Regulation of c-jun Expression during Hypoxic and Low-Glucose Stress

References

• Abate, C., D. Luk, and T. Curren. 1990. A ubiquitous nuclear protein stimulates the DNA-binding activity of Fos and Jun indirectly. Cell Growth Differ. 1:455–462.
   PubMedGoogle Scholar
• Abate, C., L. Patel, F. J. Rauscher III, and T. Curran. 1990. Redox regulation of Fos and Jun DNA-binding activity in vitro. Science 249:1157–1161.
   PubMed Web of Science ®Google Scholar
• Adams, G. E., A. Breccia, Ε. M. Fielden, and P. Wardman. 1990. Selective activation of drugs by redox processes. Plenum Press, New York.
   Google Scholar
• Alam, J., and D. Zhining. 1992. Distal AP-1 binding sites mediate basal level enhancement and TPA induction of the mouse heme oxygenase-1 gene. J. Biol. Chem. 267:21894–21900.
   PubMed Web of Science ®Google Scholar
• Anderson, G. R., D. L. Stoler, and L. A. Scarcello. 1989. Normal fibroblasts responding to anoxia exhibit features of the malignant phenotype. J. Biol. Chem. 264:14885–14892.
   PubMed Web of Science ®Google Scholar
• Anderson, G. R., D. L. Stoler, and L. A. Scarcello. 1989. Retro-transposon-like VL30 elements are efficiently induced in anoxic rat fibroblasts. J. Mol. Biol. 205:765–769.
   PubMedGoogle Scholar
• Andrews, N. C., and D. V. Fallen 1991. A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells. Nucleic Acids Res. 19:2499.
   PubMed Web of Science ®Google Scholar
• Angel, P., K. Hattori, T. Smeal, and M. Karin. 1988. The jun proto-oncogene is positively autoregulated by its product, Jun/ AP-1. Cell 55:875–885.
   PubMed Web of Science ®Google Scholar
• Ausubel, F. M., R. Brent, R. E. Kingston, D. D. Moore, J. G. Seidman, J. A. Smith, and K. Struhl. 1990. Current protocols in molecular biology, p. 4.10.1–4.10.9. Wiley Interscience, New York.
   Google Scholar
• Baker, S. J., Τ. Κ. Kerppola, D. Luk, M. Τ. Vanderberg, D. R. Marshak, T. Curran, and C. Abate. 1992. Jun is phosphorylated by several protein kinases at the same sites that are modified in serum-stimulated fibroblasts. Mol. Cell. Biol. 12:4694–4705.
   PubMedGoogle Scholar
• Barber, J. R., and I. M. Verma. 1987. Modification of fos proteins: phosphorylation of c-fos, but not v-/os, is stimulated by 12-tetradecanoyl-phorbol-13-acetate and serum. Mol. Cell. Biol. 7:2201–2211.
   PubMed Web of Science ®Google Scholar
• Binétruy, B., T. Smeal, and M. Karin. 1991. Ha-Ras augments c-Jun activity and stimulates phosphorylation of its activation domain. Nature (London) 351:122–127.
   PubMed Web of Science ®Google Scholar
• Bohmann, D., T. J. Bos, A. Admon, T. Nishimura, P. K. Vogt, and R. Tjian. 1987. Human proto-oncogene c-jun encodes a DNA binding protein with structural and functional properties of transcription factor AP-1. Science 238:1386–1392.
   PubMed Web of Science ®Google Scholar
• Bossy-Wetzel, E., R. Bravo, and D. Hanahan. 1992. Transcription factors JunB and c-Jun are selectively up-regulated and functionally implicated in fibrosarcoma development. Genes Dev. 6:2340–2351.
   PubMedGoogle Scholar
• Boyle, W. J., T. Smeal, L. H. K. Defize, P. Angel, J. R. Woodgett, M. Karin, and T. Hunter. 1991. Activation of protein kinase C decreases phosphorylation of c-Jun at sites that negatively regulate its DNA-binding activity. Cell 64:573–584.
   PubMed Web of Science ®Google Scholar
• Brenner, D. A., M. O'Hara, P. Angel, M. Chojkier, and M. Karin. 1989. Prolonged activation of jun and collagenase genes by tumor necrosis factor-α. Nature (London) 337:661–663.
   PubMed Web of Science ®Google Scholar
• Crawford, D., I. Zbinden, P. Amstad, and P. Cerutti. 1988. Oxidant stress induces the protooncogenes c-fos and c-myc in mouse epidermal cells. Oncogene 3:27–32.
   Web of Science ®Google Scholar
• Devary, Y., R. A. Gottlieb, L. F. Lau, and M. Karin. 1991. Rapid and preferential activation of the c-jun gene during the mammalian UV response. Mol. Cell. Biol. 11:2804–2811.
   PubMed Web of Science ®Google Scholar
• Devary, Y., R. A. Gottlieb, T. Smeal, and M. Karin. 1992. The mammalian ultraviolet response is triggered by activation of src tyrosine kinases. Cell 71:1081–1091.
   PubMed Web of Science ®Google Scholar
• Edwards, D. R., and L. C. Mahadevan. 1992. Protein synthesis inhibitors differentially superinduce c-fos and c-jun by three distinct mechanisms: lack of evidence for labile repressors. EMBO J. 11:2415–2424.
   PubMed Web of Science ®Google Scholar
• Franklin, C. C., V. Sanchez, F. Wagner, J. R. Woodgett, and A. S. Kraft. 1992. Phorbol ester-induced amino-terminal phosphorylation of human Jun but not JunB regulates transcriptional activation. Proc. Natl. Acad. Sci. USA 89:7247–7251.
   PubMedGoogle Scholar
• Gentz, R., F. J. Rauscher, ΙII, C. Abate, and T. Cumin. 1989. Parallel association of Fos and Jun leucine zippers juxtaposes DNA binding domains. Science 243:1695–1699.
   PubMed Web of Science ®Google Scholar
• Giaccia, A. J., E. A. Auger, A. Koong, D. J. Terris, A. I. Minchinton, G. M. Hahn, and J. M. Brown. 1992. Activation of the heat shock transcription factor by hypoxia in normal and tumor cell lines in vivo and in vitro. Int. J. Radiat. Oncol. Biol. Phys. 23:891–897.
   PubMed Web of Science ®Google Scholar
• Hai, T., and T. Curran. 1991. Cross-family dimerization of transcription factors Fos/Jun and ATF/CREB alters DNA binding specificity. Proc. Natl. Acad. Sci. USA 88:3720–3724.
   PubMed Web of Science ®Google Scholar
• Heacock, C. S., and R. M. Sutherland. 1986. Induction characteristics of oxygen regulated proteins. Int. J. Radiat. Oncol. Biol. Phys. 12:1287–1290.
   PubMed Web of Science ®Google Scholar
• Heacock, C. S., and R. M. Sutherland. 1990. Enhanced synthesis of stress proteins caused by hypoxia and relation to altered cell growth and metabolism. Br. J. Cancer 62:217–225.
   PubMedGoogle Scholar
• Kikkawa, U., A. Kishimoto, and Y. Nishizuka. 1989. The protein kinase C family: heterogeneity and its implications. Annu. Rev. Biochem. 58:31–44.
   PubMed Web of Science ®Google Scholar
• Laderoute, K. R., T. D. Grant, B. J. Murphy, and R. M. Sutherland. 1992. Enhanced epidermal growth factor receptor synthesis in human squamous carcinoma cells exposed to low levels of oxygen. Int. J. Cancer 52:428–432.
   PubMed Web of Science ®Google Scholar
• Lamph, W. W., P. Wamsley, P. Sassone-Corsi, and I. M. Verma. 1988. Induction of proto-oncogene JUN/AP-1 by serum and TPA. Nature (London) 334:629–631.
   PubMed Web of Science ®Google Scholar
• Lee, W. F., C. Lin, and T. Curran. 1988. Activation of the transforming potential of the human fos proto-oncogene requires message stabilization and results in increased amounts of partially modified fos protein. Mol. Cell. Biol. 8:5521–5527.
   PubMedGoogle Scholar
• Lin, A., J. Frost, T. Deng, T. Smeal, N. Al-Alawi, U. Kikkawa, T. Hunter, D. Brenner, and M. Karin. 1992. Casein kinase II is a negative regulator of c-Jun DNA binding and AP-1 activity. Cell 70:777–789.
   PubMedGoogle Scholar
• Lowry, C. V., and R. H. Lieber. 1986. Negative regulation of the Saccharomyces cerevisiae ANB1 gene by heme, as mediated by the ROX1 gene product. Mol. Cell. Biol. 6:4145–4148.
   PubMedGoogle Scholar
• Maines, M. D. 1988. Heme oxygenase: function, multiplicity, regulatory mechanisms, and clinical applications. FASEB J. 2:2557–2568.
   PubMed Web of Science ®Google Scholar
• Maki, Y., T. J. Bos, C. Davis, M. Starbuck, and P. K. Vogt. 1987. Avian sarcoma virus 17 carries the jun oncogene. Proc. Natl. Acad. Sci. USA 84:2848–2852.
   PubMed Web of Science ®Google Scholar
• Mehta, K. D., D. Leung, L. Lefebvre, and M. Smith. 1990. The ANB1 locus of Saccharomyces cerevisiae encodes the protein synthesis initiation factor eIF-4D. J. Biol. Chem. 265:8802–8807.
   PubMedGoogle Scholar
• Meister, A. 1991. Glutathione deficiency produced by inhibition of its synthesis, and its reversal; applications in research and therapy. Pharmacol. Ther. 51:155–194.
   PubMed Web of Science ®Google Scholar
• Meyer, M., R. Schreck, and P. A. Baeuerle. 1993. H2O2 and antioxidants have opposite effects on activation of NF-κΒ and AP-1 in intact cells: AP-1 as secondary antioxidant-responsive factor. EMBO J. 12:2005–2015.
   PubMed Web of Science ®Google Scholar
• Murphy, B. J., K. R. Laderoute, S. M. Short, and R. M. Sutherland. 1991. The identification of heme oxygenase as a major hypoxic stress protein in Chinese hamster ovary cells. Br. J. Cancer 64:69–73.
   PubMed Web of Science ®Google Scholar
• O'Conner, J. L., and M. F. Wade. 1992. Determination of coexist- ing nuclear transcription rates and cytoplasmic mRNA levels for gonadotropin subunit genes in rat anterior pituitary. BioTechniques 12:238–243.
   PubMedGoogle Scholar
• Plate, K. H., G. Breier, H. A. Weich, and W. Risau. 1992. Vascular endothelial growth factor is a potential tumour angiogenesis factor in human glioma in vivo. Nature (London) 359:845–848.
   PubMed Web of Science ®Google Scholar
• Price, B. D., and S. K. Calderwood. 1992. gadd45 and gaddl53 messenger RNA levels are increased during hypoxia and after exposure to agents which elevate the levels of the glucose-regulated proteins. Cancer Res. 52:3814–3817.
   PubMedGoogle Scholar
• Pulverer, B. J., J. M. Kyriakis, J. Avruch, E. Nikolakaki, and J. R. Woodgett. 1991. Phosphorylation of c-jun mediated by MAP kinases. Nature (London) 353:670–674.
   PubMed Web of Science ®Google Scholar
• Quantin, B., and R. Breathnach. 1988. Epidermal growth factor stimulates transcription of the c-jun proto-oncogene in rat fibroblasts. Nature (London) 334:538–539.
   PubMed Web of Science ®Google Scholar
• Rice, G. C., C. Hoy, and R. T. Schimke. 1986. Transient hypoxia enhances the frequency of dihydrofolate reductase gene amplification in Chinese hamster ovary cells. Proc. Natl. Acad. Sci. USA 83:5978–5982.
   PubMed Web of Science ®Google Scholar
• Rice, G. C., V. Ling, and R. T. Schimke. 1987. Frequencies of independent and simultaneous selection of Chinese hamster cells for methotrexate and doxorubicin (adriamycin) resistance. Proc. Natl. Acad. Sci. USA 84:9261–9264.
   PubMedGoogle Scholar
• Roll, D. E., B. J. Murphy, K. R. Laderoute, R. M. Sutherland, and H. C. Smith. 1991. Oxygen regulated 80 kDa protein and glucose regulated 78 kDa protein are identical. Mol. Cell. Biochem. 103:141–148.
   PubMedGoogle Scholar
• Sakata, K., T. T. Kwok, B. J. Murphy, K. R. Laderoute, G. R. Gordon, and R. M. Sutherland. 1991. Hypoxia-induced drug resistance: comparison to P-glycoprotein-associated drug resistance. Br. J. Cancer 64:809–814.
   PubMed Web of Science ®Google Scholar
• Schönthal, A., S. Srinivas, and W. Eckhart. 1992. Induction of c-jun protooncogene expression and transcription factor AP-1 activity by the polyoma virus middle-sized tumor antigen. Proc. Natl. Acad. Sci. USA 89:4972–4976.
   PubMedGoogle Scholar
• Schütte, J., J. D. Minna, and M. J. Birrer. 1989. Deregulated expression of human c-jun transforms primary rat embryo cells in cooperation with an activated c-Ha-ras gene and transforms Rat-la cells as a single gene. Proc. Natl. Acad. Sci. USA 86:2257–2261.
   PubMed Web of Science ®Google Scholar
• Sciandra, J. J., J. R. Subjeck, and C. S. Hughes. 1984. Induction of glucose-regulated proteins during anaerobic exposure and of heat-shock proteins after reoxygenation. Proc. Natl. Acad. Sci. USA 81:4843–4847.
   PubMed Web of Science ®Google Scholar
• Seto, E., P. J. Mitchell, and T. S. B. Yen. 1990. Transactivation by the hepatitis Β virus X protein depends on AP-2 and other transcription factors. Nature (London) 344:72–74.
   PubMed Web of Science ®Google Scholar
• Shweiki, D., A. Itin, D. Soffer, and E. Keshet. 1992. Vascular endothelial growth factor induced by hypoxia may mediate hy-poxia-initiated angiogenesis. Nature (London) 359:843–845.
   PubMed Web of Science ®Google Scholar
• Smeal, Τ., Β. Binétruy, D. Mercola, A. Grover-Bardwick, G. Heidecker, U. R. Rapp, and M. Karin. 1992. Oncoprotein-mediated signalling cascade stimulates c-Jun activity by phosphorylation of serines 63 and 73. Mol. Cell. Biol. 12:3507–3513.
   PubMed Web of Science ®Google Scholar
• Stein, B., P. Angel, H. van Dam, H. Ponta, P. Herrlich, A. van der Eb, and H. J. Rahmsdorf. 1992. Ultraviolet-radiation induced c-jun gene transcription: two AP-1 like binding sites mediate the response. Photochem. Photobiol. 55:409–415.
   PubMedGoogle Scholar
• Stoler, D. L., G. R. Anderson, C. A. Russo, A. M. Spina, and T. A. Beerman. 1992. Anoxia-inducible endonuclease activity as a potential basis of the genomic instability of cancer cells. Cancer Res. 52:4372–4378.
   PubMed Web of Science ®Google Scholar
• Turner, R., and R. Tjian. 1989. Leucine repeats and an adjacent DNA binding domain mediate the formation of functional cFos-cJun heterodimers. Science 243:1689–1694.
   PubMed Web of Science ®Google Scholar
• van Dam, H., M. Duyndam, R. Rottier, A. Bosch, L. de Vries-Smits, P. Herrlich, A. Zantema, P. Angel, and A. J. van der Eb. 1993. Heterodimer formation of cJun and ATF-2 is responsible for induction of c-jun by the 243 amino acid adenovirus E1A protein. EMBO J. 12:479–487.
   PubMed Web of Science ®Google Scholar
• Vogt, P. K., and T. J. Bos. 1990. jun: oncogene and transcription factor. Adv. Cancer Res. 55:1–35.
   PubMedGoogle Scholar
• Xanthoudakis, S., and T. Curran. 1992. Identification and characterization of Ref-1, a nuclear protein that facilitates AP-1 DNA-binding activity. EMBO J. 11:653–665.
   PubMed Web of Science ®Google Scholar
• Xanthoudakis, S., G. Miao, F. Wang, Y.-C. E. Pan, and T. Curran. 1992. Redox activation of Fos-Jun DNA binding activity is mediated by a DNA repair enzyme. EMBO J. 11:3323–3335.
   PubMed Web of Science ®Google Scholar
• Yoshida, T., P. Biro, T. Cohen, R. M. Müller, and S. Shibahara. 1988. Human heme oxygenase cDNA and induction of its mRNA by hemin. Eur. J. Biochem. 171:457–461.
   PubMedGoogle Scholar
• Young, S. D., R. S. Marshall, and R. P. Hill. 1988. Hypoxia induces DNA overreplication and enhances metastatic potential of murine tumor cells. Proc. Natl. Acad. Sci. USA 85:9533–9537.
   PubMed Web of Science ®Google Scholar