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Research Article

Gene Induction by Interferons and Double-Stranded RNA: Selective Inhibition by 2-Aminopurine

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Pages 4289-4294 | Received 26 May 1988, Accepted 27 Jul 1988, Published online: 31 Mar 2023

Literature Cited

  • Baglioni, C., and T. W. Nilsen. 1983. Mechanisms of antiviral action of interferon. Interferon 5:23-42.
  • Benech, P., M. Vigneron, D. Peretz, M. Revel, and J. Chebath. 1987. Interferon-responsive regulatory elements in the promoter of the human 2′,5′-oligo(A) synthetase gene. Mol. Cell. Biol. 7:4498-4504.
  • Caplen, H. C., and S. L. Gupta. 1988. Differential regulation of a cellular gene by human interferon-y and interferon-a. J. Biol. Chem. 263:332-339.
  • Cohen, B., D. Peretz, D. Vaiman, P. Benech, and J. Chebath. 1988. Enhancer-like interferon responsive sequences of the human and murine (2′-5′) oligoadenylate synthetase gene promoters. EMBO J. 7:1411-1419.
  • De Benedetti, A., and C. Baglioni. 1983. Phosphorylation of initiation factor eIF-2a, binding of mRNA to 48S complexes, and its reutilization in initiation of protein synthesis. J. Biol. Chem. 258:14556-14562.
  • Enoch, T., K. Zinn, and T. Maniatis. 1986. Activation of the human p-interferon gene requires an interferon-inducible factor. Mol. Cell. Biol. 6:801-810.
  • Farrell, P. J., K. Balkow, T. Hunt, R. J. Jackson, and H. Trachsel. 1977. Phosphorylation of initiation factor eIF-2 and the control of reticulocyte protein synthesis. Cell 11:187-200.
  • Friedman, R. L., S. P. Manly, M. McMahon, I. M. Kerr, and G. R. Stark. 1984. Transcriptional and post-transcriptional regulation of interferon-induced gene expression in human cells. Cell 38:745-755.
  • Fujita, T., H. Shibuya, H. Hotta, K. Yamanishi, and T. Taniguchi. 1987. Interferon-p gene regulation: tandemly repeated sequences of a synthetic 6 bp oligomer function as a virusinducible enhancer. Cell 49:357-367.
  • Goodbourn, S., and T. Maniatis. 1988. Overlapping positive and negative regulatory domains of the human β-interferon gene. Proc. Natl. Acad. Sci. USA 85:1447-1451.
  • Holmes, S. L., and S. L. Gupta. 1982. Interferon action in human fibroblasts: induction of 2′,5′-oligoadenylate synthetase in the absence of detectable protein kinase activity. Arch. Virol. 72:137-142.
  • Kaufman, R. J., and P. Murtha. 1987. Translational control mediated by eucaryotic initiation factor-2 is restricted to specific mRNAs in transfected cells. Mol. Cell. Biol. 7:1568-1571.
  • Keller, A. D., and T. Maniatis. 1988. Identification of an inducible factor that binds to a positive regulatory element of the human p-interferon gene. Proc. Natl. Acad. Sci. USA 85:3309-3313.
  • Kusari, J., and G. C. Sen. 1986. Regulation of synthesis and turnover of an interferon-inducible mRNA. Mol. Cell. Biol. 6:2062-2067.
  • Kusari, J., and G. C. Sen. 1987. Transcriptional analyses of interferon-inducible mRNAs. Mol. Cell. Biol. 7:528-531.
  • Kusari, J., R. K. Tiwari, R. Kumar, and G. C. Sen. 1987. Expression of interferon-inducible genes in RD-114 cells. J. Virol. 61:1524-1531.
  • Larner, A. C., G. Jonak, Y.S.-E. Cheng, B. Korant, E. Knight, and J. E. Darnell. 1984. Transcriptional induction of two genes in human cells by β-interferon. Proc. Natl. Acad. Sci. USA 81:6733-6737.
  • Legon, S., A. Brayley, T. Hunt, and R. J. Jackson. 1974. The effect of cyclic AMP and related compounds on the control of protein synthesis in reticulocyte lysates. Biochem. Biophys. Res. Commun. 56:745-752.
  • Lengyel, P. 1982. Biochemistry of interferons and their actions. Annu. Rev. Biochem. 51:251-282.
  • Levy, D. E., D. S. Kessler, R. Pine, N. Reich, and J. E. Darnell, Jr. 1988. Interferon-induced nuclear factors that bind a shared promoter element correlate with positive and negative transcriptional control. Genes Dev. 2:383-393.
  • Luster, A. D., J. C. Unkeless, and J. V. Ravetch. 1985. γ- interferon transcriptionally regulates an early response gene containing homology to platelet proteins. Nature (London) 315:672-676.
  • Marcus, P. I. 1984. Interferon induction by viruses: doublestranded RNA as the common proximal inducer molecule, p. 113-175. In R. M. Friedman (ed.), Interferon: mechanisms of production and action, vol. 3. Elsevier Biomedical Press, Amsterdam.
  • Marcus, P., and M. J. Sekellick. 1977. Defective interfering particles with covalently linked [+/-]RNA induce interferon. Nature (London) 266:815-819.
  • Marcus, P. L., and M. J. Sekellick. 1988. Interferon induction by viruses. XVI. 2-Aminopurine blocks selectively and reversibly an early stage in interferon induction. J. Gen. Virol. 69:1637-1645.
  • Merlin, G., J. Chebath, P. Benech, R. Metz, and M. Revel. 1983. Molecular cloning and sequence of partial cDNA for interferon induced (2′-5′) oligo(A)synthetase mRNA from human cells. Proc. Natl. Acad. Sci. USA 80:4904-4908.
  • Pestka, S., J. A. Langer, K. C. Zoon, and C. E. Samuel. 1987. Interferons and their actions. Annu. Rev. Biochem. 56:727-767.
  • Porter, A. C. G., Y. Chernajovsky, T. C. Dale, C. S. Gilbert, G. R. Stark, and I. M. Kerr. 1988. Interferon response element of the human gene 6-16. EMBO J. 7:85-92.
  • Ragg, H., and C. Weissmann. 1983. Not more than 117 base pairs of 5′-flanking sequence are required for inducible expression of a human IFN-a gene. Nature (London) 303:439-442.
  • Reich, N., B. Evans, D. Levy, D. Fahey, E. Knight, Jr., and D. E. Darnell, Jr. 1987. Interferon-induced transcription of a gene encoding a 15-kDa protein depends on an upstream enhancer element. Proc. Natl. Acad. Sci. USA 84:6394-6398.
  • Revel, M., and J. Chebath. 1986. Interferon-activated genes. Trends Biochem Sci. 11:166-170.
  • Rubin, B. Y., S. L. Anderson, R. M. Lunn, G. R. Hellerman, N. K. Richardson, and L. J. Smith. 1988. Production of a monoclonal antibody directed against an interferon-induced 56,000-dalton protein and its use in the study of this protein. J. Virol. 62:1875-1880.
  • Rutherford, M. N., G. E. Hannigan, and B. R. G. Williams. 1988. Interferon-induced binding of nuclear factors to promoter elements of the 2-5A synthetase gene. EMBO J. 7:751-759.
  • Samanta, H., J. P. Dougherty, M. E. Brawner, H. Schmidt, and P. Lengyel. 1982. Interferon action: cloning of cDNA segments complementary to messenger RNAs induced by interferons. UCLA Symp. Mol. Cell. Biol. 25:59-72.
  • Samanta, H., D. A. Engel, H. M. Chao, A. Thakur, M. A. Garcia-Blanco, and P. Lengyel. 1986. Interferons as gene activators: cloning of the 5′ terminus and the control segment of an interferon activated gene. J. Biol. Chem. 261:11849-11858.
  • Saunders, M. E., D. R. Gewert, M. E. Tugwell, M. McMahon, and B. R. G. Williams. 1985. Human 2-5A synthetase: characterization of a novel cDNA and corresponding gene structure. EMBO J. 4:1761-1768.
  • Sen, G. C. 1984. Biochemical pathways in interferon action. Pharmacol. Ther. 24:235-257.
  • Staeheli, P., P. Danielson, O. Haller, and J. G. Sutcliffe. 1986. Transcriptional activation of the mouse Mx gene by type I interferon. Mol. Cell. Biol. 6:4770-4774.
  • Stewart, W. E., II. 1981. The interferon system, 2nd ed., Springer-Verlag, Vienna.
  • Tiwari, R. K., J. Kusari, and G. C. Sen. 1987. Functional equivalents of interferon-mediated signals needed for induction of an mRNA can also be generated by double-stranded RNA and growth factors. EMBO J. 6:3373-3378.
  • Wathelet, M. G., I. M. Clauss, C. B. Nols, J. Content, and G. A. Huez. 1987. New inducers revealed by the promoter sequence analysis of two interferon-activated human genes. Eur. J. Biochem. 169:313-321.
  • Wathelet, M. G., S. Moutschen, P. Defilippi, A. Cravador, M. Collet, G. Huez, and J. Content. 1986. Molecular cloning: full-length sequence and preliminary characterization of a 56kDa protein induced by human interferons. Eur. J. Biochem. 155:1-7.
  • Weissmann, C., and H. Weber. 1986. The interferon genes. Prog. Nucleic Acid Res. 33:251-300.
  • Zinn, K., A. Keller, L.-A. Whittemore, and T. Maniatis. 1988. 2-Aminopurine selectively inhibits the induction of p-interferon, c-fos, and c-myc gene expression. Science 240:210-213.
  • Zullo, J. N., B. H. Cochran, A. S. Huang, and C. D. Stiles. 1985. Platelet-derived growth factor and double-stranded ribonucleic acids stimulate expression of the same genes in 3T3 cells. Cell 43:793-800.

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