Nanosize titanium dioxide cause neuronal apoptosis: a potential linkage between nanoparticle exposure and neural disorder

References

• Service RF. Nanomaterials show signs of toxicity. Science. 2003;300:243.
   PubMed Web of Science ®Google Scholar
• Oberdörster E. Manufactured nanomaterials (fullerenes, C60) induce oxidative stress in the brain of juvenile largemouth bass. Environ Health Perspect. 2004;112:1058–62.
   PubMed Web of Science ®Google Scholar
• Oberdörste G, Oberdörster E, Oberdörster J. Nanotoxicology: an emerging discipline evolving from studies of ultrafine particles. Environ Health Perspect. 2005;113:823–39.
   PubMed Web of Science ®Google Scholar
• Allen NS, Edge M, Sandoval G, Verran J, Stratton J, Maltby J. Photocatalytic coatings for environmental applications. Photochem Photobiol. 2005;81:279–90.
   PubMed Web of Science ®Google Scholar
• Fisher J, Egerton T. Titanium compounds, inorganic. Kirk-Othmer encyclopedia of chemical technology. New York: John Wiley & Sons; 2001.
   Google Scholar
• Wolf R, Matz H, Orion E, Lipozencic J. Sunscreens-the ultimate cosmetic. Acta Dermatovenerol Croat. 2003;11:158–62.
   PubMedGoogle Scholar
• Kaida T, Kobayashi K, Adachi M, Suzuki F. Optical characteristics of titanium oxide interference film and the film laminated with oxides and their applications for cosmetics. J Cosmet Sci. 2004;55:219–20.
   PubMedGoogle Scholar
• Choi H, Stathatos E, Dionysiou DD. Sol-gel preparation of mesoporous photocatalytic TiO2 films and TiO2/Al2O3 composite membranes for environmental applications. Appl Catal B. 2006;63:60–7.
   Web of Science ®Google Scholar
• Konstantinou IK, Albanis TA. TiO2-assisted photocatalytic degradation of azo dyes in aqueous solution: kinetic and mechanistic investigations: a review. Appl Catal B. 2004;49:1–14.
   Web of Science ®Google Scholar
• Balasubramanian G, Dionysiou DD, Suidan MT, Baudin I, Laîné J-M. Evaluating the activities of immobilized TiO2 powder films for the photocatalytic degradation of organic contaminants in water. Appl Catal B. 2004;47:73–84.
   Web of Science ®Google Scholar
• Esterkin CR, Negro AC, Alfano OM, Cassano AE. Air pollution remediation in a fixed bed photocatalytic reactor coated with TiO2. AIChE J. 2005;51:2298–310.
   Web of Science ®Google Scholar
• Higarashi MM, Jardim WF. Remediation of pesticide contaminated soil using TiO2 mediated by solar light. Catal Today. 2002;76:201–7.
   Web of Science ®Google Scholar
• Baggs RB, Fern J, Oberdorster G. Regression of pulmonary lesions produced by inhaled titanium dioxide in rats. Vet Pathol. 1997;34:592–7.
   PubMed Web of Science ®Google Scholar
• Rahman Q, Lohani M, Dopp E, Pemsel H, Jonas L, Weiss DG, et al. Evidence that ultrafine titanium dioxide induces micronuclei and apoptosis in Syrian hamster embryo fibroblasts. Environ Health Perspect. 2002;110:797–800.
   PubMed Web of Science ®Google Scholar
• Lockman P, Oyewumi M, Koziara J, Roder K, Mumper R, Allen D. Brain uptake of thiamine-coated nanoparticles. J Controlled Release. 2003;93:271–82.
   PubMed Web of Science ®Google Scholar
• Meiring JJ, Borm PJ, Bagate K, Semmler M, Seitz J, Takenaka S, et al. The influence of hydrogen peroxide and histamine on lung permeability and translocation of iridium nanoparticles in the isolated perfused rat lung. Part Fibre Toxicol. 2005;2:3.
   PubMed Web of Science ®Google Scholar
• Kreyling WG, Semmler M, Erbe F, Mayer P, Takenaka S, Schulz H, et al. Translocation of ultrafine insoluble iridium particles from lung epithelium to extrapulmon aryorgans is size dependent but very low. J Toxicol Environ Health A. 2002;65:1513–30.
   PubMed Web of Science ®Google Scholar
• Oberdörster G, Sharp Z, Atudorei V, Elder A, Gelein R, Kreyling W, et al. Translocation of inhaled ultrafine particles to the brain. Inhal Toxicol. 2004;16:437–45.
   PubMed Web of Science ®Google Scholar
• Long TC, Saleh N, Tilton RD, Lowry GV, Veronesi B. Titanium Dioxide (P25) produces reactive oxygen species in immortalized brain microglia (BV2): Implications for nanoparticle neurotoxicity. Environ Sci Technol. 2006;40:4346–52.
   PubMed Web of Science ®Google Scholar
• Block ML, Hong JS. Microglia and inflammation-mediated neurodegeneration: multiple triggers with a common mechanism. Prog Neurobiol. 2005;76:77–98.
   PubMed Web of Science ®Google Scholar
• Colton CA, Chernyshev ON, Gilbert DL, Vitek MP. Microglial contribution to oxidative stress in Alzheimer'sdisease. Ann N Y Acad Sci. 2000;899:292–307.
   PubMed Web of Science ®Google Scholar
• Liu B, Hong JS. Role of microglia in inflammation-mediated neurodegenerative diseases: mechanisms and strategies for therapeutic intervention. J Pharmacol Exp Ther. 2003;304:1–7.
   PubMed Web of Science ®Google Scholar
• Ronnet GV, Hester LD, Snyder SH. Primary culture of neonatal rat olfactory neurons. J Neurosci. 1991;11:1243–55.
   PubMed Web of Science ®Google Scholar
• Bakalyar HA, Reed RR. Identification of a specialized adenylyl cyclase that may mediate odorant detection. Science. 1990;250:1403–6.
   PubMed Web of Science ®Google Scholar
• Matsuzaki O, Bakin RE, Cai X, Menco BP, Ronnett GV. Localization of the olfactory cyclic nucleotide-gated channel subunit 1 in normal, embryonic and regenerating olfactory epithelium. Neuroscience. 1999;94:131–40.
   PubMed Web of Science ®Google Scholar
• Jones DT, Reed RR. Golf: an olfactory neuron specific-G protein involved in odorant signal transduction. Science. 1989;244:790–5.
   PubMed Web of Science ®Google Scholar
• Jimenez LA, Zenela C, Fung H, Janseen YMW, Vacek P, Charland C, et al. Role of extracellular signal-regulated protein kinases in apoptosis by asbestos and H2O2. Am J Physiol. 1997;273:1029–35.
   PubMed Web of Science ®Google Scholar
• Moore DJ, West AB, Dawson VL, Dawson TM. Molecular pathophysiology of Parkinson's disease. Annu Rev Neurosci. 2005;28:57–87.
   PubMed Web of Science ®Google Scholar
• Davila NG, Blakemore LJ, Trombley PQ. Dopamine modulates synaptic transmission between rat olfactory bulb neurons in culture. J Neurophysiol. 2003;90:395–404.
   PubMed Web of Science ®Google Scholar
• Serretti A, Macciardi F, Verga M, Cusin C, Pedrini S, Smeraldi E. Tyrosine hydroxylase gene associated with depressive symptomatology in mood disorder. Am J Med Genet. 1998;81:127–30.
   PubMed Web of Science ®Google Scholar
• Pignatelli A, Kobayashi K, Okano H, Belluzzi O. Functional properties of dopaminergic neurones in the mouse olfaxtory bulb. J Physiol. 2005;564:501–14.
   PubMed Web of Science ®Google Scholar
• Farbman AI, Margolis FL. Olfactory marker protein during ontogeny: immunohistochemical localization. Dev Biol. 1980;74:205–15.
   PubMed Web of Science ®Google Scholar