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Research Article

Recessive Genetic Deregulation Abrogates c-myc Suppression by Interferon and Is Implicated in Oncogenesis

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Pages 2828-2836 | Received 12 Feb 1988, Accepted 22 Mar 1988, Published online: 31 Mar 2023

LITERATURE CITED

  • Adams, J. M., A. W. Harris, C. A. Pinkert, L. M. Corcoran, W. S. Alexander, S. Cory, R. D. Palmiter, and R. L. Brinster. 1985. The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice. Nature (London) 318:533–538.
  • Bentley, D. L., and M. Groudine. 1986. A block to elongation is largely responsible for decreased transcription of c-myc in differentiated HL60 cells. Nature (London) 321:702–706.
  • Bishop, J. M. 1985. Viral oncogenes. Cell 42:23–38.
  • Cheley, S., and R. Anderson. 1984. A reproducible microanalytical method for the detection of specific RNA sequences by dot-blot hybridization. Anal. Biochem. 137:15–19.
  • Dalla-Favera, R., S. Martinotti, R. C. Gallo, J. Erikson, and C. M. Croce. 1983. Translocation and rearrangements of the c-myc oncogene locus in human undifferentiated B-cell lymphomas. Science 219:963–967.
  • Dani, C. H., N. Mechti, M. Piechaczyk, B. Lebleu, P. H. Jeenteur, and J. M. Blanchard. 1985. Increased rate of degradation of c-myc mRNA in interferon-treated Daudi cells. Proc. Natl. Acad. Sci. USA 82:4896–4899.
  • Dony, C., M. Kessel, and P. Gruss. 1985. Post-transcriptionalcontrol of myc and p53 expression during differentiation of the embryonal carcinoma cell line F9. Nature (London) 317:636–639.
  • Dron, M., N. Modjtahedi, O. Brison, and M. G. Tovey. 1986. Interferon modulation of c-myc expression in cloned Daudi cells: relationship to the phenotype of interferon resistance. Mol. Cell. Biol. 6:1374–1378.
  • Dyson, P. J., and T. H. Rabitts. 1985. Chromatin structure around the c-myc gene in Burkitt lymphomas with upstream and downstream translocation points. Proc. Natl. Acad. Sci. USA 82:1984–1988.
  • Einat, M., D. Resnitzky, and A. Kimchi. 1985. Close links between reduction of c-myc expression by interferon and G0/G1 arrest. Nature (London) 313:597–600.
  • Einat, M., D. Resnitzky, and A. Kimchi. 1985. Inhibitory effects of interferon on the expression of genes regulated by platelet-derived growth factor. Proc. Natl. Acad. Sci. USA 82:7608–7612.
  • Ernberg, J., S. Einhorn, H. Strander, and G. Klein. 1981. Proliferation inhibitory effect of human α interferon on primary explants of Burkitt lymphoma: inverse relationship to patient survival. Biomedicine (Paris) 35:190–193.
  • Friedman-Einat, M., M. Revel, and A. Kimchi. 1982. Initial characterization of a spontaneous interferon secreted during growth and differentiation of Friend erythroleukemia cells. Mol. Cell. Biol. 2:1472–1480.
  • Friend, S. H., R. Bernards, S. Rogelj, R. A. Weinberg, J. M. Rapaport, D. M. Albert, and T. P. Dryja. 1986. A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma. Nature (London) 323:643–646.
  • Gonda, T. J., and D. Metcalf. 1984. Expression of myb, myc and fos proto-oncogenes during the differentiation of a murine myeloid leukemia. Nature (London) 310:249–251.
  • Heldin, C. H., and B. Westermark. 1984. Growth factors: mechanism of action and relation to oncogenes. Cell 37:9–20.
  • Jonak, G. J., and E. Knight, Jr. 1984. Selective reduction of c-myc mRNA in Daudi cells by human β-interferon. Proc. Natl. Acad. Sci. USA 81:1747–1750.
  • Kelly, K., B. H. Cochran, C. D. Stiles, and P. Leder. 1983. Cell-specific regulation of the c-myc gene by lymphocyte mitogens and platelet-derived growth factor. Cell 35:603–610.
  • Kimchi, A., D. Resnitzky, R. Bendori, and M. Einat. 1985. Down regulation of the c-myc and the p53 genes by interferon is tightly associated with IFN mediated G0/G1 arrest. p. 205–212. In H. Kirchner and H. Schellenkens (ed.), The biology of the interferon system. Elsevier Science Publishers B.V., Amsterdam.
  • Klein, G., and E. Klein. 1985. Evolution of tumours and the impact of molecular oncology. Nature (London) 315:190–195.
  • Klein, G., J. Zeuthen, R. Ber, and I. Ernbserg. 1982. Human lymphoma-lymphoma hybrids and lymphoma-leukemia hybrids. II. Epstein-Barr virus induction patterns. JNCI 68:197–202.
  • Knight, E., Jr., E. D. Anton, D. Fahey, B. K. Friedland, and G. J. Jonak. 1985. Interferon regulates c-myc gene expression in Daudi cells at the post-transcriptional level. Proc. Natl. Acad. Sci. USA 82:1151–1154.
  • Knudson, A. G., Jr. 1985. Hereditary cancer, oncogenes, and antioncogenes. Cancer Res. 45:1437–1443.
  • Krishnan, L., and C. Baglioni. 1980. Increased levels of (2′-5′) oligo(A) polymerase activity in human lymphoblastoid cells treated with glucocorticoids. Proc. Natl. Acad. Sci. USA 77:6506–6510.
  • Lachman, H. M., and A. I. Skoultchi. 1984. Expression of c-myc changes during differentiation of mouse erythroleukaemia cells. Nature (London) 310:592–594.
  • Land, H., L. F. Parada, and R. A. Weinberg. 1983. Cellular oncogenes and multistep carcinogenesis. Science 222:771–778.
  • Leder, P., J. Battey, G. Lenoir, C. Modulding, W. Murphy, H. Potter, T. Stewart, and R. Taub. 1983. Translocations among antibody genes in human cancer. Science 222:765–771.
  • Lee, W. H., P. Bookstein, F. Hong, L. J. Young, J. Y. Shew, and E. Y.-H. P. Lee. 1987. Human retinoblastoma susceptibility gene: cloning and sequence. Science 235:1394–1395.
  • Merlin, G., J. Chebath, P. Benech, R. Metz, and M. Revel. 1983. Molecular cloning and sequence of partial cDNA for (2′-5′) oligo(A) synthetase mRNA from human cells. Proc. Natl. Acad. Sci. USA 80:4904–4908.
  • Nicola, N. A., D. Metcalf, M. Matsumoto, and G. R. Johnson. 1983. Purification of a factor inducing differentiation in murine myelomonocytic leukemia cells: identification as granulocyte colony stimulating factor. J. Biol. Chem. 258:9017–9023.
  • Novick, D., Z. Eshhar, and M. Rubinstein. 1982. Monoclonal antibodies to human α-interferon and their use for affinity chromatography. J. Immunol. 129:2244–2247.
  • Rabitts, T. H., A. Forster, P. Hamlyn, and R. Baer. 1984. Effect of somatic mutation within translocated c-myc genes in Burkitt's lymphoma. Nature (London) 309:592–597.
  • Resnitzky, D., A. Yarden, D. Zipori, and A. Kimchi. 1986. Autocrine β-related interferon controls c-myc suppression and growth arrest during hematopoietic cell differentiation. Cell 46:31–40.
  • Rushdi, A., K. Nishikura, J. Erikson, R. Watt, G. Rovera, and C. M. Croce. 1983. Differential expression of the translocated and the untranslocated c-myc oncogene in Burkitt lymphoma. Science 222:390–393.
  • Sager, R. 1986. Genetic suppression of tumor formation: a new frontier in cancer research. Cancer Res. 46:1573–1580.
  • Siebenlist, V., L. Hennighausen, J. Battey, and P. Leder. 1984. Chromatin structure and protein binding in the putative regulatory region of the c-myc gene in Burkitt lymphoma. Cell 37:381–391.
  • Stewart, T. A., P. K. Pattengale, and P. Leder. 1984. Spontaneous mammary adenocarcinomas in transgenic mice that carry and express MTV/myc fusion genes. Cell 38:627–637.
  • Takeda, K., S. Iwamoto, H. Sugimoto, T. Takuma, N. Kawatani, M. Noda, A. Masaki, H. Morise, H. Arimura, and K. Konno. 1986. Identity of differentiation inducing factor and tumour necrosis factor. Nature (London) 323:338–340.
  • Taub, R., C. Moulding, J. Battey, W. Murphy, T. Vasicek, G. M. Lenoir, and P. Leder. 1984. Activation and somatic mutation of the translocated c-myc gene in Burkitt lymphoma cells. Cell 36:339–348.
  • Westin, E. H., F. Wong-Staal, E. P. Gelmann, R. Dalla Favera, T. S. Papas, J. A. Lautenberger, A. Eva, E. P. Reddy, S. R. Tronick, S. A. Aaronson, and R. C. Gallo. 1982. Expression of cellular homologues of retroviral onc genes in human hematopoietic cells. Proc. Natl. Acad. Sci. USA 79:2490–2494.
  • Yarden, A., and A. Kimchi. 1986. Tumor necrosis factor reduces c-myc expression and cooperates with interferon-γ in HeLa cells. Science 234:1419–1421.
  • Yarden, A., H. Shure-Gottlieb, J. Chebath, M. Revel, and A. Kimchi. 1984. Autogenous production of interferon-β switches on HLA genes during differentiation of histiocytic lymphoma U937 cells. EMBO J. 3:969–973.
  • Zeuthen, J., G. Klein, R. Ber, G. Masucci, S. Bisballe, S. Povey, P. Terasaki, and P. Ralph. 1982. Human lymphoma-lymphoma hybrids and lymphoma-leukemia hybrids. I. Isolation, characterization, cell surface markers, and B-cell markers. JNCI 68:179–195.

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