1
Views
14
CrossRef citations to date
0
Altmetric
Gene Expression

Sequences Within the Last Intron function in RNA 3'-End Formation in Cultured Cells

, &
Pages 3359-3369 | Received 28 Dec 1992, Accepted 16 Mar 1993, Published online: 01 Apr 2023

REFERENCES

  • Aviv, H., and P. Leder. 1972. Purification of biologically active globin messenger RNA by chromatography on oligothymidylic acid-cellulose. Proc. Natl. Acad. Sci. USA 69:1408–1412.
  • Barrett, N. L., G. G. Carmichael, and Y. Luo. 1991. Splice site requirement for the efficient accumulation of polyoma virus late mRNAs. Nucleic Acids Res. 19:3011–3017.
  • Birnstiel, M. L., M. Busslinger, and K. Strub. 1985. Transcription termination and 3′ processing: the end is in site! Cell 41:349–359.
  • Boyer, T. G., J. R. Krug, and L. E. Maquat. 1989. Transcriptional regulatory sequences of the housekeeping gene for human triosephosphate isomerase. J. Biol. Chem. 264:5177–5187.
  • Brinster, R. L., J. M. Allen, R. R. Behringer, R. E. Gelinas, and R. D. Palmiter. 1988. Introns increase transcriptional efficiency in transgenic mice. Proc. Natl. Acad. Sci. USA 85:836–840.
  • Buchman, A. R., and P. Berg. 1988. Comparison of introndependent and intron-independent gene expression. Mol. Cell. Biol. 8:4395–4405.
  • Callis, J., M. Fromm, and V. Walbot. 1987. Introns increase gene expression in cultured maize cells. Genes Dev. 1:11831200.
  • Chang, D. D., and P. Sharp. 1989. Regulation by HIV rev depends upon recognition of splice sites. Cell 59:789–795.
  • Chen, I.-T., and L. A. Chasin. 1993. Direct selection for mutations affecting specific splice sites in a hamster dihydrofolate reductase minigene. Mol. Cell. Biol. 13:289–300.
  • Cheng, J., M. Fogel-Petrovic, and L. E. Maquat. 1990. Translation to near the distal end of the penultimate exon is required for normal levels of spliced triosephosphate isomerase mRNA. Mol. Cell. Biol. 10:5215–5225.
  • Chiou, H. C., C. Dabrowski, and J. C. Alwine. 1991. Simian virus 40 late mRNA leader sequences involved in augmenting mRNA accumulation via multiple mechanisms, including increased polyadenylation efficiency. J. Virol. 65:6677–6685.
  • Collis, P., M. Antoniou, and F. Grosveld. 1990. Definition of the minimal requirements within the human β-globin gene and the dominant control region for high level expression. EMBO J. 9:233–240.
  • Daar, I. O., and L. E. Maquat. 1988. Premature translation termination mediates triosephosphate isomerase mRNA degra-dation. Mol. Cell. Biol. 8:802–813.
  • Dreyfuss, G., M. S. Swanson, and S. Piñol-Roma. 1988. Heterogeneous nuclear ribonucleoprotein particles and the pathway of mRNA formation. Trends Biochem. 13:86–91.
  • Eckner, R., W. Ellmeier, and M. L. Birnstiel. 1991. Mature mRNA 3′ end formation stimulates RNA export from the nucleus. EMBO J. 10:3513–3522.
  • Fineberg, A. P., and B. Vogelstein. 1983. A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal. Biochem. 132:6–13.
  • Gasser, C. S., C. C. Simonsen, J. W. Schilling, and R. T. Schimke. 1982. Expression of abbreviated mouse dihydrofolate reductase gene in cultured hamster cells. Proc. Natl. Acad. Sci. USA 79:6522–6526.
  • Green, M. R., and M. L. Zapp. 1989. Revving up gene expression. Nature (London) 338:200–201.
  • Gruss, P., and G. Khoury. 1980. Reserve of a splicing defective mutant by insertion of an heterologous intron. Nature 286:634–637.
  • Gruss, P., C.-J. Lai, R. Dhar, and G. Khoury. 1979. Splicing as a requirement for biogenesis of functional 16S mRNA of simian virus 40. Proc. Natl. Acad. Sci. USA 76:4317–4321.
  • Hamer, D. H., K. D. Smith, S. H. Boyer, and P. Leder. 1979. SV40 recombinants carrying rabbit β-globin gene coding se-quences. Cell 17:725–735.
  • Hawkins, J. D. 1988. A survey on intron and exon lengths. Nucleic Acids Res. 16:9893–9908.
  • Huang, M. T.-F., and C. M. Gorman. 1990. Intervening sequences increase efficiency and accumulation of cytoplasmic RNA. Nucleic Acids Res. 18:937–947.
  • Kermekchiev, M., M. Pettersson, P. Matthias, and W. Schaffner. 1991. Every enhancer works with every promoter for all the combinations tested: could new regulatory pathways evolve by enhancer shuffling? Gene Exp. 1:71–81.
  • Kopczynski, C. C., and M. A. T. Muskavitch. 1992. Introns excised from the delta primary transcript are localized near sites of delta transcription. J. Cell Biol. 119:503–512.
  • Kunkel, T. A., J. D. Roberts, and R. A. Zakour. 1987. Rapid and efficient site-specific mutagenesis without phenotype selection. Methods Enzymol. 154:376–382.
  • Lamond, A. I. 1991. Nuclear RNA processing. Curr. Opin. Cell. Biol. 3:493–501.
  • Legrain, P., and M. Rosbash. 1989. Some cis and trans-acting mutants for splicing target pre-mRNA to the cytoplasm. Cell 57:573–583.
  • Maniatis, T. 1991. Mechanisms of alternative pre-mRNA splicing. Science 251:33–34.
  • Maquat, L. E., R. Chilcote, and P. M. Ryan. 1985. Human triosephosphate isomerase cDNA and protein structure: studies of triosephosphate isomerase deficiency in man. J. Biol. Chem. 260:3748–3753.
  • Mason, P. J., J. A. Elkington, M. M. Lloyd, M. B. Jones, and J. G. Williams. 1986. Mutations downstream of the polyadenylation site of a Xenopus β-globin mRNA affect the positions but not the efficiency of 3′ processing. Cell 46:263–270.
  • McKeown, M. 1992. Alternative mRNA splicing. Annu. Rev. Cell Biol. 8:133–155.
  • McMaster, G. K., and G. G. Carmichael. 1977. Analysis of single- and double-stranded nucleic acids on polyacrylamide and agarose gels by using glyoxal and acridine orange. Proc. Natl. Acad. Sci. USA 74:4835–4838.
  • Mitchell, P. J., and R. Tjian. 1989. Transcriptional regulation in mammalian cells by sequence-specific DNA binding proteins. Science 244:371–378.
  • Neuberger, W. S., and G. T. Williams. 1988. The intron requirement for immunoglobulin gene expression is dependent upon the promoter. Nucleic Acids Res. 16:6713–6724.
  • Niwa, M., and S. M. Berget. 1991. Polyadenylation precedes splicing in vitro. Gene Expr. 1:5–14.
  • Niwa, M., and S. M. Berget. 1991. Mutation of the AAUAAA polyadenylation signal depresses in vitro splicing of proximal but not distal introns. Genes Dev. 5:2086–2095.
  • Niwa, M., C. C. MacDonald, and S. M. Berget. 1992. Are vertebrate exons scanned during splice-site selection? Nature (London) 360:277–280.
  • Niwa, M., S. D. Rose, and S. M. Berget. 1990. In vitro polyadenylation is stimulated by the presence of an upstream intron. Genes Dev. 4:1552–1559.
  • Palmiter, R. D., E. P. Sandgren, M. R. Avarbock, D. D. Allen, and R. L. Brinster. 1991. Heterologous introns can enhance expression of transgenes in mice. Proc. Natl. Acad. Sci. USA 88:478–482.
  • Pandey, N. B., N. Chodchoy, T.-J. Liu, and W. F. Marzluff. 1990. Introns in histone genes alter the distribution of 3′ ends. Nucleic Acids Res. 18:3161–3170.
  • Robberson, B. L., G. J. Cote, and S. M. Berget. 1990. Exon definition may facilitate splice site selection in RNAs with multiple exons. Mol. Cell. Biol. 10:84–94.
  • Ryu, W.-S., and J. E. Mertz. 1989. Simian virus 40 late transcripts lacking excisable intervening sequences are defective in both stability in the nucleus and transport to the cytoplasm. J. Virol. 63:4386–4394.
  • Sheets, D. M., C. S. Ogg, and M. P. Wickens. 1990. Point mutations in AAUAAA and the poly(A) addition site effects on the accuracy and efficiency of cleavage and polyadenylation in vitro. Nucleic Acids Res. 18:5799–5805.
  • Smith, C. W. J., J. G. Patton, and B. Nadal-Ginard. 1989. Alternative splicing in the control of gene expression. Annu. Rev. Genet. 23:527–577.
  • Stolow, D. T., and S. M. Berget. 1990. UV cross-linking of polypeptides associated with 3′-terminal exons. Mol. Cell. Biol. 10:5937–5944.
  • Sveren, J., and R. Chalkley. 1990. The structure and assembly of active chromatin. Trends Genet. 6:52–56.
  • Treisman, R., U. Novak, J. Favaloro, and R. Kamen. 1981. Transformation of rat cells by an altered polyoma virus genome expressing only the middle-T protein. Nature (London) 292:595–600.
  • Villarreal, L. P., and R. T. White. 1983. A splice junction deletion deficient in the transport of RNA does not polyadenylate nuclear RNA. Mol. Cell. Biol. 3:1381–1388.
  • Wahle, E., and W. Keller. 1992. The biochemistry of 3′-end cleavage and polyadenylation of messenger RNA precursors. Annu. Rev. Biochem. 61:419–440.
  • Wickens, M. 1990. In the beginning is the end: regulation of poly(A) addition and removal during early development. Trends Biochem. Sci. 15:320–324.
  • Wickens, M. 1990. How the messenger got its tail: addition of poly(A) in the nucleus. Trends Biochem. Sci. 15:277–281.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.