0
Views
6
CrossRef citations to date
0
Altmetric
Research Article

Evolution, Expression, and Chromosomal Location of a Novel Receptor Tyrosine Kinase Gene, eph

, , &
Pages 3770-3776 | Received 08 Feb 1988, Accepted 06 Jun 1988, Published online: 31 Mar 2023

LITERATURE CITED

  • Anderson, S. K., C. P. Gibbs, A. Tanaka, H. Kung, and D. J. Fujita. 1985. Human cellular src gene: nucleotide sequence and derived amino acid sequence of the region coding for the carboxy-terminal two-thirds of pp60c-src. Mol. Cell. Biol. 5:1122–1129.
  • Bargmann, C. I., M. Hung, and R. A. Weinberg. 1986. Multiple independent activations of the neu oncogene by a point mutation altering the transmembrane domain of pl85. Cell 45:649–657.
  • Signer, D. D., S. H. Signer, J. Ponten, B. Westermark, M. S. Mahaley, Jr., E. Ruoslahti, H. Herschman, L. F. Eng, and C. J. Wikstrand. 1981. Heterogeneity of genotypic and phenotypic characteristics of fifteen permanent cell lines derived from human gliomas. J. Neuropathol. Exp. Neurol. 40:201–229.
  • Birchmeier, C., D. Birnbaum, G. Waitches, O. Fasano, and M. Wigler. 1986. Characterization of an activated human ros gene. Mol. Cell. Biol. 6:3109–3116.
  • Bishop, J. M. 1987. The molecular genetics of cancer. Science 235:305–311.
  • Browning, P. J., H. F. Bunn, A. Cline, M. Shuman, and A. W. Nienhuis. 1986. "Replacement" of COOH-terminal truncation of v-fms with c-fms sequences markedly reduces transformation potential. Proc. Natl. Acad. Sci. USA 83:7800–7804.
  • Bubenik, J., M. Baresova, V. Viklicky, J. Jakoubkova, H. Sainerova, and J. Donner. 1973. Established cell line of urinary bladder carcinoma (T24) containing tumor-specific antigen. Int. J. Cancer 11:765–773.
  • Carpenter, G. 1987. Receptors for epidermal growth factor and other polypeptide mitogens. Annu. Rev. Biochem. 56:881–914.
  • Chirgwin, J. M., A. E. Przybyla, R. J. McDonald, and W. J. Rutter. 1979. Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry 18:5294–5299.
  • Collins, S. J., R. C. Gallo, and R. E. Gallagher. 1977. Continuous growth and differentiation of human myeloid leukemic cells in suspension culture. Nature (London) 270:347–349.
  • Coussens, L., T. L. Yang-Feng, Y. Liao, E. Chen, A. Gray, J. McGrath, P. H. Seeburg, T. A. Libermann, J. Schlessinger, U. Francke, A. Levinson, and A. Ullrich. 1985. Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogene. Science 230:1132–1139.
  • Coussens, L., C. V. Beveren, D. Smith, E. Chen, R. L. Mitchell, C. M. Isacke, I. M. Verma, and A. Ullrich. 1986. Structural alteration of viral homologue of receptor proto-oncogene fms at carboxy terminus. Nature (London) 320:277–280.
  • Dean, M., M. Park, M. M. Le Beau, T. S. Robins, M. O. Diaz, J. D. Rowley, D. G. Blair, and G. F. Vande Woude. 1985. The human met oncogene is related to the tyrosine kinase oncogenes. Nature (London) 318:385–388.
  • Di Fiore, P. P., J. H. Pierce, M. H. Kraus, O. Segatto, C. R. King, and S. A. Aaronson. 1987. erbB-2 is a potent oncogene when overexpressed in NIH/3T3 cells. Science 237:178–182.
  • Duesberg, P. H. 1985. Activated proto-oncogenes: sufficient or necessary for cancer? Science 228:669–677.
  • Ebina, Y., L. Ellis, K. Jarnagin, M. Edery, L. Graf, E. Clauser, J. Ou, F. Masiarz, Y. W. Kan, I. D. Goldfine, R. A. Roth, and W. J. Rutter. 1985. The human insulin receptor cDNA: the structural basis for hormone-activated transmembrane signalling. Cell 40:747–758.
  • Efstratiadis, A., J. W. Posakony, T. Maniatis, R. M. Lawn, C. O’Connell, R. A. Sprite, J. K. DeRiel, B. G. Forget, S. M. Weissman, J. L. Slightom, A. E. Blechl, O. Smithies, F. E. Baralle, C. C. Shoulders, and N. J. Proudfoot. 1980. The structure and evolution of the human beta-globin gene family. Cell 21:653–668.
  • Feinberg, A. P., and B. Vogelstein. 1983. A technique for radiolabelling DNA restriction endonuclease fragments to high specific activity. Anal. Biochem. 132:6–13.
  • Fernandez-Almonacid, R., and O. M. Rosen. 1987. Structure and ligand specificity of the Drosophila melanogaster insulin receptor. Mol. Cell. Biol. 7:2718–2727.
  • Fogh, J., J. M. Fogh, and T. Orfeo. 1977. One hundred and twenty-seven cultured human tumor cell lines producing tumors in nude mice. J. Natl. Cancer Inst. 59:221–225.
  • Foster, D. A., J. B. Levy, G. Q. Daley, M. C. Simon, and H. Hanafusa. 1986. Isolation of chicken cellular DNA sequences with homology to the region of viral oncogenes that encodes the tyrosine kinase domain. Mol. Cell. Biol. 6:325–331.
  • Fukushige, S., K. Matsubara, M. Yoshida, M. Sasaki, T. Suzuki, K. Semba, K. Toyoshima, and T. Yamamoto. 1986. Localization of a novel v-erbB-related gene, c-erbB-2, on human chromosome 17 and its amplification in a gastric cancer cell line. Mol. Cell. Biol. 6:955–958.
  • Gregory, R. J., K. L. Kammermeyer, W. S. Vincent III, and S. G. Wadsworth. 1987. Primary sequence and developmental expression of a novel Drosophila melanogaster src gene. Mol. Cell. Biol. 7:2119–2127.
  • Henkemeyer, M. J., F. B. Gertler, W. Goodman, and F. M. Hoffmann. 1987. The Drosophila Abelson proto-oncogene ho-molog: identification of mutant alleles that have pleiotropic effects late in development. Cell 51:821–828.
  • Hermans, A., N. Heisterkamp, M. von Lindern, S. van Baal, D. Meyer, D. van der Plas, L. M. Wiedemann, J. Groffen, D. Bootsma, and G. Grosveld. 1987. Unique fusion of bcr and c-abl genes in Philadelphia chromosome positive acute lymphoblastic leukemia. Cell 51:33–40.
  • Hirai, H., Y. Main, K. Hagiwara, J. Nishida, and F. Takaku. 1987. A novel putative tyrosine kinase receptor encoded by the eph gene. Science 238:1717–1720.
  • Hirohashi, S., Y. Shimosato, T. Kameya, K. Nagai, and R. Tsunematsu. 1977. Hormone dependency of a serially transplantable human breast cancer (Br-10) in nude mice. Cancer Res. 37:3184–3189.
  • Huang, C., C. Hammond, and J. M. Bishop. 1985. Nucleotide sequence and topography of chicken c-fps. Genesis of a retroviral oncogene encoding a tyrosine-specific protein kinase. J. Mol. Biol. 181:175–186.
  • Hunter, T. 1987. A thousand and one protein kinases. Cell 50:823–829.
  • Huynh, T. V., R. A. Young, and R. W. Davis. 1985. Constructing and screening cDNA libraries in lambda-GT 10 and lambda-GT 11, p. 49–78. In D. Grover (ed.), DNA cloning, vol. I. IRL Press, Oxford.
  • Ishii, S., F. Imamoto, Y. Yamanashi, K. Toyoshima, and T. Yamamoto. 1987. Characterization of the promoter region of the human c-erbB-2 protooncogene. Proc. Natl. Acad. Sci. USA 84:4374–4378.
  • James, R., and R. A. Bradshaw. 1984. Polypeptide growth factors. Annu. Rev. Biochem. 53:259–292.
  • Kanda, N., Y. Tsuchida, J. Hata, N. E. Kohl, F. W. Alt, S. A. Latt, and T. Utakoji. 1987. Amplification of IMR-32 clones 8, G21, and N-myc in human neuroblastoma xenografts. Cancer Res. 47:3291–3295.
  • Kawakami, T., C. Y. Pennington, and K. C. Robbins. 1986. Isolation and oncogenic potential of a novel human src-like gene. Mol. Cell. Biol. 6:4195–4201.
  • Koeffler, H. P., and D. W. Golde. 1978. Acute myelogenous leukemia: a human cell line responsive to colony-stimulating activity. Science 200:1153–1154.
  • Korc, M., P. Meltzer, and J. Trent. 1986. Enhanced expression of epidermal growth factor receptor correlates with alterations of chromosome 7 in human pancreatic cancer. Proc. Natl. Acad. Sci. USA 83:5141–5144.
  • Kraus, M. H., N. C. Popescu, S. C. Amsbaugh, and C. R. King. 1987. Overexpression of the EGF receptor-related proto-oncogene erbB-2 in human mammary tumor cell lines by different molecular mechanisms. EMBO J. 6:605–610.
  • Kruh, G. D., C. R. King, M. H. Kraus, N. C. Popescu, S. C. Amsbaugh, W. O. McBride, and S. A. Aaronson. 1986. A novel human gene closely related to the abl proto-oncogene. Science 234:1545–1548.
  • Libermann, T. A., H. R. Nusbaum, N. Razon, R. Kris, I. Lax, H. Soreq, N. Whittle, M. D. Waterfield, A. Ullrich, and J. Schlessinger. 1985. Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumors of glial origin. Nature (London) 313:144–147.
  • Lozzio, C. B., and B. B. Lozzio. 1975. Human chronic myelogenous leukemia cell-line with positive Philadelphia chromosome. Blood 45:321–334.
  • Marth, J. D., R. Peet, E. D. Krebs, and R. M. Perlmutter. 1985. A lymphocyte-specific protein-tyrosine kinase gene is rearranged and overexpressed in the murine T cell lymphoma LSTRA. Cell 43:393–404.
  • Martin-Zanca, D., S. H. Hughes, and M. Barbacid. 1986. A human oncogene formed by the fusion of truncated tropomyosin and protein tyrosine kinase sequences. Nature (London) 319:743–748.
  • Martin-Zanca, D., G. Mitra, L. K. Long, and M. Barbacid. 1986. Molecular characterization of the human trk oncogene. Cold Spring Harbor Symp. Quant. Biol. 51:983–992.
  • Matsushime, H., M. C. Yoshida, M. Sasaki, and M. Shibuya. 1987. A possible new member of tyrosine kinase family, human frt sequence, is highly conserved in vertebrates and located on human chromosome 13. Jpn. J. Cancer Res. (Gann) 78:655–661.
  • Messing, J. 1983. New M13 vectors for cloning. Methods Enzymol. 101:20–78.
  • Minowada, J., T. Ohnuma, and G. E. Moore. 1972. Rosette-forming human lymphoid cell lines. I. Establishment and evidence for origin of thymus-derived lymphocytes. J. Natl. Cancer Inst. 49:891–895.
  • Mori, T., S. Nakazawa, K. Nishino, K. Sugita, K. Takane, M. Mori, K. Sagawa, Y. Hayashi, and M. Sakurai. 1987. Ph1-positive CML-derived myeloid-monocytoid precursor cell line producing substances that stimulates normal CFU-C. Leukemia Res. 11:241–249.
  • Mount, S. M. 1982. A catalogue of splice junction sequences. Nucleic Acids Res. 10:459–472.
  • Neckameyer, W. S., M. Shibuya, M. Hsu, and L. Wang. 1986. Proto-oncogene c-ros codes for a molecule with structural features common to those of growth factor receptors and displays tissue-specific and developmentally regulated expression. Mol. Cell. Biol. 6:1478–1486.
  • Nishizawa, M., K. Semba, M. C. Yoshida, T. Yamamoto, M. Sasaki, and K. Toyoshima. 1986. Structure, expression, and chromosomal location of the human c-fgr gene. Mol. Cell. Biol. 6:511–517.
  • Ohta, M., Y. Fnrukawa, C. Ide, N. Akiyama, T. Utakoji, Y. Miura, and M. Saito. 1986. Establishment and characterization of four human monocytoid leukemia cell lines (JOSK-I, -S, -M, and -K) with capabilities of monocyte-macrophage lineage differentiation and constitutive production of interleukin 1. Cancer Res. 46:3067–3074.
  • Okabe, T., T. Kaizu, M. Fujisawa, J. Watanabe, K. Kojima, T. Yamashita, and F. Takaku. 1984. Monoclonal antibodies to surface antigens of small cell carcinoma of the lung. Cancer Res. 44:5273–5278.
  • Okabe, T., A. Urabe, T. Kato, S. Chiba, and F. Takaku. 1985. Production of erythropoietin-like activity by human renal and hepatic carcinomas in cell culture. Cancer 55:1918–1923.
  • Okabe, T., H. Nomura, and N. Oshawa. 1982. Establishment and characterization of a human colony-stimulating factor-producing cell line from a squamous cell carcinoma of the thyroid gland. JNCI 69:1235–1243.
  • Okabe, T., N. Yamaguchi, and N. Ohsawa. 1983. Establishment and characterization of a carcinoembryonic antigen (CEA)-producing cell line from a human carcinoma of the exocrine pancreas. Cancer 51:662–668.
  • Pollard, J. W., A. Bartocci, R. Arceci, A. Orlofsky, M. B. Ladner, and E. R. Stanley. 1987. Apparent role of the macrophage growth factor, CSF-1, in placental development. Nature (London) 330:484–486.
  • Quintrell, N., R. Lebo, H. Varmus, J. M. Bishop, M. J. Pette-nati, M. M. Le Beau, M. O. Diaz, and J. D. Rowley. 1987. Identification of a human gene (HCK) that encodes a protein-tyrosine kinase and is expressed in hemopoietic cells. Mol. Cell. Biol. 7:2267–2275.
  • Rettenmier, C. W., J. H. Chen, M. F. Roussel, and C. J. Sherr. 1985. The product of the c-fms proto-oncogene: a glycoprotein with associated tyrosine kinase activity. Science 228:320–322.
  • Rettenmier, C. W., R. Sacca, W. L. Furman, M. F. Roussel, J. T. Holt, A. W. Nienhuis, E. R. Stanley, and C. J. Sherr. 1986. Expression of the human c-fms proto-oncogene product (colony-stimulating factor-1 receptor) on peripheral blood mononuclear cells and choriocarcinoma cell lines. J. Clin. Invest. 77:1740–1746.
  • Riedel, H., J. Schlessinger, and A. Ullrich. 1987. A chimeric, ligand-binding v-erbB/EGF receptor retains transforming potential. Science 236:197–200.
  • Roebroek, A. J. M., J. A. Schalken, J. S. Verbeek, A. M. W. Van den Ouweland, C. Onnekink, H. P. J. Bloemers, and W. J. M. Van de Ven. 1985. The structure of the human c-fes/ fps proto-oncogene. EMBO J. 4:2897–2903.
  • Roussel, M. F., T. J. Dull, C. W. Rettenmier, P. Ralph, A. Ullrich, and C. J. Sherr. 1987. Transforming potential of the c-fms proto-oncogene (CSF-1 receptor). Nature (London) 325:549–552.
  • Sariban, E., T. Mitchell, and D. Kufe. 1985. Expression of the c-fms proto-oncogene during human monocytic differentiation. Nature (London) 316:64–66.
  • Schejter, E. D., D. Segal, L. Glazer, and B. Shilo. 1986. Alternative 5′ exons and tissue-specific expression of the Dro-sophila EGF receptor homolog transcripts. Cell 46:1091–1101.
  • Sekiguchi, M., K. Sasakibara, and G. Fujii. 1978. Establishment of cultured cell lines derived from a human gastric carcinoma. Jpn. J. Exp. Med. 48:61–68.
  • Semba, K., N. Kamata, K. Toyoshima, and T. Yamamoto. 1985. A v-erbB-related protooncogene, c-erbB-2, is distinct from the c-erbB-1/epidermal growth factor-receptor gene and is amplified in a human salivary gland adenocarcinoma. Proc. Natl. Acad. Sci. USA 82:6497–6501.
  • Semba, K., M. Nishizawa, N. Miyajima, M. C. Yoshida, J. Sukegawa, Y. Yamanashi, M. Sasaki, T. Yamamoto, and K. Toyoshima. 1986. yes-related proto-oncogene, syn, belongs to the protein tyrosine kinase family. Proc. Natl. Acad. Sci. USA 83:5459–5463.
  • Slamon, D. J., J. B. deKernion, I. M. Verma, and M. J. Cline. 1984. Expression of cellular oncogenes in human malignancies. Science 224:256–262.
  • Slamon, D. J., G. M. Clark, S. G. Wong, W. J. Levin, A. Ullrich, and W. L. McGuire. 1987. Human breast cancer: correlation of relapse and survival with amplification of the HER-2/ neu oncogene. Science 235:177–182.
  • Sundstrom, C., and K. Nilsson. 1976. Establishment and characterization of a human histiocytic lymphoma cell line (U-937). Int. J. Cancer 17:565–577.
  • Takahashi, M., and G. M. Cooper. 1987. ret transforming gene encodes a fusion protein homologous to tyrosine kinases. Mol. Cell. Biol. 7:1378–1385.
  • Takeya, T., and H. Hanafusa. 1983. Structure and sequence of the cellular gene homologous to the RSV src gene and the mechanism for generating the transforming virus. Cell 32:881–890.
  • Thomas, P. S. 1980. Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose. Proc. Natl. Acad. Sci. USA 77:5201–5205.
  • Toyoshima, K., K. Semba, T. Akiyama, S. Ikawa, and T. Yamamoto. 1986. The c-erbB-2 gene encodes a receptor-like protein with tyrosine kinase activity. Cold Spring Harbor Symp. Quant. Biol. 51:977–982.
  • Ullrich, A., L. Coussens, J. S. Hayflick, T. J. Dull, A. Gray, A. W. Tarn, J. Lee, Y. Yarden, T. A. Libermann, J. Schlessinger, J. Downward, E. L. V. Mayes, N. Whittle, M. D. Water-field, and P. H. Seeburg. 1984. Human epidermal growth factor receptor cDN A sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells. Nature (London) 309:418–425.
  • Ullrich, A., J. R. Bell, E. Y. Chen, R. Herrera, L. M. Petruzzelli, T. J. Dull, A. Gray, L. Coussens, Y.-C. Liao, M. Tsubokawa, A. Mason, P. H. Seeburg, C. Grunfeld, O. M. Rosen, and J. Rama-chandran. 1985. Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes. Nature (London) 313:756–761.
  • Ullrich, A., H. Riedel, Y. Yarden, L. Coussens, A. Gray, T. Dull, J. Schlessinger, M. D. Waterfield, and P. J. Parker. 1986. Protein kinases in cellular signal transduction: tyrosine kinase growth factor receptors and protein kinase C. Cold Spring Harbor Symp. Quant. Biol. 51:713–724.
  • Verbeek, J. S., A. J. M. Roebroek, A. M. W. Van den Ouweland, H. P. J. Bloemers, and W. J. M. Van de Ven. 1985. Human c-fms proto-oncogene: comparative analysis with an abnormal allele. Mol. Cell. Biol. 5:422–426.
  • Yamanashi, Y., S. Fukushige, K. Semba, J. Sukegawa, N. Miyajima, K. Matsubara, T. Yamamoto, and K. Toyoshima. 1987. The yes-related cellular gene lyn encodes a possible tyrosine kinase similar to p56lck. Mol. Cell. Biol. 7:237–243.
  • Yoshida, M. C., T. Ikeuchi, and M. Sasaki. 1975. Differential staining of parental chromosomes in interspecific cell hybrids with a combined quinacrine and 33258 Hoechst technique. Proc. Jpn. Acad. 51:184–187.
  • Ziegler, S. F., J. M. Marth, D. B. Lewis, and R. M. Perlmutter. 1987. Novel protein-tyrosine kinase gene (hck) preferentially expressed in cells of hematopoietic origin. Mol. Cell. Biol. 7:2276–2285.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.