7
Views
6
CrossRef citations to date
0
Altmetric
Gene Expression

Purification and Characterization of Multiple Nuclear Factors That Bind to the TAX-Inducible Enhancer within the Human T-Cell Leukemia Virus Type 1 Long Terminal Repeat

, &
Pages 1733-1745 | Received 05 Nov 1988, Accepted 18 Jan 1989, Published online: 31 Mar 2023

LITERATURE CITED

  • Altman, R., D. Harrich, J. A. Garcia, and R. B. Gaynor. 1988. Human T-cell leukemia virus types I and II exhibit different DNase I protection patterns. J. Virol. 62:1339–1346.
  • Arya, S.. 1988. Human and simian immunodeficiency retroviruses: activation and differential transactivation of gene expression. AIDS Res. Human Retroviruses 4:175–186.
  • Bradford, M. M.. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:248–254.
  • Brady, J., K.-T. Jeang, J. Duvall, and G. Khoury. 1987. Identification of p40x-responsive regulatory sequences within the human T-cell leukemia virus type I long terminal repeat. J. Virol. 61:2175–2181.
  • Comb, M., N. C. Birnberg, A. Seasholtz, E. Herbert, and H. M. Goodman. 1986. A cyclic AMP- and phorbol ester-inducible DNA element. Nature (London) 323:353–356.
  • Cross, S. L., M. B. Feinberg, J. B. Wolf, N. J. Holbrook, F. Wong-Staal, and W. J. Leonard. 1987. Regulation of the human interleukin-2 receptor alpha chain promoter: activation of a nonfunctional promoter by the transactivator gene of HTLV-I. Cell 49:47–56.
  • Dignam, J. D., R. Lebovitz, and R. G. Roeder. 1983. Accurate transcription initiation by polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res. 11:1475–1489.
  • DucDodon, M., and L. Gazzolo. 1987. Loss of interleukin-2 requirement for the generation of T colonies defines an early event of human T-lymphotropic virus type 1 infection. Blood 69:12–17.
  • Faller, D. V., M. A. V. Crimmins, and S. J. Mentzer. 1988. Human T-cell leukemia virus type 1 infection of CD4+ or CD8+ cytotoxic T-cell clones results in immortalization with retention of antigen specificity. J. Virol. 62:2942–2950.
  • Felber, B. K., H. Paskalis, C. Kleinman-Ewing, F. Wong-Staal, and G. N. Pavlakis. 1985. The pX protein of HTLV-I is a transcriptional activator of its long terminal repeats. Science 229:675–679.
  • Fisch, T. M., R. Prywes, and R. G. Roeder. 1987. c-fos sequences necessary for basal expression and induction by epidermal growth factor, 12-O-tetradecanoylphorbol-13-acetate, and the calcium ionophore. Mol. Cell. Biol. 7:3490–3502.
  • Fried, M., and D. M. Crothers. 1981. Equilibrium and kinetics of lac repressor-operator interactions by polyacrylamide gel electrophoresis. Nucleic Acids Res. 9:6505–6525.
  • Fujisawa, J.-L., M. Seiki, M. Sato, and M. Yoshida. 1986. A transcriptional enhancer sequence of HTLV-I is responsible for trans-activation mediated by p40× of HTLV-I. EMBO J. 5:713–718.
  • Gallo, R., F. Wong-Staal, L. Montagnier, W. A. Haseltine, and M. Yoshida. 1988. HIV/HTLV gene nomenclature. Nature (London) 333:504.
  • Garner, M. M., and A. Revzin. 1981. A gel electrophoresis method for quantifying binding of proteins to specific DNA regions: applications to components of the Escherichia coli lactose operon regulatory system. Nucleic Acids Res. 9:3047–3060.
  • Gazzolo, L., and M. Duc Dodon. 1987. Direct activation of resting T lymphocytes by human T-lymphotropic virus type I. Nature (London) 326:714–717.
  • Goh, W. C., J. Sodroski, C. Rosen, M. Essex, and W. A. Haseltine. 1985. Subcellular localization of the product of the long open reading frame of human T-cell leukemia virus type I. Science 227:1227–1228.
  • Gorman, C. M., L. F. Moffat, and B. H. Howard. 1982. Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells. Mol. Cell. Biol. 2:1044–1051.
  • Hager, D. A., and R. R. Burgess. 1980. Elution of proteins from SDS polyacrylamide gels, removal of sodium dodecyl sulfate and renaturation of enzymatic activity. Anal. Biochem. 109:76–86.
  • Hai, T., F. Liu, E. A. Allegretto, M. Karin, and M. R. Green. 1988. A family of immunologically related transcription factors that includes multiple forms of ATF and AP-1. Genes & Dev. 2:1216–1226.
  • Hardy, S., and T. Shenk. 1988. Adenoviral control regions activated by E1A and cAMP response element bind to the same factor. Proc. Natl. Acad. Sci. USA 85:4171–4175.
  • Horikoshi, M., T. Hai, Y.-S. Lin, M. R. Green, and R. G. Roeder. 1988. Transcription factor ATF interacts with the TATA factor to facilitate establishment of a preinitiation complex. Cell 54:1033–1042.
  • Inoue, J.-L., M. Seiki, T. Taniguchi, S. Tsuru, and M. Yoshida. 1986. Induction of interleukin 2 receptor gene expression by p40× encoded by human T-cell leukemia virus type 1. EMBO J. 5:2883–2888.
  • Jacobson, S., C. S. Raine, E. S. Mingioli, and D. E. McFarlin. 1988. Isolation of an HTLV-1-like retrovirus from patients with tropical spastic paraparesis. Nature (London) 331:540–543.
  • Jeang, K.-T., I. Boros, J. Brady, M. Radonovich, and G. Khoury. 1988. Characterization of cellular factors that interact with the human T-cell leukemia virus type I p40×-responsive 21-base-pair sequence. J. Virol. 62:4499–4509.
  • Josephs, S. F., F. Wong-Staal, V. Manzari, R. C. Gallo, J. G. Sodroski, M. D. Trus, D. Perkins, R. Patarca, and W. A. Haseltine. 1984. Long terminal repeat structure of an American isolate of type 1 human T-cell leukemia virus. Virology 139:340–345.
  • Kadonaga, J. T., and R. Tjian. 1986. Affinity purification of sequence-specific DNA binding proteins. Proc. Natl. Acad. Sci. USA 83:5889–5893.
  • Laemmli, U. K.. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (London) 227:680–685.
  • Lee, K. A. W., T.-Y. Hai, L. SivaRaman, B. Thimmappaya, H. C. Hurst, N. C. Jones, and M. R. Green. 1987. A cellular protein activating transcription factor activates transcription of multiple E1a-inducible adenovirus early promoters. Proc. Natl. Acad. Sci. USA 84:8355–8359.
  • Lee, T. H., J. E. Coligan, J. G. Sodroski, W. A. Haseltine, S. Z. Salahuddin, F. Wong-Staal, R. C. Gallo, and M. Essex. 1984. Antigens encoded by the 3′-terminal region of human T-cell leukemia virus: evidence for a functional gene. Science 226:57–61.
  • Leung, K., and G. J. Nabel. 1988. HTLV-I transactivator induces interleukin-2 receptor expression through an NF-kB- like factor. Nature (London) 333:776–778.
  • Lin, Y.-S., and M. R. Green. 1988. Interaction of a common cellular transcription factor, ATF, with regulatory elements in both E1a- and cyclic AMP-inducible promoters. Proc. Natl. Acad. Sci. USA 85:3396–3400.
  • Mann, D. L., P. DeSantis, G. Mark, A. Pfeifer, M. Newman, N. Gibbs, M. Popovic, M. G. Sarngaharan, R. C. Gallo, J. Clark, and W. Blattner. 1987. HTLV-I associated B-cell CLL: indirect role for retrovirus in leukemogenesis. Science 236:1103–1106.
  • Maruyama, M., H. Shibuya, H. Harada, M. Hatakeyama, M. Seiki, T. Fujita, J.-I. Inoue, M. Yoshida, and T. Taniguchi. 1987. Evidence for aberrant activation of the interleukin-2 autocrine loop by HTLV-l-encoded p40× and T3/Ti complex triggering. Cell 48:343–350.
  • Miyatake, S., M. Seiki, R. D. Malefijt, T. Heike, J.-I. Fujisawa, Y. Takebe, J. Nishida, J. Shlomai, T. Yokota, K.-I. Arai, and N. Arai. 1988. Activation of T cell-derived lymphokine genes in T cells and fibroblasts: effects of human T cell leukemia virus type I p40× protein and bovine papilloma virus encoded E2 protein. Nucleic Acids Res. 16:6547–6566.
  • Miyatake, S., M. Seiki, M. Yoshida, and K.-I. Arai. 1988. T-cell activation signals and human T-cell leukemia virus type I- encoded p40× protein activate the mouse granulocyte-macrophage colony-stimulating factor gene through a common DNA element. Mol. Cell. Biol. 8:5581–5587.
  • Montminy, M. R., K. A. Sevarino, J. A. Wagner, G. Mandel, and R. H. Goodman. 1986. Identification of a cyclic-AMP- responsive element within the rat somatostatin gene. Proc. Natl. Acad. Sci. USA 83:6682–6686.
  • Nakajima, N., M. Horikoshi, and R. G. Roeder. 1988. Factors involved in specific transcription by mammalian RNA polymerase II: purification, genetic specificity, and TATA box-promoter interactions of TFIID. Mol. Cell. Biol. 8:4028–4040.
  • Nerenberg, M., S. H. Hinrichs, R. K. Reynolds, G. Khoury, and G. Jay. 1987. The tat gene of human T-lymphotropic virus type I induces mesenchymal tumors in transgenic mice. Science 237:1324–1329.
  • Nyborg, J. K., W. S. Dynan, I. S. Y. Chen, and W. Wachsman. 1988. Binding of host-cell factors to DNA sequences in the long terminal repeat of human T-cell leukemia virus type I: implications for viral gene expression. Proc. Natl. Acad. Sci. USA 85:1457–1461.
  • Ohtani, K., M. Nakamura, S. Saito, T. Noda, Y. Ito, K. Sugamura, and Y. Hinuma. 1987. Identification of two distinct elements in the long terminal repeat of HTLV-I responsible for maximum gene expression. EMBO J. 6:389–395.
  • Paskalis, H., B. K. Felber, and G. N. Pavlakis. 1986. Cis-acting sequences responsible for the transcriptional activation of human T-cell leukemia virus type I constitute a conditional enhancer. Proc. Natl. Acad. Sci. USA 83:6558–6562.
  • Popovic, M., G. Lange-Wantzin, P. S. Sarin, D. Mann, and R. C. Gallo. 1983. Transformation of human umbilical cord blood T cells by human T-cell leukemia/lymphoma virus. Proc. Natl. Acad. Sci. USA 80:5402–5406.
  • Reddy, E. P., R. V. Mettus, E. DeFreitas, Z. Wroblewska, M. Cisco, and H. Koprowski. 1988. Molecular cloning of human T-cell lymphotropic virus type I-like proviral genome from the peripheral lymphocyte DNA of a patient with chronic neurologic disorders. Proc. Natl. Acad. Sci. USA 85:3599–3603.
  • Rosen, C. A., R. Park, J. G. Sodroski, and W. A. Haseltine. 1987. Multiple sequence elements are required for regulation of human T-cell leukemia virus gene expression. Proc. Natl. Acad. Sci. USA 84:4919–4923.
  • Rosen, C. A., J. G. Sodroski, and W. A. Haseltine. 1985. Location of cis-acting regulatory sequences in the human T-cell leukemia virus type I long terminal repeat. Proc. Natl. Acad. Sci. USA 82:6502–6506.
  • Rosenfeld, P. J., and T. J. Kelly. 1986. Purification of nuclear factor 1 by DNA recognition site affinity chromatography. J. Biol. Chem. 281:1398–1408.
  • Ruben, S., H. Poteat, T.-H. Tan, K. Kawakami, R. Roeder, W. Haseltine, and C. A. Rosen. 1988. Cellular transcription factors and regulation of IL-2 receptor gene expression by HTLV-I tax gene product. Science 241:89–92.
  • Saito, S., M. Nakamura, K. Ohtani, M. Ichijo, K. Sugamura, and Y. Hinuma. 1988. trans-Activation of the simian virus 40 enhancer by a pX product of human T-cell leukemia virus type and I. J. Virol. 62:644–648.
  • Seiki, M., J.-I. Inoue, T. Takeda, and M. Yoshida. 1986. Direct evidence that p40× of human T-cell leukemia virus type I is a trans-acting transcriptional activator. EMBO J. 5:561–565.
  • Shimotohno, K., M. Takano, T. Teruuchi, and M. Miwa. 1986. Requirement of multiple copies of a 21-nucleotide sequence in the U3 regions of human T-cell leukemia virus type I and type II long terminal repeats for trans-acting activation of transcription. Proc. Natl. Acad. Sci. USA 83:8112–8116..
  • Siekevitz, M., M. B. Feinberg, N. Holbrook, F. Wong-Staal, and W. C. Greene. 1987. Activation of interleukin 2 and interleukin 2 receptor (Tac) promoter expression by the trans-activator (tat) gene product of human T-cell leukemia virus, type I. Proc. Natl. Acad. Sci. USA 84:5389–5393.
  • Siekevitz, M., S. F. Josephs, M. Dukovich, N. Peffer, F. Wong-Staal, and W. C. Greene. 1987. Activation of the HIV-1 LTR by T cell mitogens and the trans-activator protein of HTLV-I. Science 238:1575–1578.
  • Slamon, D. J., W. J. Boyle, D. E. Keith, M. F. Press, D. W. Golde, and L. M. Souza. 1988. Subcellular localization of the trans-activating protein of human T-cell leukemia virus type and I. J. Virol. 62:680–686.
  • Slamon, D. J., K. Shimotohno, M. J. Cline, D. W. Golde, and I. S. Y. Chen. 1984. Identification of the putative transforming protein of the human T-cell leukemia viruses HTLV-I and HTLV-II. Science 226:61–65.
  • Sodroski, J., C. Rosen, W. C. Goh, and W. Haseltine. 1985. A transcriptional activator protein encoded by the x-lor region of the human T-cell leukemia virus. Science 228:1430–1434.
  • Sodroski, J., C. Rosen, and W. Haseltine. 1984. Trans-acting transcriptional activation of the long terminal repeat of human T lymphotropic virus in infected cells. Science 225:381–385.
  • Tan, T.-H., J. Wallis, and A. J. Levine. 1986. Identification of the p53 protein domain involved in formation of the simian virus 40 large T-antigen-p53 protein complex. J. Virol. 59:574–583.
  • Tsujimoto, A., T. Teruuchi, J. Imamura, K. Shimotohno, I. Miyoshi, and M. Miwa. 1988. Nucleotide sequence analysis of a provirus derived from HTLV-I-associated myelopathy (HAM). Mol. Biol. Med. 5:29–42.
  • Wong-Staal, F., and R. C. Gallo. 1985. Human T-lymphotropic retroviruses. Nature (London) 317:395–403.
  • Yamamoto, K. K., G. A. Gonzalez, W. H. Biggs, and M. R. Montminy. 1988. Phosphorylation-induced binding and transcriptional efficacy of nuclear factor CREB. Nature (London) 334:494–498.
  • Yamamoto, N., and Y. Hinuma. 1985. Viral aetiology of adult T-cell leukemia. J. Gen. Virol. 66:1641–1660.
  • Yamamoto, N., M. Okada, Y. Koyanagi, M. Kannagi, and Y. Hinuma. 1982. Transformation of human leukocytes by cocultivation with an adult T cell leukemia virus producer cell line. Science 217:737–739.
  • Yoshida, M.. 1987. Expression of the HTLV-1 genome and its association with a unique T-cell malignancy. Biochim. Biophys. Acta 907:145–161.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.