1
Views
4
CrossRef citations to date
0
Altmetric
Gene Expression

Hormonal Regulation of Phosphoenolpyruvate Carboxykinase Gene Expression Is Mediated through Modulation of an Already Disrupted Chromatin Structure

, &
Pages 1289-1297 | Received 12 Sep 1988, Accepted 16 Dec 1988, Published online: 31 Mar 2023

LITERATURE CITED

  • Allegra, P., Sterner R., Clayton D. F., and Allfrey V. G.. 1987. Affinity chromatographic purification of nucleosomes containing transcriptionally active DNA sequences. J. Mol. Biol. 196:379–388.
  • Beale, E. G., Chrapkiewicz N. B., Scoble H. A., Metz R. J., Quick D. P., Noble R. L., Donelson J. E., Biemann K., and Granner D. K.. 1989. Rat hepatic cytosolic phosphoenolpyruvate car-boxykinase: structures of the protein, messenger RNA and gene. J. Biol. Chem. 260:10748–10760.
  • Becker, P. B., Ruppert S., and Schutz G.. 1987. Genomic footprinting reveals cell type-specific DNA binding of ubiquitous factors. Cell 51:435–443.
  • Bellard, M., Dretzen G., Bellard F., Oudet P., and Chambon P.. 1982. Disruption of the typical chromatin structure in a 2500 basepair region at the 5′ end of the actively transcribed ovalbumin gene. EMBO J. 1:223–230.
  • Bevenisty, N., Mencher D., Meyuhas O., Razin A., and Reshef L.. 1989. Sequential changes in DNA methylation patterns of the rat phosphoenolpyruvate carboxykinase gene during development. Proc. Natl. Acad. Sci. USA 82:267–271.
  • Burch, J. B. E., and Weintraub H.. 1983. Temporal order of chromatin structural changes associated with activation of the chicken vitellogenin gene. Cell 33:65–76.
  • Cartwright, I. L., and Elgin S. C. R.. 1986. Nucleosomal instability and induction of new upstream protein-DNA association accompany activation of four small heat shock protein genes in Drosophila melanogaster. Mol. Cell. Biol. 6:779–791.
  • Cedar, H.. 1988. DNA methylation and gene activity. Cell 53:3–4.
  • Cochet-Meilhac, M., Nuret P., Courvalin J. C., and Chambon P.. 1974. Animal DNA-dependent RNA polymerases: determination of the cellular number of RNA polymerase B molecules. Biochim. Biophys. Acta 353:185–192.
  • Cohen, R. B., and Sheffery M.. 1989. Nucleosome disruption precedes transcription and is largely limited to the transcribed domain of globin genes in murine erythroleukemia cells. J. Mol. Biol. 182:109–129.
  • Doerfler, W.. 1983. DNA methylation and gene activity. Annu. Rev. Biochem. 52:93–124.
  • Eissenberg, J. C, Cartwright I. L., Thomas G. H., and Elgin S. C. R.. 1989. Selected topics in chromatin structure. Annu. Rev. Genet. 19:485–536.
  • Emerson, B. M., Lewis L. D., and Felsenfeld G.. 1989. Interaction of specific nuclear factors with the nuclease-hypersensitive region of the chicken adult β-globin gene: the nature of the binding domain. Cell 41:21–30.
  • Feinberg, A. P., and Vogelstein B.. 1983. A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal. Biochem. 132:6–13.
  • Garel, A., and Axel R.. 1976. Selective digestion of transcriptionally active ovalbumin genes from oviduct nuclei. Proc. Natl. Acad. Sci. USA 73:3966–3970.
  • Garel, A., Zolan M., and Axel R.. 1977. Genes transcribed at diverse rates have a similar conformation in chromatin. Proc. Natl. Acad. Sci. USA 74:4867–4871.
  • Gross, D. S., and Garrard W. T.. 1988. Nuclease hypersensitive sites in chromatin. Annu. Rev. Biochem. 57:159–197.
  • Hebbes, T. R., Thorne A. W., and Crane-Robinson C.. 1988. A direct link between core histone acetylation and transcriptionally active chromatin. EMBO J. 7:1395–1402.
  • Hemenway, C., and Robins D. M.. 1987. DNase I-hypersensitive sites associated with expression and hormonal regulation of mouse C4 and SIP gene. Proc. Natl. Acad. Sci. USA 84: 4816–4820.
  • Jackson, P. D., and Felsenfeld G.. 1989. A method for intranuclear footprinting and its application to a nuclease hypersensitive site in chromatin. Proc. Natl. Acad. Sci. USA 82:2296–2300.
  • Keene, M. A., Corces V., Lowenhaupt K., and Elgin S. C. R.. 1981. DNase I hypersensitive sites in Drosophila chromatin at the 5′ end of regions of transcription. Proc. Natl. Acad. Sci. USA 78:143–146.
  • Levy-Wilson, B., Fortier C., Blackhart B. D., and McCarthy B. J.. 1988. DNase I and micrococcal nuclease-hypersensitive sites in the human apolipoprotein B gene are tissue specific. Mol. Cell. Biol. 8:71–80.
  • Magnuson, M. A., Quinn P. G., and Granner D. K.. 1987. Multihormonal regulation of phosphoenolpyruvate carboxyki-nase-chloramphenicol acetyltransferase fusion gene: insulin's effects oppose those of cAMP and dexamethasone. J. Biol. Chem. 262:14917–14920.
  • Maniatis, T., Fritsch E. F., and Sam brook J.. 1982. Molecular cloning: a laboratory manual, p. 458–462. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
  • McGinnis, W., Shermoen A. W., Heemskerk J., and Beckendorf S. K.. 1983. DNA sequence changes in an upstream DNase I-hypersensitive region are correlated with reduced gene expression. Proc. Natl. Acad. Sci. USA 80:1063–1067.
  • Nahon, J.-L., Venetianer A., and Sala-Trepat J. M.. 1987. Specific sets of DNase I-hypersensitive sites are associated with the potential and overt expression of rat albumin and α-fetal-protein genes. Proc. Natl. Acad. Sci. USA 84:2135–2139.
  • Palen, T. E., and Cech T. R.. 1984. Chromatin structure at the Vol. 9, 1989 replication origin and transcription initiation regions of the ribosomal genes of Tetrahymena. Cell 36:933–942.
  • Parslow, T. G., and Granner D. K.. 1982. Chromatin changes accompany immunoglobulin κ gene activation: a potential control region within the gene. Nature (London) 299:449–451.
  • Pederson, D. S., Thoma F., and Simpson R. T.. 1986. Core particle, fiber and transcriptionally active chromatin structure. Annu. Rev. Cell Biol. 2:117–147.
  • Petersen, D. D., Magnuson M. A., and Granner D. K.. 1988. Location and characterization of two widely separated glucocorticoid response elements in the phosphoenolpyruvate car-boxykinase gene. Mol. Cell. Biol. 8:96–104.
  • Piette, I., Kryszke M.-H., and Yanif M.. 1989. Specific interaction of cellular factors with the B enhancer of polyoma virus. EMBO J. 4:2675–2685.
  • Plesko, M. M., Hargrove J. L., Granner D. K., and Chalkley R.. 1983. Inhibition by sodium butyrate of enzyme induction by glucocorticoids and dibutyryl cyclic AMP: a role for the rapid form of histone acetylation. J. Biol. Chem. 258:13738–13744.
  • Quinn, P. G., Wong T. W., Magnuson M. A., Shabb J. B., and Granner D. K.. 1988. Identification of basal and cyclic AMP regulatory elements in the promoter of the phosphoenolpyruvate carboxykinase gene. Mol. Cell. Biol. 8:3467–3475.
  • Rasmussen, J. A., and Gilboa E.. 1987. Significance of DNase I-hypersensitive sites in the long terminal repeats of a Moloney murine leukemia virus vector. J. Virol. 61:1368–1374.
  • Richard-Foy, H., and Hager G. L.. 1987. Sequence-specific positioning of nucleosomes over the steroid-inducible MMTV promoter. EMBO J. 6:2321–2328.
  • Rocha, E., Davie J. R., van Holde K. E., and Weintraub H.. 1984. Differential salt fractionation of active and inactive genomic domains in chicken erythrocyte. J. Biol. Chem. 259: 8558–8563.
  • Rose, S. M., and Garrard W.. 1984. Differentiation-dependent chromatin alterations precede transcription of immunoglobulin light chain genes. J. Biol. Chem. 259:8534–8544.
  • Sasaki, K., Cripe T. P., Koch S. R., Andreone T. L., Petersen D. D., Beale E. G., and Granner D. K.. 1984. Multihormonal regulation of phosphoenolpyruvate carboxykinase gene transcription: the dominant role of insulin. J. Biol. Chem. 259: 15242–15251.
  • Sasaki, K., and Granner D. K.. 1988. Regulation of phosphoenolpyruvate carboxykinase gene transcription by insulin and cAMP: reciprocal actions on initiation and elongation. Proc. Natl. Acad. Sci. USA 85:2954–2958.
  • Sun, Y. L., Xu Y. Z., Bellard M., and Chambon P.. 1986. Digestion of the chicken β-globin gene chromatin with micro-coccal nuclease reveals the presence of an altered nucleosomal array characterized by an atypical ladder of DNA fragments. EMBO J. 5:293–300.
  • Thoma, F.. 1986. Protein-DNA interaction and nuclease sensitive regions determine nucleosome positions on yeast plasmid chromatin. J. Mol. Biol. 190:177–190.
  • Villeponteau, B., Lundell M., and Martinson H.. 1984. Torsional stress promotes the DNase I sensitivity of active genes. Cell 39:469–478.
  • Weintraub, H., and Groudine M.. 1976. Chromosomal subunits in active genes have an altered conformation. Science 193: 848–858.
  • Wynshaw-Boris, A., Lugo T. G., Short J. M., Fournier R. E. K., and Hanson R. W.. 1984. Identification of a cAMP regulatory region in the gene for rat cytosolic phosphoenolpyruvate carboxykinase: use of chimeric genes transfected into hepatoma cells. J. Biol. Chem. 259:12161–12169.
  • Zaret, K. S., and Yamamoto K. R.. 1984. Reversible and persistent changes in chromatin structure accompany activation of a glucocorticoid-dependent enhancer element. Cell 38:29–38.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.