25
Views
33
CrossRef citations to date
0
Altmetric
Cell Growth and Development

The Ribosomal L5 Protein Is Associated with mdm-2 and mdm-2-p53 Complexes

, , , &
Pages 7414-7420 | Received 16 Jun 1994, Accepted 09 Aug 1994, Published online: 30 Mar 2023

References

  • Cahilly-Snyder, L., T. Yang-Feng, U. Francke, and D. L. George. 1987. Molecular analysis and chromosomal mapping of amplified genes isolated from a transformed mouse 3T3 cell line. Somatic Cell Mol. Genet. 13:235–244.
  • Chen, J., V. Marechal, and A. J. Levine. 1993. Mapping of the p53 and mdm-2 interaction domains. Mol. Cell. Biol. 13:4107–4114.
  • Clarke, C. F., K. Cheng, A. B. Frey, R. Stein, P. W. Hinds, and A. J. Levine. 1988. Purification of complexes of nuclear oncogene p53 with rat and Escherichia coli heat shock proteins: in vitro dissociation of hsc70 and dnaK from murine p53 by ATP. Mol. Cell. Biol. 8:1206–1215.
  • Cordon-Cardo, C., E. Latres, M. Drobnjak, M. R. Oliva, D. Pollack, J. M. Woodruff, M. F. Brennan, V. Marechal, J. Chen, and A. J. Levine. 1993. Molecular abnormalities of mdm-2 and p53 genes in adult soft tissue sarcomas. Cancer Res. 54:1–7.
  • Fakharzadeh, S. S., S. P. Trusko, and D. L. George. 1991. Tumorigenic potential associated with enhanced expression of a gene that is amplified in a mouse tumor cell line. EMBO J. 10:1565–1569.
  • Fields, S., and S. K. Jang. 1990. Presence of a potent transcription activating sequence in the p53 protein. Science 249:1046–1049.
  • Finlay, C. A., P. W. Hinds, and A. J. Levine. 1989. The p53 proto-oncogene can act as a suppressor of transformation. Cell 57:1083–1093.
  • Fontoura, B. M. A., E. A. Sorokina, E. David, and R. B. Carroll. 1992. p53 is covalently linked to 5.8S rRNA. Mol. Cell. Biol. 12:5145–5151.
  • Lin, J., J. Chen, B. Elenbaas, and A. J. Levine. 1994. Several hydrophobic amino acids in the p53 N-terminal domain are required for transcriptional activation, binding to mdm-2 and the adenovirus 5 E1B 55kd protein. Genes Dev. 8:1235–1246.
  • Martinez, J., I. Georgoff, J. Martinez, and A. J. Levine. 1991. Cellular localization and cell cycle regulation by a temperature sensitive p53 protein. Genes Dev. 5:151–159.
  • Metspalu, A., I. Toots, M. Saarma, and R. Villems. 1980. The ternary complex consisting of rat liver ribosomal 5S RNA, 5.8S RNA and protein L5. FEBS Lett. 119:81–84.
  • Momand, J., G. P. Zambetti, D. C. Olson, D. George, and A. J. Levine. 1992. The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53 mediated transactivation. Cell 69:1237–1245.
  • Oberosler, P., P. Hloch, U. Ramsperger, and H. Stahl. 1993. P53 catalyzed annealing of complementary single-stranded nucleic acids. EMBO J. 12:2389–2396.
  • Oliner, J. D., K. W. Kinzler, P. S. Meltzer, D. George, and B. Vogelstein. 1992. Amplification of a gene encoding a p53-associated protein in human sarcomas. Nature (London) 358:8083.
  • Olson, D., V. Marechal, J. Momand, J. Chen, C. Romocki, and A. J. Levine. 1993. Identification and characterization of multiple mdm-2 proteins and mdm-2-p53 protein complexes. Oncogene 8:2353–2360.
  • Oren, M., N. C. Reich, and A. J. Levine. 1982. Regulation of the cellular p53 tumor antigen in teratocarcinoma cells and their differentiated progeny. Mol. Cell. Biol. 2:443–449.
  • Raycroft, L., H. Wu, and G. Lozano. 1990. Transcriptional activation by wild-type but not transforming mutants of the p53 antioncogene. Science 249:1049–1051.
  • Samad, A., C. W. Anderson, and R. B. Carroll. 1986. Mapping of phosphomonoester and apparent phosphodiester bonds of the oncogene product p53 from simian virus 40-transformed 3T3 cells. Proc. Natl. Acad. Sci. USA 83:897–901.
  • Samad, A., and R. B. Carroll. 1991. The tumor suppressor p53 is bound to RNA by a stable covalent linkage. Mol. Cell. Biol. 11:1598–1606.
  • Seto, E., A. Usheva, G. P. Zambetti, J. Momand, N. Horikoshi, R. Weinmann, A. J. Levine, and T. Shenk. 1992. Wild-type p53 binds to the TATA-binding protein and represses transcription. Proc. Natl. Acad. Sci. USA 89:12028–12032.
  • Steitz, J. A., C. Berg, J. P. Hendrick, H. La Branch-Chabot, J. Metspalu, J. Rinke, and T. Yario. 1988. A 5S rRNA/L5 complex is a precursor to ribosome assembly in mammalian cells. J. Cell Biol. 106:545–556.
  • Wu, X., J. H. Bayle, D. Olson, and A. J. Levine. 1993. The p53-mdm-2 autoregulatory feedback loop. Genes Dev. 7:1126–1132.
  • Yonish-Rouach, E., D. Resnitzky, J. Lotem, L. Sachs, A. Kimchi, and M. Oren. 1991. Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6. Nature (London) 352:345–347.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.