodman. 1991. The cAMP-regulated enhancer-binding protein ATF-1 activates transcription in response to cAMP-dependent protein kinase A. J. Biol. Chem. 266:18431–18434.
  • Ruben, S. M., R. Narayanan, J. F. Klement, C. Chien-hwa, and C. A. Rosen. 1992. Functional characterization of the NF-κB p65 transcriptional activator and an alternatively spliced derivative. Mol. Cell. Biol. 12:444–454.
  • Sambrook, J., T. Maniatis, and E. F. Fritsch. 1989. Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
  • Singh, H., H. LeBowitz, A. S. Baldwin, and P. A. Sharp. 1988. Molecular cloning of an enhancer binding protein: isolation by screening an expression library with a recognition site DNA. Cell 52:415–423.
  • Smith, G. M., J. Whelan, R. Pescini, P. Ghersa, J. F. DeLamarter, and R. Hooft van Huijsduinen. 1993. DNA-methylation of the E-selectin promoter represses NFκB transactivation. Biochem. Biophys. Res. Commun. 194:215–221.
  • 51, B., and A. S. Baldwin, Jr. 1993. Distinct mechanisms for regulation of the interleukin-8 gene involve synergism and cooperativity between C/EBP and NF-κB. Mol. Cell. Biol. 13:7191–7198.
  • Stein, B., P. C. Cogswell, and A. S. Baldwin, Jr. 1993. Functional and physical associations between NF-κB and C/EBP family members: a Rel domain-bZIP interaction. Mol. Cell. Biol. 13:3964–3974.
  • Studier, F. W., A. H. Rosenberg, J. J. Dunn, and J. W. Dubendorf. 1990. Use of T7 RNA polymerase to direct the expression of cloned genes. Methods Enzymol. 185:60–89.
  • van Dam, H., M. Duyndam, R. Rottier, A. Bosch, L. de Vries-Smits, P. Herrlich, A. Zantema, P. Angel, and A. J. van der Eb. 1993. Heterodimer formation of cJun and ATF-2 is responsible for induction of c-jun by the 243 amino acid adenovirus ElA protein. EMBO J. 12:479–487.
  • Vinson, C. R., K L. LaMarco, P. F. Johnson, W. H. Landschulz, and S. L. McKnight. 1988. In situ detection of sequence-specific DNA binding activity specified by a recombinant bacteriophage. Genes Dev. 2:801–806.
  • Whelan, J., P. Ghersa, R. Hooft van Hujsduinen, J. Gray, G. Chandra, F. Talabot, and J. F. DeLamarter. 1991. An NFκBlike factor is essential but not sufficient for cytokine induction of endothelial leukocyte adhesion molecule (ELAM) gene transcription. Nucleic Acids Res. 19:2645–2653.
  • Whelan, J., D. Poon, P. A. Weil, and R. Stein. 1989. Pancreatic a-cell-type-specific expression of the rat insulin II gene is controlled by positive and negative cellular transcriptional elements. Mol. Cell. Biol. 9:3253–3259.
  • Ziff, E. B. 1990. Transcription factors: a new family gathers at the cAMP response site. Trends Genet. 6:69–72.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.