19
Views
22
CrossRef citations to date
0
Altmetric
Research Article

Organization of the Murine Mx Gene and Characterization of Its Interferon- and Virus-Inducible Promoter

, , , &
Pages 3065-3079 | Received 08 Feb 1988, Accepted 18 Apr 1988, Published online: 31 Mar 2023

Literature Cited

  • Anderson, S. 1981. Shotgun DNA sequencing using cloned DNasel-generated fragments. Nucleic Acids Res. 9:3015-3027.
  • Arnheiter, H., O. Haller, and J. Lindenmann. 1980. Host gene influence on interferon action in adult mouse hepatocytes: specificity for influenza virus. Virology 103:11-20.
  • Arnheiter, H., and P. Staeheli. 1983. Expression of IFN-depen-dent resistance to influenza virus in mouse embryo cells. Arch. Virol. 76:127-137.
  • Auffray, C., and F. Rougeon. 1980. Purification of mouse immunoglobulin heavy-chain messenger RNAs from total myeloma tumor RNA. Eur. J. Biochem. 107:303-314.
  • Benech, P., Μ. Vigneron, D. Peretz, Μ. Revel, and J. Chebath. 1987. Interferon-responsive elements in the promoter of the human 2′,5′-oligo(A) synthetase gene. Mol. Cell. Biol. 7:4498-4504.
  • Breathnach, R., and P. Chambon. 1981. Organization and expression of eukaryotic split genes coding for proteins. Annu. Rev. Biochem. 50:349-383.
  • Bucher, P., and E. N. Trifonov. 1986. Compilation and analysis of eukaryotic POL II promoter sequences. Nucleic Acids Res. 14:10009-10026.
  • Das, H. K., S. K. Lawrance, and S. Μ. Weissman. 1983. Structure and nucleotide sequence of the heavy chain gene of HLA-DR. Proc. Natl. Acad. Sci. USA 80:3543-3547.
  • Dierks, P., A. van Ooyen, Μ. D. Cochran, C. Dobkin, J. Reiser, and C. Weissmann. 1983. Three regions upstream from the cap site are required for efficient and accurate transcription of the rabbit β-globin gene in mouse 3T6 cells. Cell 32:695-706.
  • Dreiding, P., P. Staeheli, and O. Haller. 1985. Interferon-induced protein Mx accumulates in nuclei of mouse cells expressing resistance to influenza viruses. Virology 140:192-196.
  • Efstratiadis, A., F. C. Kafatos, and T. Maniatis. 1977. The primary structure of rabbit β-globin mRNA as determined from cloned DNA. Cell 10:571-585.
  • Enoch, T., K. Zinn, and T. Maniatis. 1986. Activation of the human β-interferon gene requires an interferon-inducible factor. Mol. Cell. Biol. 6:801-810.
  • Friedman, R. L., and G. R. Stark. 1985. α-Interferon-induced transcription of HLA and metallothionein genes containing homologous upstream sequences. Nature (London) 314:637-639.
  • Frischauf, A.-U., H. Lehrach, A. Poustka, and N. Murray. 1983. Lambda replacement vectors carrying polylinker sequences. J. Mol. Biol. 170:827-842.
  • Fujita, T., S. Ohno, H. Yasumitsu, and T. Taniguchi. 1985. Delimitation and properties of DNA sequences required for the regulated expression of human interferon-β gene. Cell 41:489-496.
  • Fujita, T., H. Shibuya, H. Hotta, K. Yamanishi, and T. Taniguchi. 1987. Interferon-β gene regulation: tandemly repeated sequences of a synthetic 6 bp oligomer function as a virusinducible enhancer. Cell 49:357-367.
  • Fujita, T., H. Shibuya, T. Ohashi, K. Yamanishi, and T. Taniguchi. 1986. Regulation of humam interleukin-2 gene: functional DNA sequences in the 5′ flanking region for the gene expression in activated T lymphocytes. Cell 46:401-407.
  • Georgi, C., B. Μ. Blumberg, and D. Kolakofsky. 1983. Sendai virus contains overlapping genes expressed from a single mRNA. Cell 35:829-836.
  • Grosveld, F. G., H.-H. Μ. Dahl, E. de Boer, and R. A. Flaveil. 1981. Isolation of β-globin-related genes from a human cosmid library. Gene 13:227-237.
  • Haller, O., H. Arnheiter, I. Gresser, and J. Lindenmann. 1979. Genetically determined, interferon-dependent resistance to influenza virus in mice. J. Exp. Med. 149:601-612.
  • Haller, O., H. Arnheiter, J. Lindenmann, and I. Gresser. 1980. Host gene influences sensitivity to interferon action selectively for influenza virus. Nature (London) 283:660-662.
  • Hayashi, S., and H. Kondoh. 1986. In vivo competition of δ-crystallin gene expression by DNA fragments containing a GC box. Mol. Cell. Biol. 6:4130-4132.
  • Horisberger, Μ. A., P. Staeheli, and O. Haller. 1983. Interferon induces a unique protein in mouse cells bearing a gene for resistance to influenza virus. Proc. Natl. Acad. Sci. USA 80:1910-1914.
  • Israel, A., A. Kimura, A. Fournier, Μ. Fellous, and P. Kourilsky. 1986. Interferon response sequence potentiates activity of an enhancer in the promoter region of a mouse H-2 gene. Nature (London) 322:743-746.
  • Jones, K. A., and R. Tjian. 1985. Spl binds to promoter sequences and activated herpes simplex virus “immediate-early” gene transcription in vitro. Nature (London) 317:179-182.
  • Kadonaga, J. T., K. A. Jones, and R. Tjian. 1986. Promoterspecific activation of RNA polymerase II transcription by Spl. Trends Biochem. Sci. 11:20-23.
  • Karin, Μ., and R. I. Richards. 1982. Human metallothionein genes—primary structure of the metallothionein-II gene and a related processed gene. Nature (London) 299:797-802.
  • Kimura, A., A. Israel, O. Le Bail, and P. Kourilsky. 1986. Detailed analysis of the mouse H-2Kb promoter: enhancer-like sequences and their role in the regulation of class I gene expression. Cell 44:261-272.
  • Korber, B., L. Hood, and I. Stroynowski. 1987. Regulation of murine class I genes by interferons is controlled by regions located both 5′ and 3′ to the transcription initiation site. Proc. Natl. Acad. Sci. USA 84:3380-3384.
  • Kuhl, D., J. de la Fuente, Μ. Chaturvedi, S. Parimoo, J. Ryals, F. Meyer, and C. Weissmann. 1987. Reversible silencing of enhancers by sequences derived from the human IFN-α promoter. Cell 50:1057-1069.
  • Levy, D., A. Larner, A. Chaudhuri, L. E. Babiss, and J. E. Darnell, Jr. 1986. Interferon-stimulated transcription: isolation of an inducible gene and identification of its regulatory region. Proc. Natl. Acad. Sci. USA 83:8929-8933.
  • Lindenmann, J. 1962. Resistance of mice to mouse adapted influenza A virus. Virology 16:203-204.
  • Luster, A. D., and J. V. Ravetch. 1987. Genomic characterization of a gamma-interferon-inducible gene (IP-10) and identification of an interferon-inducible hypersensitive site. Mol. Cell. Biol. 7:3723-3731.
  • Luster, A. D., J. C. Unkeless, and J. V. Ravetch. 1985. γ-Interferon transcriptionally regulates an early-response gene containing homology to platelet proteins. Nature (London) 315:672-676.
  • Malissen, Μ., B. Malissen, and B. R. Jordan. 1982. Exon/intron organization and complete nucleotide sequence of an HL A gene. Proc. Natl. Acad. Sci. USA 79:893-897.
  • Maniatis, T., E. Fritsch, and J. Sambrook. 1982. Molecular cloning: a laboratory manual. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
  • Mantei, N., and C. Weissmann. 1982. Controlled transcription of a human a-interferon gene introduced into mouse L cells. Nature (London) 297:128-132.
  • Maxam, A. Μ., and W. Gilbert. 1977. A new method for sequencing DNA. Proc. Natl. Acad. Sci. USA 74:560-564.
  • Melton, D. A., P. A. Krieg, Μ. R. Rebagliati, T. Maniatis, K. Zinn, and Μ. R. Green. 1984. Efficient in vitro synthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter. Nucleic Acids Res. 12:7035-7056.
  • Mount, S. Μ. 1982. A catalogue of splice junction sequences. Nucleic Acids Res. 10:459-472.
  • Noteborn, Μ., H. Arnheiter, L. Richter-Mann, H. Browning, and C. Weissmann. 1987. Transport of the murine Mx protein into the nucleus is dependent on a basic carboxy-terminal sequence. J. Interferon Res. 7:657-669.
  • Porter, A. C. G., Y. Chernajovsky, C. S. Gilbert, G. R. Stark, and I. Μ. Kerr. 1987. Interferon response element of the human gene 6-16. EMBO J. 7:85-92.
  • Reich, N., B. Evans, D. Levy, D. Fahey, E. Knight, Jr., and J. Darnell, Jr. 1987. Interferon-induced transcription of a gene encoding a 15-kDa protein depends on an upstream enhancer element. Proc. Natl. Acad. Sci. USA 84:6394-6398.
  • Revel, Μ., and J. Chebath. 1986. Interferon-activated genes. Trends Biochem. Sci. 11:166-170.
  • Ryals, J., P. Dierks, H. Ragg, and C. Weissmann. 1985. A 46-nucleotide promoter segment from an IFN-α gene renders an unrelated promoter inducible by virus. Cell 41:497-507.
  • Samanta, H., D. A. Engel, H. Μ. Chao, A. Thakur, Μ. A. Garcia-Blanco, and P. Lengyel. 1986. Interferons as gene activators. J. Biol. Chem. 261:11849-11858.
  • Shapiro, Μ. B., and P. Senapathy. 1987. RNA splice junctions of different classes of eukaryotes: sequence statistics and functional implications in gene expression. Nucleic Acids Res. 15:7155-7174.
  • Shaw, G. D., W. Boll, H. Taira, N. Mantei, P. Lengyel, and C. Weissmann. 1983. Structure and expression of cloned murine IFN-α genes. Nucleic Acids Res. 11:555-573.
  • Smith, H. O., and Μ. L. Birnstiel. 1976. A simple method for DNA restriction site mapping. Nucleic Acids Res. 3:2387-2398.
  • Southern, E. Μ. 1975. Detection of specific sequences among DNA fragments separated by gel electrophoresis. J. Mol. Biol. 98:503-517.
  • Staeheli, P., P. Danielson, O. Haller, and J. G. Sutcliffe. 1986. Transcriptional activation of the mouse Mx gene by type I interferon. Mol. Cell. Biol. 6:4770-4774.
  • Staeheli, P., P. Dreiding, О. Haller, and J. Lindenmann. 1985. Polyclonal and monoclonal antibodies to the interferon-inducible protein Mx of influenza virus-resistant mice. J. Biol. Chem. 260:1821-1825.
  • Staeheli, P., O. Haller, W. Boll, J. Lindenmann, and C. Weissmann. 1986. Mx protein: constitutive expression in 3T3 cells transformed with cloned Mx cDNA confers selective resistance to influenza virus. Cell 44:147-158.
  • Staeheli, P., Μ. A. Horisberger, and O. Haller. 1984. Mx-dependent resistance to influenza virus induced by mouse interferons alpha and beta but not gamma. Virology 132:456-461.
  • Strachan, T., R. Sodoyer, Μ. Damotte, and B. R. Jordan. 1984. Complete nucleotide sequence of a functional class I HLA gene, HLA-A3: implications for the evolution of HLA genes. EMBO J. 3:887-894.
  • Sugita, K., J.-I. Miyazaki, E. Appella, and K. Ozato. 1987. Interferons increase transcription of a major histocompatibility class I gene via a 5′ interferon consensus sequence. Mol. Cell. Biol. 7:2625-2630.
  • Tiwari, R. K., J. Kusari, and G. C. Sen. 1987. Functional equivalents of interferon-mediated signals needed for induction of an mRNA can be generated by double-stranded RNA and growth factors. EMBO J. 6:3373-3378.
  • Wathelet, Μ. G., I. Μ. Clauss, С. B. Nols, J. Content, and G. A. Huez. 1987. New inducers revealed by the promoter sequence analysis of two interferon-activated human genes. Eur. J. Biochem. 109:313-321.
  • Weidle, U., and C. Weissmann. 1983. The 5′-flanking region of a human IFN-a gene mediates viral induction of transcription. Nature (London) 303:442-446.
  • Weil, H., C. J. Epstein, L. B. Epstein, J. J. Sedmak, J. L. Sabran, and S. E. Grossberg. 1983. A unique set of polypeptides is induced by gamma interferon in addition to those induced in common with alpha and beta interferons. Nature (London) 301:437-439.
  • Weissmann, C., and H. Weber. 1986. The interferon genes. Prog. Nucleic Acid Res. Mol. Biol. 33:251-300.
  • Wood, W. L., J. Gitschier, L. A. Lasky, and R. Μ. Lawn. 1985. Base composition-independent hybridization in tetramethylammonium chloride: a method for oligonucleotide screening of highly complex gene libraries. Proc. Natl. Acad. Sci. USA 82:1585-1588.
  • Wu, L.-С., B. J. Morley, and R. D. Campbell. 1987. Cell-specific expression of the human complement protein factor B gene: evidence for the role of two distinct 5′-flanking elements. Cell 48:331-342.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.