A contemporary overview of peripheral nerve research from the Cleveland Clinic Microsurgery Laboratory

REFERENCES

• Thomas PK, Berthold CH, Ochoa J. Microsurgical anatomy of the peripheral nervous system. In: Dyck PJ, Thomas PK, eds, Peripheral neuropathy, Ph iladelphia: W.B . Saunders, 1993: pp. 28–91
   Google Scholar
• Sunderland S. The anatomy and physiology of nerve injury. Muscle Nerve 1990: 13: 771–784
   PubMed Web of Science ®Google Scholar
• Maggi SP, Lowe III JB, Mackinnon SE. Pathophysiology of nerve injury. Clin Plast Surg 2003; 30:109-126
   Google Scholar
• Waller A. Experiments on the glossopharyngeal and hypoglossal nerves of the frog and observations produced thereby in the struc-ture of their primitive fibers. Phil Trans R Soc London 1850; 140: 423
   Google Scholar
• Lassner F, Schaller E, Steinhoff G, et al. Cellular mechanisms of rejection and regeneration in peripheral nerve allografts. Transplantation 1989; 48: 386–392
   PubMed Web of Science ®Google Scholar
• Yu LT, Hickey WF, Silvers WK, et al. Expression of class II antigens on peripheral nerve allografts. Ann NY Acad Sci 1988; 540: 472–474
   PubMedGoogle Scholar
• Sunderland S. A classification of peripheral nerve injuries producing loss of function. Brain 1951; 74:491
   PubMed Web of Science ®Google Scholar
• Mackinnon SE. New directions in peripheral nerve surgery. Ann Plast Surg 1989; 22: 257–273
   PubMed Web of Science ®Google Scholar
• Dahlin LB, Lundborg G. Use of tubes in peripheral nerve repair. Neurosurg Clin N Am 2001; 12: 341–352
   PubMed Web of Science ®Google Scholar
• Dvali L, Mackinnon S. Nerve repair, grafting, and nerve transfers. Clin Plast Surg 2003; 30: 203-221
   Google Scholar
• Harris ME, Tindall SC. Techniques of peripheral nerve repair. Neurosurg Clin N Am. 1991; 2:93–104
   PubMedGoogle Scholar
• Siemionow M, Tetik C, Ozer K, Ayhan S, Siemionow K, Browne E. Epineural sleeve neurorrhapy: Surgical technique and functional results: A preliminary report. Ann Plast Surg 2002; 48:281-285
   Google Scholar
• Tetik C, Ozer K, Ayhan S, Siemionow K, Browne E, Siemionow M. Conventional versus epineural sleeve neurorraphy technique: Functional and histomorphometric analysis. Ann Plast Surg 2002; 49: 397–403
   PubMed Web of Science ®Google Scholar
• Demirkan F, Snyder CC, Latifoglu O, Siemionow M. A method of enhancing regeneration of conventionally repaired peripheral nerves. Ann Plast Surg 1995; 34: 67–72
   PubMed Web of Science ®Google Scholar
• Cajal RS. Degeneration and regeneration of nervous system, Vol. 1, London: Oxford University Press, 1928
   Google Scholar
• Kuffler DF. Promoting and directing axon outgrowth. Mol Neurobiol 1994; 9: 233–243
   PubMed Web of Science ®Google Scholar
• Lundborg G. Nerve repair, current concepts and future prospectives. I Hand Ther 1999; 4: 5–7
   Google Scholar
• Vernadakis AJ, Koch H, Mackinnon SE. Managementof neuromas. Clin Plast Surg 2003; 30: 247-268
   Google Scholar
• Lundborg G, Rosen B, Dahlin L, Danielsen N, Holmberg J. Tubular versus conventional repair of median and ulnar nerves in the human forearm: Early results from a prospective randomized study. J Hand Surg (Am) 1997; 22: 1–8
   PubMedGoogle Scholar
• Dahlin LB, Anagnostaki L, Lundborg. Tissue response to silicone tubes used to repair human median and ulnar nerves. Scand J Plast Reconstr Surg Hand Surg2001; 35: 29-34.
   Google Scholar
• Mackinnon SE, Dellon AL. Clinical nerve reconstruction with a bioabsorbable polyglycolic acid tube. Plast Reconstr Surg 1990; 85: 419–424
   PubMed Web of Science ®Google Scholar
• Stensaas L, Bloch LM, Garcia R, Sotelo J Jr. Snug tubular enclosures reduce extrafascicular axonal escape at peripheral nerve repair sites. Exp Neurol. 1989; 103: 135–145
   PubMed Web of Science ®Google Scholar
• Strauch B. Use of nerve conduits in peripheral nerve repair. Hand Clin. 2000; 16: 123–130
   PubMed Web of Science ®Google Scholar
• Danielsson PA, Adolfsson L, Dahlin LB. Different effect on axonal outgrowth of application of non-absorbable or absorbable tubes around a nerve repair. ScandJ Plast ReconstrSurg Hand Surg. 2001; 35: 347–353.
   PubMed Web of Science ®Google Scholar
• Chiu DT, Strauch B. A prospective clinical evaluation of auto-genous vein grafts used as a nerve conduit for distal sensory nerve defects of 3 cm or less. Plast Reconstr Surg 1990; 86: 928–934
   PubMed Web of Science ®Google Scholar
• Chen LE, Seaber AV, Urban iak JR, et al. Denaturated muscle as a nerve conduit: A functional, morphologic, and electrophysio logic evaluation . J Reconstr Microsurg 1994; 10: 137–144
   PubMed Web of Science ®Google Scholar
• Lundborg G, Hasson HA. Nerve regeneration through preformed pseudosynov ia I tubes. J Hand Surg 1980; 5: 35–39
   PubMedGoogle Scholar
• Atabay K, Hong C, Heil BV, et al. The use of ‘Sliding epineural sheath tube’ for repair of peripheral nerve defects. Plastic Surgical Forum 1995; 18:121–123
   Google Scholar
• Ayhan S, Yavuzer R, Latifoglu O, et al. Use of the turnover ep ineura I sheath tube for repair of peripheral nerve gaps. I Reconstr Microsurg. 2000; 16: 371–377
   PubMed Web of Science ®Google Scholar
• Yavuzer R, Ayhan S, Latifoglu O, Atabay K. Turnover epineural sheath tube in primary repair of peripheral nerves. Ann Plast Surg 2002; 48: 392–400
   PubMed Web of Science ®Google Scholar
• Snyder CC, Browne EZ, Herzog BG, et al. Epineural cuff neu rorrhaphy. J Bone ft Surg Am. 1974; 56A: 1092
   Google Scholar
• Snyder CC. Epineural repair. Orthop Clin N Am 1981; 12:267–276
   PubMedGoogle Scholar
• Martini A, Fromm B. A new operation for the prevention and treatment of amputation neuromas. I Bone ft Surg Br 1989; 71: 379-3 82
   Google Scholar
• Lundborg G, Longo FM, Varon S. Nerve regeneration model and troph ic factors in vivo. Brain Res 1982; 232: 157–161
   PubMed Web of Science ®Google Scholar
• Longo FM, Manthorpe M, Skaper SD, et al. Neuronotrophic activities accumulate in vivo within silicone nerve regeneration chambers. Brain Res 1983; 261: 109–117
   PubMed Web of Science ®Google Scholar
• Bates DJ, Ranford JA, Mangelsdorf DC. Blot and culture analysis of neurotrophic factors in nerve regeneration chamber fluids. Neurochem Res 1991; 16: 621–628
   PubMed Web of Science ®Google Scholar
• Terenghi G. Peripheral nerve regeneration and neurotrophic factors. J Anat 1999; 194:1–14
   PubMed Web of Science ®Google Scholar
• Weisenhorn DM, Roback J, Young AN, et al. Cellular aspects of trophic actions in the nervous system. Int Rev Cytol 1999; 189: 177–265
   PubMedGoogle Scholar
• Meirer R, Gurunluoglu R, Siemionow M. Neurogenic perspective on vascular endothelial growth factor: Review of the literature. Reconstr Microsurg 2001; 17: 625–629
   PubMed Web of Science ®Google Scholar
• Samii A, Unger J, Lange W. Vascular endothelial growth factor expression in peripheral nerves and dorsal root ganglia in diabetic neuropathy in rats. Neurosci Lett 1999; 12: 159–162
   Google Scholar
• Gudemez E, Ozer K, Cunnigham B, Siemionow K, Browne E, Siemionow M. Dehydroepiandrosterone as an enhancer of functional recovery following crush injury to rat sciatic nerve. Microsurg 2002; 22:234-241
   Google Scholar
• Lohman R, Yowell R, Barton S, Araneo B, Siemionow M. Dehydroepiandrosterone protects muscle flap microcirculatory hemodynamicsfrom ischemia/reperfusion injury: An experimental in vivo study. J Trauma 1997; 42: 74–80
   PubMedGoogle Scholar
• Mohan PF, Jacobson MS. Inhibition of macrophage superoxide generation by dehydroepiandresterone. I Med Sci 1993; 306: 10–15
   PubMed Web of Science ®Google Scholar
• Ress AM, Babovic S, Angel MF, Im MJ, Dellon AL, Manson PN. Free radical damage in acute nerve compression. Ann Plast Surg 1995; 34: 388–395
   PubMed Web of Science ®Google Scholar
• Algora J, Chen L, Seaber AV, Wong GHW, Urbaniak JR. Functional effects of lymphotoxin on crushed peripheral nerve. Microsurg 1996; 17:131–135
   PubMed Web of Science ®Google Scholar
• Li Y, Bickel KD, Im MJ, Hu L, Dellon AL, Vander Kolk CA, Manson PN. Effects of deferoxamine on ischemia/reperfusion injury after peripheral nerve compression. Ann Plast Surg 1996; 36:365–369
   PubMed Web of Science ®Google Scholar
• Ayhan S, Markal N, Siemionow K, Araneo B, Siemionow M. Effect of subepineural dehydroepiandrosterone treatment on healing of transected nerves repaired with epineural sleeve technique. Microsurg 2003; 23:49-55
   Google Scholar
• Aragno M, Parola S, Brignardello E, et al. Dehydroepiandrosterone prevents oxidative injury induced by transient ischemia/reperfusion in the brain of diabetic rats. Diabetes 2000; 49: 1924–1931
   PubMed Web of Science ®Google Scholar
• Huber GC. A study of the operative treatment for loss of nerve substance in peripheral nerves. J Morphol 1895; 11:629–735
   Google Scholar
• Sanders FK. The repair of large gaps in peripheral nerves. Brain 1942; 65:281–287
   Google Scholar
• Miyamoto Y. Experimental study of the results of nerve suture under tension versus nerve grafting. Plast Reconstr Surg 1979; 64: 540–549
   PubMed Web of Science ®Google Scholar
• Karacaoglu E, Yuksel F, Peker F, Guler M. Nerve regeneration through an epineural sheath: Its functional aspect compared with nerve and vein grafts. Microsurg 2001; 21: 196–201
   PubMed Web of Science ®Google Scholar
• Millesi H. Nerve grafting. In: Terzis JK, ed., Clinics in plastic surgery, Ph iladelphia,W.B. Saunders, 1984: pp. 105-120
   Google Scholar
• Scharpf J, Meirer R, Zielinski M, Unsal M, Ram ineni P, Dileep N, Siemionow M. A novel technique for peripheral nerve repair. Laryngoscope 2003; 113: 95-101
   Google Scholar
• Almgren KG. Revascularization of free peripheral nerve grafts: an experimental study in the rabbit. Acta Orthop Scand Suppl 1974; 154:1–104
   Google Scholar
• Ide C, Tohyama K, Yokota R, et al. Schwann cell basal lamina and nerve regeneration. Brain Res 1983; 5: 61
   Google Scholar
• Evans PJ, Midha R, Mackinnon SE. The peripheral nerve al lograft: a comprehensive review of regeneration and neuroimmunology. Prog Neurobiol 1994; 43: 187–233
   PubMed Web of Science ®Google Scholar
• Ishida O, Daves, J, Tsai T, et al. Regeneration following rejection of peripheral nerve allografts of rats on withdrawal of cyclosporine. Plast Reconstr Surg 1993; 92: 916–926
   PubMed Web of Science ®Google Scholar
• Marmor L, Robert M, Foster J. Experimental prevention of nerve homograft rejection by use of immunosuppressive drugs. I Neurosu rg 1967; 27: 415–418
   PubMed Web of Science ®Google Scholar
• Borel JF, Feurer C, Gubler Hu, et al. Biological efffects of cyclosporine A: A new antilymphocytic agent. Agents Actions 1976; 6: 468–475
   PubMedGoogle Scholar
• Zalewski AA, Gulati AK. Survival of nerve and Schwann cells in allografts after cyclosporine A treatment. Exp Neurol 1980; 70: 219–225
   PubMed Web of Science ®Google Scholar
• Bain JR, Mackinnon SE, Hudson AR, et al. The peripheral nerve allograft: A dose response curve in the rat immunosuppressed with cyclosporine A. Plast Reconstr Surg 1988; 82:447–457
   PubMed Web of Science ®Google Scholar
• Bain JR, Mackinnon SE, Hudson AR, et al. The peripheral nerve allograft: An assessment of regeneration across nerve allografts in rats immunosuppressed with cyclosporine A. Plast Reconstr Surg 1988; 82: 1052–1066
   PubMed Web of Science ®Google Scholar
• Bain JR, Mackinnon SE, Hudson AR, et al. The peripheral nerve allograft in the primate immunosuppressed with cyclosporine A: I. Histologic and electrophysiologic assessment. Plast Reconstr Surg 1992; 90: 1036–1046
   PubMed Web of Science ®Google Scholar
• Fish, JS, Bain JR, Mckee N, et al. The peripheral nerve allograft in the primate immunosuppressed with cyclosporineA: II. Functional evaluation of reinnervated muscle. Plast Reconstr Surg 1992; 90: 1047–1052
   PubMed Web of Science ®Google Scholar
• Meirer R, Babuccu O, Unsal M, Nair DR, Gurunluoglu R, Skugor B, Meirer B, Siemionow M. Effect of chronic cyclosporineadmin istra-tion on peripheral nerve regeneration:A dose response study. Ann Plast Surg 2002; 49: 96–103
   PubMedGoogle Scholar
• Mackinnon SE, Doolabh VB, Novak CB, et al. Clinical outcome following nerve al lografttransplantation. Plast ReconstrSurg 2001; 107:1419-1429
   Google Scholar
• Myckatyn TM, Ellis RA, Grand AG, et al. The effects of rapamyc in in murine peripheral nerve isografts and al lografts. Plast Reconstr Surg 2002; 109: 2405–2417
   PubMed Web of Science ®Google Scholar
• Okajima S, Hojo T, Tamai K, et al. Histological and electrophy siological analysis of the peripheral nerve allografts using an immunosuppressive agent. Microsc Res Tech 2002; 58: 52–58
   PubMed Web of Science ®Google Scholar
• Siemionow M, Oke Ramadan, Ozer K, lzycki D, Prajapati R. Induc-tion of donor specific tolerance in rat hind-limb allografts under antilyphocyte serum and cyclosporine A protocol. J Hand Surg 2002; 27A: 1095–1103
   Web of Science ®Google Scholar
• Siemionow M, Ortak T, lzycki D, Oke R, Cunningham B, Prajapati R, Zins JE. Induction of tolerance in composite tissue allografts. Transplant2002; 74: 1211-1217
   Google Scholar